Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PrkacaP1
Plot displaying the genomic locations of a retrocopy (in chrX) and its respective parental gene (in chr8). Each line represents a retrocopy.
Species Mus musculus
Coordinates chrX:160266775-160269506  UCSC
Strand -
Parental Sequence NM_001277898.1
Parental seq. overlap 1740 bp
Parental seq. overlap (%) 76.8%
Genomic Region Intergenic
Retrocopy Summary PrkacaP1, located on chrX:160266775-160269506, is a retrocopy of the parental gene Prkaca. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Prkaca
Full Name protein kinase, cAMP dependent, catalytic, alpha
Also known as PKCD|Pkaca
Coordinate chr8:84699607-84723073
Strand +
Gene summary This gene encodes a member of the serine/threonine protein kinase family. The holoenzyme, protein kinase A (also known as cyclic-AMP dependent protein kinase), mediates cellular response to changes in cyclic-AMP levels. This gene encodes the alpha catalytic subunit of protein kinase A. Protein kinase A-mediated signaling is transduced via phosphorylation of target proteins, and is important for many cellular functions, including mammalian sperm maturation and motility. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been defined on the X chromosome. [provided by RefSeq, Apr 2013]

Homology

Species Scientific Name Retrocopy
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PrkacaP1
GCCCTGAGAAAGACTTGAGTGATGCCTTCCAGCTCCAATGATGTGAAAGATTTCCTAGCCAACGCCAAGGAAGattttgctggaaaaaaaaatgggagactCCTCAGAATACAGCCCAGTAGGATCAGTTTGATAGAATCAAGACCCTTGGCACCGGCTCCTTTGGGCAAGTGATGCTTGTGAAACACAAGGAGAGTGGGAACCATTATGTCATGAAGATCTTGGACAAGCAGAAGGTGGTGAAGCTGATCAAACACACTCTGAATGAGAAGTGCATCCTGCAGGCCGTCAACTTCTCCTTCCTGGTCAAACTTGAATTCTCCTTCAAGGATAACTCAAACTTGTACATGGTCATGGAGTATGTGGCTGGTGGAGAGATGTTCTCCCACTTATGGTGGATCAGGAGGTTCAGCAATGTCCATTTCTACAATGCACACAGGTCGTCCTGACCTTTGAGCATCTGCACTCCCTGGACCTCATCTATGGGGACCTGAAGCCCAAGGACCTTCTCATCAACCATCAGAGCTATATTCAGGTGAAAGACTTTGGCTTTGCCAAGCATGTGAAAGGTCATATTTGGATCTTGTGTGGGACCCTGGAGTACTTACCCCTTGAGATTATCCTGAGCAAAGGCTGCAACAAGGCTGTGGACTGGTGGGCTCTCGGGGTCCTCATCTACAAGATGGCTGCTGGTTACCCGCCCTTCTTTGCTGACCAGCCTATCCAGATCTATGAGAAAATCGTCTCTGGGAAGGTGTGGTTCCCATCCCACTTCAGCTCTTACTTGAAGGACCTGCTGCAGAACCTTCTGCAGGTGGATCTCACCAAGTGCTTTGGGAACCTCAAGAACGGGGTCAATGACATCAAGAACCACAAGTGGTTTGCCATGACTGACTGGATTGCCATCTGTCAGAGAAAGGTGGAAGCTCCCTTCAtaccaaagttttttttttcTCAATGAAAAATGAATTTTAGGGGTGTGCTTGTGCCCCATgagttttctttcacttttttctttttctttctattttttttccggtTGAGGGGGGTTGGATTGAACAGCCAGAGGGCTCTAGAGTTCCATGCATCTAACTTAACATCCACTCCACACCCCCAGGGTTAAGGAGAGCAGGAAAGCCAGATACTGCGGAAGAGGCAACATCAGctgctccccctctcccttctcctccacccTTCCCTGCCTGTTTTCAAtgaatttcttagctccagccatACCCAATCTTGCTGGTGTATCCAGGGGCAGGGTACGGAAAGAGGGGCTCAAATTCAGCCTCCTTCCCTACCCCATCACTGGATACTAAGGATGAACAACAAAGCTAACCTTTCCTTCCATGCAACCCTACCTAGAAAGGGAGATTTTATGACCTGTACAGAGGGCTGCTTGCCAGTGGgctttcttttcatttacatTCAATTCCACAAGTGCCTCCCACCCTCTAAAATTGTCCCACCCTTCCCAAATGCCTTCTGCACTCCTTAAATCCATTCTGATGAGACCTGGGTAGCCAACTAACTCTGTCAAGCCTGAGAACTGGGCTTGGAATCTCGTCCTGAGCTGCTagcctcccagcctccctttcCAGTGGTCTCATGCCAATTATTTTGTGCACCAGCCCCCTGAAGAAGCCTCTCTCCATCCTGGGTGCCTCACTTCTAGCACCTCTTGCCATGCATCCTCACTCACTGCAACCCCAACTCTGATTGTGCTTTTTCTCTCAATAGAAAGGTGGGAGCTGCTGGTGAAATTACCCCATTTATCCTTGTATTTATTCCTTTTATAACTTGTCCCCAAAAGGAGGAGCTTTCAGGCCTGGGTGGGGAACTCGGGTGAGCAAAGGGGGTTGTTCAACCTGTGTGCTTCAAAGGAGGAgacttcctctta
>NM_001277898.1
GGGTTCTATCTGCCCCTACCCTGCACCCATTAGTCTGCAGGTTGAGTTTCTCTTCCTGTTCCCACCCTATCACTCCCTGGCTCCCTCTACAGGCAGGGCTCCCCCCCAGGACTGGCAGCCAAACTGCTGCAGCAGATCTTATGAGGCTTCCGAGCCACCGTAATGCTAGTGCCCTGAGAAAGACTGAGTGATGGCTTCCAGCTCCAACGATGTGAAAGAGTTCCTAGCCAAAGCCAAGGAAGATTTCCTGAAAAAATGGGAGACCCCTTCTCAGAATACAGCCCAGTTGGATCAGTTTGATAGAATCAAGACCCTTGGCACCGGCTCCTTTGGGCGAGTGATGCTGGTGAAGCACAAGGAGAGTGGGAACCACTACGCCATGAAGATCTTAGACAAGCAGAAGgTGGTGAAGCTAAAGCAGATCGAGCACACTCTGAATGAGAAGCGCATCCTGCAGGCCGTCAACTTCCCGTTCCTGGTCAAACTTGAATTCTCCTTCAAGGACAACTCAAACCTGTACATGGTCATGGAGTATGTAGCTGGTGGCGAGATGTTCTCCCACCTACGGCGGATTGGAAGGTTCAGCGAGCCCCATGCCCGTTTCTACGCGGCGCAGATCGTCCTGACCTTTGAGTATCTGCACTCCCTGGACCTCATCTACCGGGACCTGAAGCCCGAGAATCTTCTCATCGACCAGCAGGGCTATATTCAGGTGACAGACTTCGGTTTTGCCAAGCGTGTGAAAGGCCGTACTTGGACCTTGTGTGGGACCCCTGAGTACTTGGCCCCCGAGATTATCCTGAGCAAAGGCTACAACAAGGCTGTGGACTGGTGGGCTCTCGGAGTCCTCATCTACGAGATGGCTGCTGGTTACCCACCCTTCTTCGCTGACCAGCCTATCCAGATCTATGAGAAAATCGTCTCTGGGAAGGTGCGGTTCCCATCCCACTTCAGCTCTGACTTGAAGGACCTGCTGCGGAACCTTCTGCAGGTGGATCTCACCAAGCGCTTTGGGAACCTCAAGAACGGGGTCAATGACATCAAGAACCACAAGTGGTTTGCCACGACTGACTGGATTGCCATCTATCAGAGAAAGGTGGAAGCTCCCTTCATACCAAAGTTTAAAGGCCCTGGGGACACGAGTAACTTTGACGACTATGAGGAGGAAGAGATCCGGGTCTCCATCAATGAGAAGTGTGGCAAGGAGTTTACTGAGTTTTAGGGGTGTGCTTGTGCCCCTTgggttctctttcattttttctttttctttctattttttttccggttgggggtgggagggttggATCGAACAGCCAGAGGGCCCTAGAGTTCCATGCATCTAATTTAACATCCACTCCACACCCCCAGGGTTAAGGAGAGCAGGAAAGCGCTCCAGATACTGGGGAAGGGGCAACATCAGctgctccccctctcccttcttctccaccCTTCCCTGCCTGTTTTCAAtgaatttcttagctccagccatACCCAATCTTGCTGGTGTATCCAGGGGCAGGGTACGGAAAGAGGGCCCCAAATTCAGCCTCCTTCCCGACCCTAGCACTGGATACTAAGGATGAACGAACAGTAACGCCAACCTTCCCTTCCATGCAGCCCTACCTGGAAAGGGAGATTTTATGACCTGTACAGAGGGCTGCTTgccagtggggttttttttttttttcatttaaattaagtTCCACCAGTGCCTCCCACCCTCCAAACTGTCCCACCCTCCCCAAACACCCTCCTCACTCCCTAAATCCATTCTGATGAGACCCGGGTAGCCAACTGACCCTGTCAAGGAAGGAACTGGGCTTGGAATCTCGCCCTGAGCTGCTAGCCTCCCGGCCCCCCTTTCCAGTGGTCTCATGCCAATTGTCCTGTGCATCAGCCCCCTTAAGAAGCCTCCCCCATCCTGGGCGCCTCGCTTCTAGCTTAGCTGTCAGCTGTCCATCACCTCTTGCCGTGCGTCCCCACTCACTGCAACCCCAAGTCTGATTGTGCTTTTTCTCTCAATAGAAAGGTGGGGAGCTGCTGGGGAAATTACCCCATTTATCCCTGTGTTTATCCCTCTCGTAACTTCTCCCAAAAAGGAGGAGCTCTCAGGCCTGGGTGGGGGCCCCGGGTGGACGAGGGGGTCGTTCAACCTGTGTGCTTCGAAGGATGAGACTTCCTCTTGAACAGTGTGCTGTTGTAAACATATTTGAAAACTATTACcaataaagttttgttttaaaataaaa

Publications

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