Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name Hnrnph1P3
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr10). Each line represents a retrocopy.
Species Rattus norvegicus
Coordinates chrX:105421562-105422736  UCSC
Strand +
Parental Sequence NM_080896.1
Parental seq. overlap 1016 bp
Parental seq. overlap (%) 52.6%
Genomic Region Intergenic
Retrocopy Summary Hnrnph1P3, located on chrX:105421562-105422736, is a retrocopy of the parental gene Hnrnph1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Hnrnph1
Full Name heterogeneous nuclear ribonucleoprotein H1
Also known as Hnrph|Hnrph1|hnRNP H
Coordinate chr10:35872619-35879911
Strand +
Gene summary Enables enzyme binding activity. Involved in cellular response to peptide. Located in nucleoplasm. Is active in postsynaptic density. Human ortholog(s) of this gene implicated in Sjogren's syndrome. Orthologous to human HNRNPH1 (heterogeneous nuclear ribonucleoprotein H1). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Gibbon Nomascus leucogenys HNRNPH1P4
Green monkey Chlorocebus sabaeus HNRNPH1P5
Crab-eating macaque Macaca fascicularis HNRNPH1P6
Rhesus Macaca mulatta HNRNPH1P7
Baboon Papio anubis HNRNPH1P6
Golden snub-nosed monkey Rhinopithecus roxellana HNRNPH1P3
Marmoset Callithrix jacchus HNRNPH1P8
Mouse Mus musculus Hnrnph1P7
Chinese hamster Cricetulus griseus Hnrnph1_1P4
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Mouse lemur Microcebus murinus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>Hnrnph1P3
CGAACTCGAATCTGAAGATGAAGTGAAATTGGCTTTAAAGAAAGACAGAGAAACCATGGGACACAGATATGTTGAAGTATTCAAATCCAACAGTGTTGAAATGGATTGGGTGTTAAAGCATACAGGTCCAAATAGTCCTGATACTGCCAATGATGGGTTTGTACGGCTCAGAGGACTCCCATTTGGCTGTAGCAAGGAAGAAATTGTTCAGTTCTTTTCAGGGTTGGAAATTGTGCCAAATGGGATGACACTGCCAGTGGACTTTCAGGGGCGGAGCACAGGGGAAGCTTTTGTGCAGTTTGCTTCACAGGAGATAGCTGAAAAGGCCTTAAAGAAACACAAGGAAAGAATAGGGCATAGGTACATCGAGATCTTCAAGAGTAGCAGAGCTGAAGTCCGAACCCACTATGATCCCCCTCGAAAGCTCATGACTATGCAGCGCCCGGGTCCTTATGATAGGCCAGGGGCTGGGAGAGGGTATAATAGCATTGGCAGAGGAGCTGGGTTTGAAAGAATGAGGCGGGGTGCCTATGGTGGAGGGTACGGAGGCTATGATGACTACGGAGGTTATAATGACGGGTATGGTTTTGGGTCTGATAGATTTGGAAGAGACCTAAACTACTGTTTCTCAGGAATGTCTGATCATCGATATGGAGATGGTGGGTCCAGTTTCCAGAGCACCACAGGGCACTGTGTACACATGAGGGGGTTACCATACAGAGCCACTGAGAATGATATTTACAATTTTTTCTCACCTCTTAATCCCATGAGAGTACACATTGAAATCGGACCTGATGGCAGAGTCACGGGTGAGGCAGACGTTGAGTTTGCTACTCATGAAGACGCTGTGGCAGCTATGGCAAAAGATAAAGCAAATATGCAGCACAGATATGTGGAGCTCTTCCTGAATTCTACCGCAGGGACGAGTGGAGGAGCTTATGATCATAGCTATGTAGAGCTCTTTTTGAATTCTACAGCAGGGGCAAGCGGTGGTGCTTATGGCAGCCAGATGATGGGAGGGATGGGTTTATCCAACCAGTCTAGTTATGGAGGTCCAGCCAGCCAGCAGCTGAGTGCTGGCTACGGAGGTGGTTATGGTGGTCAGAGCAGTATGAGCGGATATGACCAAGTTCTTCAGGAAAACTCAAGTGACTATCAGTCAAACCTTGCTTAGG
>NM_080896.1
GTTGAACTTGAATCAGAAGATGAAGTCAAATTGGCCTTGAAAAAAGACAGAGAAACTATGGGACACAGATATGTTGAAGTATTCAAGTCAAACAACGTTGAAATGGATTGGGTGTTGAAGCATACTGGTCCCAATAGTCCTGACACGGCCAATGATGGCTTTGTACGGCTTAGAGGACTCCCTTTTGGATGTAGCAAGGAAGAAATTGTTCAGTTCTTCTCAGGGTTGGAAATCGTGCCAAATGGGATAACATTGCCGGTGGACTTCCAGGGGAGGAGTACGGGGGAGGCCTTCGTGCAGTTTGCTTCACAGGAAATAGCTGAAAAGGCTCTAAAGAAACACAAGGAAAGAATAGGGCACAGGTATATTGAAATATTTAAGAGCAGTCGAGCTGAAGTTAGAACTCATTATGATCCACCACGAAAACTTATGGCCATGCAGCGGCCAGGTCCCTATGACAGACCTGGGGCTGGCAGAGGGTATAACAGCATTGGCAGAGGAGCTGGCTTTGAGAGGATGAGGCGTGGTGCTTATGGTGGAGGCTATGGAGGCTATGATGATTATAATGGCTATAATGATGGCTATGGATTTGGTTCGGATAGATTTGGAAGAGACCTCAATTATTGTTTTTCAGGAATGTCTGACCACAGATATGGGGATGGTGGCTCCACTTTCCAGAGTACAACAGGACACTGTGTACACATGCGGGGATTACCATACAGAGCTACTGAGAATGACATTTATAATTTTTTTTCACCACTCAACCCTGTGAGAGTACATATTGAGATTGGACCTGATGGCAGAGTAACTGGTGAAGCAGATGTTGAGTTTGCAACCCATGAAGATGCTGTTGCAGCTATGTCAAAAGATAAAGCAAATATGCAACACAGATATGTAGAACTCTTCTTGAATTCTACAGCAGGAGCAAGCGGTGGTGCTTACGAACACAGATATGTAGAACTCTTCTTGAATTCTACAGCAGGAGCAAGCGGTGGTGCTTATGGTAGCCAAATGATGGGAGGCATGGGCTTGTCAAACCAGTCCAGTTACGGTGGCCCAGCCAGCCAGCAGCTGAGTGGTGGTTATGGAGGTGGCTATGGTGGCCAGAGCAGCATGAGCGGATATGACCAAGTTTTACAGGAAAACTCCAGTGATTTTCAATCAAACATTGCATAGGTAGCCAAGGAGCAGTGAACAGCAGCTACTACAGTAGCGGAAGCCGTGCATCTATGGGCGTGAATGGAATGGGAGGGATGTCTAGCATGTCTAGTATGAGTGGTGGATGGGGAATGTAATTGATTTTGATCACTGACTCTTGGTCAAAAAGAAATTTTTTTAAAACCCTTCAGTTTAACAGTTTTTGCAATCCAGCCTTGTGGTTTTAATGCCTGCTCTCTTAAGTGAACTTTGGCATCGATCGCTCAAAGAAGGTTCAATGTTGAACATAGCAGTCACCTAGGATGATAGGGCAAAGTTGAGTAACTTTAACTGTTAAACTTAATTCCTAGCTTTTCTCTAGTTATGTAGGATGTACGTAAGCAGTAAGTGTATTTAGGTTAAAGCAGTTGAATTATGTTAAATGTTGCTCTTATACATACATACATTGAACACTGTTGATGCATGTTGAAAAGACATGCTTTTTTTGTAAAACTATAGGAGCTGCGTCTACAATTAAAAGTGAAACATTTGGCATGTTTGTTAATTCTAAATTCATTTGATAACCTGTAAGGCACGTGAGTTTAAAGCTCTTTTCTTTTTTTAAGTTAATGGAGAAATTCTGAGACGCAATACCATTACTTTTTAGGATTTTTGGTCTTGGTGTTTGTACGAAATTCTGAGGCCTTGATTTAAGTCTTTCATTGTATTGTGATTTACTTTTAGGTGTATTGCGCTAAGTGAACCTTGTCAAATAAATCTTCCTTTTAAAAGCTA

Publications

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