Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name Rnf115P1
Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Rattus norvegicus
Coordinates chr14:97901380-97902500  UCSC
Strand +
Parental Sequence XM_006232975.1
Parental seq. overlap 989 bp
Parental seq. overlap (%) 44.8%
Genomic Region Intergenic
Retrocopy Summary Rnf115P1, located on chr14:97901380-97902500, is a retrocopy of the parental gene Rnf115. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Rnf115
Full Name ring finger protein 115
Also known as Zfp364
Coordinate chr2:198852392-198920000
Strand +
Gene summary Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in negative regulation of epidermal growth factor receptor signaling pathway; protein ubiquitination; and ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway. Predicted to be located in cytosol. Orthologous to human RNF115 (ring finger protein 115). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>Rnf115P1
TGCTCTGGGACCATTTGGGTCACACAATGTTTTTACAAAATTTTAGACCATTATTAAGTAGCAATCCACTGGACCAAGACAATAGAGCCAATGAGAGAGGTCACCATACTCACACTGACATTTGGAGACCAAGATGCCCTCCAAGGTTGTCTATGACAAGAAGATACAGGTCTCCAAGGAAGTACTAGTCCTGACATGTCACCAGCTATTGAAGGAATTACACAACTGATCTTTGTAAGATTCTTTGCACATTCTGACGTTCCTGGGTGCCCACAACCCTTTTCTTGGAGCAAGATGCTGCACTCTAACCCTGGGGACTATGCCATTGTAACCCAGTTTCTAGGTCAGCTAGAAAATACAGGTCCCCCTCCTCCTGACAAGGAGAAGATCCTATCTCTCCTAAGAGTGATAGTAACTCAGGAACAAGTCAATATAGGTTTAGAATATGCAAAGATTACACAGGGGAGGAGAAAGTCGGCAGTTATCCTACAACCACTTCTTTCACAGAAGCTACATCATGTGGTGGTAGTTAGAACTGCATGACACATGCCCAGTATGTACAAAGAGCTTAAATGGTGAGGACACTACTCAGCAAACCCAGAGCTCTGAGCAAGCAGCAGATTTAGCAATGACAGGCAGCTACACGATTGACAGACTTTATGAAATTAAAGACCACACCTGAACCAGGTTTGCCTGTGTTAGTACTGTTATCATAGCTGTAAATTATATCAAAACTAAACAAACAAAATAGTAGGTGGATTTGGGGATCATGTAAGAAACCCCAGCTTATAATATTAATTCTATGAGTGTATTTCTTCTCTAAATTAAAGTTAGGACCTACAGATGGAATTGTATAGATAACCAAATGCATCTTGTTGCTGAATTGAATGATAGTTTCATAAGTGTGAAACTTAATTATGTCAGTTGTTCCTGCCTGAGTAGAATCAATTCTTTAAAGTTAAGGTAGGGTTCTGCTCTCATGTGGTATTGTAATGGATTCTCTACCTCCTCCTCCAATCTCTATCCTACCATTAGTGGATTTCCCAGCAAATACAGACAAGCCAAAGCCCCAAGGTCCTGTTTTATAAAGCCTTTTTTTCTTAATTGTACAAGGGTACAAG
>XM_006232975.1
GGGGCCGGGCGGACTCACGTGACCCTTGCGGGCCTTGGAgcggcgggccgcccagaggaggcggcgacggcggcggcggcggcggcgaccgcagcCCAGGAGGTAGCGGCCTGGGGAGGGACCGCCGGCCGCCCTTTCGGACATCCTCCGCAGAGGCGAAAAATggcggaggcctcggcggcgggggcggacgcgggctccgctgtcgccgcgCACCGTTTCTTCTGCCACTTTTGTAAGGGCGAGGTCAATCCCAAACTACCGGAATATATATGTCCCAGATGTGAATCAGGCTTTATTGAGGAAGTGACAGATGATTCCAGTTTCTTAGGTGGTGGTGGAAGCCGGACAGACAATAGCACAGCAACACATTTTGCCGAGCTCTGGGACCATCTGGATCACACAATGTTTTTACAAGATTTTAGACCATTTCTAAGTAGCAATCCTCTGGACCAAGATAATAGAGCCAATGAGAGAGGTCACCAAACTCACACTGACTTTTGGGGACCAAGTCGGCCTCCAAGGTTGCCTATGACAAGAAGATACAGGTCTCGAGGAAGCACTCGTCCTGACAGGTCGCCAGCTATCGAAGGAATAATACAACAGATCTTTGCAGGATTCTTTGCAAATTCTGCCATTCCTGGGTCCCCACACCCCTTTTCTTGGAGCGGGATGCTGCACTCCAACCCTGGGGACTATGCCTGGGGTCAGACAGGGCTTGATGCCATTGTAACCCAGCTTCTAGGACAGCTGGAAAACACAGGGCCCCCTCCAGCTGACAAGGAGAAGATCACGTCTCTGCCAACAGTGACAGTAACTCAGGAGCAAGTCAATACGGGTTTAGAATGTCCAGTATGTAAAGAAGATTACACAGTTGAGGAGAAAGTCCGGCAGTTACCCTGCAACCACTTCTTTCACAGCAGCTGCATCGTGCCCTGGTTAGAACTGCATGACACATGTCCAGTATGTAGGAAGAGCTTAAATGGTGAGGACTCGACTCGGCAAACCCAGAGCTCCGAGGCCTCTGCAAGCAACAGGTTTAGCAATGACAGCCAGCTACACGACCGATGGACTTTCTGAAACTAAAGACCACACCCGAACCAGGGCTGCCTGTGTTAGTCCTGTTGTCATAGCTGTAAATTGTATCAAAACTAAACAAACAAAATAGTAGATGGATTTAGGAATCATGTAAGAGACTCAAACCCATAATATTAATGCAATGAGTGTATTTCTTCTCTAAATTTAAAGTTAGGGCTTACAGATGGAATCGTATTGACAACCAAATGCCTCTTGTTCCTGAATTGAGTGATAGTTTTCTAAGTGTGAAACTTAATTATGTCAGTTTGCTCCTGCCTGAGTAGAATCAATTCCGTAAAGTCTAGGTAGGTTCTGCTGTCATGTTGTCTAGTAATGGATGGCTCTACCTCCTCCTCCTGTCTCTGTCCTACCATTAGTGGATTTCACAGCAAATACAGACAAGCCAGAGCCCTCAGGTCCTGTCATATAAAGCCTTTTTTCTTAATTGTACAAGAGTACAAGTACACACTTCAGGAATCTGAGACTCTAATGCTGTCTTGTCTTGATCATCAGAGAGCAATTCCAGTGGGAAGGAGAAACGACGGCCTGCACTGTCCACGTGGGCTTTCTTATTTTAGTTCAGGAAGTACAGTTTCCCTAAAAACCACCATGGCATGTCTTAGTTTTGGGTTGGTAGAAATCTGATTTTGGTTTCTCTGTGACATTAGATTGAGCAGCATATAGATGTGGAAAGACAGATGTGGGAGACTTTACTACTGCGATATTTTTTAATGACCCTCAACTCATTGTTTATTGTCTTTCATACTAGGAACCTTATAATAATTTTCTTCATAAAATTAATTTCCTTCAAAAATACAATAAATTCCTTCATAAAAAATAGGATTATTTTATTACTGTTTCTATACCAGTTCACAGTTCTGGTAATTCATTGTTATTTAGGAATTAACATTGTGTGTTGTCTTGTTTTAGTTTGTACAGCCCATTTTTCATGTCTGAAACTTTGCCTGTTCTGTTCAGTTCTAGCTGTACTTGGAATCAATCTGATCAATGTAATCATGCCCAAAACAACTTAGTTTGGGAAAGGTAAACCTTGTTTTAAATTCTAACAATGCTCATACGCATACTCTGTACATGTTTACAATGGAATAAATGGAGATTGTGGAGCA

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