Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name GAPDHP1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Equus caballus
Coordinates chr1:128743223-128744299  UCSC
Strand +
Parental Sequence NM_001163856.1
Parental seq. overlap 930 bp
Parental seq. overlap (%) 72.1%
Genomic Region Intergenic
Retrocopy Summary GAPDHP1, located on chr1:128743223-128744299, is a retrocopy of the parental gene GAPDH. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name GAPDH
Full Name N/A
Also known as G3PDH
Coordinate chr6:35091754-35096110
Strand +
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Gibbon Nomascus leucogenys GAPDHP15
Green monkey Chlorocebus sabaeus GAPDHP48
Baboon Papio anubis GAPDHP28
Rat Rattus norvegicus GapdhP251
Dog Canis familiaris RPS20P27
Panda Ailuropoda melanoleuca GAPDHP22
Cat Felis catus GAPDHP21
Opossum Monodelphis domestica GAPDHP59
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>GAPDHP1
TGATGGTGAAGGCTGGAGTAAACAGTTTTGGCCATATTGGGTGCCTGGTCACCAGGGCTACTTTTAACTCTGGCAAAGTGGATATTGTTGTCATCAGTGACCTCTTCATTGAACTCAACTACATGGTCTACATGTTCCAGAATGGTTCCACCCATGGCCAGTTCAATGGCACTGTCAAGGCTGAGAATGTCACAGTCAAGGCAGTTTGTCATCAATGGAAGTCTCATCTCCATCTTCCAGGAGTGAGATCCCACAACATCAAATGGGGTGATGTTGGTGCTGAATATGTTCTAGAGTCCACTGGTCTTCACTACCTTGGAGAAGGCTGGGGCTGACTTGAAGGGTAGAGTCAAAAGGTCATCATCATCTCTGTCTTTTCTGCAGATGCACCCACGTTTGTGATGGGCATGAACCATGAGAAGTATGACAACTCCCTCAAGATTGTCAGCAATGCCTCCTGCACTACCAACTGCTTGGCCCCCCTGGCCAAGGTCATCCATGACAACTTTGGCATTGTGGAGGGACTCATGACCAGAGTCCATGCCATCACTGCCACCCAGAAGATGGTGGATGGCCCCTCTGGGAAGCTGTGGCATGACCAGCTGTGGGGCTGCCCAGAACGTCATCCTTGGTTCTACTGCTGCCGCCTAGGCTGTGGGAAAGATAATCCCTGAGCCGAATGAGAAGCTCACTGGCATGGCCTTCCATGTCCTCACCCTCAATGTGTCAGTCATGAATCTGACTTGCTGTCTGGAGAAAACTGCCAAATATGATGACATTAAGAAGGTGGTAGAGCAGGCATCAAAGGATGCCTTAACAGGCATCTTGGGCTACACTGAGGACTAGTTTGTCTCTGTGATTTAACAGTGATACCCACTCTTCCACCTTCAACACTGAGGCTTGCACTGCCCTCAAAGACAACTTTGTCAAGTTCATTTCCTGGTATGACAGTGAATTTCACTACAGCAACAGGGTGGTGGACATCATAGTCCACATGGCCTCTAAGGAGTAAGAGTCCCCTGGATCACCAGCCCCAGCAAGAGCATGAGAGAAAGAGAGAGGCCCTCAGCTGCTGGG
>NM_001163856.1
GTTCGACAGACAGCCGCTTCCCTTCCGCACTGCTAGCCGCCTGCCCGCGACGCGATGGTGAAGGTCGGAGTAAACGGATTTGGCCGTATTGGGCGCCTGGTCACCAGGGCTGCTTTTAACTCTGGCAAAGTGGATATTGTCGCCATCAATGACCCCTTCATTGACCTCAACTACATGGTCTACATGTTTCAGTATGATTCCACCCATGGCAAGTTCCATGGCACAGTCAAGGCCGAGCACGGGAAGCTTGTCATCAACGGAAAGGCCATCACCATCTTCCAGGAGCGAGATCCCGCCAACATCAAATGGGGCGATGCTGGTGCTGAATATGTTGTGGAGTCCACTGGTGTCTTCACTACCTTGGAGAAGGCTGGGGCTCACTTGAAGGGTGGAGCCAAAAGGGTCATCATCTCTGCTCCTTCTGCTGATGCCCCAATGTTTGTGATGGGCGTGAACCACGAGAAATATGACAATTCCCTGAAGATTGTCAGCAATGCCTCCTGCACCACCAATTGCTTGGCCCCCCTGGCCAAGGTCATCCATGACCACTTTGGCATCGTGGAGGGACTCATGACCACAGTGCATGCCATCACTGCCACCCAGAAGACCGTGGATGGCCCCTCTGGGAAGATGTGGCGCGATGGCCGAGGGGCTGCCCAGAACATCATCCCTGCTTCTACTGGTGCTGCCAAGGCTGTGGGCAAGGTCATCCCTGAGCTGAATGGGAAGCTCACTGGCATGGCCTTCCGTGTCCCCACCCCTAACGTGTCAGTCGTGGATCTGACCTGCCGCCTGGAGAAAGCTGCCAAATACGATGAGATCAAGAAGGTGGTGAAGCAGGCATCGGAGGGCCCCCTCAAGGGCATCCTGGGCTACACTGAGGACCAGGTTGTCTCCTGCGATTTTAACAGTGACACCCACTCTTCCACCTTCGATGCTGGGGCTGGCATTGCCCTCAACGACCACTTTGTCAAGCTCATTTCCTGGTATGACAATGAATTTGGCTACAGCAATAGGGTGGTGGACCTTATGGCCCACATGGCCTCCAAGGAGTAAGAGCCCCCTGGACCACCAATCACCCAGCAAGAGAAGGAGAAAGGCCCTCAGCTGCTGGGAATGCTTGTCCCAACTTGACCCCCTAACATATTGAGAGTCTCCTGACCTCCACAGTTTCCATCTCAGACCCCCCTGAAGAAGGGGAGGGGCTTGGGGAGCCCTACCTTGTCATGTACCATCAATAAAGTACACTGTACCCAGCCA

Publications

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