Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ZNF723P3
Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr19). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:42336178-42336892  UCSC
Coordinates (T2T) chr10:43213762-43214476  UCSC
Coordinates (hg19) chr10:42831626-42832340  UCSC
Strand -
Parental Sequence XM_024451653.1
Parental seq. overlap 586 bp
Parental seq. overlap (%) 17.6%
Genomic Region Intergenic
Retrocopy Summary ZNF723P3, located on chr10:42336178-42336892, is a retrocopy of the parental gene ZNF723. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ZNF723
Full Name zinc finger protein 723
Also known as ZNF723P
Coordinate chr19:22820075-22859398
Strand +
Gene summary Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Bonobo Pan paniscus LOC103783565P5
Gorilla Gorilla gorilla LOC101145569P2
Orangutan Pongo abelii LOC100451404P3
Gibbon Nomascus leucogenys LOC100585566P4
Marmoset Callithrix jacchus LOC100400163P3
Panda Ailuropoda melanoleuca SUMO2P10
Cat Felis catus LOC101085512P7
Chimpanzee Pan troglodytes Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ZNF723P3
AAGAGAATTCATAATGAAGAGAAACCCTACAAATGTGAAGAATGTGATAAAGCCTTTTACTGGTCCTTAAGCTTTACTAAACGTAAGATAGTTCATACTGGAGAGAAGCACTACAAATGTCAAGAATACGTCAAAGCTTTTAAGCGTCTTCAAACCTTACTATACATAAGAGAATTCATACTGGAGAGAAACCCTACAATTGTGAAAAATGTGGCAAAGCCTTTTACTGTTCCTCACACCTTATTCAACATAACATAGTTCATACTGAAGAGAAACACTACAAATGTCAAGAATGTGGCAAAGCTTTTAAGAAGTCTTTAGACCTTAATGTACATAAGATAATTCATAGTGGAGAGAAACCCTACAGATATGAAGAATGTGGCAGTCTTTAAACAATCCTCAAACCTGAATGAACGTAAGATAACTCATAGTGGAGAGGAATCCTACAAATGTGAAGAATGTGGCAAAGGCTTTAAACAATCCTCAAACCTGAATGAACATAAGATAACTCATAGTGGAGAGGAATCTTACAAATGTGAAGAATGTGGCAAAGGCTTTTACTGTTCCTCAAGCCTTACTAAGCATAAGATAGTTCATACTGAAGAGAAACCATACAAATGTGAAGAATGTGGCAAAGCTTTTAAGTGGTCCTCTGAACTTACTATACATCAGAGAATTCATACTGAAGAGAAACCCTGTAAATGTGAAGAATGTA
>XM_024451653.1
tcctattttatccagcccccacatatttttagtattctgatacatggctgggcccaacacctaggggttggaaatctcctttctctgccatgctcacagtggacctcatgacatatctctgcacgtgtcacttaaaagatgtgacccttttctgcctgcacgctgcccataggaaaaattgtgaaatactcatgggcccccaaaccaggtggtgtgtctctcctgcctaggccttgttcacagggagaattgtgacatatcactggactcagcacccaagtgatttgactctgctgcctgtgccctgctttcattagaggatattcacatatccctggcagaaaaccagatgatgtgactcttcttccgggtcccttctctcagagaatattataatatattcctgactcaagacccaggaatacagtccaccattaagacggtgactcatgtacttggaccaaacataaagaaggtcttgactttcatacctggagccagaaaatgtatggaattttgaatctcatttctggacctgcttgcaggcgtgattgtgacatataccttggtccagcacctgagtgatttgactatcctgcctgggtaaagcctcaaaatggaattgtgacacatgcctggtgcaagcatctaaggtgtgattgtggcatatgtctttgcccataccctgagtgattttagtttcctgcctgagcccagcccatagatggaattgtgacatataccaaggccaagcaccaaggccttgcctacaagaaagattgtgtcatatcactgagcccagcacctatgtgatgtacttcttctgccatagttctccccacataagacactgtgacatatttctgggccaattacataagttaaatgagtctttgcttatgcctggatctcaccctcagaagaacttatgacatgttgctggacccagcacctagctacaggtgggattgtgacatatgcctgggacgtggtcactggtacaatgatgacacccacaaacttcaacccacaaaccaggagaaatattgattctgtctgctaggctttgggcaacaggtggggtagtgactcttgagaaagaattcaacatgccggtgagcctgtgactttcataccaggacaccgtccttgggtgggattgggactctcattcacagatccgatatatcattgaaatgGGACCATTGACATTCACAGATGTGGCAATAAAATTTTCTCTGGAGGAGTGGCAATTCCTGGACACTGCACAGCAGAATTTATATAGGGATGTGATGTTAGAGAACTACAGAAACCTGGTCTTCCTGGGTGTTGGTGTCTCTAAGCCAGATTTAATCACCTGTCTGGAGCAAGGAAAAGAGCCCTGGAATATGAAGAGACACAAGATGGTAGCCAAGCCCCCAGTTGTGTGTTCTCATTTTGCCCAAGACCTTTGGCCAGAGCAGGGCATAAAAGATTCTTTCCAAAAAGTAATACTGAGAAGCTATGGAAAATATGGACATGACAATTTACAATTAAGAAAAGGCTGTGAAAGTGTGGATGAGTGTAAGATGCACAAAGGAGGTTATGATGAACTTAAGCAATGTTTGACAACTACCCCGAGCAAAATATTTCAATGTGATAAATATGTAAAAGTCTTTCATAAATTTTCAAGTTCAAATAGCCAGAAGATAAGACATACTGGAAATAATTCTTTCAAATGTAAAGAATGTGGCAAATCATTTTGCATGCTTTCACACCTAACTAAACATGAAAGAAATCATACTAGAGTGAATTGTTACAAATGTGAAGAATGTGGCAAAGCCTTTAGTGTGCCCTCAAAGCTTAATAATCATAAGAGAATTCATACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCCTTTAATGTGTCCTCAAGCCTTAATAATCATAAGAGAATTCATACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAACCTTTAATATGTTCTCAAGCCTTAATAATCATAAGAGAATTCACACTGGAGAGAAACCCTACAAATGTAAAGAATGTGGCAAAGCCTTTAATGTGTTCTCAAGCCTTAATAATCATAAGAGAATTCATACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCCTTTAACCAGCCCTCACACCTTGCTACACATAAGAGAATTCATACTGGAGAGAAACTCTACAAATGTGAAGAATGTGGCAAAGCATTCAGCCAGTCCTCACACATTACTACACATAAGAGAATTCACACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCTTTTAAAGTATCTGTACACCTTACTACACATAAGAGAATTCATACTGGAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCCTTTAACCAATCCTCAGCCCTTACTACACATAAGATAATTCATACTGGAGAAAGACCTTACAAATGTAAACAATGTGGTAAAGGTTTTAGCCAATCCTCAACCCTTACTAAACATAAGATAATTCATACTAAAGAGAAACCCTACAAATGTGAAGAATGTGGCAAAGCTTTTAACCAATATTCAACCCTTAATAAACATAAGATAATTCATGCTAGAGAGAAGCCTTACAAATGTGAAGAATGTGGCAAAGCCTTTAACAAGTCCTCAATTCTTAACAGACATAAGATAATTCATACTAAAGAGAAATCACAGAAATGTGAAGAATATGAGAAAGCCTTTAAATGGTTGTCTCACTTGATTGTAGGTAAGATACTTTATACTGGAGAAAACTCCTACAAGTGTGAAGAATGTGGCAAAACTTTTGACTAATGCTCACACCTTGGTGCACAGGAAATAATTTATATTTTAGACAACTTGTACAAGTATAAAGAATGTGACGAAGCCATTAATAACTGCTCACATTTTAACATCAGAGAGCTAATACAAGCATTAAAGGTGCAATTACTGTCAAAAGATCTTCCAGAAAATATAAGCCTTTAAAATGTATTAAATTTATTGCTGTAAATTCTTATGTCTTACAGTTCAGAATCTCTTCATGCAAATTCTGTTTTTACTTTTCTAGTACTCATACTAGACCCATAATTTTCTTGATTCTTATTTCGTTTTGTTTTATAGGTTATAAAGTATTCATTATATTAGCTGGTCAGTGATTATAGTAATTGTTTTTATGAAATTTAGTAGTGCACACAAAATAATTTTCAAAGGTAATTCCATTAGTGTATTAAGTTTTATTTAGTGTTAGAACATTCCATTTTGTTCTTTTAAGTGCAGAAACTTATATAAG

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