Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PPP1R1AP1
Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Macaca mulatta
Coordinates chr14:68972452-68972914  UCSC
Strand -
Parental Sequence NM_001266966.1
Parental seq. overlap 404 bp
Parental seq. overlap (%) 23.7%
Genomic Region Intragenic (UVRAG)
Retrocopy Summary PPP1R1AP1, located on chr14:68972452-68972914, is a retrocopy of the parental gene PPP1R1A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PPP1R1A
Full Name protein phosphatase 1 regulatory inhibitor subunit 1A
Also known as -
Coordinate chr11:54198429-54207570
Strand -
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Human Homo sapiens PPP1R1AP1
Chimpanzee Pan troglodytes PPP1R1AP1
Bonobo Pan paniscus PPP1R1AP1
Gorilla Gorilla gorilla PPP1R1AP1
Orangutan Pongo abelii PPP1R1AP1
Gibbon Nomascus leucogenys PPP1R1AP1
Green monkey Chlorocebus sabaeus PPP1R1AP1
Crab-eating macaque Macaca fascicularis PPP1R1AP1
Baboon Papio anubis PPP1R1AP1
Golden snub-nosed monkey Rhinopithecus roxellana PPP1R1AP1
Marmoset Callithrix jacchus PPP1R1AP1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PPP1R1AP1
CCACTTTGGTAATGTCTCCACAGCGACAGAAGATGACAAGGATCACACCCACAATGAGAGAGCTCCAGATGAAGGCTGATGACTGAACATCACTTGGGGCAACAGCAGCAGGGAGAGGCGCCTGAGAAAGCTGCTGAGAACACAGGGACCCAGGAGACCTGCCCACCTGGGATCACAGACACAGAAGAGGAGTCAAGGCTGGGCACCTTTGGGCCAGCACAAGAGCCTGCAGAATCTATCCCCACAACTCAGGAGAGAGTCAGTAAAAAATGCAGCACAAAGGAACCCTCAACCCATGTACCACCACTGGATTCCCATGAAGCTAGCTCGGTTTGAGAGAAGGAGGTATCCTGGAATCACAGCTGCAGTTTGGGAATGCATGAACACTGGATTTGTTTCTTATTTCTTCACTTTTGGGGAAAATCTCTTGTTTTTAAAAAGTGATAAATTTGGTGTTAGGTCA
>NM_001266966.1
gggccggggccggagcggagcggagagggagcgcgCCCGCCCCAGCCCCGAGTCCCGCCGCCTTCCCTCCCGCCGCAGCGCGGGCCCAGCGGCCGCCGCCCCAGCCATGGAGCAAGACAACAGCCCCCGAAAAATCCAGTTCACGGTCCCGCTGCTGGAGCCGCACCTTGACCCCGAGGCggcggagcagATTCGGAGGCGCCGCCCCACCCCTGCCACCCTCGTGCTGACCAGTGACCAGTCATCCCCAGAGATAGATGAAGACCGGATCCCCAACCCACATCTCAAGTCCACTTTGGCAATGTCTCCACGGCAACGGAAGAAGATGACAAGGATCACACCCACAATGAAAGAGCTCCAGATGATGGTTGAGCATCACCTGGGGCAACAGCAGCAAGGAGAGGAGCCTGAGGGGGCCGCTGAGAGCACAGGAACCCAGGAGTCCCGCCCACCTGGGATCCCAGACACAGAAGTGGAGTCAAGGCTGGGCACCTCTGGGACAGCAAAAAAGCCTGCAGAATCCATCCCTAAAACTCAGCAGAGAGGCAGTAAGGAACCCAGCACAAAGGAACCCTCAACCCATATACCACCATTGGATTCCAAGGGAGCCAACTCGGTCTGAGAGAGGAGGAGATACCTTGGGATCAAGACTGCAGTTGGGGAATGCATGGACACCGGATTTGTTTCTTACTCCTTCACTTTTGGGGAAAATCTCTTGTTTTTAAAAAGTGATAAATTTGGTGTTAGGTCCTTGGCACTTTCCTTCTTTCCCAACTTGGAGAATCCTTTCTCCCTGCCTTCTTGCCCTGCCCTCTCTGCAGCCCCCACCCGCCTGCCAAGCTGCCTCTGGGAAGGAAGAACAGAGGAGCTGGGCAGAAGCCTCGAGCAGGGAAGAGTTCTTCCCCTAGCCCTGACTTTACTTTCTGTGGGAAGAGAGATGAGGGTCAGATAGGTGGGAGGACTAACTTCCAGGCTGCCAAGAAGGAAGAAAAGCCCCCGGTTCTCTTTTCTTATTGAGGAACGATCTGACCACCTCACAGGCCTGCCCTGCAGCTGGAACACTCGGCGCTCTAAGGCCTGTGCCGTGTCCAGCTGTGACTGTGCGGTGGGCTCCATCTGCTGGACAAAAGGGGAACTGCACCATGGCACTTGGCCCATGGGATAGAGGGTGTGGTGGGTGTACGGATACCTCCTCGCCCGCCCTCCAAGCCTCAGCTGCCTTCCTTTTGGATTCCCAAGCTTCAGGATGTGTTCCCTCTTCCAGGTGTGGGACCGCTGTCCGTTATTCAACCCGTTAGCAACAGTGGATAGAGAACACAGTGGCTATTAATGAAGAGGCCCGTGCTGGAGACTGGAAGGGTTCCCTTGTCCTAGACACTGAGGACAGATAAGACAAAAACCAAGCATACGAGAAGAAACTGTCTCAGATCTCACGGCCAGGCCTCTCTCCTGCTGCTGTTTTTGATTTTCCTAGGTAGTGGGAGAGAGGAAAGGAGGGAAGGCAAGATTCTTTCCCCCTCCCTGCTgaagcatgtggtacagaggaaagagcagagcctgagaagcgtcaggtcccacttctgccatgcagctactgtgagccctcggggcctcctcctgggcctcagcttgcccagatacatacctaaatgtgtgtatatatatatataaaagggagaacacctcacccagattttg

Publications

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