Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name Yy1P1
Plot displaying the genomic locations of a retrocopy (in chr8) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Mus musculus
Coordinates chr8:43748723-43748905  UCSC
Strand -
Parental Sequence NM_009537.4
Parental seq. overlap 149 bp
Parental seq. overlap (%) 2.5%
Genomic Region Intergenic
Retrocopy Summary Yy1P1, located on chr8:43748723-43748905, is a retrocopy of the parental gene Yy1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name Yy1
Full Name YY1 transcription factor
Also known as NF-E1|YY-1
Coordinate chr12:108758841-108786074
Strand +
Gene summary Enables DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including immune system development; negative regulation of pri-miRNA transcription by RNA polymerase II; and response to UV-C. Acts upstream of or within with a positive effect on gene expression. Acts upstream of or within several processes, including anterior/posterior pattern specification; camera-type eye morphogenesis; and regulation of gene expression. Located in chromatin and nucleus. Part of PcG protein complex; chromatin silencing complex; and transcription regulator complex. Is expressed in several structures, including brain; early conceptus; embryo mesenchyme; female reproductive system; and hemolymphoid system gland. Used to study pleuropulmonary blastoma. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human YY1 (YY1 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Horse Equus caballus YY1P1
Cat Felis catus YY1P1
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>Yy1P1
CACGTGTGTGCAGAGTGTGGCAAAGCCTTCACGGAGAGCTCGAAACTAAAGCGACATTTTCTGGTGCACACCGGAGAGAAGCCGTATCAGTGCACGTTCGAAGGCTGTGGGAAGCGCTTCTCCCTGGATTTCAACTTGCGCACCCATATCCGCATCCACACCGGGGAGAGGCGCTTTGTGTGT
>NM_009537.4
ctccctctgccttccttccccACGGCCGGCCGCCTCCTCGCCCGCCCGCCCTCCCTCCCGCAGCCCAGGAGCCGAGGCCGCCTGCCGCGGCGGCCGTGGCGGCGGagccctcagccatggcctcGGGCGACACCCTCTACATCGCCACGGACGGCTCGGAGATGCCGGCCGAGATCGTGGAGCTGCATGAGATCGAGGTGGAGACCATCCCGGTGGAGACCATCGAGACCACGGTGGTgggcgaggaggaggaggaggacgacgacgacgaggacggcggcggcggcgaccACGGCGGCGGCGGGGGCGGCCACGGGCACGCcggccaccaccatcaccaccaccaccaccaccaccaccacccgcccATGATCGCGCTGCAGCCGCTGGTGACGGACGACCCGACCCAAGTGCACCACCACCAGGAGGTGATCCTGGTGCAGACGCGCGAGGAGGTGGTCGGCGGGGACGACTCGGACGGGCTGCGCGCCGAGGACGGCTTCGAGGACCAGATCCTCATCCCGGTGCCCGCGCCGGCCGGCGGCGACGACGACTACATAGAGCAGACGCTGGTCACCGTGGCGGCGGCCGGCAAGAGCGGCGGCGGGGCCTCGTCGGGCGGCGGTCGCGTGAAGAAGGGCGGCGGCAAGAAGAGCGGCAAGAAGAGTTACCTGGGCGGCGGGGCCGGCGcggcgggcggcggcggcgccGACCCGGGGAATAAGAAGTGGGAGCAGAAGCAGGTGCAGATCAAGACCCTGGAGGGCGAGTTCTCGGTCACCATGTGGTCCTCGGatgaaaaaaaagatattgaCCATGAAACAGTGGTTGAAGAGCAGATCATTGGAGAGAACTCACCTCCTGATTATTCTGAATATATGACAGGCAAGAAACTCCCTCCTGGAGGGATACCTGGCATTGACCTCTCAGACCCTAAGCAACTGGCAGAATTTGCCAGaatgaagccaagaaaaattaaagaagatgatGCTCCAAGAACAATAGCTTGCCCTCATAAAGGCTGCACAAAGATGTTCAGGGATAACTCTGCTATGAGAAAGCATCTGCACACCCACGGTCCCAGAGTCCACGTCTGTGCAGAGTGTGGCAAAGCGTTCGTTGAGAGCTCAAAGCTAAAACGACACCAGCTGGTTCATACTGGAGAAAAGCCCTTTCAGTGCACATTCGAAGGCTGCGGGAAGCGCTTTTCACTGGACTTCAATTTGCGCACACATGTGCGAATCCATACCGGAGACAGGCCCTATGTGTGCCCCTTCGACGGTTGTAATAAGAAGTTTGctcagtcaactaacctgaaatCTCACATCTTAACACACGCTAAAGCCAAAAACAACCagtgaaaagaagagagaagaccttCTCGACCCGGGAAGCCTCTTCAGGAGTGTGATTGGGAATAAATATGCCTCTCCTTTGTATATTATTTCtaggaagaattttaaaaatgaatcctACACACTTAAGGGACATGTTTTGATAAagtagtaaaaatttaaaaaatactttaataagATGACATTGCTAAGATGCTATATCTTGCTCTGTAATCTCGTTTCAAAAACAAGGTGTTTTTGTAAAGTGTGGTCCCAACAGGAGGACAATTCATGAACTTCGCATCAAAAGACAATTCTTTATACAACAGTGCTAAAAATGGGACTTCTTTTCACATTCTTATAAATATGAAGCTCACCTGTTGcttacaatttttttaattttgtattttccaaGTGTGCATATTGTACACTTTTTGGGGATATGCTTAGTAATGCTGTGTGATTTTCTGGAGGTTGATAACTTTGCTTGCGgtagattttctttaaaagaatggGCAGTTACATGCATACTTCAAAAGTATTTTTCctgtacaaaaaaaaagttatataggTTTTGTTTGCTATCTTAATTTTGGTTGTATTCTTTGATGTTAACACATTTTGTATAATTGTATCGTATAGCTGTATTGAATCATGTAGAATCAAATATTAGATGTGATTTAATAGTGTTAATCAATTTAAACCCATTTTAgtcacttttttttccccaaaaaatACTGCCAGATGCTGATGTTCAGTGTAATTTCTTTGCCTGTTCAGTTACAGAAAGTGGTGCTCAGTTGTAGAATGTATTGTACCTTTTAACATCTGATGTGTACATCCGTGTAACAGAAAGGGCAACAATAAAATAGCGATCCTAAAGAAAGATTACGGCAGAAAGAGCTCTGTAAGCAcagccttattttcttctgttgtcCAGAATACTTAGAATTCTTGAGCCTCCCAGAAATTGGAAGCAAATAAAGCAACTTGAGTTTCCTTTATTTTGCACTCAGTGACAGTGACTGTGATGAGGTCCGTGCATGGACACTAGCATTTCCTACGTGCCCTGAATCCCGAGAGCAGGCAGGAGGCACCCCGAGCTAGGGAACTACCTCAGAGTACACAGACGACCCATGGCTGGCAGGATTGCCCTTGATATCCCGGTGCGTGTGGGAGTGAGACGTTTGCATGGGCCTGATGCTTTCTGAAGGGAAGGCACTGACTGGCAGTGGGTGCGCCAAGGGAGGATGGGCCTGCCTTCTTTCTCATCATCACTCAGGCTGCCTTCAACGGCGGTGGCTCCATGGGTTGTCCAACAGGAAATCTCAGTGCAGTCCTTATTAGATGCTGTCAGATGTAGCAATTGAGTGCCAGTAGCTGTTTGCTTGTAGACACACTTAAGTGCAGAGCGGCAAGGCGATGAGATTATTAGAAAGTTGTACTCAGTGAGTACTTGACTTGTCATGTGTGACCTCTTCAATGTATAATTTTTGAACTTTTACTTACCTAGGGTCAAATACCAGACTTGTTAACTATTTTATAAACTGCCGTGATACATCAAAATCTCATTTATTCAAAATGCAAACCtaactgtctgtctttctgtgctgAATGCTTGACTCCAAGGTAAAATGACAAACAAGTACCAGGTTCAGTCACAAAGAGGCCGGGAGAGCAGCCGCTCGAACACTTAGCCCAATTTCTTATGGCCTCGCCAGGAGGACTGGTGACCTGGAAACAGTGGCCCCGTGGCTCTGGAATTTTGAAGTGCCTTCTGAACCATACATGGAAGTTGTAACTTGGGACATTTGTTTTATTCGTCCAGAATCTGATCCAGTGAGCAGTTGATGGGACTGAGCTCAGCAGCAGACCCAGCTGTGTGCTGGAGGGCAGGCTTTGCTGTGCCTGGCAGTCAGGAGGGGGTAAGACTAAAGGGGCCCCATCAGAGCCAAGTACCCATGTGTCTCCCCCAGGCCTTCGCTCCCTACCATCAGGTTAAGCTTTCCCAAATGCCCTGCAGTCGGAGGCCAGAGCCATGTTGCCCTCCCTCGCCCAATATTGTGCTACCTTCAAGCCTGGCCCTGGCACCTCAAGACCCTTGCCCACGGCTCCACAGCAGAGCAGAAGTGTGCTGTGGAAAAGCCTGCCAGCCACCCTGAGAGTCAGGCCCACGTATAGAGCGAGGCCTCACCCATCCTCTGTGCCTTGATTCCTTGGGAGATGCTTGGCCATCTCTTCTGTCCCTTTCTGTCTGAGTGGAGCAGCGGTCATCATCTTCACCCTTTCTGTGTTGGCATTGTCTTCTCAGTGTGCAGTTAACTTCTGTTGGGAGTTCAAAGACAGCATGGTGTGCGGGTCCTCACTTAGGACAGCAGTGTAGGGACCTGTCACGTCAGTGGCCAGAAGAAAGCTGCTTCTCATTGGCTTTGGCTTAAACCCATTTTGCTTGTTAGAATTTATAGTTTTGTTATAGATGTAATTTACTAATTTGAAATGATGTTCTAACAGTGAGTCCCTTGTCTAGACACTTAAAATCTGATTTGTAAGTAATACTGATAGACATATTTTCTTACATCTGAGCAGAAATAAATGCATGTTTTTAGCAAATGTAATGTAAAAACTCCAGAGGATAAGTTTACACCCAATAagatattattttctatttttaaatttgatatttGCCCCTCTTTGGTAGTGAGGTTGGGGGCATAGTATCTATACAGAGCTGTCGCTCCAGAGTGACATTTATTTCCCGCAGAGATGCTGAGCTCACGCTGTGCTGGGCCTGTGCGATGTGTGTACTTTGCCAGAGGAGCTGAGGAAAACCAAGACTtttcccccatcccccatttGGTTTCCACACACAGGTTCTTCTGAATGCTGCTTGGTTTGCTAAGTTGGTGGGCATGTAAGACCTCTTGAAGAGATGGTGTGTGCAAAGACGGCCCATGTTTCTAGGCAGTTTTAGCTTGTGTCTTCACATAGATGAGAGCCAACTGTCGGTGAAGTGTGTGGTGCTCCAGGGATATGGTGCTGGCATGGCTTGGCACCCACCCCACCTTTCCACTCGGCAGGACTCACCTGTGGTACAGCCCTCAAATCACTGACTAGAGTGTATGTCTATGGCCCAGGAAGTCTTGCCCCCTAAGTTTACCCACTCCCCACAATAGACAGGGATTTGACTACTACTTCCTTTCCTCTGTGCTCCGAATTGACATGATTTAGCCAGTCTGCGGTGCGGTGGGTTTTTATTCTCTTGACTTCTAGCCTACAGGAAGAACAGGGACTTCAGGATCAGAACAGAGATGAGCAGAGTTGCCAGTAGATAGATGCCATCCGTGACTAACTACTCAGAGGCATTGCCCTAGCAGCCCTACTGGCTGCAGAAGCTAGCTCCTTTTCTAGCACAGACTGTTTGAATCTCTGGCCATAAGAGGCCGCATCTGACTTTGCAGCCCTTTGTTGTTAATGTGACCTCTTCTAGAGCCCAGGCCCAGGACCTGGCAGATACACTCTAGCTGAGGACAGGGAAGGGACTCAGAACTCCAAAGCAGATGTGCTTGCTTGCAACATTTAACTCTGATCAGAACAAAAGCTACTCCATGCTTCAAATCACGTGCCAGCAGCATTGACCAGGTAGGTTAGGTCTCCAAAACAGCGAGCTTTCCCCACAGCTTGTTAACTCCTCTCAGGGTAAGCTCAGGTGCCTCAGATGGCTTAATACAGGCCCTTCAGGTGAGTAAGTTGCACTGAGCAGGAGAGGGTAGCTGTGTGGCTAACAGGCTACCCGGCATCTTTGGGCATAGTTGGTCAGTACCGTGCCAGGAAGGTCATTCCCCAGCTGGGACAGCATGTAGACTTCATAGGAAAGGGTGGGTGGCAGATGTGAGCAGCTTAAGGCATTGGTCATTGAGTGTCGGCAGTAGGTCACAGGCGGGGTGCACCTTCCAAGGTGTGCCtagccagcactctggagaccatCAAGGGGGGGCTAGTGAGCAGCACTGTGCTCCGCATTTCAGAGTGGCAGATTTGATGACTAAAGACACTCAGGCACCCCGAGGAACAGTACTGGGGATGTGCAGCTGTGCTGGTTGGTCCGCCTCCCTGCCCGGAGCCACGTGGTGTCTACATCCATAGCATGAGGGAGCAAAGAAGGTATCGTTACCGGAGTCACCTCTTCTTTATAATGCCAGCAACTGTTAAAACCCTTGATGTCTACAAATGGCAAGaaaagttgtgttttcattttctgggAACTCCCATAGGCCCTGGCTCAAGGACTCTGCATTGTGTGTCATGTACATCTCTTAAGTGTTCTTTGCTGTTCTGGAATTGTCCTTGGTTTTTCCTTAGCTCATAGATCAtagacacagaaatattatagtaTTTAAAGCATCCGCATCAAGCATCAGATGGCTTCGCATCCAGAAAAACATAACTCAGTTTGAAGCACCAAGCATGTGTAACATGGCTCTATACAATACAATAAAAAGCGCTAATGTTAAGCTCTTTAA

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