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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name Chmp2aP1
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Mus musculus
Coordinates chr13:77083220-77084009  UCSC
Strand +
Parental Sequence NM_001360731.1
Parental seq. overlap 735 bp
Parental seq. overlap (%) 79%
Genomic Region Intragenic (Mctp1)
Retrocopy Summary Chmp2aP1, located on chr13:77083220-77084009, is a retrocopy of the parental gene Chmp2a. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Chmp2a
Full Name charged multivesicular body protein 2A
Also known as 1500016L11Rik|mVps2
Coordinate chr7:12765933-12768704
Strand -
Gene summary Predicted to enable phosphatidylcholine binding activity and protein domain specific binding activity. Predicted to be involved in several processes, including mitotic nuclear division; protein-containing complex assembly; and regulation of cell cycle process. Located in cytosol. Is expressed in several structures, including central nervous system; ganglia; gut; lower urinary tract; and olfactory epithelium. Orthologous to human CHMP2A (charged multivesicular body protein 2A). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>Chmp2aP1
TGTTCTCTCTGCTCTACTACTTCTGACGGTTGTCCCAGATGTGCTGGTGGAGTCTTACCACCATGGACCTGTTGTTTGGGCACCAGAAGATGCCAGAGGAACTACTTCAGGAAAACCAGGGGGCCCTGAACCAAGCTATGAGAGAGCTGGACATGGAATGACAGAAACTAGAGacccaggaaaataaaataattgcagACATCAAAAAGATGGCAAAGCAAGGCCAGGTGGATGCTGTTCAAATCATGGCAAAAGACCTGGTGCACACCCAGAGATATGTGCACAAGTTTGTGTTGATGCAGGCCAACATCCAGGCTGTGTCTCTTAAGATACAGACTCTAAAATCCAACAACTCAATGTCACAAGCCATGAAGGGTGTTACTAAGGCCATGGGCACCATGAACAGACAGCTGAAATTACCCCAGATCCAGAAGATCATGATGGAGTTTGAACGGTAGGCAGAGATCATGGACATGAAAGAAGAAATGATGAATGACACAATTGATGATGCCATGGGtgatgaggaagatgaagaggagagtGATGCTATTGTGTCCCAGGTACTAGATGAGGTGGGACTGAGCCTCACAGATGAGCTGTCAAACCTTCCCTCCACTGGAGGCTCACTCAGTGTGGCTGCTGGTGGAAAGAAAGCAGAGGCTACAGCCTCAGCCCTGGCTGATGCTGATGCAGACCTGGAAGAGAGGCTCAAGAACCTTCCCAAGGACTGAAAACGCCCCACCTGGACTCAAAGCATCCTGTCCCCCCTTTAATAAAGAAAtttggacac
>NM_001360731.1
GTGTGACGTCAGGTCGCTTAATCCGGAAACGGCGGCCGCAGCAGGGGCTACCGAACCGAGGGGTTGTCGTTGGTGGAGTCTCAAGGCTTCGGAGGGGTAGAGGCGTGACCCGGAAGCGGAAACCCATCGTTCTCTCGGCTCCGCTAGTTCTGACGGTTGTCCCAGACCTGCTGGTGGAGTCTTACCACCATGGACCTGTTGTTTGGGCGCCGGAAGACGCCAGAGGAACTACTTCGGCAAAACCAGAGGGCCCTGAACCGAGCCATGAGAGAACTGGACAGGGAACGACAGAAACTAGAAAcccaggaaaagaaaatcattgcgGACATCAAAAAGATGGCAAAGCAAGGCCAGATGGATGCTGTTCGAATCATGGCAAAAGACCTGGTGCGTACCCGGAGATATGTACGCAAGTTTGTGTTGATGCGGGCCAACATCCAAGCTGTGTCCCTCAAGATACAGACTCTAAAATCCAACAACTCAATGGCACAAGCCATGAAGGGTGTTACTAAGGCCATGGGCACTATGAACAGACAGCTGAAATTACCCCAGATCCAGAAGATCATGATGGAGTTTGAACGGCAGGCAGAGATCATGGACATGAAGGAAGAAATGATGAATGACGCAATTGATGATGCCATGGGtgatgaggaagatgaagaggagaggTtGATGCTGTTGTGTCCCAGGTCCTGGATGAGCTGGGACTGAGCCTCACAGATGAGCTGTCAAACCTTCCCTCCACTGGAGGCTCACTCAGTGTGGCAGCTGGTGGGAAGAAAGCAGAGGCCACAGCCTCAGCCCTGGCTGATGCTGATGCAGACCTGGAAGAGAGGCTCAAGAACCTTCGCAGGGACTGAAAACACCCCACCCCAACTCAGTGCATCCTGTCCCCCTGTAATAAAGAAATTTGGACACTAATTTACCAA

Publications

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