Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name BTBD7P2
Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr14). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:111322646-111323394  UCSC
Coordinates (T2T) chr10:112214077-112214826  UCSC
Coordinates (hg19) chr10:113082404-113083152  UCSC
Strand +
Parental Sequence NM_018167.5
Parental seq. overlap 615 bp
Parental seq. overlap (%) 23.8%
Genomic Region Intergenic
Retrocopy Summary BTBD7P2, located on chr10:111322646-111323394, is a retrocopy of the parental gene BTBD7. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name BTBD7
Full Name BTB domain containing 7
Also known as FUP1
Coordinate chr14:93237550-93333036
Strand -
Gene summary Predicted to be involved in regulation of branching involved in salivary gland morphogenesis. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes BTBD7P1
Bonobo Pan paniscus BTBD7P1
Gorilla Gorilla gorilla BTBD7P1
Orangutan Pongo abelii BTBD7P1
Gibbon Nomascus leucogenys BTBD7P1
Green monkey Chlorocebus sabaeus BTBD7P1
Baboon Papio anubis BTBD7P2
Golden snub-nosed monkey Rhinopithecus roxellana BTBD7P2
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>BTBD7P2
gTGAGAGGAGCCTCCAGGAAATGGATGAAAAAACACTGGACCTAAGGTTGAAGGTTTGTAAAGACCTCTGGGATTACACTCCGAAGAAACCGCAGATGGAATGCCTCATTGACTGAAGAAAATGGGTGTGAGTGCATCTAACTATCCTCATTCATGTTCCCTGAGAATAGGAGGAAATTCACATGTCCACGAGACTTTTATAGAAACATCATTCTATTCTCAGCAAGGCTATGGTTGTGAATCAAAATTGTATAGCCTCGCCCAAGGCCATGAGAAACCGTGACAGGAGAAAAAAAAAAGGAATTTCTGGACTTGCCACCCTCAAAAAAAAGTTTATTAAATGCTGAAAATCTAATTGATCTGCTGATCAAGAAGAACTGATCAGCCAAGAACTGTTGCAAGAATTGTTTTCTGTTTGGGATGTTACAGATGTCAATGCATTAGTAGAGGAATATGAGAGAACTTCAGCCTTAAAGGAGTTTTCTCTATAAGTCAATTTGACTAGACCAGAAGCTGAGACATTGCAGAATAATATGGCTGATCTTTATGCGAAGCTATATGTACTGATATAGACCTGATATTTCATGAAACTTGTTTTACTGTTCATTGTACCATTTTTGGCAGCAAGATTTCCATTTTTAAAAACACTGCTTTGTTTCTCACCTAAATGTGGGGCAAAAATAATAATGGACATCAATACAGTTTGTATTAATATGCCCATGTTTTCTGCTTTATTAC
>NM_018167.5
CTGCTCCGTCTAGGAGTCAAAATGGCGGCGAGGGGAACCTGGAGCAGTCCCGGAGCCTGAGCCACTGACAGGAGAGGAGAGggcggcggcggcggcggtgggaggaggatggccgggggtgctggcgccggtgcggacggcggtgctggtggcggcggcggcggaggcgacggcagcggtcccagcggcagcagcagcggcggGAGGAGCCTCCGGGAAATGGATGAAAAGAGGCTGCTGGATCCAGGGTTGAAGGTTCATAAAGGCCTCTGGGATTATACTCTGAAGAACCCGCAGACGGAATGCCTGAGTGACTGAAGAAAATGGGTGCTAATGCATCTAATTATCCTCATTCATGTTCCCCGAGGGTAGGGGGAAATTCACAGGCCCAACAGACTTTTATAGGGACCTCATCCTATTCTCAGCAAGGCTATGGTTGCGAATCAAAGTTGTATAGCCTTGACCATGGCCATGAGAAACCACAAGACAAAAAAAAGAGAACCTCTGGTCTTGCCACCCTCAAAAAGAAGTTTATTAAGCGTCGGAAATCTAATAGGTCTGCCGATCATGCCAAGCAGATGCGAGAACTCCTCTCTGGGTGGGATGTTAGAGATGTCAATGCATTAGTGGAGGAATATGAGGGAACATCAGCATTAAAGGAGCTTTCTCTACAAGCCAGTTTGGCTAGACCAGAAGCCCGGACATTGCAGAAAGATATGGCTGATCTTTATGAGTACAAGTATTGTACTGATGTAGACTTAATATTTCAAGAAACTTGTTTTCCTGTTCATCGTGCCATTTTGGCAGCAAGGTGTCCATTTTTTAAAACACTGCTTTCTTCCTCACCAGAGTATGGGGCAGAGATAATAATGGACATCAATACAGCTGGTATTGATATGCCCATGTTTTCTGCTTTGTTACACTACCTTTATACAGGAGAGTTTGGAATGGAGGACTCAAGGTTTCAAAATGTCGATATCCTTGTTCAGCTTAGTGAAGAATTTGGAACACCAAATTCCCTTGATGTAGATATGCGTGGACTCTTTGATTACATGTGTTATTATGATGTCGTCCTTAGTTTTTCTTCAGACTCTGAACTGGTTGAAGCTTTTGGTGGAAATCAGAACTGTTTAGATGAAGAGCTCAAAGCCCACAAGGCTGTTATTTCTGCACGGTCCCCATTTTTTCGAAATTTATTACAAAGGAGGATACGAACTGGTGAAGAAATCACAGACCGAACTTTGAGGACTCCCACAAGAATTATATTAGATGAGTCCATTATACCAAAAAAATATGCAACAGTGATATTACACTGTATGTATACCGACGTGGTGGACCTCTCTGTTTTGCACTGTAGCCCCTCTGTGGGGAGTCTCAGTGAAGTTCAGGCTCTCGTCGCAGGGAAGCCAAACATGACCAGGGCAGAAGAAGCCATGGAACTTTACCACATAGCACTGTTCTTGGAATTTAACATGCTTGCACAAGaggagactacagtcatcaggcctgcctgtgcagcagagctttcaaacagctgcttactgcctcaatcttaaatatgaaaacccatccaaggataactggacatttgaggaaagcttccaaattgagacagagatcagagcaaaaagaacaaagtcctggaggaagcagacaatgaagggagcagaagaaaacttcagtagaatcaaaatatccttatataaaagaactttttatggaatcagtgagacataagcaggatgctattaaagtaaaaacaggagcttttagaaataagatagcagaaatgaaagatataatggaagcattgaaaggtacagttgaggaaatctagaaagtaaataatataataaagagatgagtggagacaaataaaactagagtattcatccagggtctaacatctaacaaatagtggctttagaaatatataccagagaaaagtgaagagaagacagtatctaaggagtaatataagaaatatttccaaaactaaaggaATTTCTATATAAAAAGTTTCTTtttcagaacactggggaaaaagagacaattttaaaatgttgcagggaggagaaaaattaggttccatgcaaagaaataggaatcagatggtattgagattttcagtagcaacaactgaataccacaatacagtgaagtagtgtcttccaaaagctgatggaaaattattttaaacacaaaatcctatatttagccaaacagtcaatcaagtgtaaggctaaataaaggcatttttcagtcatacctcgaaaaactgcctgtgtagggatatttcccctgcttccccactcaggcagctgctgggaatgtattccaccaaatgacgaagcaaaccaagaacaaagaagtgaaggatctagaaaatgggctccaacacgggaaggaagcaaagggagatcccacgcatcagccacacagtaggtcttgtgggcattcagtctagcccagaccgggagggtgaaagtctccaaggaaagaggtgtctcggaagaaatcaattactttcaatgtttgaacattaaatagcaaatgacaaagcaa

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