Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name SSBP1P4
Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:29890940-29891447  UCSC
Coordinates (T2T) chr10:29922067-29922574  UCSC
Coordinates (hg19) chr10:30179869-30180376  UCSC
Strand -
Parental Sequence NM_001256512.1_2
Parental seq. overlap 448 bp
Parental seq. overlap (%) 50.9%
Genomic Region Intergenic
Retrocopy Summary SSBP1P4, located on chr10:29890940-29891447, is a retrocopy of the parental gene SSBP1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SSBP1
Full Name single stranded DNA binding protein 1
Also known as Mt-SSB|OPA13|SOSS-B1|SSBP|mtSSB
Coordinate chr7:141738321-141750488
Strand +
Gene summary SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SSBP1P4
Bonobo Pan paniscus SSBP1P4
Gorilla Gorilla gorilla SSBP1P3
Orangutan Pongo abelii SSBP1P4
Gibbon Nomascus leucogenys SSBP1P2
Green monkey Chlorocebus sabaeus SSBP1P1
Crab-eating macaque Macaca fascicularis SSBP1P2
Rhesus Macaca mulatta SSBP1P3
Baboon Papio anubis SSBP1P3
Golden snub-nosed monkey Rhinopithecus roxellana SSBP1P3
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SSBP1P4
GTTTGGAAGACCTGGGTCTGAAACAGCTAGCCATTTGGTTCTTTAAAGATCCCTGAATGATGTGAGTTACTTGGGCGAGTGGGTCAGGACCCTGTTATGAGGCAGGTGATGGAAAAAATCCATTCACAATATTTTCTCTAGCAACAAGCCAGATATGGTGATCAGGGGACTGTGAAGTTTACCAAATGGGGGATGTCAGTCAAAAGAAAACATGGCATAGATTATCAGTATTCTGGCCAGGCCTCAGAGATGTGGCATAGCAGTATGTGAAAAAGGGATCTTGAGTTTATGTGGAAGGGCAAGTAGACTATGGTGAATATATGGATAAAAATAATGTGAGGTGGCAAGCAATGACTATCATAGCTGATAATATTATACTTCTAAGAGACCAGGCAAAAGAGAAGGCGTGGAATGGATGATTCTTCTTTGGCCATCATTTGGTACAGCCTCATTTCCAAATCATATATAATCTTTATAGTTCCCAATGACAAGAATTAAAATACTCTTA
>NM_001256512.1_2
CTGTTTCCTTTTTCCTCTGGCGAGCTTTGCGTTCCCTGTGCGCCGGAAGTGATCCCCTGCGTGGCTGGGCTGCTCGGGTTAGATCGTCAGGTGAGGGAGGAAGGGATAGCCAGCGCGAAGGAAGTGCTGGAGTCGTGTGTTTTGGCTGCGCGTGATCCTGCGTGGGTCGGGAGGTGTTTCTGTGTAGGTGTCTGGCCCTTTCATCAGTCGTGCGGAGGACCGCGTGATTTCCTTCCAGTTCTCCTCGGTTTTCAGGAAAAGCCTAAAGATTAGACTGTAAGAAAAGAAAATAGAAGCCATGTTTCGAAGACCTGTATTACAGGTACTTCGTCAGTTTGTAAGACATGAGTCCGAAACAACTACCAGTTTGGTTCTTGAAAGATCCCTGAATCGTGTGCACTTACTTGGGCGAGTGGGTCAGGACCCTGTCTTGAGACAGGTGGAAGGAAAAAATCCAGTCACAATATTTTCTCTAGCAACTAATGAGATGTGGCGATCAGGGGATAGTGAAGTTTACCAACTGGGTGATGTCAGTCAAAAGACAACATGGCACAGAATATCAGTATTCCGGCCAGGCCTCAGAGACGTGGCATATCAATATGTGAAAAAGGGGTCTCGAATTTATTTGGAAGGGAAAATAGACTATGGTGAATACATGGATAAAAATAATGTGAGGCGACAAGCAACAACAATCATAGCTGATAATATTATATTTCTGAGTGACCAGACGAAAGAGAAGGAGTAGAAAGGATGATTCTTCTTTGGCCATCATTTGGTACAGTCTCATTTCCAAGTCATGTATAATCTTTATGGCTTCCAAGGACAAGAATTAAAATACTCTTTTACGTAAAATGAGTAATAATCTTTTTTCTGACTGTC

Publications

PMID - Link Title