Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name SLC9A3P3
Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr5). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:50025093-50027024  UCSC
Coordinates (T2T) chr10:50874729-50876660  UCSC
Coordinates (hg19) chr10:51784853-51786784  UCSC
Strand -
Parental Sequence NM_001284351.3_2
Parental seq. overlap 1585 bp
Parental seq. overlap (%) 28.5%
Genomic Region Intergenic
Retrocopy Summary SLC9A3P3, located on chr10:50025093-50027024, is a retrocopy of the parental gene SLC9A3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name SLC9A3
Full Name solute carrier family 9 member A3
Also known as DIAR8|NHE-3|NHE3
Coordinate chr5:470456-524449
Strand -
Gene summary The protein encoded by this gene is an epithelial brush border Na/H exchanger that uses an inward sodium ion gradient to expel acids from the cell. Defects in this gene are a cause of congenital secretory sodium diarrhea. Pseudogenes of this gene exist on chromosomes 10 and 22. [provided by RefSeq, Mar 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes SLC9A3P1
Bonobo Pan paniscus SLC9A3P1
Gorilla Gorilla gorilla SLC9A3P2
Orangutan Pongo abelii SLC9A3P1
Gibbon Nomascus leucogenys SLC9A3P1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>SLC9A3P3
GGCTCATGGGCAACCTGCAGATAGGGCTGCTGGACTTCCTCCTGTTCGGCAGCCTGATCACCACTGTGGACCCAGCAGCCATACTGGTTGGGTTTGAGGAAGTTCATGTCAATGAGGTCCTGTTCATCATCATCTTCAGGGAGTTGCTACTGAATGACTGTACAATGTGTTTCAATCTTTTGTGACACTGGATGATGAGAACATGATCAGCGTGGACCATGCCAAAAGTGTAGTGTCCTTTGTGGTGAGCCTGGGGGGCATGACTGTGGGGTGGTCTTTGCCTTCCTGCTGTCACTGGTGACCCACTTCACCAAGCATGTGCACATCATCTAGCCTGGTTTTGTGTTAGTCATCTCCTACCCGTCCATAGGACGTCTGAGAAGCTGTTGCTGTTGGCCATCCTGGCCATTATCTTCTGTGGCATCTGCTGTCATAAGTACATGAAGGCCAACATCTTGGAGCAGTCGGCCAACACCATGCACTACACCGTGAAGATGCTGGCCAGTGGTGTCAATACAATCTTCATATCCCTGGGCATCTCGGTCATGAACCTGCTCATCTGGACGTGGAACATGGCCTTCATCCTCCTGCACTGGCCTACACCTTCATGTACCGAGCCATGGTGTCATCCAGTCCTGACTCCTGTAGTGCTATTGGATGATGCAGCTGGAGATCATAGACCAGGTGGTCATGTCCTATAGAGGCCTGCATGGGGCCATGGCCTTCATCCTGGTCATGCTTCCGGACAGAAACAAGGTCAAGGAGAAGAACCTGTTTGTCAGCACCACCGTCATCATCTTCTTCACAGTCATTTTCCAGGGGCTGACCATCAAGTCCCTGGTGCAGTGGCTGAAGGTGAAGAGGAGTGAGCACCAGGAGCCCAAGCTCCATGAGAAGCTGCACCACCATGCTTTCAACCACATCCTCTTGGCCATCAAGGACATATCCCGGCATATCAGGCACAACTATCTCAGAGAGATGTGGTCCCACTTTGACAGGAAGTTCCTCAGTGGGGTTCTCATGAGAATGCTGGCCCAGAAGTCTCCATATGGGATCCTCAATGTCTTCCATGAGCTGAACCTGAAGGATGCCATCAGCTAAGCCACCAAAGGAGAGTGCCTAAGGTCCGTGGCCTTCATCAGCTCCCCAAGTACTGATAACGTCGTCAACATGGACTTCACGGCACGATTGTCCACCATGGTGGCCTCTGTCTCCTACCTTCTGAGGGAGAACATCAGTGCCGTCTGTCTGGACGTTCAGTCCCTGGAGCAGTGTGGCAGAGCATTCCGTATGGGGAGGACCCCGTCACGCACCACACGCTGCAGCAGTACCTGTGCAAGCCGGGGAAGGAGTACATGCATCGCTACAGCCACACCAACTGAGGACAAGAAGCGGGACCGGGAAATCTTCCACAGGTCCATGAGGAAGCACCTGGAGTCCTTCAAGTTGAGCAAGCTCAGGATCAACCAGAACAAGAAGGCAGCCAAGCTGTACAAGCCAAAGAGCGCCCAGAAGCGGTAAAACAGCAGCATCCCCAATAGGAAGCTGCCCAGGTAGAGCCCCGTGCACAATTTCACCATTCAGGAGAAAGACTTGCAAATTTCAGACACGGAGGAGGCCCCCAACTATGATGCTGAGGAGACGAGGGAGGGGGGTGGTGTCAGGGCGAGTACTGAGACCCCAGCCTCGTCGCCAGAGTGCCACCCTGGCTGTCTCCTGGGGAGATGGTGGTGTCCTCACAGAGGGCCTGCGTGCAGATCCCCCACTCTCCTGGCACTTTCCGCTGCCTGACGCCCTTGCAGCTCAGCTACAAGTCGGTGGACTCATTCCTGCAGGCAGATGGCCCCAGGGAGCGACCCCAGGCTGCCTTCCCCTAGTGCACGCACATGTGACACCGGCTCTGACATGCCCCTGACTGGACGCTTGTCCCCA
>NM_001284351.3_2
GGACTGTAGCCGGTACCGGCACCGGAGCGCGCCGGGTCCTCGCCGGGTCCCAGCCCCGCGCGTCGGCCCAGCCCAGCCGGGACCCCCCGCGACATGCGCGTCCCAGCCCTGCGCTGAGCAGGCGGCAATGTGGGGACTCGGGGCCCGGGGCCCCGACCGGGGGCTGCTGCTGGCGCTGGCGCTGGGCGGGCTGGCGCGGGCCGGGGGCGTCGAGGTGGAGCCCGGCGGCGCGCACGGCGAGAGCGGGGGCTTCCAGGTGGTCACCTTCGAGTGGGCCCACGTGCAGGATCCCTACGTCATCGCGCTCTGGATCCTCGTGGCCAGCTTGGCCAAGATCGGGTTCCACCTGTCCCACAAGGTCACCAGCGTGGTTCCCGAGAGCGCCCTGCTCATCGTGCTGGGCCTGGTGCTGGGCGGCATCGTCTGGGCGGCCGACCACATCGCGTCCTTCACACTGACGCCCACCGTCTTCTTCTTCTACCTGCTGCCCCCCATCGTGCTGGACGCCGGCTACTTCATGCCCAACCGCCTCTTCTTCGGCAACCTGGGGACCATCCTGTTGTACGCCGTCGTGGGTACCGTGTGGAACGCGGCCACCACCGGGCTGTCCCTCTACGGCGTCTTCCTCAGTGGGCTCATGGGCGACCTGCAGATTGGGCTGCTGGACTTCCTCCTGTTTGGCAGCCTCATGGCGGCTGTGGACCCGGTGGCCGTCCTGGCCGTGTTTGAGGAGGTCCATGTCAACGAGGTCCTGTTCATCATCGTCTTCGGGGAGTCGCTGCTGAACGACGCAGTCACCGTGGTTCTGTACAATGTGTTTGAATCTTTCGTGGCGCTGGGAGGTGACAACGTGACTGGCGTGGACTGCGTGAAGGGCATAGTGTCCTTCTTCGTGGTGAGCCTGGGGGGCACGCTGGTGGGGGTGGTCTTCGCCTTCCTGCTGTCGCTGGTGACGCGCTTCACCAAGCATGTGCGTATCATCGAGCCCGGCTTCGTGTTCATCATCTCCTACCTGTCCTACCTGACGTCCGAGATGCTGTCGCTGTCGGCCATCCTCGCCATCACCTTCTGTGGCATCTGCTGTCAGAAGTATGTGAAGGCCAACATCTCGGAGCAGTCGGCCACCACCGTGCGCTACACCATGAAGATGCTGGCCAGCAGCGCCGAGACCATCATCTTCATGTTCCTGGGTATCTCGGCCGTGAACCCGTTCATCTGGACCTGGAACACGGCCTTCGTGCTCCTGACGCTGGTCTTCATCTCCGTGTACCGGGCCATCGGTGTGGTCCTGCAGACCTGGCTTCTGAACCGCTACCGCATGGTGCAGCTGGAGCCCATTGACCAGGTGGTCCTGTCCTACGGGGGCCTGCGCGGGGCCGTGGCCTTTGCCCTGGTGGTGCTTCTGGATGGAGACAAGGTCAAGGAGAAGAACCTGTTCGTCAGCACCACCATCATCGTAGTGTTCTTCACCGTCATCTTCCAGTGGCTGAAGGTGAAGAGGAGCGAGCACCGGGAACCTCGGCTCAACGAGAAGCTGCACGGGCGCGCTTTCGACCACATCCTCTCGGCCATCGAGGACATATCCGGACAGATCGGGCACAATTATCTCAGAGACAAGTGGTCCCACTTCGACAGGAAGTTCCTCAGCAGGGTCCTCATGAGACGGTCGGCCCAGAAGTCTCGAGACCGGATCCTGAATGTCTTCCACGAGCTGAACCTGAAGGATGCCATCAGCTACGTGGCTGAGGGAGAGCGCCGCGGGTCCCTGGCCTTCATCCGCTCCCCCAGCACCGACAACGTGGTCAACGTGGACTTCACGCCACGATCGTCCACCGTGGAGGCCTCTGTCTCCTACCTCCTGAGAGAAAATGTCAGCGCTGTCTGCCTGGACATGCAGTCTCTGGAGCAGCGACGGCGGAGCATCCGGGACGCGGAGGACATGGTCACGCACCACACGCTACAGCAGTACCTGTACAAGCCGCggcaggagTACAAGCATCTGTACAGCCGACACGAGCTCACGCCCACGGAGGACGAGAAACAGGACCGGGAAATCTTCCACAGGACCATGCGGAAGCGCCTGGAGTCCTTCAAGTCGACCAAGCTGGGGCTCAACCAGAACAAGAAGGCGGCCAAGCTGTACAAGCGGGAGCGTGCCCAGAAGCGGAGAAACAGCAGCATCCCCAATGGGAAGCTGCCCATGGAGAGCCCTGCGCAGAATTTCACCATCAAGGAGAAAGACTTGGAACTTTCAGACACCGAGGAGCCCCCCAACTATGATGAGGAGATGAGTGGGGGGATCGAGTTCCTGGCTAGTGTCACCAAGGACACAGCGTCCGACTCCCCTGCAGGAATTGACAACCCTGTGTTTTCTCCGGACGAGGCCCTGGACCGCAGCCTCCTGGCCAGGCTGCCGCCCTGGCTGTCTCCCGGGGAGACGGTGGTCCCCTCGCAGAGGGCCCGCACGCAGATTCCCTACTCTCCCGGCACCTTCTGCCGCCTGATGCCCTTCCGCCTCAGCAGCAAGTCCGTGGACTCCTTCCTGCAGGCAGACGGCCCCGAGGAGCGGCCCCCCGCCGCCCTCCCCGAGTCCACACACATGTGACACCGGCTCCGACACGCCGCTAACCGGCCGCTCGTCCCCGCGCCACGGTCCGCCCACCGCCGCCGCCGCTGTCCCAGAGAAACCCCAGATCCCCGCGCGGCTACAGCGACCGCGAGCCCCGAGCCCCGCCTCGCCCACGCCAGCGCCTGCGCAGAACTCCGAGAGTGCCGCGCCTGCGCCCGCAGAGCCGCCCGAGGGCGAGCCGGGGGCGGGGCCTGCGCCGGGGGCGGGGCCGGAGCGCCGAGGGCTGCCGAGTGCGCACGCGCGTTCGGCGGCGGCGCGCCGCGTGCACAGCCGGCGCTCGTTCCAGCGGCCTCGCGCGCGCCGCCGCCCCGCGCTGCTGAAGCTGGCGTCGCTGCCGCCCTCGTGCCACGCACCGCCGCACGCGCTGGAGCAGGAGGAGACGCCGCTGTGACGCCGCCGGCGGGAAGGGTCCGCGCGCCATGGCTGGCCGCTCGCGCCCTTTCCCACCGCTGCCGGGAAACCGAGGCTCGCCCCAAACGGATTTGCGTGAAACCAGCCCAAGGTTCCGGGCCCCCCCAACCGAGCCCCGCGCCCGGGGACTGACTCGGGGACCGACTCAGGGACCTCCCGAGCGCCAGGACTCAGGGCCCGACCTGCAGCGGCTGCAGGCCCAGCGCCCGCAAGCGGCCTGGGCCGAGCGCCGTTTCCAGGCCCTCGCCAGGTCTTTGAACTGCAGGTAAAGTGGCAGGAACGTCTTCCGTCTGCTCAGCGTTTGGGGATTTAGACTCCTAAAGCCAGTACCTGCCCCGTTTCCCCCCCAGGTTCCGTCCTGCCCGCGCCCGGTCTCAGGGTGGCGGCCCCGGACACGGCCCGTCCCCACAGACGAGGTCTCCGGCCTGAGCTGTCGCACCTGGCGCGGAGGTCGCCCGGGGTGCCCTGGCTGGGTGAGAGGTGGCCTGGCGGGCGGAGCTTGCCAAGAATCACGGCCAGTCCTTAAGTGGATGGTGGGGCCCAGCAGCTGCTCTGTCCCCCTTAACAAACCAGGGGGCATGGAGGGGCCCAGGGCACCGCCCCCCTACCAGGCTCAGGCCCTCCAAGGAGAACCTGCTGAgacccctgagcctgtcctagaccccggacccctgaccctTCCCACCCCTTCCAGCGTCCCAGGGCGAGGCCTTGGACAGAGCTCCTGGTCCTCTGCAGGGAGACCATCCAGCCCAAGCTCTGGGAGGCACAGTCCATTGAGTGGGCGGAGGCCGCGGGTGCTGAGCCGGGGAGGGTGCTCGGAGTCCATCCATCCCTCAGACGGCAAGTCCCACAGGGTCCAACCCACCTGAAACCTGCCTGCACGGTGGAAGTGGTGGAGGTGGACACTCCTAGGGGCTTTTCTAAAGCTAGACTCGCAGCTCCTTGCTCAGGAAAATTAAACTATTCACGTTTCAGATCAAGTGTTGACAGTCACCAGTCAGGAGGAGTTCTTAAAGAGTTTTATGTTGACTGAATATTGCACATTGAGTCCCCATTGAGTCCCTGGTGGGAAAAGTCCACAATTTCCCATTGATAGCTTTTTACTGTTGTGAAAAAGGGAAGCGTCAGCCACACAAAAGCCTGCATGACCGCTGCTTCGGAGAAGCTCTCGACCCTAACTGCAGTCACTGTTACTTGGATCAGATCAAGCGCAGTGACTTTTTGGGATTCAGTGGTTATTCTCCACACTTCGTAGCCATTTCAACCAACTCTGAGCACAAAATGCAGCCATCCTCTATGCAGCAAGCCCTGCCCAGTCAGTGACCCTACTGGACAGATCCAAGGCCAGCCCTGGTTCCCTGCTGCAGCCACCGTCCTGACGTTCATCGGAGCAGGCCGGGGCCTGGCCTTCCCGGCACAAGTGGCTGTTCTGACAGGCCCCCAGTTTGTCCCATCTGAACTGCTGGGAGGTTTCCGGGTGGCCAGAGGAGCAAAGCTGCCTTCCAAGTGCCTGTCTGTGCCTGGGAGAACAGAGCAGGAGCGTCGTGCGGTCCACCGCGCAATGCATGGCGATTCCAGGCGCTGAACAACTCCCCTGGACCCTTGGGCCTGCATCTGACTCCCAGCTGCAGAGTCAGAAGCTGAGTCCAGGCAACTGCTTGGCCACTCCCGATCGCTCCTCCCTGGACACCCGGTTACCAAAGTCAGCAAAGAAGATGCGGTAATCGCCGCCTGATCTCCACATGGTGAACACAACACTCCCACCAACACCTCCTTGACTGGTCGGTCTTCAGCACCGGGGGTGGGCAGGCAGGTGTTCTGTGTTGACGAGAATTGCACAGGCTAAACACAAACACGGAACCAGAGTGAGAACACCTCACTCACGGCAGCCCAGGCTGCTCCCTACCAGGTGACGGAGCGCGCCGGGGCTGTGGGTGCCAGGGGCTGAGTGCTAGGGACTCGTCATGAGTGGGGATCCCCACGTTCCTGTCACTGCTGTCAAACAGAAGGTAAACAGTCTTATGAATGTATTTCCTTAGGAAAACTTGTAAAAACTTTTATTAGGATATCTATTTAATACTGAACTTTGGCCTACTTTGTGATAGACTATAAACAAATTGAGGAAATCACTATTTCTCACTTCTGTATTTTCTCAAAAATAATTTTGTTACAGAGTTCAATATACTGTGTACCATTGATCTTCTATTGTGAAAGCAAAGAATTTCATCAAAATATTTTAAATTATGAGTGAAAATTGTGTATGTTAATTTTGCAGCTATAATATTAATCAAATTTCGTGTAATTCTAATCACAAAATGACGTGCCTTAAGTGCCCCTCCAGCTGTGGGTTGGCAGTGTCCAGACAGGGAGGGCCCATCACCGAAATCCTGAACGATTACTAGACCAATTCTATTAAAAACATTTCAAGGCATTTTGGGTGCAAACTTTGTTTATAAAAGAGAAATATCCACCTATGAGAATTTAA

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