Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name Slc25a1P1
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Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Rattus norvegicus
Coordinates chr11:26663466-26664602  UCSC
Strand +
Parental Sequence NM_017307.3
Parental seq. overlap 1042 bp
Parental seq. overlap (%) 62.8%
Genomic Region Intergenic
Retrocopy Summary Slc25a1P1, located on chr11:26663466-26664602, is a retrocopy of the parental gene Slc25a1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Slc25a1
Full Name solute carrier family 25 member 1
Also known as Cic|Ctp|Slc20a3
Coordinate chr11:87204248-87207265
Strand +
Gene summary This gene encodes a member of the mitochondrial carrier family. The encoded protein is responsible for the movement of tricarboxylates, such as citrate, across the inner mitochondrial membrane. It is essential to the bioenergetics of hepatic cells, supplying the cytoplasm with a carbon source for fatty acid and sterol biosynthesis, and NAD+ for the glycolytic pathway. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>Slc25a1P1
AGGCAGAAGCAGTGATAGCCATGTGCCCCATGGGGACCATCAAGGTGAAATTCAGCCATGACCAGACTTCCTCTAACCCCAAGTACGGAGGATTTTTCCACGGGGTTAGAGAGATTATTCTGGAACAAGGGCTAAAGGAGACATACCAAGGCCTCACAGCTACTGTACTAAAGCAGGGCTCAAACCAACCCATCCGATTCTTCGTCGCGACCTCCCTACGCAACTGGTACCAAGGAGACAACCACAACAAACCTATGAACCCACTGATCACGGGGATCTTTGGAGCTGTTGCGGGTGCTGCCAGTGTCTTTGGAAACACATCCTTGGATGTGATCCAGACTAGGATACAGGGCCTGGAGGCACACAAATACGGGAACACGCTGGACTGTGGCATGCAGATCCTGAAGAATGAGGGCCCAAGGCATTCTACAAGGGCACCGTTCCCCGCTGGGCCGAGTCTGCCTGGACGTGGCCATCATATTCGTCATCTATGATGAAGTGGTGAAGCTGCTTAATAAAGTGTGGCAGACAGACTAACCCTGGAGGGTACAGTGGGGTGTCCCAGCTCCTCCAGGCCAGACCCTCACCACCTACTCTGATGATTCCAGTGCAGTAGTGCCAAAGGGCCCCCTCCTTTGTCCCTCAAGTTCTGTGGCCTGGTGTGTCATAGTGAGACTGTCATGTGTTCCTTAGTTCTGTACTCCCATGTGGTCTATGTGTAACACTACTATTGTATCTGTGTCCAGCCTGGCCGTGGCTGGGTGTCTCTTTGACCGGTGAAGATGTGCTAACTTACCCATGTGCTTGCCTGTGAGCCATGTGCCTGTTTCATGTTCTATATCATGTGACCCTGTGCCCCACCTCATGGGGTCCTATGTGCCCTGGTCCATGGTCTTGGAGCCATGGTCAGGTCACAGTCCTTCCACTCCCTATAGCAAGGGCGTCCTGGCCTGGCCTACCAAAGCTGCCTTTCAGCTTCCGCCTGGCTTCACCACATTCCAGGGGCTATAGGCCCTCCTGCCTCTCCCGCCATTGGCTTTAAATGGCCCTCATGCCCTCCCAGTCTCTGCTCAGAGCAGGGTGGCACTGGCCACTCTCAGGACCACCTTGCCAAGGAGAATAAACTGGATCCTGTTG
>NM_017307.3
CGGGACCAGAATTGGTCGCGGTCTCTGTAGCCTCCGGCCCCGTTGCTTTCCGAGTGCCCCGCGCCGGAGGCTCGGACCCGAGGTCGACGCCGGGCGCCCCTCCTCCTGCCCGCCATGGCTGCGCCTCGCGCACCCCGCGCTCTGACGGCTGCCGCTCCCGGGTCCGGGAAAGCCAAACTGACGCACCCCGGGAAGGCGATCCTAGCAGGCGGCCTGGCTGGAGGCATCGAAATCTGCATCACCTTCCCGACCGAATACGTGAAGACTCAACTACAGCTAGATGAACGCGCGAACCCACCGCGGTACCGGGGCATTGGGGACTGCGTGCGGCAAACTGTCCGCAGCCATGGCGTCCTGGGCCTGTACCGCGGCCTCAGCTCCTTGCTCTACGGCTCCATCCCCAAGGCGGCTGTCAGGTTTGGGATGTTCGAGTTCCTCAGCAACCACATGCGGGATGCCCAAGGTAGACTGGACAGCAGGAGAGGACTGCTGTGCGGTCTGGGTGCCGGCGTGGCAGAGGCAGTGGTAGTCGTGTGCCCCATGGAGACCGTGAAGGTGAAATTCATCCATGACCAGACTTCCTCCAATCCAAAGTACCGAGGATTTTTCCATGGGGTTAGAGAGATTGTTCGGGAACAAGGGCTAAAGGGGACATACCAAGGCCTCACAGCTACTGTACTGAAGCAGGGCTCAAACCAAGCCATCCGATTCTTCGTCATGACCTCCCTACGCAACTGGTACCAAGGAGACAACCCCAACAAGCCTATGAACCCACTGATCACCGGGGTCTTTGGAGCTGTCGCAGGTGCAGCCAGTGTCTTTGGGAACACACCCTTGGATGTGATCAAGACCAGGATGCAGGGCCTGGAGGCACACAAATACCGGAACACCCTGGACTGTGGAGTGCAGATCCTGAAGAATGAGGGGCCCAAGGCATTCTACAAGGGCACCGTTCCCCGGCTGGGCCGAGTCTGCCTGGACGTGGCCATCGTATTCGTCATCTATGATGAAGTGGTGAAGCTGCTCAATAAAGTGTGGAAGACGGACTAACCCTGGAGGGTGCAATGGGGCGTCCCAGCTCCTCCAGGCCACCTACTCTTGACGATTCCAGTGCAGTAGTGCCAAAAGGCCCCTTCCTTTGTCCCTCAAGTTCTGTGGCCTGGTGTGTCATAGTGACTGTCATGTGTTCCTTAGTACTGTACTCCCATGTGGTCTATGTGTAACACTACTATTGTATCTGTGTCCAGCCTGGCCGTGGCTGGGTGTCTCTTTGGCCTGTGAAGACGTGCTCACTTACCCATGTGCTTGCTTGTGAGCCATGTGCCTGTTTCATGTTCTATGTCATGTGACCCTGTGCCCCACTTCCTGGGGTGCCTATGTGCCCTGGTCCATGGCCTTGGAGCCATGGTCAGGTCACAGTCCGGTGCCTTCCACCCCCTATGGCAAGGGCGCCCTGCCCTGGCCTACCACAGCTGCCTCTGGGCTTCGGCCTGGCTTCACCGCATTCCAGGGGCTATAGGCCCCCCTGCTTCTCCCGCCATTGGCCTTAAATGGCCCTCGGGCCCTCCCTCTGCCCGGAACAGGGTGGCACCAGCCACTCTCAGGACCACCTTGCCAAGGAGAATAAACCGGATCCTGTTGCA

Publications

PMID - Link Title
No publications available for this retrocopy