Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name LUZP4P1
Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chrX). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:21247769-21248096  UCSC
Coordinates (T2T) chr10:21266494-21266821  UCSC
Coordinates (hg19) chr10:21536698-21537025  UCSC
Strand +
Parental Sequence NM_016383.5
Parental seq. overlap 282 bp
Parental seq. overlap (%) 16.1%
Genomic Region Intragenic (NEBL)
Retrocopy Summary LUZP4P1, located on chr10:21247769-21248096, is a retrocopy of the parental gene LUZP4. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name LUZP4
Full Name leucine zipper protein 4
Also known as CT-28|CT-8|CT28|HOM-TES-85
Coordinate chrX:115289715-115307563
Strand +
Gene summary This gene encodes a leucine-zipper protein that was first defined as a cancer testis antigens. The encoded protein is an RNA binding protein that interacts with the mRNA export receptor nuclear RNA export factor 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes LUZP4P1
Bonobo Pan paniscus LUZP4P1
Gorilla Gorilla gorilla LUZP4P1
Orangutan Pongo abelii LUZP4P1
Gibbon Nomascus leucogenys LUZP4P1
Green monkey Chlorocebus sabaeus LUZP4P1
Crab-eating macaque Macaca fascicularis LUZP4P1
Rhesus Macaca mulatta LUZP4P1
Baboon Papio anubis LUZP4P1
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>LUZP4P1
CCTAACACTTTCTGAAAAAGTGCTGACAAATCATCCCAGCTGGACAAAGTTTAATTTCCTAGATATGTCTCTAGATGACATTATAATCTATAAAAAGTTAGAAGAGATAAACGCTGAAAAAGAATAAAAGAACCATAGTAAAAAGGATTCACCTTCAAGACAGCAATCAAATGCTCATGGACATCACCAGCAGAGAGGATACCCAAGATTCAGAAGCAACTCTGAGGAAGGAAATTATGATTAAAAAAAAAAAAAAAACCATCCCAAGAAACTTCTGGATTCAAGTCTGGACGGCACCCTTTAAATGGGCAGCCTTTAACTGAT
>NM_016383.5
ACACGCGCCCTACCTCGGAGTGTGTGGCGCCATGATGCAGGGAAGATGGCTTCGTTTCGGAAGCTAACGCTTTCTGAAAAAGTGCCGCCAAATCATCCCAGTCGGAAAAAGGTTAACTTCCTAGATATGTCTCTAGACGACATTATAATCTATAAAGAGTTAGAAGGGACAAATGCTGAAGAAGAAAAGAATAAAAGACAGAACCATAGTAAAAAGGAATCGCCTTCAAGACAGCAATCAAAAGCTCATAGACATCGCCATCGGAGAGGCTACTCAAGATGCAGAAGCAACTCTGAGGAAGGAAATCATGATAAAAAACCATCCCAAAAACCTTCTGGATTCAAGTCTGGACAACACCCTTTAAATGGGCAGCCTTTAATTGAGCAGGAGAAGTGCAGTGACAATTATGAGGCCCAAGCAGAGAAGAATCAAGGCCAGTCAGAGGGGAACCAGCATCAATCAGAAGGAAATCCGGACAAATCAGAAGAATCCCAGGGCCAACCAGAAGAAAATCATCATTCTGAGCGATCCCGAAACCACTTAGAGAGATCTCTTTCTCAGTCAGACAGATCTCAAGGGCAGCTAAAGAGACATCATCCCCAATATGAGAGATCTCATGGCCAATACAAGAGATCTCATGGTCAATCTGAGAGATCTCATGGCCACTCAGAGAGATCTCATGGTCACTCAGAGAGATCTCATGGTCACTCAGAGAGATCTCATGGTCACTCAAAGAGATCTCGTAGCCAGGGAGATCTTGTGGACACTCAGAGTGATCTCATAGCCACTCAGAGAGATCTCATAGCCACTCAGAAAGATCTCATAGCCACTCAGAGAGATCTCATAGCCACTCAGAGAGATCTCATAGTCACTCAGAGAGATCTCGTGGCCACTGAGAGAGATCTCATAAATCAGTCAGGGAGATCTCATGGCCAATCAGAAAGACATCAGAGATACTCAACAGGTAAAAATACAATAACTACTTAATCATCAGAACAATGTGTTGAATTCTGTGGAAATAGAAAAGCATATATCTATATTCTAATGGCTAAATATGTATTTGTTGAAACATGTATATTGGGACAAAGACATAAATATTAGAATGGAGGTAATACATACATAGTATCAATATTGTTTCAACTTGATGTCCTCTAAGCTATCATCCAGTTACCCAGGATGTCCCATTAAGTTGTTCCCGGTAGGTCTGCTTTCCCTGGAAGAGCCGTATGTACTCAGCCTTTCCTATTGGGCCTTCCCCACAATTAGAATATTTTGACTTAGTGTCCTGTCCCCCTTGGACGTTCCAACTTGACTTAGTGTCCAGTGCCCCTTGGACATTCCAACCTGGTAGGTAAGCTAATCTAACAACTAACTGCCAAATTGATAATATATAATCTATGATAATGAATATCTCTTTTGTGTCTCCTTCCTAAGCCATCCTCAGAGAGTccttagcagacaaatggtagatgtatctttgggcagctgaacttttctgctttcctcaaatcagaccatatgagaggatatattctatgcatagatgtaatgctaaccttCTGAATATATTTTGAATACATTTATATATTCACTGTTGCCTTATAAAACTGTTAGGGTAGGTCTGTCTACCCTAGCAAAAGAAACACAGAAATTTAAATGTACTGGGAGTTATGTTGTTAAAAACACAAGATATGTTAACTGCAGTTTGTTTGGTTATTCAATAAAAGTTTTAGTTTTAATTTCTCA

Publications

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