RCPedia: Rtcs

Summary

Retrocopy Name	H2AFZP2	Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr4). Each line represents a retrocopy.
Species	Pongo abelii
Coordinates	chr8:110047270-110047906 UCSC
Strand	-
Parental Sequence	NM_001133846.2
Parental seq. overlap	552 bp
Parental seq. overlap (%)	63.9%
Genomic Region	Intergenic
Retrocopy Summary	H2AFZP2, located on chr8:110047270-110047906, is a retrocopy of the parental gene H2AZ1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	H2AZ1
Full Name	N/A
Also known as	H2AFZ
Coordinate	chr4:98480955-98483149
Strand	-
Gene summary	N/A

Homology

Species	Scientific Name	Retrocopy
Human	Homo sapiens	H2AZP7
Chimpanzee	Pan troglodytes	H2AFZP1
Bonobo	Pan paniscus	LOC100974973P1
Gorilla	Gorilla gorilla	LOC101140733P1
Gibbon	Nomascus leucogenys	LOC100587000P6
Green monkey	Chlorocebus sabaeus	LOC103236032P6
Crab-eating macaque	Macaca fascicularis	LOC102130495P2
Rhesus	Macaca mulatta	H2AFZP2
Baboon	Papio anubis	LOC101021735P3
Golden snub-nosed monkey	Rhinopithecus roxellana	LOC104668848P3
Marmoset	Callithrix jacchus	Without Homology
Mouse lemur	Microcebus murinus	Without Homology
Mouse	Mus musculus	Without Homology
Rat	Rattus norvegicus	Without Homology
Chinese hamster	Cricetulus griseus	Without Homology
Rabbit	Oryctolagus cuniculus	Without Homology
Pig	Sus scrofa	Without Homology
Cow	Bos taurus	Without Homology
Sheep	Ovis aries	Without Homology
Dolphin	Tursiops truncatus	Without Homology
Horse	Equus caballus	Without Homology
Dog	Canis familiaris	Without Homology
Panda	Ailuropoda melanoleuca	Without Homology
Cat	Felis catus	Without Homology
Pale spear-nosed bat	Phyllostomus discolor	Without Homology
Velvety free-tailed bat	Molossus molossus	Without Homology
Greater mouse-eared bat	Myotis myotis	Without Homology
Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
Greater horseshoe bat	Rhinolophus ferrumequinum	Without Homology
Egyptian rousette	Rousettus aegyptiacus	Without Homology
Sloth	Choloepus didactylus	Without Homology
Tasmanian Devil	Sarcophilus harrisii	Without Homology
Opossum	Monodelphis domestica	Without Homology
Platypus	Ornithorhynchus anatinus	Without Homology
Chicken	Gallus gallus	Without Homology
Turkey	Meleagris gallopavo	Without Homology
Zebra Finch	Taeniopygia guttata	Without Homology
Budgerigar	Melopsittacus undulatus	Without Homology
Painted Turtle	Chrysemys picta	Without Homology
Lizard	Anolis Carolinensis	Without Homology
Frog	Xenopus tropicalis	Without Homology
Zebrafish	Danio rerio	Without Homology
Drosophila	Drosophila melanogaster	Without Homology

Expression

Related Sequence

>H2AFZP2
TTCATCAACACCTGAATCCAGGACCACAGCCATGGACATGTGGGCACAACTGCCACTGTGTACCATGCAGCCATCCTGGAGTACACACTGCAAAGGTACTAGAACTGGTAGGAAGGGCATCCAAAGGCTTAAAGGTAAAGCATTACTCTTTGTCACTTGCAACTTGCTGTTCATGGTGATGAAGAATTGGACTATCTTATCAAGATTACAATTACTAATGGTAGTGTCATTGCATACATCCATAAATCTCTGATTAGAAAGAAAACAGAAAACCGTCTAAAAGATGTCTGGATTCATTATTATCCCAGGACTAGAAAACAAAAGTTGTCTGGTGTTGGTGATACCAGTGGACTGTATTTCTATGAAAAACAGTTTTGCCTTGTTGTATTTTATGTGAGCAAGTTGGAAGTTTAATTCATTTTCCAACCAACCATCTTTCTACGTTTGGGTCTTAACCATATTTAATTGTTGCTGTGGCTTCAAAGACCTTATTGATTCCTAAGTAGTGGGTTTTGATTGAGTTTACTTTTTAAAAACTGTTTGGATTTTAATTGTGATACAGAAGTTACAGTAACAAACATATGTTGTACAGACTGTATTTCCACTGTGGTGGGTAAGCTCAAATAAAGGTCATATT

>NM_001133846.2
GCAGTTTGAATCGCGGTGCGACGAAGGAGTAGGTGGTGGGATCTCACCGTGGGTCCGATTAGTCTTTTCTCTGCCTTGCTTGCTTGAGCTTCAGCGGAATTCGAAATGGCTGGCGGTAAGGCTGGAAAGGACTCCGGAAAGGCCAAGACAAAGGCGGTTTCCCGCTCGCAGAGAGCCGGCTTGCAGTTCCCAGTGGGCCGTATTCATCGACACCTGAAATCTAGGACGACCAGTCATGGACGTGTGGGCGCGACTGCCGCTGTGTACAGCGCAGCCATCCTGGAGTACCTCACCGCAGAGGTACTTGAACTGGCAGGAAATGCATCAAAAGACTTAAAGGTAAAGCGTATTACCCCTCGTCACTTGCAACTTGCTATTCGTGGAGATGAAGAATTGGATTCTCTCATCAAGGCTACAATTGCTGGTGGTGGTGTCATTCCACACATCCACAAATCTCTGATTGGAAAGAAAGGACAACAGAAGACTGTCTAAAGGATGCCTGGATTCCTTATTATCTCAGGACTCTAAATACTCTAACAGCTGTCCAGTGTTGGTGATTCCAGTGGACTGTATCTCTGTGAAAAACACGATTTTGCCTTTTTGTAATTCTATTTGAGCAAGTTGGAAGTTTAATTAGCTTTCCAACCAACCAAATTTCTGCATTCGAGTCTTAACCATATTTAAGTGTTACTGTGGCTTCAAAGAAGCTATTGATTCTGAAGTAGTGGGTTTTGATTGAGTTGACTGTTTTTAAAAAACTGTTTGGATTTTAATTGTGATGCAGAAGTTATAGTAACAAACATTTGGTTTTGTACAGACATTATTTCCACTCTGGTGGATAAGCTCAATAAAGGTCATATCCC

>NM_001133846.2 

GCAGTTTGAATCGCGGTGCGACGAAGGAGTAGGTGGTGGGATCTCACCGTGGGTCCGATTAGTCTTTTCTCTGCCTTGCTTGCTTGAGCTTCAGCGGAATTCGAAATGGCTGGCGGTAAGGCTGGAAAGGACTCCGGAAAGGCCAAGACAAAGGCGGTTTCCCGCTCGCAGAGAGCCGGCTTGCAGTTCCCAGTGGGCCGTATTCATCGACACCTGAAATCTAGGACGACCAGTCATGGACGTGTGGGCGCGACTGCCGCTGTGTACAGCGCAGCCATCCTGGAGTACCTCACCGCAGAGGTACTTGAACTGGCAGGAAATGCATCAAAAGACTTAAAGGTAAAGCGTATTACCCCTCGTCACTTGCAACTTGCTATTCGTGGAGATGAAGAATTGGATTCTCTCATCAAGGCTACAATTGCTGGTGGTGGTGTCATTCCACACATCCACAAATCTCTGATTGGAAAGAAAGGACAACAGAAGACTGTCTAAAGGATGCCTGGATTCCTTATTATCTCAGGACTCTAAATACTCTAACAGCTGTCCAGTGTTGGTGATTCCAGTGGACTGTATCTCTGTGAAAAACACGATTTTGCCTTTTTGTAATTCTATTTGAGCAAGTTGGAAGTTTAATTAGCTTTCCAACCAACCAAATTTCTGCATTCGAGTCTTAACCATATTTAAGTGTTACTGTGGCTTCAAAGAAGCTATTGATTCTGAAGTAGTGGGTTTTGATTGAGTTGACTGTTTTTAAAAAACTGTTTGGATTTTAATTGTGATGCAGAAGTTATAGTAACAAACATTTGGTTTTGTACAGACATTATTTCCACTCTGGTGGATAAGCTCAATAAAGGTCATATCCC

Publications

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