Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name FXYD6P1
Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:42555365-42555989  UCSC
Coordinates (T2T) chr10:43432912-43433536  UCSC
Coordinates (hg19) chr10:43050813-43051437  UCSC
Strand +
Parental Sequence NM_022003.4
Parental seq. overlap 513 bp
Parental seq. overlap (%) 30.2%
Genomic Region Intergenic
Retrocopy Summary FXYD6P1, located on chr10:42555365-42555989, is a retrocopy of the parental gene FXYD6-FXYD2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name FXYD6-FXYD2
Full Name FXYD6-FXYD2 readthrough
Also known as FXYD6
Coordinate chr11:117820057-117876658
Strand -
Gene summary This locus represents naturally occurring read-through transcription between the neighboring FXYD domain-containing ion transport regulator 6 (GeneID 53826) and sodium/potassium-transporting ATPase subunit gamma (GeneID 486) genes on chromosome 11. One read-through transcript produces a fusion protein that shares sequence identity with each individual gene product, while another read-through transcript encodes a protein that has a distinct C-terminus and only shares sequence identity with the upstream locus (GeneID 53826). [provided by RefSeq, Aug 2011]

Homology

Species Scientific Name Retrocopy
Gorilla Gorilla gorilla FXYD6P1
Orangutan Pongo abelii FXYD6P2
Green monkey Chlorocebus sabaeus FXYD6P2
Crab-eating macaque Macaca fascicularis FXYD6P2
Rhesus Macaca mulatta FXYD6P1
Baboon Papio anubis LOC101011037P1
Golden snub-nosed monkey Rhinopithecus roxellana FXYD6P2
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gibbon Nomascus leucogenys Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>FXYD6P1
TGCCACTCCCAGCCTCCTTGGGACTTGACACATCCTCCTGGGATCATCTCAGATGGGACTGACTGTGCCGGCACCATGGAGGTGGTGCTGATCTTTCTATGCAGCCTGTTGGCCCACATTGTCCTGGCCGATGCAGTTGAGAGGGAGAAGCAAATTGACCCTTTTCATTATGACTACCAGACCCTGAGGATTAGGGGGTTGGTATGTGCTGTGGTCCTCTTCTCCATTGGGATCCTCCTTATCCTAGGTTGCAGATGCAAGTGCAGTTTCAATCAGAAGCCCAGGACCCCAGGAGAGGAGGAAGCCCAGGTGGAGAACCTCATCACTGCAAATGCAACAAAGCTCCAGAAAGCAGAGAGCTGAATGAAGTGCAGCCTTCCAGTGGGAAGCCTCTGGAACCTGAAGGCAGCTGCTTGAACTTTTAGATGCAAATGTTGATGCTTAAGAAAACAGCCACTTCAGCAACAAATCTTTCCCCAAGAGAAGCCAATAACTTGTGTGTCCCCCCATGCCCTTCCCTGTCCCTTCTAACACCATTCCTCCACCTGATGATCCAACTAATCTCTTGCCTCACCACTGCAGCCTGCAGGCTCCTCCAACTCC
>NM_022003.4
GCCACTCCCAGGCTCCTCGGGACTCGGCGGGTCCTCCTGGGAGTCTCGGAGGGGACCGGCTGTGCAGACGCCATGGAGTTGGTGCTGGTCTTCCTCTGCAGCCTGCTGGCCCCCATGGTCCTGGCCAGTGCAGCTGAAAAGGAGAAGGAAATGGACCCTTTTCATTATGATTACCAGACCCTGAGGATTGGGGGACTGGTGTTCGCTGTGGTCCTCTTCTCGGTTGGGATCCTCCTTATCCTAAGTCGCAGGTGCAAGTGCAGTTTCAATCAGAAGCCCCGGGCCCCAGGAGATGAGGAAGCCCAGGTGGAGAACCTCATCACCGCCAATGCAACAGAGCCCCAGAAAGCAGAGAACTGAAGTGCAGCCATCAGGTGGAAGCCTCTGGAACCTGAGGCGGCTGCTTGAACCTTTGGATGCAAATGTCGATGCTTAAGAAAACCGGCCACTTCAGCAACAGCCCTTTCCCCAGGAGAAGCCAAGAACTTGTGTGTCCCCCACCCTATCCCCTCTAACACCATTCCTCCACCTGATGATGCAACTAACACTTGCCTCCCCACTGCAGCCTGCGGTCCTGCCCACCTCCCGTGAtgtgtgtgtgtgtgtgtgtgtgtgtgactgtgtgtgtTTGCTAACTGTGGTCTTTGTGGCTACTTGTTTGTGGATGGTATTGTGTTTGTTAGTGAACTGTGGACTCGCTTTCCCAGGCAGGGGCTGAGCCACATGGCCATCTGCTCCTCCCTGCCCCCGTGGCCCTCCATCACCTTCTGCTCCTAGGAGGCTGCTTGTTGCCCGAGACCAGCCCCCTCCCCTGATTTAGGGATGCGTAGGGTAAGAGCACGGGCAGTGGTCTTCAGTCGTCTTGGGACCTGGGAAGGTTTGCAGCACTTTGTCATCATTCTTCATGGACTCCTTTCACTCCTTTAACAAAAACCTTGCTTCCTTATCCCACCTGATCCCAGTCTGAAGGTCTCTTAGCAACTGGAGATACAAAGCAAGGAGCTGGTGAGCCCAGCGTTGACGTCAGGCAGGCTATGCCCTTCCGTGGTTAATTTCTTCCCAGGGGCTTCCACGAGGAGTCCCCATCTGCCCCGCCCCTTCACAGAGCGCCCGGGGATTCCAGGCCCAGGGCTTCTACTCTGCCCCTGGGGAATGTGTCCCCTGCATATCTTCTCAGCAATAACTCCATGGGCTCTGGGACCCTACCCCTTCCAACCTTCCCTGCTTCTGAGACTTCAATCTACAGCCCAGCTCATCCAGATGCAGACTACAGTCCCTGCAATTGGGTCTCTGGCAGGCAATAGTTGAAGGACTCCTGTTCCGTTGGGGCCAGCACACCGGGATGGATGGAGGGAGAGCAGAGGCCTTTGCTTCTCTGCCTACGTCCCCTTAGATGGGCAGCAGAGGCAACTCCCGCATCCTTTGCTCTGCCTGTCAGTGGTCAGAGCGGTGAGCGAGGTGGGTTGGAGACTCAGCAGGCTCCGTGCAGCCCTTGGGAACAGTGAGAGGTTGAAGGTCATAACGAGAGTGGGAACTCAACCCAGATCCCGCCCCTCCTGTCCTCTGTGTTCCCGCGGAAACCAACCAAACCGTGCGCTGTGACCCATTGCTGTTCTCTGTATCGTGATCTATCCTCAACAACAACAGAAAAAAGGAATAAAATATCCTTTGTTTCCTA

Publications

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