Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CAP1P2
Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:43603779-43606293  UCSC
Coordinates (T2T) chr10:44484701-44487215  UCSC
Coordinates (hg19) chr10:44099227-44101741  UCSC
Strand -
Parental Sequence NM_001350476.2
Parental seq. overlap 2377 bp
Parental seq. overlap (%) 91%
Genomic Region Intergenic
Retrocopy Summary CAP1P2, located on chr10:43603779-43606293, is a retrocopy of the parental gene CAP1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CAP1
Full Name cyclase associated actin cytoskeleton regulatory protein 1
Also known as CAP|CAP1-PEN
Coordinate chr1:40040240-40072648
Strand +
Gene summary The protein encoded by this gene is related to the S. cerevisiae CAP protein, which is involved in the cyclic AMP pathway. The human protein is able to interact with other molecules of the same protein, as well as with CAP2 and actin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CAP1P2
Bonobo Pan paniscus CAP1P2
Gorilla Gorilla gorilla CAP1P2
Orangutan Pongo abelii CAP1P3
Gibbon Nomascus leucogenys CAP1P2
Green monkey Chlorocebus sabaeus CAP1P1
Crab-eating macaque Macaca fascicularis CAP1P1
Rhesus Macaca mulatta CAP1P1
Baboon Papio anubis CAP1P1
Golden snub-nosed monkey Rhinopithecus roxellana CAP1P1
Marmoset Callithrix jacchus CAP1P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CAP1P2
GGAAGTGGAGAGCGGCTGATCGCAGTCGGGAGGTGATACATTATGACTGACATGCAAAATCTGGTAAAAAATTGGACAGGGCAGTGGGCCGCCTGGAGGCAGTATCCCATACCTCTGACATGCACCGTGGATATGGAGATAGTCCTTCAAAAGCAGGAGCAGCTCCATATGCGCAGGCATTTGACTCGCTGCTTGCCTGCCCTGTGGCAGAGTACTTGAAGATCAGTAAAGAGATTGGGGAAGACGTGCAGAAAGATGTGGAGATGGTACACACAGTTTTGAAGTTGGAGTGAGCTCTCTTGGTTACAGCTTCTCAGTGTCAATAGCCGGCAGGTAATAAGCTTTCCGATCTGTTGGCACCTATCTCAGAGCAGATCAAAGAAGTGATAACCTTTTGGGAGAAGAACCGAGGCAGCAAGTTGTTTAATCAGCTGTCAGCTGTCAGTGAAAGTATCCAGGCCCTAGGCTGGGTGGCTATGGCTCCCAATCCTGGCCCTTATGTGAAAGAAATGAATCATGCTGCTGTGTTTTATACAAACTGAGTCCTTAAAGAGTACAAAGATGTGGATAAGAAGCATGTAGACTGAGTCAAAGCTTATTTAAGTATATGCACAGAGCTGCAGGCTTACATTAAGGAGTTCCATACCACCGGACTGCCTGGAGCAAAACGGGGCCTGTGACAAAAGAACTGAGTGGACTGCCATCTGGACCCTCTGCTGGATCAGCTACTCCTCCCCCACCACCAGGCCCCCCTCCTCCACTAGTCTCTGTCAGTTCAGGCTCAGATGAGTCCGCTTCCCTCTCAGCACTGTTTGCGCAGATTAATCAGGGGGAGAGCATCACACATGCCCTGAAACGTGTATCTGATGACATGAAGACTCACAAGAACCCTACCCTGAAGGCTCAGAGTGGTCCAGTACGCAGTGGCCCCAAGCCATTCTCTGCACCTAAACCCCAAACCAGCCACAAAGAAGGAGCCAGCTGTACTTGAACTGGAGGGCAAGAAGTGGAGAGTGGAAAATCAGGAAAATGTTTCCAATCTGGTGATTGATGACACAGAGCTGAAACAGGCGGCTTACATATACAAGTGTGTCAACACGATGTTGCAAATCAAGGGCAAAATTAACTCCATTACAGTAGATAATTGTAAGAAACTTGGTCTGGTATTCGATGATATGGTGGGCATTGTGGAGATAATCAACAGTAGGGATGTCAAAGTTCAGGTGATGAGTAAAGTGCCAACCATTTCCATCAACAAAACAGATGGCTGCCATGCTTACCTGAGCAAGAATTCCCTGGATTGTGAAATAGCCAGTGCCAAATCTTCTGAGATGAATGTCCTCATTCCTACAGAAGGCGGTGACTTTAATGAATTCCCAGTTCCTGAGCAGTTCAAGACCCTCTGGAATGGGCAGAAGTTTGTCGCCACAGTGACAGAAATTGCTGGATAAGCGAAGTGCCACTGGGTTCTTTGCCCTCCCTTCACACCATGGGATAAATCTGTATCAAGACGGTTCTTTTCTAGATTTCCTCTACCTTTCTGCTCTTAAAACTGCTTCTCTGCTCTGAAAAGCACAGCTACCTGCCTTCACTGAAATATACCTCAGATGTGCAGTGGGATAGCAGGTCAGTTGATCTTCTGCAGGAAGGTGCAGCTTTTCCAAATCAGCTCAACTGCCGACGAGGACTAATGATGCATTTTAGCTTTGAGCTTTGGGGGTTATTCTACCAACAAACAGTCCACTGGGAAGAAAACAGTCCCAGGAATTAACAGATCAGAACGTTCACACTGGTTAATCTTTTTCTGACAATGAGCATGAAGGTAGCAGAAGCTGGTGTGTTTCCAGATGGTTCTTCTAACCAAACTAATTTTTCACTATTGACAAGTGAGGCAAGGATTGCACTGGACCAAAGGCTGAGGCTTGGCCATCTAGCATTCCACGCAAAATTGTTTCCTATAAGCATTCCTTTTATTCACTATTCTATCCTGGGTCTGCCTCAACCATGAGATAGGAGAGTCTCCGGTACTAGCTGCTGTAGCAGTGCCCTTCATCCAGGGCAGTTAAAGGAGTATTCAACCCTTTCTTTCTCTGGGATCCCTGCCCAGCACCTTCCTACAGAGATGAAAAAAAAAAAAAGGAAAAACAACACTCCATTCCAAGGAGTCTGGTATTCCTGAATCCTCCTTCCCTGCTAGGTGCCTGTCACCTGTCTTCACTGCCTCCTTTTCCCTGTCACACTCACCAGCTTATGGCTTCTGTCCAAGCACCTGAACAGGGGACCAAAACCTCCACTGCAAGCTGCTTTTAGGTCTTGATTTATGTAAGAATCTTGCACAGCACTGCTAATGTAAATTTCAGTTTTTTCCCTCTAGGACAAACACTTACCAAAATACGCAACTTTTTTGGTGGGAAGAGAGATTGTCCTGTGATTTCTACCCATTTCCTGATCCTGTGGAAATAAATCTTTATGTACTTAAAGTTATACAGAAAATAGAATGAAATAAATACCAAAA
>NM_001350476.2
GAGATTGCTGGGCGGTTCTTGCCGGAAGCGGAGAGCGGCTGATCGCAGTCCGGAGCAGGTGGTCCATTATGGCTGACATGCAAAATCTGGTAGAAAGATTGGAGAGGGCAGTGGGCCGCCTGGAGGCAGTATCTCATACCTCTGACATGCACCGTGGGTATGCAGACAGTCCTTCAAAAGCAGGAGCAGCTCCATATGTGCAGGCATTTGACTCGCTGCTTGCTGGTCCTGTGGCAGAGTACTTGAAGATCAGTAAAGAGATTGGGGGAGACGTGCAGAAACATGCGGAGATGGTCCACACAGGTTTGAAGTTGGAGCGAGCTCTGTTGGTTACAGCTTCTCAGTGTCAACAGCCAGCAGAAAATAAGCTTTCCGATTTGTTGGCACCCATCTCAGAGCAGATCAAAGAAGTGATAACCTTTCGGGAGAAGAACCGAGGCAGCAAGTTGTTTAATCACCTGTCAGCTGTCAGCGAAAGTATCCAGGCCCTGGGCTGGGTGGCTATGGCTCCCAAGCCTGGCCCTTATGTGAAAGAAATGAATGATGCCGCCATGTTTTATACAAACCGAGTCCTCAAAGAGTACAAAGATGTGGATAAGAAGCATGTAGACTGGGTCAAAGCTTATTTAAGTATATGGACAGAGCTGCAGGCTTACATTAAGGAGTTCCATACCACCGGACTGGCCTGGAGCAAAACGGGGCCTGTGGCAAAAGAACTGAGCGGACTGCCATCTGGACCCTCTGCCGGATCATGtcctcctccccctccaccatgcccccctcctcccccAGTCTCTACCATTTCATGCTCATATGAGTCTGCTTCCCGCTCATCACTGTTCGCGCAGATTAATCAGGGGGAGAGCATTACACATGCCCTGAAACATGTATCTGATGACATGAAGACTCACAAGAACCCTGCCCTGAAGGCTCAGAGTGGTCCAGTACGCAGTGGCCCCAAACCATTCTCTGCACCTAAACCCCAAACCAGCCCATCCCCCAAACGAGCCACAAAGAAGGAGCCAGCTGTACTTGAACTGGAGGGCAAGAAGTGGAGAGTGGAAAATCAGGAAAATGTTTCCAACCTGGTGATTGAGGACACAGAGCTGAAACAGGTGGCTTACATATACAAGTGTGTCAACACGACATTGCAAATCAAGGGCAAAATTAACTCCATTACAGTAGATAACTGTAAGAAACTTGGCCTGGTATTCGATGACGTGGTGGGCATTGTGGAGATAATCAACAGTAAGGATGTCAAAGTTCAGGTAATGGGTAAAGTGCCAACCATATCCATCAACAAAACAGATGGCTGCCATGCTTACCTGAGCAAGAATTCCCTGGATTGTGAAATAGTCAGTGCCAAATCTTCCGAGATGAATGTCCTCATTCCTACAGAAGGCGGTGACTTTAATGAATTCCCAGTTCCTGAGCAGTTCAAGACCCTATGGAACGGGCAGAAGTTGGTCACCACAGTGACAGAAATTGCTGGATAAGCGAAGTGCCACTGGGTTCTTTGCCCTCCCTTCACACCATGGGATAAATCTGTATCAAGACGGTTCTTTTCTAGATTTCCTCTACCTTTTTGCTCTTAAAACTGCTTCTCTGCTCTGAGAAGCACAGCTACCTGCCTTCACTGAAATATACCTCAGGCTGAAATTTGGGGTGGGATAGCAGGTCAGTTGATCTTCTGCAGGAAGGTGCAGCTTTTCCATATCAGCTCAACCACGCCGCCAGTCCATTCTTAAGGAACTGCCGACTAGGACTGATGATGCATTTTAGCTTTGAGCTTTTGGGGGTTATTCTACCAACAAACAGTCCATTGGAAAGAAAACAGTCCCTGGAATTAACAGATCAGAATGTTCACACTGGTTAATCTTTTTTTAACAATGAGCATGAAGGTAGCAGAAGCTGGTGTGTTTCCAGATGGTTCTTCTAACCAAACTAATTTTTCACTGTTGACAAGCGAGGCAAGGGTTGCACTGGACCAAAGGCTGAGGCTTGGCCATCTAGCATTCCATACAAAATTGTTTCCTATAAGCATTCCTTTTATTCTCTATTCTATCCTGGGTCTGCCTCAACCGTGAGATAGGAGAGTCTCTGGTACTAGCTGCTGTAGCAGTGCCCTTCATCCAGGGCAGTTAATGGAGTCTTGGACCCTTTCTTTCTCTGGGATCCCTGCCCAGCACCTTCCTATAGAGATGACTTTaaaaggaaaaaaaaaaaaaaaaaaaCCCACATGATTTCAAGGAGTCTGGCATTCCTGAATCCTTCTTCCCTGCCAGGTGCCTGTCACCTGTCTTCACTGCCTCCTTTTCCCTGTCATGCTCATCAGCTTATGGCTTCTGTCTAAGCACCTGAACAGAGGACTGAAACCTCCACTGCAGGCTGGTTTTAGGTCTTGAATTATGTAAGAATCTTGCACAGCACTGCTAATGTAAATTTCAGTTGTTTTTCCCTCTAGGACAAACACTTACCAAAATATGCAACTTTTTTTTGGTGGGAAGAGAGATTGTCCTGTGATTTCTACCCATTTCCTGAGGCCTGTGGAAATAAACCTTTATGTACTTAAAGTTATACAGAAAATAGAATAAAGTTAATACCAAACTTG

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