Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name RPEP4
Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Macaca mulatta
Coordinates chr10:21941861-21943282  UCSC
Strand -
Parental Sequence XM_015110867.2
Parental seq. overlap 996 bp
Parental seq. overlap (%) 39.5%
Genomic Region Intragenic (NF2)
Retrocopy Summary RPEP4, located on chr10:21941861-21943282, is a retrocopy of the parental gene RPE. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RPE
Full Name N/A
Also known as RPE2
Coordinate chr12:97333380-97352138
Strand +
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RPEP4
Bonobo Pan paniscus RPEP5
Gorilla Gorilla gorilla RPEP4
Orangutan Pongo abelii RPEP6
Green monkey Chlorocebus sabaeus RPEP2
Crab-eating macaque Macaca fascicularis RPEP3
Baboon Papio anubis RPEP4
Golden snub-nosed monkey Rhinopithecus roxellana RPEP3
Marmoset Callithrix jacchus RPEP1
Human Homo sapiens Without Homology
Gibbon Nomascus leucogenys Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RPEP4
GGGGACTTGTGGAGTAACTTGCTCTTGGGAACCAGTGTATGGCATCGGGCTGCAAGATTGGCTCGTCCATCCTCAACACTACCTGGCCAATTTAGGGGCCCAGTACCTCTGGATGCTAGACTCTGGGGTCGATTATCTCCACCTGGATGTAATGGATGAACATGTACATGATGGTGTCCAAGCCAGAACAGTGGGTAAAGCCAGTGACTATAAGAGGAGCCAATCAGTACATCTTTCAGCTCGAGGCTACTGAGAACCCAGGGACTTTGATTAAAGACAATTGGGAGAATGGGATGAAGGTTGGCCTTGCCATCAAACCAGGAACCTCAATTCAGTATTTGGCACCGTGGAGTAATCAACTAGATATGGCCTTGGTTATGACAGTGGAACCAGGGTTTGGAGGGCATAAATTCATGGAAGATATGATGCCAAAGGTTCACTGGTTGAGGATCCAGTTCCCATCTTAGGTTATAGAGGTCGCTGGTGGAATAGATCCTGACGCTGTCCATAGGTGTGCAGAGGCAGGAGCTAACATGATTGTGTCTGGCAGTGCTATTGTGAGGAGGCAAGACCCCAGATCTGTGATCAACCTGTTAAGAAATGTTTGCTCAGAAGCTGCTCAGAAACATTCTCTTGATTGATGAAACCATAAGGAGCCCAGTGTTTCTGTTTACGAAATCTCCTTTTTACTGGAAAACAGAAATATCGACTACCAAATCATAATGCAATTGAAGCCATTCTGCTTTTTTGAGCAGTTATTCATTTCGGTGATTATGATTGATTGTACAGAGTATTATAAGAAGTTAGgCAAACAAAAAAAAAGAAGTTAGAAATTGGTGTGTGTGACTACATTTTCAGTGAAGCACTTTATTAGTGAATGAGATACTGTTTTTATTGAGAGCCTTGATTTTTATAAAGAGTAAAAATATGGCTGCATTAAGGTTACAAACAGAAAAGTGTCTTAATGTCTAAGGAGGGCATATTAGCTACACTACAAAAACAATTTTTTTCTGTATTTCTGAAAAGAATTTTGTTGTTTCTCAGCTGTTTTCCAAAAGCAAAGGAAGTTTTCATGTTTTTTTCTATTTTGTGTTATGTGTGATTTGTTTATAT
>XM_015110867.2
ACGGAGAAGGGGCGGGGCCAAAACTGCCCGCCCAATCGGAGTGACGCTCTAGTCTTGCCGGGGGACTCGTGGGGTAACTTGCTCTGGGGAGCCAGCGGTATGGCGTCGGGCTGCAAGATTGGCCCGTCCATCCTCAACAGCGACCTGGCCAATTTAGGGGCCGAGTGCCTCCGGATGCTAGACTCTGGGGCCGATTATCTGCACCTGGATGTAATGGACGGACATGCACATGATGGTGTCCAAGCCAGAACAGTGGGTAAAGCCAATGGCTGTAGCAGGAGCCAATCAGTACACCTTTCATCTCGAGGCTACTGAGAACCCAGGGGCTTTGATTAAAGATATTCGGGAGAATGGAATGAAGGTTGGCCTTGCCATCAAACCAGGAACCTCAGTTGAGTATTTGGCACCATGGGCTAATCAAATAGATATGGCCTTGGTTATGACAGTGGAACCGGGGTTTGGAGGGCAGAAATTCATGGAAGATATGATGCCAAAGGTTCACTGGTTGAGGACCCAGTTCCCATCTTTGGATATAGAGGTCGATGGTGGAGTAGGTCCTGACACTGTCCATAAGTGTGCAGAGGCAGGAGCTAACATGATTGTGTCTGGCAGTGCTATTATGAGGAGTGAAGACCCCAGATCTGTGATCAACCTATTAAGAAATGTTTGCTCAGAAGCTGCTCAGAAACGTTCTCTTGATCGATGAAACCATAAGGAGCCCAATGTTTCTGTTCATGAAATCTCCCTTTTACTGGAAAACAGGAATATTGACTACCAAATCATAATGCAATTGAAGCTGCACTGCTTTTTTGAGCAGTTATTCATTCCAGTGATTAAAACTGATTGTGTAGAATATTCTAAGAGGTTAGAAATTGGTGTGTATAACTATGTTTTTAGTGATGCAGCTTAATGATTAGTGAGTAAGATACTGTTTTTATTGAGAGACTTGATTTTTATAAAGAGTAAAAATACGGCTGTATTAAGGTTACAAACAGAAAAGTGTCTTAATGCCTAAGGAGGGCATATTGACTACACTACAAAAACAAATTTTGTCTGTACTTCTGAAAAGAATTTTGTTGTTTCTCAGCTGTTTTCCAAAAGCAAAGGAAGTCTTTATGGTTTTTTTCTATTTCATGTTATTTGTGGTTTGTTTATAAGTTTGGGTGGGATGGCATACCATATTCTTGGTTCTTAAAATCTATCACTTTTAACCTTACACTTGATGTGTGAAAACTATAAAAACAATGTATGAAACCCAGGGGTTGTAAAATACAAGCATAGATTTTATCAGGGTGTTTTGTCAAAGCAGATTATTCAGTGATTCCTCCCCACCATTCTTAAGGACGTTAAATAATGCTGTTGTGTTAGCTCTGAGTAGAAAggaaaaagtaaaacctctgtttggaagtaatactgggttgaattctgaccgcccctttctagctggacctttaacaaatcacccaatcttttttgtatttctcctaactcatttatacattaaatgtaattataacaactgtggggttgtattgagaattaagaggtaatactatatacctaaagtttccagtactagtcccagaatttagaatatgctcaatacaaagtagATAGCATTATATAAGTTTATatttcatgagttataaagtactttgatatattctcattaaatctgtaaatcacctctataagtaagtggtaataataaagcaggtatttttgtccccatttaaaaaatgaagaaattaatgctcagtagtaggatggtaccctgaaaggatctaggaagtggtagaATTTCTGGTCTGTACTTTTACAAATGGAGCCCTTGGGAGGTCGGTTAGGTAAGAAGCTTTTTACTTAACATTGTCTTATTTCCAGTCTAATTTTACACTGTAGCAGAACCAGATGGCTGAGAATATTCTGGAACTATGGATCTTGACCCCAAGGATATATTATTTTATTCCAAGAAAGATCAGGTAGGCGAAAAGATGACAGGATGCAGAGTCAATCCATAAACTAAGTATTTATAACTGTTTGAATTATAGAGAGTCTAAAAATATGTGTCAGCTATTTCATTCCTGTAAATACTCTTGCTTTGTTATAAATATGGCAAGAAATATCAGTACCAGTATCAATAGACTTCTTGAGGCTACTATAAGTTTTGAGAAATAAGGTTCAAAAAGTAAGAATGCTAACAGTTAAGCTTAGACTAGAGCTTGCTTGGGTTTCTTCCTGCATTACAAGGTAAAAATTTGTTAATGTTTGTTTTTATTTCAGCTTAGGAAAGCTTTGTGCCATGAGTAGGTCGCATTTAATAACAAGCAACACAAGGTATATAGAAATAACTTTAATTAAAAAACTTACATAGAAGATTATAATATCAGACATGACAAAGATTTGAGTTTATTTGCCTGGACAACTTGGGTTTGTCTGGCTTTTGTTTTCTTTTTCTTTAAAAATAAATGTACAGTAAAACTACAAGCAAAAGTT

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