Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CTAGE7P
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Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr14). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:130106003-130108831  UCSC
Coordinates (T2T) chr10:131034994-131037822  UCSC
Coordinates (hg19) chr10:131904267-131907095  UCSC
Strand +
Parental Sequence NM_005930.4
Parental seq. overlap 2637 bp
Parental seq. overlap (%) 72.6%
Genomic Region Intragenic (C10orf143)
Retrocopy Summary CTAGE7P, located on chr10:130106003-130108831, is a retrocopy of the parental gene MIA2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MIA2
Full Name MIA SH3 domain ER export factor 2
Also known as CTAGE5|MEA6|MGEA|MGEA11|MGEA6|TALI
Coordinate chr14:39233915-39388522
Strand +
Gene summary This gene encodes s receptor in the endoplasmic reticulum, which plays a role in the export of large pre-chylomicrons and pre-very low density lipoproteins (pre-VLDLs). Three major classes of transcripts are generated from this gene- melanoma inhibitory activity 2-specific transcripts, cTAGE family member 5-specific transcripts and transcripts that include exons from both these transcript species (TANGO1-like or TALI). Additionally, alternative splicing in these transcripts results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Sep 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes MIA2P4
Bonobo Pan paniscus MIA2P3
Gorilla Gorilla gorilla MIA2P5
Orangutan Pongo abelii MIA2P2
Gibbon Nomascus leucogenys MIA2P2
Green monkey Chlorocebus sabaeus CTAGE5P4
Baboon Papio anubis MIA2P5
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Related Sequence

>CTAGE7P
TGGCCGGGGTTACTGCGGCGACCGCCAGAGCAGCCTTGGCGCTATGTTGGAGCCAGGGGCTACCCCTCAGCGGTACTTGGGGCTGGTCCTGGGGGAGCCACGCAGGGTTGTGGCAGCGCTGCCTGAAAGTATGAGACTGGATTCGAATCCTCATGGTTTTCCATGGGAAATGGTGATATGTGCAGCTGTTGCTGCATTTTTTGCTGTTCTCCTTTTTCTGTGGAGAAGTTTTAGATCGGTTAGGAGTCGGCTTTATGTGGGAAGAGAGAAAAAGCTTGCTATAATGCTTTCTGGACTAATTGAAGAAAAATGTAAACTACTTGAAAAATTTAGCCTTGTTCAAAAAGAGTATGAAGACTATGAAGTAGCGTCATCGTTAGAGGATGCCAGCTTTGAGAAGGCGGCAGCAGAAGCACGAAGTTTGGAGGCAACCTGTGAAAAGTTGAACAGGTCCAATTCTGAACTTGAGCATGAAATTCTCTGTCTAGAAAAAGAGTTAAAAGAAGAGAAATCTAAACATTCGCAACAAAATGAATTGATGGCGGATATTTCAAAAACGATACAGCCTCTAGCAGATGAGTCAGAATCCCTCAAATCACAAGTAGCTGAAGCCAAAATGATCTTCAAGAGATTTAAAATGACTGAGAAACAACTGAAGATAGCAATAAAAGATGCTTTGAATGAAAACTCTCACCTTCAGGAAAGCCAGAAACAGCTTTTGCAAGAAGCTGAAGTATGGAACGAACAAGTGAATGAACTTAATAAACAGAAAATAACATTTGAAGACTCCAAAGTACATGCAGAACAAGTTCTAAATGATAAAGAAAATCACATCAAGACTCTGACTGAACATTTGCTAAAGATGAAAGATTGGGCTGCTAGGCTTAGAGAAGACGTAACGGATGATGATAACTTAGAAGTGAACAGTGAATCAGAAGATGGTGCTTACTTAGATGATCCTCTAAAAGGAGCTCTGAAGAAACTGATTCATGCTACTAAGTTAAATGCTTCTTTAAAAACCTTAGAAGGAGAAAGAAACCAAATTTATATCCAGTTACCTGAAATTGATAAAACAAAGGAAGAGCTTACAGAGCATATTAAAAATCTTCGGACTGAACAAGCATCTTTGCAGTCAGAAAACACACATTTTGAAAGTGAGAATCAGAAGCTTCAACAGAAACTTAAAGTAATGACTGAATTATATCAAGAAAATGAAATGAAACTCTACAGGAAATTAACAGTAGAGGAAAATAGCCGGTTAGAGAAAGAAGAGAAACTTTCTAAGGTAGACAAAAAGATCAGCCATGCCACTAAAGAGCTGGAGACCTACAGACAGCGAGCCAAAGATCTTGAAGAAGAATTGGAGAGAACTATTCATTATTATCAACGGCAGATTATTTCCCATGAGAAAAAGGCACATCATAACTGGTTGGCAGCTTGGGCTGCTGAAAGAAACCTCAATGATTTAAGGAAAGAAAATGCTCACAACAGACAAAAATTAGCTGAAACAGAGTATAAAATAAAACTTCTAAAAAAAGATCCTTATGTACTTGATGTTCCAAATACAGCATTTGGCAGAGAGCATTCCCCATATGGTCCCTCATCATTGGGTCGGCCTTCATCTGAAACGAGAGCTTTTCTCTCTCCCGCAACTCTGTTGGAGGGTCCACTCAGACTCTCACCTTTGCCTCCAGGGGGGGAAGGAAGAGGCTCAAGAGGCCCAGGGAATCCTCTGGACCATCAGATTACCAAGGAAAGAGGAGAATCAAGCTGTGAAAGGTTAACCGATCCTCACAGGTCTCCTTCTGACACTGGGTCCCTGTCACTTCCGAGGGAACAGGACCGTAGGATGATGTTTCCTCCACCAGCGCAATCATATCTTGATTCAGCTCTTCCTCCACAAAGGCAAGACAGATTTTATTCTAACTCTGGTGGACTGTCTGGACCAGCAGAACTCAGAAGTTTTAATATGCCTCCTTTGGATAAAATGGATGGGTCAATGCCTTCAGAAATGGAATCCAGTAGAAATGACACCAAAGATGATCTTGGTAATTTAAATATCCCTGATTCATCTCTCCCTGCTGAAAATGCAGCAACTGGCCCTCGCTTTGTTCCTCCACCTCTTGCCCTAATCAGAGGTCCACTGTTTCCAGTGGATACAAGGGGCCCGTTCATGAGAAGAGCACCTCCTTTCCCCCCACCTCCTCCAGGAACCAGGTTTGGAGCTTCTCGAGATTATTTTCCACCAGGGGATTTCCCAGGTCCACCACATGCTCCGTTTGCAATGAGAAATGTCTATCCACCGAGGGGTTTTCCTCCTTACCCTCCCCCAAGACCTGGATTTTTCCCCCGACCCCCACATTCTGAAGGTAGAAGTGAGTTCCCTTCAGGGCTGATTCCGCCTTCAAATGAGCCTGCTACGGAACATCCAAAACCGCAGCAAGATACCTGGCAATATTTTTGCTCTCTTCAAAAGTAATTCTGACTGATCTCATTTCAAGTAACTGCTGTTACTTAAGTGATTACACTTTTGCTCAAATTGAAACTTAATGGAATTATAATTCTTAGGATAGTATTTTGTAAATAAGGATGATTTAAATATGAATCTTATAAGTAAATTATTTCCATTGTATTTTATTCGATAGTATAACTATTTTAATTTGATTAATCCACTATTATAGAAACAACAGTGGGAGTTTTACGTATGTAATCTTGCAGGTGGGGAGGCTTTAAATTCTAAAGGCTGTGTCTTTATGCCAACAACTGTATTTACTGTAGGTGTAGACAAATGTGAAAGTAACTTTATGCTTAAATAAATTTTAGTTGATT
>NM_005930.4
GTGTGTTCTCCGCCGTTTATTGTGGCCCCGACAGGCCGGGGTTACTGTGGCGACCACGAGAGCAGCTTTGGCGCTATGGAGGAGCCCGGGGTTACCCCTCAACCGTATTTGGGGCTGCTCCTGGAGGAGCTACGCAGGGTTGTGGCAGCACTGCCTGAAGGTATGAGACCAGATTCTAATCTTTATGGTTTTCCATGGGAATTGGTGATATGTGCAGCTGTTGTTGGATTTTTTGCTGTTCTCTTTTTTTTGTGGAGAAGTTTTAGATCGGTTAGGAGTCGGCTTTATGTGGGACGAGAGAAAAAGCTTGCTCTAATGCTTTCTGGACTAATTGAAGAAAAAAGTAAACTACTTGAAAAATTTAGCCTTGTTCAAAAAGAGTATGAAGGCTATGAAGTAGAGTCATCTTTAAAGGATGCCAGCTTTGAGAAGGAGGCAACAGAAGCACAAAGTTTGGAGGCAACCTGTGAAAAGCTGAACAGGTCCAATTCTGAACTTGAGGATGAAATACTCTGTCTAGAAAAAGAGTTAAAAGAAGAGAAATCCAAACATTCTGAACAAGATGAATTGATGGCGGATATTTCAAAAAGGATACAGTCTCTAGAAGATGAGTCAAAATCCCTCAAATCACAAGTAGCTGAAGCCAAAATGACCTTCAAGATATTTCAAATGAATGAAGAACGACTGAAGATAGCAATAAAAGATGCTTTGAATGAAAATTCTCAACTTCAGGAAAGCCAGAAACAGCTTTTGCAAGAAGCTGAAGTATGGAAAGAACAAGTGAGTGAACTTAATAAACAGAAAGTAACATTTGAAGACTCCAAAGTACATGCAGAACAAGTTCTAAATGATAAAGAAAGTCACATCAAGACTCTGACTGAACGCTTGTTAAAGATGAAAGATTGGGCTGCTATGCTTGGAGAAGACATAACGGATGATGATAACTTGGAATTAGAAATGAACAGTGAATCGGAAAATGGTGCTTACTTAGATAATCCTCCAAAAGGAGCTTTGAAGAAACTGATTCATGCTGCTAAGTTAAATGCTTCTTTAAAAACCTTAGAAGGAGAAAGAAACCAAATTTATATTCAGTTGTCTGAAGTTGATAAAACAAAGGAAGAGCTTACAGAGCATATTAAAAATCTTCAGACTGAACAAGCATCTTTGCAGTCAGAAAACACACATTTTGAAAATGAGAATCAGAAGCTTCAACAGAAACTTAAAGTAATGACTGAATTATATCAAGAAAATGAAATGAAACTCCACAGGAAATTAACAGTAGAGGAAAATTATCGGTTAGAGAAAGAAGAGAAACTTTCTAAAGTAGATGAAAAGATCAGCCATGCCACTGAAGAGCTGGAGACCTATAGAAAGCGAGCCAAAGATCTTGAAGAAGAATTGGAGAGAACTATTCATTCTTATCAAGGGCAGATTATTTCCCATGAGAAAAAAGCACATGATAATTGGTTGGCAGCTCGGAATGCTGAAAGAAACCTCAATGATTTAAGGAAAGAAAATGCTCACAACAGACAAAAATTAACTGAAACAGAGCTTAAATTTGAACTTTTAGAAAAAGATCCTTATGCACTCGATGTTCCAAATACAGCATTTGGCAGAGAGCATTCCCCATATGGTCCCTCACCATTGGGTTGGCCTTCATCTGAAACAAGAGCTTTTCTCTCTCCTCCAACTTTGTTGGAGGGTCCACTCAGACTCTCACCTTTGCTTCCAGGGGGAGGAGGAAGAGGCTCACGAGGCCCAGGGAATCCTCTGGACCATCAGATTACCAATGAAAGAGGAGAATCAAGCTGTGATAGGTTAACCGATCCTCATAGGGCTCCCTCTGACACTGGGTCTCTGTCACCTCCATGGGACCAGGACCGTAGGATGATGTTTCCTCCGCCAGGACAATCATATCCTGATTCAGCCCTTCCTCCACAAAGGCAAGACAGATTTTGTTCTAATTCTGGTAGACTGTCTGGACCAGCAGAACTCAGAAGTTTTAATATGCCTTCTTTGGATAAAATGGATGGGTCAATGCCTTCAGAAATGGAATCCAGTAGAAATGATACCAAAGATGATCTTGGTAATTTAAATGTGCCTGATTCATCTCTCCCTGCTGAAAATGAAGCCACTGGCCCTGGCTTTGTTCCTCCACCTCTTGCTCCAATCAGAGGTCCATTGTTTCCAGTGGATGCAAGAGGCCCATTCTTGAGAAGAGGACCTCCTTTCCCCCCACCTCCTCCAGGAGCCATGTTTGGAGCTTCTCGAGATTATTTTCCACCAGGGGATTTCCCAGGTCCACCACCTGCTCCATTTGCAATGAGAAATGTCTATCCACCGAGGGGTTTTCCTCCTTACCTTCCCCCAAGACCTGGATTTTTCCCCCCACCCCCACATTCTGAAGGTAGAAGTGAGTTCCCCTCAGGTTTGATTCCACCTTCAAATGAGCCTGCTACTGAACATCCAGAACCACAGCAAGAAACCTGACAATATTTTTGCTCTCTTCAAAAGTAATTTTGACTGATCTCATTTTCAGTTTAAGTAACTGCTGTTACTTAAGTGATTACACTTTTGCTCAAATTGAAGCTTAATGGAATTATAATTCTCAGGATAGTATTTTGTAAATAAAGATGATTTAAATATGAATCTTATGAGTAAATTATTTCAATTTTATTTTAGACGGTATAACTATTTCAATTTGATTAATCCACTATTATATAAACAATAGTGGGAGTTTTATATATGTAATCTTTCAGGTGGGGAGGCTTTAAATTCTGAAGTCTGTGTCTTTATGCCAAGAACTGTATTTACTGTGGTTGTGGACAAATGTGAAAGTAACTTTATGCTTAAATAAATTATAGTTGATTTAAAGATTTGTTTGGCATTGATAATAATAAAATCAGTAGTTTTTCTATAACTATGGCTCTATTAACTTTTTTCCTTTTACCAATAACTTTGAGGTGCAAAACTCAAACTTATGTGGGTCTTTTGTGTTCAATTATGTTATGACAAATGTGCTCTCTTTCTTGTAAATAGACATGAGTGGCCCAAAGCAACAAATTAATACACTTTTAAAAGTCAAAATTGATTATATTTTAAAGATAACCAGGATATTATCTAATGGTGAATTGTAGAATTTTGATCTTCTTATTCACTGAGTTTCTTGCACGGTTTCTTTATTGCTTTTTTTTCCCCGCCTGTTCTTTTGTAAGGTATTTACTATTTTCTGTGGAGGATATTGAGATGTACTACAGGATAACTGTAGTGAATGATGTGTCATCATTTTGAGCTTTGGACTCAATATCTTTAGTGTTTCCCTAAATCAGATTTGTAGGTCATGTTAAGCTTCTTGCACATTAATATGATTATGGAAGGAAAGGCAGTGAAGCATAACTAATAAACATCATAATACTTAACGTTGCCCAGTTGGTTGTTTTAGTATTAGACTTTTTTTTCAATGCCAAAAGATAGAAGATTAAATATTCTTGAATAAAGCAGTGATATATATTGGAACACTTCACCCCAGCATTTCCCCAGGTGTTGTTTGGAACACTGATCTTGTGAAGTATTTTTGCTCCCTTTCTATTCTAACCCTCACCTcaaaaaaaaaaaacaaaaaacaaaaaa

Publications

PMID - Link Title
33961781Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.
16201836Emergence of young human genes after a burst of retroposition in primates.
12477932Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.