Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name Zfp91P1
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Plot displaying the genomic locations of a retrocopy (in chr17) and its respective parental gene (in chr19). Each line represents a retrocopy.
Species Mus musculus
Coordinates chr17:15755257-15756742  UCSC
Strand -
Parental Sequence NM_053009.3
Parental seq. overlap 1270 bp
Parental seq. overlap (%) 22.6%
Genomic Region Intergenic
Retrocopy Summary Zfp91P1, located on chr17:15755257-15756742, is a retrocopy of the parental gene Zfp91. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Zfp91
Full Name zinc finger protein 91
Also known as 9130014I08Rik|A530054C17Rik|Pzf|Zfp-91
Coordinate chr19:12744303-12773487
Strand -
Gene summary The protein encoded by this gene is a member of the zinc finger family of proteins. The gene product contains C2H2-type domains, which are the classical zinc finger domains found in numerous nucleic acid-binding proteins. The homologous human protein has been shown to function as a regulator of the non-canonical NF-kappaB pathway in lymphotoxin-beta receptor signaling. A read-through transcript variant composed of Zfp91 and the downstream Cntf gene sequence has been identified, but it is thought to be non-coding. Read-through transcription of Zfp91 and Cntf has been observed in both human and mouse. A Zfp91-related pseudogene has also been identified on chromosome 17. [provided by RefSeq, Oct 2010]

Homology

Species Scientific Name Retrocopy
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>Zfp91P1
CGTCTCCTGCTCAGGACAAGAAGAGTCGGTGACTCCagtgtatagATCCGGAGGAAGCGAAAGATGATTCTGTCCTCCCTCAGGAAGCTCCCATTAATGCAACTAGACCTAGCAGGAGCTGGCACAGTAGAAGCAGCacctctatctctttctttcaagacagtgAGAACACTCAGAACTCTAAGTCCAAGACTGGTTCTTTGTAACTTATCTGCAAGACAGAACCAATTACAGATCAACTTTCTAATGACGTTCCAGAAGAGCACCAGTCTCCCGGTGGCGTTAGTAGtgatgagaaagaggaggaggtagaagaaaTGTTAATCAGGGAAGAGGAAATATCATTCGAAGACGACCCAAGAGATGAGACTTACAAGCCCCACCTTGAAAGGGAAACCCCACAGCCACAGAGCAAATCGGGGAAGAAGAGGACGAAATTAGGGAAGATGAGGAGCCtcttaggaagagaggaagaaggcgAAAAGATGACAAAAGTCCACGGTtacccaaaagaagaaaaaagccaATTCAGTATGTCTGTTGTGAGATGGGAGGATGTGGGACTGTTCTTGCTCACCCTCGCTGTTTGCAGCACCACATTAAATACTAGCAGTTGCTGGGGGGCGGGAAAATGTCCCCATCTCTCCTATGGACGACTCTTTAAGCTCCAGAAACAACATTTGCGACTTGCAAAGCCATGTCAGACAGACCAGACCTGAGGAATTATATTTGTGAATACTGTGCTTGGGCCTTCAAGAGTTCCCACAATCTGGCAGTACACCGGATGATTCATACTGGCGAGAAGCCATTACTATGTGAGATCTGTGCATTTACTTGTCGACAAAAAGCATCTCTTAGTTGGCACATGAAGAAACGTGATGCAGACTCCTTGCTACCAGTTTTCTTGCAATatctgtggggggaaaaaaatgagaaggaCAGTGTAGTGGCATACAAAGCAAAATGCCACCCTAAGGTGCTGATTGCACAAGTTCTGGCAGCCAATGCGGGCGCTCTCATCACCAGCACAGATATCTTGGGCACTAACCCAGAGGCCCTGACACAACCTGAAGATGGTCAggggcttcctcttcttcctgagcCCTTGGGAAACTCAACAGCTGGAGAGTGCCTACTGCTAGAAGCTGAAGGGATGTCAAAGTCACACTGCAGTGGGACAGAACGGGTGAGCCTTATGGCTGACGGGAAGATCTCTGTGGGAAGTGGCAGCAGTGGGGGCACTGAAGGGCTGGTCATGAACTCGGATATACTTGGTGCTACCATAGAGGTTCTGATTGAAGATACAGACTCTACTGGACCCTAGTGCAAAGGAAGACTTTGGGCACTGGGATAGTGCAGGCTTtctaattaaaagataaaaaggacaaaaaaat
>NM_053009.3
ATTTTTTCAGAGACTTTCATCCGGCAACGGACAGggccttttttttcttaaaggagaAGCTGCAACTCAAATAATTTACCACTTCTCCCCTCGAGAGCTGGCGGCGCTGGGGACAGAAAGGCCAGAGCAGGAAGGTGGGGGTCTGGGTGGAGGCGGGATAACGTCCAGGCTACTTCTTAGGCTAGTAAGAACCCTTGAGGGGACAGCGGCGCCTCCGGGAGGCAGGTGCGCGCGCAGCCGGCAGGGGGGTGCGCGCGCGGCTGAGAACGGTGCGTTTTGTCCTCGCCTCCGCCCTCGCCAGCCCTGCCCCTCCCACCGCCCCTAGCTTGAGCCGAACTCCAAAGTGGGGGGGGAGAAAGGTCACTTTGGGATTGTCGCGAGACGCAGCCGTTTAACGGTGAGAACGGGCGCGCGGGCAAGGAAACCTCGCGCTCTCCCTCGGAGCCGTTTCCTGATTGGttggaggaaggggtgggggagggcaccGAGTGCGCTGCTGCGTGTGAGACCGCGAGGGGCCGGGCCAGGGGGGCCGATCCTCCCCTCCGATTGGCCCGCTGCGTGTCCGTCCGGGTGCGCGCGTGCGCGCCGCCGGCGGTCGCTGGCTTGAGTGGCAGGGGGCGGGTGGGGGGGGGCGCCCTCGGAACGGGCGGAGGGGCGGGGGGGAGAGAGGCGCTCCGGAGTGAGGGAGCCGGACGCTCCGGGAGccgaggggggcggggggagctgCGCCGCGGGCGCCGCCGCCTCCACCGCCTGGGACGCAGGGGTGGGGGACGGACGAGCCCCGATGCCGGGGGAGACGGAGGAGCCGCGATCCCCGGAGCAGCAGGACCAGGAAGGGGGCCCAGCAGCGGCGGCCGACGCGGCTTCGGAGGAGCTCCGGCCCGGCGCGGCGGCGGCGCCGGCGGCGCCTGCAGAGACCGCGAGCAGCCGCGTGCTGAGGGGAGGTCGGGACCGCGGCCGGACCGCtgcggccgccgccgccgccgctgccgctgtGTCCCGCCGGAGAAAGGCCGAGTATCCCCGCCGGCGGAGGAGCAGCCCCAGCAACAGGCCTCCCGACGGCCCAGGGCATCAGCCCGCGGCCGCGAAGCCCCCGTCTCCTGCTCAGGGCAAGAAGAGTCCGCGACTCCAgtgtATAGAAAAACTAACAACTGATAAAGATcccaaggaagagaaagaagatgatTCTGTCCTCCCTCAGGAAGTTTCCATTACTACAACTAGAGCTAGCCGGAGCTGGCGCAGTAGTAGCAGGACCTCTATCTCTCGCCTTCGAGACAGTGAGAATACTCGGAGCTCTAGGTCCAAGACTGGCTCCTTGCAACTCGTCTGCAAGACAGAACCAATTACTGATCAACTTGATTATGaTGTTCCAGAAGAACATCAGTCTCCCGGTGGCATTAGtagtgatgaggaagaggaggaggaagaagaaatgttAATCAGTGAAGAGGAAATACCATTCAAAGATGACCCAAGAGATGAGACTTACAAGCCCCACCTTGAAAGgGAAACCCCAAAGCCACGGAGAAAATCAGGGaaggtgaaagaagagaaagaaaagaaagaaattaaagtggaAGTAGAAGTAGAGGtgaaagaagaagagaatgaaattagggaagaTGAGGAGCCTCCCAGGAAGAGAGGGAGAAGGCGAAAAGATGACAAAAGTCCGCGGTTACCCAAAAGGAGAAAAAAGCCTCCAATCCAATATGTCCGTTGTGAGATGGAAGGATGTGGAACTGTTCTTGCTCACCCTCGCTATTTGCAGCACCACATTAAATACCAgcatttgctgaaaaaaaaatatgtatgtccCCACCCCTCCTGTGGGCGACTCTTCAGGCTCCAGAAACAACTTCTGCGGCATGCAAAGCATCATACAGaCCAGAGGGATTATATCTGTGAATATTGTGCTCGGGCCTTCAAGAGTTCCCACAATCTGGCAGTACACCGGATGATTCATACGGGCGAGAAGCCATTACAATGTGAGATCTGTGGATTTACTTGTCGACAAAAAGCATCTCTTAATTGGCACATGAAGAAACATGATGCAGACTCCTTCTACCAGTTTTCTTGCAATATCTGTGGCAAAAAATTTGAGAAGAAGGACAGTGTAGTGGCACACAAAGCAAAAAGCCACCCTGAGGTGCTGATTGCAGAAGCTCTGGCAGCCAATGCGGGCGCCCTCATCACCAGCACAGATATCTTGGGCACTAACCCAGAGCCCCTGACACAGCCTGCAGATGGTCAggggcttcctcttcttcctgagcCCTTGGGAAACTCAACAGCTGGAGAGTGCCTACTGCTAGAAGCTGAAGGGATGTCAAAGTCATACTGCAGTGGGACAGAACGGGTGAGCCTTATGGCTGACGGGAAGATCTTTGTGGGAAGTGGCAGCAGTGGGGGCACTGAAGGGCTGGTCATGAACTCGGATATACTCGGTGCTACCACAGAGGTTCTGATTGAAGATACAGACTCTACTGGACCCTAGTGCAAAGGAAGACTTTGGGCACTGGGACAGTGCAGACTTtgtatttaaaagataaaaaggacaaaaaaaatttaaagcatttaaaaatctaGTAAAATAACTGAAGGGCCTGCTCTTTGCATTGTggatcacaacacacacacacaccatccccaTTCCCTGAACTCCCCTTCCTCATCCTTAAAATATTGATGTAGCCTTTACCAGAAAGGTTGATGAAAAAGCAGCAACATGCTAGGTTCCAGCCAGCAGCAGACTTCCTGCTCATTGGCAAATCTCCTTTTTCTCAGCCTATAACTCTGATGTGCTCTGGATCAGCTTTGAACTCATAATAGTATATTACTATCATCTAAATCTTTTCTCCTCTACTACTGCCCTATGGCTCTGGCTTCTTCCCACTGCAACAACCAACACTTACCCTCAAATATTATATAATTCTATTTTCCGGAGGCTGGCAGCTTGACTTGGCACTTTAGGGCTCCTTGGCAGGATGCTGTTAAAACAGCACACATCTCTCACCCCTCTTCCATTACTCACTGGGTTTGGGGAAGGAAGGATACATGGGGACCACCTCCCTCCCTTTCAATGGATCCCAGCACCTCAGTTCCCCCCACTCCTGAACCTCCATAATGCTCTTAATGGTGCTCACTTGCTTGGAAGCAGGCTCCCAAGAGAGGGGACTGACCTCTGTTTCTGGCTGAAAGATAGGGCTCTGTGTCAGTGAGAAAAGTCCCAGGCTAATGGCAGAAATTTGCACTTTGaacatgtgtgttttgtgttgtgGAACCTGAGATTCCTTATTTATTAATGGAAAGTctgattttttgggggggagggtcttTGTTGCTATGTTTTGTGGGGCTGGGAGAGTAGATTATTCTGACATGGGATCCTTCCTACAAGAGGTACTTTGAAGGCAAGGCTTAGAGTTGAAGAAGCACAGCCAGCCTCTAAAATCATAGTTCTCCAGTGGCCTTTAAAGTAAGCTGGTCCCCAGCACTAACAGAATCACTACAATAGCCTAGTGCTTTTTTGGAAGCCTTAGGGAAGTTTGATAGGTTTGTGGTAACTAGTGTGCTCTTTGAGATTTTTAAGAGCATTTGAGATACAAGAATTTTGAGGGGATGAGGAATGTTGGTCAAGGTCTAAATCACACATAaaaaattttcttctgtgaattTATCTTCTTTGCATATATATCCCTGCTGGCcccttgttttgattttgttattgGTCATTCCAGCTCTCAGTGGAAGACCGGACCCTGTCATTCATGAAGGAACACAATCTAAAAGTTCTAGAGATTTGGTTAAGAGTAAACTCTTCTGTCTTATCTCCTCTTTAGAAGAGACAAAGCTTCAatagacaaaaacaaaagtaaaaatctATACGATAATGTTTTTTGGCTTTCCCCAGAATTATCTGttttcctctgagtagagattttAATGCCCTGTGGCATTAAAATTACTGTCACTGGGAGACACGGATCATATTTTTACATGCTTCTACCTCTCAAAAGACTAAAACCCTAATTCAGCTCATTTTTTGAAAATTAGGAGTGCAGTTCTTCCCTGTGTACTTCAGAATCAGCCATTGAAGACTGGGCCAGTTGTTGTCAGCAACACATGATGACTATTGGGAAAAATAAGAGTTTGAGAACAAAATAAGGAACAGCTTGTTTTTCACAAACACTAAAACTGTGGAGTTTATCAAattttctctgcttgatttttttttccccccaaaaggAGAATAGCAAAATGTCATCTCTGAAAGACGCTTACTATACACCCACCTATGTCGGTGGTTGGGAtgccagggagagggaggaagacacCTACAGGAACAATCTTAAACACATTATTGTTTCCTCTAGAGTGTTGCAGACTTAGCCACCCCTCCATGTGAGGGGAGAAAAGGCATGAAGACAGGCTTTTCTGCCCTGCAGAGTTGCAGTTGACCTTGGTACATTGCATAGATTTGAAAACACTTTAAGAGGAATTAAAAATGGATCTGCAGCAAACTTTGCTCCTCTTGACGCTGTTTATCTAGTATCTGTGTCCTACACTTACCCTTTGTTTTTCACATTTAGAATGTCTCCAATAAATTAGATAGAGCCACCCACAGAAAAACAAACTGCATTGAAAACATCTCACTTTTCTGGGATGGGGAAAAATATGTTCTTTTCTGTACTTCGCTCTCCTCCCCATAAAAGCAACTAGTTCTAAAACTTAGAAACTTCCTGTCCTCtcatggggttggggtggggctgaAAGGGGGCTCGGTCATCTTAGCTGCTCTCTGTTGGCAATAAGTTTTTTTAGCAGTTTGCAATAAATTTTTCATGAACTTCCTATTCCTTTTGAGAGCTAGTGCTAGTATAATAAAAGTGTATGAGCAAACTAAGCCCctacccttttcttttttcccatgcCAGTCATTTAATTGTCCTTCGAAGGAGTCCTTTTAGTTTTGAAAATAGTTAATTCATACTGATGGTTTGTTATCTTTTAAGTCATACCTCCATCTTCAATTGGCAATTCTAAATTCTTAGGTATATAGTTATGATAATTACTTGGTATTTCTGGGAGTTGTGTACCCTCCTTGCTTGCATTGCTAGCGTATTTTGCATAATTAGACCCTAACACATTTTACAGGGTTTAGTCAGACACTGGCTGGGAGTCCTGGGAATGAGCAGAGAAAACATCAGCATAGAGCACTTGGACCTCCCTTGTACCTGTTCAGAGGAAGAAAATCAACTAACTATATACCAACAACCTAAGTGAGGTCTTACAGCCTTGCTGCAGGGCTAgtttcctgcctttctttctatcaATTTTCCAGTATACTCAAGAAAATCGGGAAATTGTAATGGGGCAGTTATATCTCCTGAGACTTTTTGCCTGTTGAAATGTGCAGGACCCTTTTCCTGTGATGAGAGATAGCTGGTTACTTGATCTAGGTTTAAAAgttatgtaaaagaaaaaaattataataaaagggaTACTTTGCTTTTAAAATCTTGTTTCCTTTTAATCTAGGTAATCATTTCAAAATAAGtatgtaaagaagaaaaataaaagttgtcTTCCTGGAA

Publications

PMID - Link Title
No publications available for this retrocopy