Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name COQ10BP3
Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:24660544-24660908  UCSC
Coordinates (T2T) chr10:24679222-24679586  UCSC
Coordinates (hg19) chr10:24949473-24949837  UCSC
Strand -
Parental Sequence NM_001320819.2
Parental seq. overlap 328 bp
Parental seq. overlap (%) 16%
Genomic Region Intragenic (ARHGAP21)
Retrocopy Summary COQ10BP3, located on chr10:24660544-24660908, is a retrocopy of the parental gene COQ10B. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name COQ10B
Full Name coenzyme Q10B
Also known as -
Coordinate chr2:197453423-197475310
Strand +
Gene summary Predicted to enable ubiquinone binding activity. Predicted to be involved in cellular respiration and ubiquinone biosynthetic process. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes COQ10BP2
Bonobo Pan paniscus COQ10BP2
Gorilla Gorilla gorilla COQ10BP2
Orangutan Pongo abelii COQ10BP2
Gibbon Nomascus leucogenys COQ10BP2
Green monkey Chlorocebus sabaeus COQ10BP2
Crab-eating macaque Macaca fascicularis COQ10BP2
Rhesus Macaca mulatta COQ10BP2
Baboon Papio anubis COQ10BP2
Marmoset Callithrix jacchus COQ10BP2
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>COQ10BP3
CGATATTTAGCTTCCTGTGGTATACTGATGAGCAGAGCTCTTCCGCTACATATGTCAATTTTGATTAAGGAGATATGTGCAATAACTTTCTTCACAATCGCTGCACCATTAATAAAAGGAAATATTCAGAGAGGAGGATTTTAGGCTATTTAATGCAGGAAATGTATGATGTTGTATTGGGAATGGAGGATTATAAGCATTTCATTCTTTGGTGCAAAAAATCAGATATAATATCAGAGAGATCTGGATATTACAAAACATAATTAGAAATTGAGTTTCCACCAGTGTTGGAGTGATATTCAGCAGTAACCTTGGTGAAACCTCATTTGGTAAAGGTATCCTGTACTGATGGGAGACTTTTCAAG
>NM_001320819.2
AGAAGGGTTGCCGGCTGCTGGCTGTATGGGAGTTTGTGTTTGGCGATATTTAGCTTCCTGTGGTATACTGATGAGCAGAACTCTTCCACTACATACCTCAATTTTGCCTAAGGAGATATGTGCACGAACTTTCTTCAAAATCACTGCACCATTAATAAACAAAAGGAAAGAATATTCAGAGAGAAGAATTTTAGGATATTCAATGCAGGAAATGTATGATGTAGTATCGGGAGTGGAGGATTACAAGCATTTTGTTCCTTGGTGCAAAAAATCAGATGTTATATCAAAGAGATCTGGATATTGTAAAACAAGATTAGAAATTGGATTTCCACCTGTGTTGGAGCGATATACATCAGTAGTAACCTTGGTGAAACCTCATTTAGTAAAGGCATCTTGTACTGATGGGAGACTTTTCAATCATTTGGAGACTATTTGGCGTTTTAGCCCAGGTCTTCCTGGCTACCCAAGAACTTGTACCTTGGATTTTTCAATTTCTTTTGAATTTCGATCACTTCTACATTCCCAGCTTGCCACACTCTTTTTTGATGAAGTTGTGAAGCAGATGGTAGCTGCCTTTGAAAGAAGAGCATGTAAGCTGTATGGTCCAGAAACAAATATACCTCGGGAGTTAATGCTTCATGAAGTCCATCACACATAAAGGCAAAAAAGAACTGGTGCCACCTGCTTCTGACTTTAGTTTGTTCACTTTTAGGAAGTATTTTCATGACATGTTTTCAGAAGCCAGAAAGCATTTGTTAAACGCAGCTTTGGTTATAAACCTGCACCATTGAAAATTTGCACATAGAATATAGACTCACTTGTACATAGAATTATTTCTTCAAGTATAATTCAAAATAATATGGACATTATCATGTTCTGCATTACAATAATGGGATGTCATCACCATTGCTAGAATACTGGCATGATTCTTCTGAGCAGAAGTTGAAACTGTAAATTTAAACCTTTTAATTATCACCTTACCTGAAAGAGGTTAGTTAAGATATTCACACAGTATGTATTATATTAACCATATCACACTTAAGTTATTAAATTCAGACTATTTGTAACTTATTGTTATAGGGCCTGCCGTATGGCTTAGGATATTTGAGTAATCATATATTTAAAGTAAAAACTTTGggctgggcacagtggctcacacctgtaatcccagcacttggggaagctgaggtgggcagatcagttgaggtcaggagttctagaccagcctggtcaacatggcgaaaccccatctctactaaaaatacaaaaattagctgggcgtggtggcacacacctgtaatcccagttacttgggaggctgaggcacaagaatcgcttgaacccgggaggcggaggttgcagttagccaagatcgccctgctgcactccagcctgggcaacagagggagactctgtctccaaaaacaaaaacaaaaaCTGTTAGTGAAGGTTCCCTGGGACTTTTGATATTTTAAAAATTGTTCTTATGACTAGTAGATAAATTCATTGCCATAATGAGGCTAGCTCCCAGATAAACAGTGTAttttcttctttttttttttttttttGGTGAGTGGTCCAGAGCTTTAAGCTACTTTTCCAGTAGTTTGCCACTTTCTCCGAGGTAGTTTGGCTGCTCTTTCAGTAATGCTAATTGTGTGTCAAATTTTGTCTACAACAGTAGGCAACAGATGAAGATAAGTTGGTTGAATGTCTCCAGCACTATGCATCCCTATTTTCTATTTATTGTGTACACTCACTTTCAGTAATGTGTTTCAAACTGGTATTTTTTAAAAAACAAATCAATGTAAGGACTGAAGTTGAAGTAGCAATGTAATAAAGTTAATTTGTTTATTTTTTGTACAGTTAGTTTGGTTATTGAAATCTTCCTATATTGTTTAAATGTGTATTTGCATAGACATAGTAAAGTGTTACAGCATTTCATGTCTTAAAAATATCTATGAAGATATCTAAAATATCTATTTCTATGAAGAAACAGACTTTAACAAATATAAGCAAAATTCAGTTTTCTTTTAACCAGTCA

Publications

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