Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name GAPDHP6
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Macaca mulatta
Coordinates chr1:192253537-192254597  UCSC
Strand +
Parental Sequence XM_028828781.1
Parental seq. overlap 886 bp
Parental seq. overlap (%) 65.7%
Genomic Region Intergenic
Retrocopy Summary GAPDHP6, located on chr1:192253537-192254597, is a retrocopy of the parental gene GAPDH. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name GAPDH
Full Name glyceraldehyde-3-phosphate dehydrogenase
Also known as -
Coordinate chr11:6685663-6689624
Strand +
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Human Homo sapiens GAPDHP20
Chimpanzee Pan troglodytes GAPDHP5
Bonobo Pan paniscus GAPDHP3
Gorilla Gorilla gorilla GAPDHP5
Orangutan Pongo abelii GAPDHP6
Gibbon Nomascus leucogenys GAPDHP27
Green monkey Chlorocebus sabaeus GAPDHP35
Crab-eating macaque Macaca fascicularis GAPDHP6
Baboon Papio anubis GAPDHP4
Golden snub-nosed monkey Rhinopithecus roxellana GAPDHP41
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>GAPDHP6
TACCAGGGCTGCTTTTAACTCTAGCAAAGTGGATAGTGTCACCATCAATGACCACTTCATTCAGGTCAACTCCATGGTCTACATGTTCCAGTATGATTCCACCCATGACAAGTTCCATGGCACCATCAAGGCTGAGAACGAGAAGTTTGTCATCAGTGGAAATCCCATCACCATCTTCCAGGAACAAAATCCTATCAAAATCAAATGGGCTGGTCCTGATGCTGGTTATGTTGTGAAGTCCACTGGCCTCTTCACTGCCTTGGAGAACACTGGGGCTCACTTAGAGGGTGCAACCAAAGGGGTCATCTCTGCCCTCTCTGTTGATGTCCCCATGTTTGTGATGGGCGTGAACCTTGAGAAGTATGAAAACAACCTCGTGATTGTCAGCAATGCTTCCTGTACTGCCAACTGCTTAGCTATCCTGCCCAAGGTCATCCATGACAACTTTGGCATCATGGAGGGACTCATGGCCACAGTTGGTGCCAACATTGCCACCCAGAAGATTGCGGATGGCCTCTCTGGGAAACTGTGGCATGATGGCCACAAGACTCTCCAGGACATCATCCCTGCATTTACCCACTCTGCCAAGGCTGTGGGCAAGGCCATCCCTGAGCTTAACAGAAAGCTCTCTGGCATGGCCTTCCATGTCTTCATTGCCAACATGTGGGTTGTGGACCTGATCTGCCATCTGGAGAGAGCTGCCAAATATGATAACATCAAGAAGGTGGTGAAGCTGGCATCAGAGGCCCCCCTCAAGGGCCTCCTGAGCTACACTGAGCAGTAGGTTGTCTCCTCCAACTTTAACAGAGACACCCACCTTTTTCACCTTAGATCCTGGGAATGGCATTGTCCTCAGTGACCGCTTTGTCAAGCTCATTTCCTGATATGACAATGAATTTGGCTACAGCAACAGAACGATATACCTTATGGTCTACATGGCTTCCAAGGAGTAAGAGCCCTCTGAACCACTAGCCCCAATGACAGCACGAGAGGAAGAGAGGCCCTCAGCTGCTGGGGAATCCCTGCCAAACTCAGTCCCCCACGACACTGAGAATCTCCCC
>XM_028828781.1
AGCCGCATTTTCTCTTGCATCGCCAGGTGAAGACGGGCGGAGAGGAGCCCGGAGGCTAGGGACGGGCCTGAAGGCGGCAGGAGCGGGCGTGGGCCGGACGTGTTCGCGCCGCTGCGGGCGCATCCCTGAGACACCATGGGGAAGGTGAAGGTCGGAGTCAACGGATTTGGTCGTATTGGGCGCCTGGTCACCAGGGCTGCTTTTAACTCTGGTAAAGTGGATATTGTTGCCATCAATGACCCCTTCATTGACCTCAACTACATGGTTTACATGTTCCAGTATGATTCCACCCATGGCAAGTTCCATGGCACCGTGAAGGCTGAGAACGGGAAGCTCGTCATCAATGGAAGCCCCATCACCATCTTCCAGGAGCGAGATCCCTCCAAAATCAAGTGGGGCGATGCTGGCGCTGAGTACGTCGTGGAGTCCACTGGCGTCTTCACCACCACGGAGAAGGCTGGGGCTCATTTGCAGGGGGGAGCCAAAAGGGTCATCATCTCTGCCCCCTCTGCTGACGCCCCCATGTTCGTCATGGGTGTGAACCATGAGAAGTATGACAACAGCCTCAAGATCGTCAGCAACGCCTCCTGCACCACCAACTGCTTAGCACCCCTGGCCAAGGTCATCCATGACAACTTTGGTATCGTGGAAGGACTCATGACCACAGTCCACGCCATCACTGCCACCCAGAAGACTGTGGATGGCCCCTCCGGGAAACTGTGGCGTGATGGCCGCGGAGCTCTCCAGAACATCATCCCTGCCTCTACTGGCGCTGCCAAGGCTGTGGGCAAGGTCATCCCTGAGCTGAACGGGAAGCTCACTGGCATGGCCTTCCGTGTCCCCACTGCCAACGTGTCAGTGGTGGACCTGACCTGCCGTCTGGAAAAACCTGCCAAGTACGATGACATCAAGAAGGTGGTGAAGCAGGCGTCGGAGGGCCCCCTCAAGGGCATCCTGGGCTACACTGAGCACCAGGTGGTCTCCTCCGACTTCAACAGCGACACCCACTCTTCCACCTTCGACGCTGGGGCTGGCATTGCCCTCAACGACCACTTTGTCAAGCTCATTTCCTGGTATGACAACGAATTTGGCTACAGCAACAGGGTGGTGGACCTCATGGCCCACATGGCCTCCAAGGAGTAAGACCCCCGGACCACCAGCCCCAGCGAGAGCACAAGAGGGAGAGAGAGGCCCTCACTGCTGGGGAGTCCCTGCCACACTCAGTCCCCCGCCACACTGAATCTCCCCTCACAGTTTCCATGTAGACCCCTTGAAGAGGGGAGGGGCCTAGGGAGCCCCACCTTGTCGTGTACCATCAATAAAATCCCCTGTGCTCAGCCA

Publications

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