Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name Has1P1
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Plot displaying the genomic locations of a retrocopy (in chr19) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Rattus norvegicus
Coordinates chr19:39071920-39072102  UCSC
Strand +
Parental Sequence NM_172323.1
Parental seq. overlap 146 bp
Parental seq. overlap (%) 7%
Genomic Region Intragenic (Has3)
Retrocopy Summary Has1P1, located on chr19:39071920-39072102, is a retrocopy of the parental gene Has1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Has1
Full Name hyaluronan synthase 1
Also known as -
Coordinate chr1:59720612-59732409
Strand -
Gene summary Predicted to enable hyaluronan synthase activity and identical protein binding activity. Involved in estrous cycle. Predicted to be located in cytoplasm and membrane. Predicted to be integral component of plasma membrane. Biomarker of pulmonary hypertension. Orthologous to human HAS1 (hyaluronan synthase 1). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Mouse lemur Microcebus murinus HAS1P1
Pig Sus scrofa HAS1P1
Cow Bos taurus HAS1P1
Sheep Ovis aries HAS1P1
Dog Canis familiaris HAS1P1
Panda Ailuropoda melanoleuca HAS1P1
Pale spear-nosed bat Phyllostomus discolor HAS1P1
Kuhl's pipistrelle Pipistrellus kuhlii HAS1P1
Greater horseshoe bat Rhinolophus ferrumequinum HAS1P1
Egyptian rousette Rousettus aegyptiacus HAS1P1
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse Mus musculus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Cat Felis catus Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

This retrocopy transcript is not present in the database for expression quantification

Related Sequence

>Has1P1
GTACTGGATGGCCTTCAACGTGGAGCGGGCCTGCCAGTCCTACTTTGGCTGTGTGCAGTGTATTAGTGGGCCTCTGGGCATGTACCGCAACAGCCTCCTTCAGCAGTTCCTGGAGGACTGGTACCATCAGAAGTTCCTAGGCAGCAAGTGCAGCTTTGGGGATGATCGGCACCTTACCAACCG
>NM_172323.1
AGAGCAAGTCGGAAAAGAGAAAATCCAGGAGGACCCACAGCCATGAGACAGGACATGCCAAAGCCCTCAGAGGCAGCACGTTGCTGCTCCGGTCTGGCCAGGCGGGTGCTCACGATCACCTTCGCCCTGCTCATCCTGGGCCTCATGACCTGGGCCTACGCAGCAGGAGTAcctctggcttctgatccctatggcctcctggcctttgggctctATGGGGCGTTCCTCAGTGCGCACCTAGTGGCACAGAGCCTCTTCGCTTACCTGGAGCACCGAAGGGTGACCGTGGCTGCGCGGCGCGCTTTTGCGAAGGGACCCCTGGATGCGGCCACTGCGCGCAGCGTGGCACTCACCATCTCAGCCTACCAGGAGGACCCCACTTACCTGCGCCAGTGCTTGACCTCCGCGCGCGCCTTGCTGTACCCGCGCACGCGGCTGCGCGTGCTTATGGTTGTAGACGGCAATCGCGCGGAGGATCTGTACATGGTGGACATGTTCCGAGAAGTCTTCGCAGATGAGGACCCTGCCACTTATGTGTGGGATGGCAACTACCATCAGCCTTGGGAGCCAGCTGAGGCGGCGGGTGCTGTGGGTGAAGGTGCCTACCGCGAGGTGGAGGCTGAGGACCCTGGGCGGCTGGCGGTAGAGGCGCTGGTGAGGACCCGCAGGTGCGTGTGCGTGGCTCAGCGCTGGGGTGGCAAGCGCGAAGTCATGTACACGGCTTTCAAGGCACTGGGTGACTCCGTGGACTACGTGCAGGTCTGTGACTCAGACACAAGGTTAGACCCCATGGCACTGCTGGAGCTTGTGCGAGTGCTGGATGAAGACCCCCGGGTAGGTGCTGTTGGAGGAGATGTGAGAATCCTTAACCCTCTGGACTCTTGGGTCAGCTTCTTGAGCAGCCTTCGATACTGGGTAGCCTTCAATGTGGAGCGAGCTTGTCAGAGCTACTTTCACTGTGTGTCCTGCATCAGTGGTCCTCTGGGTCTATACAGAAACAATCTCCTGCAGCAGTTCCTGGAGGCCTGGTACAACCAGAAGTTCCTGGGCACCCACTGCACATTTGGGGATGACAGGCACCTCACCAACCGCATGCTTAGCATGGGCTACGCTACCAAGTATACCTCGCGCTCCAGATGCTATTCAGAGACGCCCTCCTCTTTCCTTCGTTGGCTGAGCCAGCAGACCCGCTGGTCCAAATCTTATTTCCGAGAGTGGCTATACAACGCCCTGTGGTGGCACCGCCACCACGCGTGGATGACCTATGAAGCGGTGGTTTCTGGCCTCTTCCCTTTCTTTGTGGCTGCCACGGTGCTGAGGCTCTTCTATGCAGGGCGCCCATGGGCTCTGCTCTGGGTGCTGCTCTGCGTGCAGGGCGTGGCACTGGCAAAGGCAGCCTTTGCAGCCTGGCTGCGTGGCTGCCTGCGCATGGTGCTGCTGTCACTCTATGCACCACTCTACATGTGCGGCCTGCTGCCTGCCAAGTTCCTGGCGTTGGTTACCATGAATCAAAGTGGTTGGGGCACCTCGGGCCGGAAGAAACTGGCTGCTAACTATGTACCCGTGTTGCCCCTGGCACTCTGGGCTCTACTGCTGCTTGGAGGCCTGATCCGCAGTGTGGCCCAGGAGGTCAGAGCTGACTGGAGTGGCCCATCACGAGCAGCTGAAGCCTACCACCTTGCTGCTGGGGCCAGTGCCTATGTGGCCTACTGGGTGATAATGTTGACTATCTATTGGGTAGGTGTAAGGAGACTGTGCAGACGTCGGAGCGGTGGCTACCGTGTCCAAGTATGAGTCTGGGTATGAAGATGCCCCTGAGGGCTGTTAAAAGAGGCAAGAGGAGTCCTTATGAGGTAGCCCTGGAGCCACGGATTTCATGGGGACTGAGTTTACCTTCTTTTTGAAAAGAGGAATCATTACAGATTCTTCACTATGGACTGTATTGGAATTCTGACTTCTCGGTCTCTGGGGAGGGGTAATTTATTGATCAGGGAGTGGGATTATAGGACCAGGGTCAGAAGGCCTCTGCTTTCTCCCTGTTGCTATTTAATGTTTGTACTGTAAGATATAATAAAATTTTTTAATTTATTTTCTTC

Publications

PMID - Link Title
No publications available for this retrocopy