Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name Myh2P1
Plot displaying the genomic locations of a retrocopy (in chr14) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Mus musculus
Coordinates chr14:55181792-55182010  UCSC
Strand -
Parental Sequence NM_001039545.2
Parental seq. overlap 153 bp
Parental seq. overlap (%) 2.5%
Genomic Region Intragenic (Myh6)
Intragenic (Ccdc3)
Retrocopy Summary Myh2P1, located on chr14:55181792-55182010, is a retrocopy of the parental gene Myh2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Myh2
Full Name myosin, heavy polypeptide 2, skeletal muscle, adult
Also known as MHC2A|MyHC-IIa|Myh2a|Myhs-f|Myhs-f1|Myhsf1
Coordinate chr11:67061853-67088343
Strand +
Gene summary Acts upstream of or within actin-mediated cell contraction; plasma membrane repair; and response to activity. Located in several cellular components, including A band; Golgi apparatus; and actomyosin contractile ring. Is expressed in several structures, including alimentary system; forelimb bud mesenchyme; and skeletal musculature. Human ortholog(s) of this gene implicated in inclusion body myositis and proximal myopathy and ophthalmoplegia. Orthologous to human MYH2 (myosin heavy chain 2). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Human Homo sapiens MYH2P1
Chimpanzee Pan troglodytes MYH2P1
Bonobo Pan paniscus MYH2P1
Orangutan Pongo abelii MYH2P1
Green monkey Chlorocebus sabaeus MYH2P1
Crab-eating macaque Macaca fascicularis LOC102144483P1
Rhesus Macaca mulatta MYH2P1
Marmoset Callithrix jacchus LOC100394720P1
Mouse lemur Microcebus murinus LOC105878349P2
Rat Rattus norvegicus Myh2P1
Rabbit Oryctolagus cuniculus MYH4P1
Horse Equus caballus MYH2P1
Dog Canis familiaris MYH4P1
Panda Ailuropoda melanoleuca LOC100482687P1
Cat Felis catus LOC101085328P1
Pale spear-nosed bat Phyllostomus discolor MYH2P1
Velvety free-tailed bat Molossus molossus MYH2P1
Kuhl's pipistrelle Pipistrellus kuhlii MYH4P1
Greater horseshoe bat Rhinolophus ferrumequinum MYH2P1
Sloth Choloepus didactylus LOC119513051P1
Gorilla Gorilla gorilla Without Homology
Gibbon Nomascus leucogenys Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Chinese hamster Cricetulus griseus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>Myh2P1
GCCGCAATGATGGCTGAGGAGCTGAAGAAGGAGCAGGACACCAGCGCCCACCTGGAGCGCATGAAGAAGAACATGGAGCAGACCATCAAGGACTTGCAGCACCGTCTGGACGAGGCAGAGCAGATCGCCCTCAAGGGCGGCAAGAAGCAGCTGCAAGCAGAAGCGCAATGCA
>NM_001039545.2
TAGCTAGCCATATAAAAGAGTCCCGAACGAGGCTGACTCGTCCTGCTTTAAAAAGCTCCAAGGACCCTCTTATTTCCCAGCTGCACCTTCTCGTTTGCCAGTAAGGGTCTGTGAGTTCAGCAGTCATGAGCTCCGACGCCGAGATGGCCGTTTTCGGGGAGGCTGCCCCTTACCTCCGGAAGTCCGAAAAGGAGCGAATCGAGGCCCAGAATAGGCCTTTTGATGCCAAAACATCTGTCTTTGTGGCGGAGCCCAAGGAATCCTTTGTCAAAGGAACCATTCAGAGCAAAGATGCAGGGAAAGTGACTGTGAAAACAGAAGCAGGAGCGACCCTGACCGTGAAAGAAGACCAGATCTTCCCCATGAACCCTCCCAAGTACGACAAGATCGAGGACATGGCCATGATGACCCACCTGCACGAGCCCGCTGTGCTGTACAACCTCAAAGAGCGTTATGCAGCCTGGATGATCTACACCTACTCAGGCCTCTTCTGTGTCACCGTCAACCCTTACAAATGGCTGCCGGTGTACAACCCCGAGGTGGTGGCGGCCTATCGAGGCAAAAAGCGCCAGGAGGCCCCGCCCCACATCTTCTCCATCTCTGATAACGCCTACCAGTTCATGCTAACAGACAGGGAGAATCAGTCAATCCTGATCACCGGAGAATCCGGGGCCGGGAAGACTGTGAACACGAAGCGTGTCATCCAGTACTTTGCAACAATTGCAGTCACTGGggacaagaagaaggaggaggcaacTTCTGGCAAAATGCAGGGGACGCTGGAGGACCAAATCATCAGTGCCAACCCCCTGCTGGAGGCCTTTGGGAACGCCAAGACCGTGAGGAATGACAACTCGTCTCGCTTTGGTAAATTCATCAGGATCCACTTTGGCACTACGGGGAAACTGGCATCTGCTGACATCGAGACCTATCTGCTAGAGAAGTCCCGGGTCACTTTCCAGCTTAAGGCGGAAAGAAGCTACCATATATTTTATCAGATCACATCCAACAAGAAGCCAGAGCTGATCGAAATGCTGCTGATCACCACGAACCCATATGATTACCCATTTGTCAGCCAGGGGGAGATCAGTGTGGCCAGCATTGATGACCAGGAAGAGCTGATGGCCACTGATAGTGCTATCGACATTTTGGGCTTTACAAATGATGAAAAAGTCTCCATCTATAAGCTCACCGGTGCTGTGATGCATTATGGGAACATGAAGTTCAAGCAGAAGCAGCGGGAGGAGCAGGCAGAGCCAGATGGCACCGAAGTTGCTGACAAAGCTGCCTATCTTCAGGGTCTGAACTCTGCTGACCTGCTCAAAGCCCTCTGCTACCCCAGGGTCAAGGTCGGCAATGAGTACGTCACCAAAGGCCAGACTGTCGAGCAGGTGACCAATGCTGTGGGTGCCCTGGCCAAGGCCATGTATGAGAAGATGTTCCTGTGGATGGTCACCCGCATCAACCAGCAGCTGGACACCAAGCAGCCCCGGCAGTACTTCATCGGGGTCTTGGACATCGCTGGCTTTGAGATCTTTGATttcAACAGCCTGGAACAGCTGTGCATCAACTTCACCAATGAGAAACTGCAACAGTTTTTCAACCACCACATGTTCGTGCTGGAGCAGGAGGAATACAAGAAGGAGGGCATCGAGTGGACCTTCATCGACTTCGGGATGGACCTGGCGGCCTGCATCGAGCTCATCGAGAAGCCGATGGGCATCTTCTCCATCCTGGAAGAGGAGTGCATGTTCCCTAAGGCGACAGACACCTCCTTCAAGAACAAGCTGTATGAGCAGCATCTTGGAAAGTCTGCCAACTTCCAGAAGCCTAAGGTGGTCAAAGGCAAGGCCGAAGCCCACTTCTCCCTCATCCACTATGCGGGCACCGTGGATTACAACATCACTGGCTGGCTGGACAAGAACAAGGACCCACTGAACGAGACCGTGGTGGGGCTGTACCAGAAGTCTTCAGTGAAAACTCTGGCTTATCTCTTCTCTGGGGCACAAACTGCTGAAGCAGagGCAAGTAGTGGTGGAGCTGCCAAGAAAGGTGCCAAGAAGAAGGGGTCCTCTTTTCAGACCGTGTCTGCCCTGTTCAGAGAGAATTTGAACAAGCTGATGACCAATCTCAGGAGCACCCATCCTCATTTCGTGAGGTGTATCATCCCCAATGAAACCAAGACTCCCGGTGCCATGGAGCACGAACTGGTCCTGCACCAGCTGAGGTGTAACGGGGTGCTGGAGGGCATCCGCATCTGCAGAAAGGGCTTCCCCAGCAGGATCCTCTATGCAGACTTCAAGCAGAGatacaaagtgTTAAACGCAAGTGCCATTCCTGAGGGTCAGTACATCGATAGCAAGAAGGCTTCTGAGAAGCTCCTGGGCTCCATTGACATTGACCACACTCAGTATAAGTTTGGTCACACCAAGGTCTTTTTCAAAGCTGGTCTTCTGGGGCTCCTAGAGGAGATGAGAGATGACAAGTTGGCCCAGCTTATTACCCGGACCCAGGCTATGTGCAGAGGGTTCTTGGCGAGAGTGGAGTACCAGAAGATGGTGGAGAGAAGGGAGTCCATCTTCTGCATCCAGTACAACATCCGCGCCTTCATGAACGTCAAGCACTGGCCCTGGATGAAACTCTTCTTCAAGATCAAACCCCTGCTGAAGAGCGCAGAGACCGAGAAGGAGATGGCCACCATGAAGGAGGAGTTCCAGAAAACCAAAGATGACCTTGCCAAGtcagaggcaaagaggaaggAACTTGAAGAAAAGATGGTGTCcctcttgaaagaaaaaaatgacttgcAACTTCAAGTTCAGGCTGAAGCTGAAGGCTTGGCCGATGCAGAGGAGCGATGCGACCAGCTGATCAAAACCAAAATCCAGCTGGAGGCCAAAATCAAAGAGGTGACCGAGAGGGCCGAGGATGAGGAGGAGATCAACGCAGAGCTCACGGCCAAGAAGAGGAAGCTGGAGGACGAGTGCTCAGAGCTGAAGAAGGACATCGATGACCTTGAGCTGACACTGGCCAAGGTTGAGAAGGAGAAGCACGCCACGGAGAACAAGGTGAAAAACCTGACAGAGGAGATGGCAGGCCTGGACGAAACCATCGCCAAGCTGACCAAGGAGAAGAAGGCCCTCCAGGAGGCCCACCAGCAGACCCTGGATGACCTGCAGGCAGAGGAGGACAAAGTCAACACCCTGACCAAAGCCAAAATCAAGCTGGAACAGCAAGTGGATGACCTTGAAGGGTCCTTGGAGCAAGAAAAGAAACTTCGCATGGACCTAGAAAGAGCCAAGAGAAAACTTGAGGGCGACTTGAAGTTAGCCCAGGAGTCCATCATggacattgaaaatgagaaacagcAGCTCGATGAAAGGCTCAAAAAgaAAGAGTTTGAAATGAGCAATCTGCAGAGCAAGATTGAGGACGAGCAGGCCATCGGCATTCAGCTGCAGAAGAAGATCAAGGAGTTGCAGGCCCGCAtcgaggagctggaggaggaaaTCGAGGCAGAGCGGGCCTCCAGGGCCAAAGCAGAGAAGCAGCGCTCTGACCTCTCCCGGGAACTGGAGGAGATCAGCGAGAGGCTGGAAGAAGCCGGCGGAGCCACTTCAGCCCAGATCGAGATGAACAAGAAGAGAGAGGCTGAGTTCCAGAAAATGCGCAGGGACCTGGAGGAGGCCACGCTGCAGCATGAAGCCACAGCAGCCACCCTGAGGAAGAAGCATGCGGACAGCGTGGCCGAGCTCGGGGAGCAGATCGACAACCTGCAGCGGGTGAAGCAGAagctggagaaggagaagagcgagatgaagatggagatcGATGATCTTGCCAGTAATGTAGAGACAGTGTCTAAGGCCAAGggaAACCTCGAGAAGATGTGCCGCACCCTGGAGGACCAGGTGAGTGAGCTGAAGTCAAAGGAGGAGGAACAGCAGCGACTGATCAACGACCTGACAACCCAGAGAGGACGACTGCAGACCGAATCCGGTGAATTTTCCAGGCAGCTTGATGAGAAGGAAGCGCTGGTATCTCAGTTATCAAGGGGGAAGCAAGCATTCACTCAACAGATTGAGGAGCTAAAGAGGCAGCTTGAAGAGGAAGTAAAGGCCAAGAACGCGCTGGCCCACGCCCTGCAGTCCTCCCGCCATGACTGTGACCTGCTGCGGGAACAGTACGAGGAGGAGCAGGAGTCTAAGGCTGAACTGCAGAGGGCGCTGTCCAAGGCCAACAGCGAGGTGGCCCAGTGGAGGACCAAATATGAGACGGATGCCATCCAGCGCacggaggagctggaggaagccaAGAAGAAGCTGGCTCAGCGTCTGCAGGCGGCTGAGGAGCACGTAGAAGCCGTGAACGCCAAGTGCGCTTCTCTGGAGAAGACGAAGCAGCGGCTGCAGAACGAGGTGGAGGACCTCATGCTGGATGTGGAGAGGACCAACGCTGCTTGTGCCGCCCTGGACAAGAAGCAGAGAAACTTCGACAAGATCCTGGCAGAGTGGAAGCAGAAGTATGAGGAAACCCACGCTGAGCTCGAGGCATCCCAGAAGGAGGCCCGCTCCCTGGGCACTGAGCTCTTCAAGATGAAGAATGCCTACGAGGAGTCTCTGGATCAGCTAGAAACCCTGAAGCGAGAGAATAAGAACTTACAGCAGGAGATTTCTGACCTCACGGAACAGATTGCAGAAGGAGGAAAGCGCATCCACGAACTGGAGAAAATTAAGAAACAAGTCGAACAAGAGAAGTGTGAACTTCAGGCTGCTCTAGAAGAAGCAGAGGCATCTCTGGAGCACGAGGAGGGAAAGATCCTGCGCATCCAGCTGGAGCTGAACCAAGTCAAGTCTGAGATCGACAGGAAGATTGCTGAGAAGGATGAGGAGATCGACCAGCTGAAGAGAAACCACATTAGAGTCGTGGAGTCCATGCAGAGCACGCTGGATGCCGAGATCAGGAGCAGGAACGACGCCATCAGAatcaagaagaagatggagggagaccTGAACGAGATGGAAATCCAGCTGAACCACTCCAACCGCATGGCTGCCGAGGCCCTGAGAAACTACAGGAACACACAAGGCATCCTCAAGGACACCCAGTTGCACCTGGACGATGCTCTCCGGGGCCAGGAGGACCTGAAGGAGCAGCTGGCCATGGTTGAGCGCAGAGCCAACCTGCTGCAGGCTGAGATCGAGGAGCTGCGGGCCACGCTGGAGCAGACGGAGAGGAGCAGGAAGATTGCAGAGCAGGAGCTGCTGGACGCCAGTGAGCGCGTGCAGCTCCTCCACACCCAGAACACCAGCCTCATCAACACCAAGAAGAAGCTGGAGACAGACATTTCCCAAATCCAGGGAGAGATGGAGGACATCGTCCAGGAAGCCCGCAATGCAGAAGAGAAAGCTAAGAAAGCCATCACTGATGCCGCCATGATGGCGGAGGAGCTGAAGAAGGAGCAGGACACTAGCGCCCACCTGGAGCGGATGAAGAAGAACATGGAGCAGACCGTGAAGGACCTGCAGCTGCGTCTGGATGAGGCTGAGCAGCTGGCGCTGAAGGGCGGCAAGAAGCAGATCCAGAAACTGGAGGCCAGGGTGCGTGAACTGGAGGGTGAGGTAGAGAGTGAGCAGAAGCGGAATGCTGAGGCCGTCAAAGGTCTGCGCAAACACGAGAGACGAGTGAAGGAGCTTACTTACCAGACAGAAGAAGACCGAAAAAATATTCTCAGGCTTCAGGATTTGGTGGATAAACTCCAGGCAAAAGTGAAATCTTACAAGAGACAAGCTGAGGAGGCTGAGGAACAATCCAACACAAATCTATCCAAGTTCCGCAAGATCCAGCACGAGCTGGAGGAAGCCGAGGAGCGGGCTGACATCGCGGAGTCCCAGGTCAACAAGCTGCGGGTGAAGAGCCGGGAGGTTCACACCAAAATCATAAGCGAAGAGTAAGGCTGTCCCGATGCTGTGGAATGACCGAAGCGAGGCACAAAATGTGAAACCTTTGGTCATGCGCCTGTGTGATTCTATTCCATCCTGTTGTAAGGAAATAAAAAGCCCAAGTTCCTTTGCAAGCAATCA

Publications

PMID - Link Title