Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PIGYP2
Plot displaying the genomic locations of a retrocopy (in chr28) and its respective parental gene (in chr32). Each line represents a retrocopy.
Species Canis familiaris
Coordinates chr28:34415479-34415653  UCSC
Strand +
Parental Sequence NM_001270970.1
Parental seq. overlap 153 bp
Parental seq. overlap (%) 11.8%
Genomic Region Intragenic (LHPP)
Retrocopy Summary PIGYP2, located on chr28:34415479-34415653, is a retrocopy of the parental gene PIGY. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PIGY
Full Name N/A
Also known as -
Coordinate chr32:11862485-11865733
Strand -
Gene summary The protein encoded by this gene is part of the GPI-N-acetylglucosaminyltransferase (GIP-GnT) complex which initiates the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is synthesized in the endoplasmic reticulum and serves as an anchor for many surface proteins. Proteins containing GPI anchors can have an important role in cell-cell interactions. The transcript for this gene is bicistronic. The downstream open reading frame encodes this GPI-GnT complex protein, while the upstream open reading frame encodes a protein with unknown function, as represented by GeneID:100996946. [provided by RefSeq, Aug 2012]

Homology

Species Scientific Name Retrocopy
Panda Ailuropoda melanoleuca PYURFP3
Human Homo sapiens Without Homology
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PIGYP2
GGAGTTCTTGGTGTGCCCACTCTCCGAGAAGCCTCTCAGATACGAAGCATCAACAAATGAATTGATTAATGAAGAGTCGGGAATAGCCCATCTAATTATTGATGGCATCCCTAATGTGGTACCTCCGGCGGCTAGGATGACACATCAAAAACAGAAGCAAGAAGCAATggagcag
>NM_001270970.1
gggccggctgCGCGGGGAGCGGCTGAAGCGGCGGAAGCGGCTGAAGCGGCCGGGCGCTGGCAGGGCGGCGGGTGCGGGCTGCCAGACCATGCTGAGCGGAGCGTGCGGCCGGCTCGCCTCAGCACTGCGGGGGCCGCGCGGGCCGTCGTTCGCGGTCGCCCGCAGGCGCCTTCACGCGTCGGGGTCGCGGCGGCCCTCAGACAAGAGCGAGAGGACGGGAGGCCCGCCCCGCGCCTTCGACCCGGCGCTGCTCGAGTTCCTGGTGTGCCCGCTCTCCAAGAAGCCGCTCAGaTATGAAGCATCGACAAATGAATTGATTAATGAAGAGTTGGGAATAGCCTATCCAATTATTGATGGGATTCCTAATATGATACCACAGGCAGCTAGGATGACACATCAGAATAAGAAGCAAGAAGAAACGGAGCAGCACTAGATCACAATTAAAAGCAACGCCTACAACTGCATTTTCTTAatactacttaattttttaaaagtcagagtgGCAGGTAATAAGCGGGGGAGAAGAATGTTTCTGTCTCTTCCTACGTTGACTGTCCTTATTCCATTGGTCTCTTTAGCAGGACTGTTCTACTCAGCTTCTGTGGAGGAAAACTTTCCACAGGGCTGCACTAGCACAACCAGCCTGTGCTTTTACAGTCTCCTCCTGCCAGTTACCATACCAGTTTATGTGTTCTTCCACCTTTGGACCTGGATGGGTATTAAACTCTTCAGGCATAATTAATACAAACAGAGCCAAGATGATACACATATTAATGATATGTCATGTCTGTCTCTGAAAGCTCAGTGACATGGAAATACTGGAAACCCACTTAATTTGCAGGAAAGGTGCTTTGCCTTGCTTCTCTCAGAGGTTTTGGACTATGGGAGGCTTAAGCTGCAGAAatttcttttgtacttttgttctgcccttattttttgaaaattctaaCATATGACTGCTGTATCAGAAGAAACATTTCAGGAAAGTTTCCTATTGGAAATTAACAGTCCTGACCATCAGCTGATGACTTTATTACCCCATTCATCTAaagttaataattaaaaatttttatgtttattttagattCAAAGTATCTGGTACTGATATGTTAAGGATGACTGAAATAACTCCAAAGGAGTTATGCTGGAGTAGTTGTAGAGAAATACATTTGAGCTAGTGTACTAGAAAACTACAATACAGTGGAAATTTCATGTACTTGCAAACATTGACTTTGTAAAATTACCTTCATTTCTTTGGCATCAAAGGcttacattaataataaaatgacagctttccattt

Publications

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