Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name HnrnpkP3
Plot displaying the genomic locations of a retrocopy (in chr13) and its respective parental gene (in chr13). Each line represents a retrocopy.
Species Mus musculus
Coordinates chr13:91409049-91410541  UCSC
Strand -
Parental Sequence NM_001360494.1
Parental seq. overlap 1427 bp
Parental seq. overlap (%) 52.7%
Genomic Region Intergenic
Retrocopy Summary HnrnpkP3, located on chr13:91409049-91410541, is a retrocopy of the parental gene Hnrnpk. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Hnrnpk
Full Name heterogeneous nuclear ribonucleoprotein K
Also known as Hnrpk|KBBP|NOVA
Coordinate chr13:58538946-58551157
Strand -
Gene summary The protein encoded by this gene is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex, and is a poly-cytosine binding protein (PCBP). It is found in multiple subcellular compartments including the nucleus, cytoplasm and mitochondria. This gene product is thought to interact with RNA, DNA, and protein, and is involved in multiple cellular processes, including transcription, chromatin remodeling, DNA damage response, signal transduction, mRNA splicing, export, and translation. Multiple transcript variants and protein isoforms exist, with some isoforms containing a unique C-terminus. There are four pseudogenes of this gene, found on chromosomes 2, 3, 7 and 13. [provided by RefSeq, Aug 2014]

Homology

Species Scientific Name Retrocopy
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>HnrnpkP3
AGTACCAACATTATAAAGGAAGTGACTTTGATTGCGAGTTGAGACTGTTGATTCATCAGAGTCTGGCAGGAGGAATAATTGGTGTTAAAGGTGCTAAAATCAAAGAACTTCGAGAAAACACTCAGACAACAATCAAGCTTTTCCAGGAGTGCTGCCCTCACTCTACTGACAGAGTTGTTCTTATTGGAGGAAAACCTGATAGGGTTGTAGAATGCATTAAGATCATCCTTCACCTTATATCTGAGTCTCCTATCAAAGGACGTGCACAACCGTATGATCCCAACTTTTATGATGAGACCTATGATTATGGTGGTTTTACAATGATGTTTGATGACCGCTGAGGATGACCTGTGGGATTCCCCATGAGGGGAAGAGGTGGTTTTGACAGAATGCCTCCTGGTCAGGGTGGGCGTCCTATGCCTCCTTCTAGAAGAGATTATGATGATATGAGCCCTTGTCGAggacctccaccacctcctcctggtCGAGGTGGCCGGGGTGGCAGCAGAGCCCGgaatcctcttcttcctccaccaccacccagagGGGGAGATCTAATGGCTTATGACAGAAGAGGAAGGCCTGGAGACCGCTATGATGGCATGGTTGGGTTCAGTGCTGATGAAACTTGGGACTCTGCAATTGACACATGGAGCCCATCAGAATGGCAAATGGCTTATGAACCACAGGGTGGTTCTGGATATGACTATTCTTATGCAGGGGGGTCGTGGCTCATATGGTGATCTTGGCGGACCTATTATCACTATACAAGTAACTATTCCCAAAGATTTGGCTGGATCTATTATTGCCAAAGGTGGTCAGCGGATTAAACAAATTTGTCATGAATCTGGAGCATCAATCAAAATTGATGAACCTTTAGATGGATCTGAAGATCGGATCATTACCATTACAGGAACACAGGGCCAGATACAGAATACACAGTATTTGCTGCAGAACAGTGTGAAGCAGTATGCAGATGTTGAAGGATTCTAATgcaagatattttttcttttttataatgtgAAGCAGTATTCTGGAAAGTTTTTCTAAGACTAGTGAAGAACTGAAGGAGtcctgcatctaatctgcttctgtttaaaaagccaacattcctcTGCTTCATAGGTGTTCTGCATTTGAGGTGTAGTGAAATCTTTGCTGTTCACCAGATGTCATGTTTTAGTTCCTTACAaacagggttggggggagggcatgCAAAAACTAACATTGAAATTTTGAAACAGCAGCAGAGTGagtgacttttattttttgttaattgttggtggtttaaaaaaaattccccccATGTAATTATTGTGAACACCTTGCTTTGTGGTCACTGTAACATTGGGGGGTGGGACAGGGAGGAAAGTAATAGTCCACATGTGCCTGGTATTTGTTCAGAGCAGTGTGCAGAATGTAATGCTCTTTTGTAAGAaatgttttatgattttaaaa
>NM_001360494.1
CAGTGACCGACCGTCGGAGGCGGCGCGGCCGGGAGGCAACGGCGGACTCGCGCGATTGGTGGATCCATTTAATTCAAGAAAATGGAGACCGAACAGCCAGAAGAAACCTTCCCCAACACCGAAACCAATGGTGAATTTGGTAAACGCCCTGCAGAAGATATGGAAGAGGAGCAAGCCTTTAAAAGATCTAGAAATACTGATGAGATGGTTGAATTGCGCATTTTGCTTCAGAGCAAGAATGCTGGAGCAGTGATTGGAAAAGGAGGCAAGAATATTAAGGCTCTCCGTACAGACTACAATGCCAGTGTTTCAGTCCCAGACAGCAGTGGCCCCGAGCGCATACTGAGTATCAGTGCTGATATTGAGACGATTGGAGAAATTCTGAAGAAAATCATCCCTACCTTGGAAGAGTACCAACATTATAAAGGAAGTGACTTTGATTGCGAGTTGAGACTGTTGATTCATCAGAGTCTGGCAGGAGGAATAATTGGTGTTAAAGGTGCTAAAATCAAAGAACTTCGAGAAAACACTCAGACAACAATCAAGCTTTTCCAGGAGTGCTGCCCTCACTCTACTGACAGAGTTGTTCTTATTGGAGGAAAACCTGATAGGGTTGTAGAATGCATCAAGATCATCCTTGACCTTATATCTGAGTCTCCCATCAAAGGACGTGCACAACCTTATGATCCCAACTTTTATGATGAGACCTATGATTATGGTGGTTTTACAATGATGTTTGATGACCGCCGAGGACGACCTGTGGGATTCCCCATGAGGGGAAGAGGTGGTTTTGACAGAATGCCTCCTGGTCGGGGTGGGCGTCCCATGCCTCCTTCTAGAAGAGATTATGATGATATGAGCCCTCGTCGAggacctccaccaccaccacctggtcgAGGTGGCCGGGGTGGCAGCAGAGCCCGgaatctgcctcttcctcctccaccaccacccagagGGGGAGATCTAATGGCTTATGACAGAAGAGGAAGGCCTGGAGACCGCTATGATGGCATGGTTGGGTTCAGTGCTGATGAAACTTGGGATTCTGCAATTGACACATGGAGCCCATCAGAATGGCAAATGGCTTATGAACCACAGggtGGTTCTGGATATGACTATTCTTATGCAGGGGGCCGTGGCTCATATGGTGATCTTGGCGGACCTATTATCACTACACAAGTAACTATTCCCAAAGATTTGGCTGGATCTATTATTGGCAAAGGTGGTCAGCGGATTAAACAAATTCGTCATGAATCTGGAGCATCAATCAAAATTGATGAACCTTTAGAAGGATCTGAAGATCGGATCATTACCATTACAGGAACACAGGACCAGATACAGAACGCACAGTATTTGCTGCAGAACAGtgTGAAGCAGTATGCAGATGTTGAAGGATTCTAATgcaagatattttttcttttttatagtgtGAAGCAGTATTCTGGAAAGTTTTTCTAAGACTAGTGAAGAACTGAAGGAGtcctgcatctttttttttttatctgcttctgtttaaaaagccaacattcctcTGCTTCATAGGTGTTCTGCATTTGAGGTGTAGTGAAATCTTTGCTGTTCACCAGATGTAATGTTTTAGTTCCTTACAaacagggttggggggagggcatgCAAAAACTAACATTGAAATTTTGAAACAGCAGCAGAGTGagtgacttttattttttgttcattgttggtggttttaaaaaaaattccccccATGTAATTATTGTGAACACCTTACTTTGTGGTCACTGTAACATTGGGGGGTGGGACAGGGAGGAAAGTAATAGTCCACATGTCCCTGGCATTTGTTCAGAGCAGTGTGCAGAATGTAATGCTCTTTTGTAAGAAAcgttttatgatttttaaaataaatttagtgaATCTatttttggtggtcttttttttttttaagacaatttCAAATGGTGGTTGAATTTTCCAGCCCACCCCTAAACTAAACACTAAGTTTGATTTTCAGCAGCTCCTCTGTTGGATATAAGTGCACCTCTTGGACATAGACAAAATACATTGGCAAACTCAGTTTGGGTGACTTCTTAATGGTTGGAAAGACTTGGCTTGATAAATTTCCATCACATATTCATGCTTATAATAAgcttgggattttgtttgtttttgcaaatgTTTGCCACTACTTTTCAACAGTTTTCTGTTAGTTGTGGAGAACTGCGGTGGGGAGCAATACTACAAGAGTTACGCATCTTAAGTATATGCCAGAAGCCTGATGGGCAATGAGCTTTATTAACCAGAGTAAACTTGGTTATGGAAGTGGCTGATGCTGAATAAATCCTGGTTATTTTTGTTAGATAATTTCTCACCTATAGACTTAAAGCTGTCAACCTGCTAGTGTCTTGTTAGTTGAActttgtaaaaatatatatatatacttgtttttccattgtatgcacaatgaaagaaaaaagatgtaCCATTTCTCTGTTGTGTGTTGAATTATGTAGGAAATGTTTGTGAACGATtcgaaaaaaatggaaaaagttcCTGTGGATGTTTTGTGTAGTAACTTGGCATCTGTATTGATAGTTCAAAATCCACATCTAAATAAAACTTCCATGATGTTAGTTATGACGTGTGCCCAATTTGAAAAGGGGTTGATTAATACATGTAAAGTTTGTTGAAGTGTTCCTCTTGTAAGGAAATACAGTAATCTTAAATta

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