Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PPIAP35
Plot displaying the genomic locations of a retrocopy (in chrE2) and its respective parental gene (in chrA2). Each line represents a retrocopy.
Species Felis catus
Coordinates chrE2:27222841-27223376  UCSC
Strand -
Parental Sequence NM_001009370.1
Parental seq. overlap 461 bp
Parental seq. overlap (%) 63.8%
Genomic Region Intergenic
Retrocopy Summary PPIAP35, located on chrE2:27222841-27223376, is a retrocopy of the parental gene PPIA. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PPIA
Full Name N/A
Also known as MT-ND1|MTND1|NADH1|ND1|cypA
Coordinate chrA2:62846717-62849370
Strand +
Gene summary N/A

Homology

Species Scientific Name Retrocopy
Human Homo sapiens PPIAP72
Chimpanzee Pan troglodytes PPIAP19
Bonobo Pan paniscus PPIAP17
Gorilla Gorilla gorilla PPIAP18
Orangutan Pongo abelii PPIAP69
Gibbon Nomascus leucogenys PPIAP34
Crab-eating macaque Macaca fascicularis PPIAP13
Rhesus Macaca mulatta PPIAP13
Baboon Papio anubis PPIAP1
Golden snub-nosed monkey Rhinopithecus roxellana PPIAP41
Marmoset Callithrix jacchus PPIAP96
Dog Canis familiaris PPIAP11
Velvety free-tailed bat Molossus molossus PPIAP7
Sloth Choloepus didactylus PPIAP82
Green monkey Chlorocebus sabaeus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Panda Ailuropoda melanoleuca Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PPIAP35
GAGCACTTGGTCCGTGTCTCCTTTGAGCTGTTTGCAGACAAAGGTCCAAAGACAGCAGAAAACTTTTGTACTGTAAGCACTGGGGAGAAAGTATTGGTTATAAAGGTTCCTGCTTTCACAGGATTATTCCAGCATTTATGTGCCAGGGTGGTACCTTCACGTGCCATAATGGCATTGCTGGCAAGTCCGTCTATGGGGAGAAATCTGATGATAAGAATTTCATTCTGAAGCATACAAGTCCTGGCATCTTGTCCATGGCAAATGCTGGACCCAACACAAATGGTTTCCAGTTTTTCATCTGCACTGCCAAGACCTAGTGGTTGGATGGCAAACATGTGGTCTTTGGCAAGGTGAAAGAGTGCATGAATATTGTGGAAGCCATGGAGAACTTTGGGCCCAGGAATAGCAAGACAGCAAAAAGATAACTATTGCTAACTGTGCACAAATCTAATAAATTTGACTTGTGTTTTATCTTAACTTCCAGACCACTCCTGTACCTCAAGAGGGCACCCTTTTGTCCCCATCTGCTTGAAATA
>NM_001009370.1
CGGAATTGCCCGCACCTCTTAACCATGGTCAACCCCATCGTGTTTTTTGACATCGCCGTGGACGGCGAGCCCTTGGGCCGCGTCTCCTTCGAGCTGTTTGCAGACAAAGTTCCCAAGACAGCAGAGAATTTTCGTGCTCTCAGCACTGGGGAGAAAGGATTTGGTTACAAAGGTTCCTGCTTTCACAGGATTATCCCGGGATTTATGTGCCAGGGTGGTGACTTCACACGCCATAATGGCACTGGAGGCAAGTCCATCTACGGGGAGAAGTTTGACGACGAGAATTTCATCCTGAAGCACACAGGTCCTGGCATCCTGTCCATGGCGAACGCCGGACCCAACACGAATGGTTCCCAGTTTTTCATCTGCACCGCCAAGACCGAGTGGTTGGATGGCAAGCACGTGGTGTTTGGCATGGTGAAGGAAGGCATGAACATCGTGGAAGCCATGGAGCGCTTTGGGTCCCGGAACGGCAAGACCAGCAAGAAAATCACCATTGCTGACTGTGGACAAATCTAATAAATTTGACTCGTGTTTTATCTTAACTACCAGACCATTCCTTCTGTAGCTCGGGAGAGCGCCCTTCTGCCCCCATCTGCTCGAAATCTAGAGTCCCTGTGTTCCTGCCGCAGTTCCACGGGTCCTGTGTCCTCCTTACTCCCCTCCAAGTTTAGCTGGATTGCAGAGTGAAGTTTATGATCATGAAATAAAAGCTAAACAACA

Publications

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