Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DYNC1I2P1
Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:50264887-50267337  UCSC
Coordinates (T2T) chr10:51113071-51115521  UCSC
Coordinates (hg19) chr10:52024647-52027097  UCSC
Strand +
Parental Sequence NM_001271789.2
Parental seq. overlap 2389 bp
Parental seq. overlap (%) 56.4%
Genomic Region Intergenic
Retrocopy Summary DYNC1I2P1, located on chr10:50264887-50267337, is a retrocopy of the parental gene DYNC1I2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DYNC1I2
Full Name dynein cytoplasmic 1 intermediate chain 2
Also known as DIC74|DNCI2|IC2|NEDMIBA
Coordinate chr2:171687469-171750158
Strand +
Gene summary This gene encodes a member of the dynein intermediate chain family. The encoded protein is a non-catalytic component of the cytoplasmic dynein 1 complex, which acts as a retrograde microtubule motor to transport organelles and vesicles. A pseudogene of this gene is located on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>DYNC1I2P1
GGTTGGTGTTGGGGGCTTAGCCGAGGGACGTTACCGGAAAGTTGCAGGCGGGAGGACTCTTCCCCATCCAGTCACCTGACAGGTCACAAACATGTCAGACAAAAGTGAATTAAAGGCTGAGTTGGAACGTAAGAAGCAGCAACTGGCCCAAATCAGAGAGGAAAAGAAGAGAAAAGAAGAAGAAAGGAAAAAAAAAGAAACAGATCAGAAGAAGGAAGCTGTTGCTCCTGTGCAAGAAGAATCAGATCTTGAAAAAAGAAGAAGAGAAGCTGAAGCATTGCTCCAAAGCATGGGGCTAACTCCAGAaAATCTGTGAGCACTCCAAGTGAAGCTGGAAGCCAAGACTCTGGAGATGGCGCCGTGGGATCTAGACGAGGACCTATTAAACTTGGAATGGCTAAAATCACGCAAGTCGACTTTCCTCCTCGAGAAATTGTCACGTATACAAAGGAAACTCAGACTCCAGTTATGGCTCAACCCAAAAAAGATGAAGAGGAAGATGATGATGTAGTGGCTCCTAAACTACCTATTGAACCTGAAGAAGAGAAAACTTTAAAGAAAGATGAGGAAAATGATAGTAAAGCTCCCCCCATGAGCTGACTGAAGAAGAAAAGCAACAAATCTTGCACTCTGAGGAATTTTTAAGTTTCTTTGACCATTCTACAAGAATTGTAGAAAGAGCTCTTTCTGAGCAGATTAACATCTTCTTTCACTATAGTGGGAGAGATTTGGAAGACAAAGAAGGAGAGATTCAAGCAGGTGCTAAACTGTCATTAAATTGACAATTTTTTGACGAACGTTGGTCAAAGCATCGGGTTGTTAGTTGTTTGGATTGGTCATCTCAGTATCCGGAGTTACTCGTGGCTTCCTATAACAACAATGAAGATGCCCCTCATGAGCCTGATGGTGTGGCCCTTGTATGGAATATGAAATACAAAAAAACTACCCCAGAGTATGTGTTTCACTGCCAGTCAGCTGTGATGTCTGCCACATTTGCAAAATTTCATCCAAATCTTGTTGTTGGTGGTACATATTCAGGCCAAACTGTGCTTTGGGATAACCGTAGCAATAAAAGAACTCCAGTGCAAAGAACTCCACTGTCAGCAGCTGCACACACACACCCTGTATATTGTGTAAACGTTGTTGGAACACAAAATGCTCACAATCTGATTAGCATCTCTACTGATGGAAAAATTTGTTCATGGAGTCTGGACATGCTTTCCCATCCACAGGATAGCATGGAGTTGGTTCATAAACAGTCAAAAGCAGTAGCTGTGACATCTATGTCCTTCCCTGTTGGAGATGTCAACAACTTTGTTGTTGGGAGTGAAGAAGGTTCTGTGTACACAGCATGCCACCATGGCAGCAAAGCTGGAATCAGTGAGATGTTTGAGGGGCATCAAGGACCAATCACTGGCATCCATTGTCATGCAGCTGTTGGAGCAGTAGACTTCTCACATCTTTATGTCACTTCATCATTTGACTGGACAGTAAAGCTTTGGACAACTAAGAATAACAAGCCTTTGTATTCATTTGAAGACAATGCAGACTATGTTTATGATGTTATGTGGTCACCTACCCACCCAGCCCTGTTTGCCTGTGTGGATGGCATGGGGAGATTGGATTTGTGGAATCTCAATAATGACACAGAGGTACCAACTGCCAGCATTTCTGTGGAGGGTAATCCTGCTCTTAATCATGTGAGATGGACCCATTCTGGCAGAGAGATTGCTGTGGGTGATTCTGAAGGACAGATTGCTATATACGATGTGGGAGAGCAGATTGCTGTTCCCCGCAATGATGAATGGGCATGGTTTGGCTGAACACTTGCAGAAATTAATGCAAACCGAGCTGATGCAGAGGAGGAAGCAGCTACCCGAATACCTGCTTAGTTCCTGAAAAGGGGAGTGTAACTAGTGGATTTGGGAAAGGTTCTTAAGTAGATCCTGAGACTATTTGCATGCTTCTATCTAAATGATAATTAAAAGGAAATTTCATGGATTAAACCATGGGTTTAATGCAGCAAGGAAACTTACAATGTCCCTTTATATATAACATGCATCTTGTTTTGGATTTGTGTCATTTTTTAATATAGCTGATTGACTTCACAGAAAGCAGCTTTTTTGAATTCTAATACATAGGTGTATATTTGGTATTAGTTATTTTGAGTTCTTTTCAACTTATAACACTGTATACAGTTATTTCTAAAGCACAGATGAAATAAGTTCTGCATATTTTTAAATAATCACAGTTCCCTGTTATACAGATAATGTTCTCACTACCCATAATATGTAGGAACATTGTTTCTCCTTAGCCGTAGTATGCATACACCTATCCATGTTCATTCTGACATCCTTTGTTGTCTTTATAATTCATGTGGTAGTTACCTATAAATAAAAACAAATATGAGTTAA
>NM_001271789.2
GTGTGCTTTGGAAAGCCGCGGAGCTGGTGGTGGCTACAGTTGGTGTTGGGGGCTTAGGCGAGGGACGTTACCGGGAAGTTGCAGGCGGGAGGACTCTTCCCCATCCAGTCACCTGACAGGTCACAAACATGTCAGACAAAAGTGAATTAAAGGCTGAGTTGGAACGTAAGAAGCAGCGACTGGCCCAAATCAGAGAGGAAAAGAAGAGAAAAGAAGAAGAAAGGAAAAAAAAAGAAACAGACCAGAAGAAGGAAGCTGTTGCTCCTGTGCAAGAAGAATCAGATCTTGAAAAAAAAAGGAGAGAAGCTGAAGCATTGCTTCAAAGCATGGGGCTAACTCCAGAATCCCCCATTGTCCCTCCTCCTATGTCTCCATCCTCCAAATCTGTGAGCACTCCAAGTGAAGCTGGAAGCCAAGACTCTGGAGATGGCGCCGTGGGATCTAGACGAGGACCTATTAAACTTGGAATGGCTAAAATCACGCAAGTCGACTTTCCTCCTCGAGAAATTGTCACGTATACAAAGGAAACTCAGACTCCAGTTATGGCTCAACCCAAAGAAGATGAAGAGGAAGATGATGATGTAGTGGCTCCTAAACCACCTATTGAACCTGAAGAAGAGAAAACTTTAAAGAAAGATGAGGAAAATGATAGTAAAGCTCCCCCTCATGAGCTGACTGAAGAAGAAAAGCAACAAATCTTGCACTCTGAGGAATTTTTAAGTTTCTTTGACCATTCTACAAGAATTGTAGAAAGAGCTCTTTCTGAGCAGATTAACATCTTCTTTGACTATAGTGGGAGAGATTTGGAAGACAAAGAAGGAGAGATTCAAGCAGGTGCTAAACTGTCATTAAATCGACAATTTTTTGACGAACGTTGGTCAAAGCATCGGGTGGTTAGTTGTTTGGATTGGTCATCTCAGTATCCGGAGTTACTCGTGGCTTCCTATAACAACAATGAAGATGCCCCTCATGAGCCTGATGGTGTGGCCCTTGTATGGAATATGAAATACAAAAAAACTACCCCAGAGTATGTGTTTCACTGCCAGTCAGCTGTGATGTCTGCCACATTTGCAAAATTTCATCCAAATCTTGTTGTTGGTGGTACATATTCAGGCCAAATTGTGCTTTGGGATAACCGTAGCAATAAAAGAACTCCAGTGCAAAGAACTCCACTGTCAGCAGCTGCACACACACACCCTGTATATTGTGTAAATGTTGTTGGAACACAAAATGCTCACAATCTGATTAGCATCTCTACTGATGGAAAAATTTGTTCATGGAGTCTGGACATGCTTTCCCATCCACAGGATAGCATGGAGTTGGTTCATAAACAGTCAAAAGCAGTAGCTGTGACATCTATGTCCTTCCCTGTTGGAGATGTCAACAACTTTGTTGTTGGGAGTGAAGAAGGTTCTGTGTACACAGCATGCCGCCATGGCAGCAAAGCTGGAATCAGTGAGATGTTTGAGGGGCATCAAGGACCAATCACTGGCATCCATTGTCATGCAGCTGTTGGAGCAGTAGACTTCTCACATCTTTTTGTCACTTCATCGTTTGACTGGACAGTAAAGCTTTGGACAACTAAGAATAACAAGCCTTTGTATTCATTTGAAGATAATGCAGACTATGTTTATGATGTTATGTGGTCACCTACCCACCCAGCCCTGTTTGCCTGTGTGGATGGCATGGGGAGATTGGATTTGTGGAATCTCAATAATGACACAGAGGTACCAACTGCCAGCATTTCTGTGGAGGGTAATCCTGCTCTTAATCGTGTGAGATGGACCCATTCTGGCAGAGAGATTGCTGTGGGTGATTCTGAAGGACAGATTGTTATATACGATGTGGGAGAGCAGATTGCTGTTCCCCGCAATGATGAATGGGCACGGTTTGGCCGAACACTTGCAGAAATTAATGCAAACCGAGCTGATGCAGAGGAGGAAGCAGCTACCCGAATACCTGCTTAGTTCCTGAAAAGGGGAGTGTAACTAGTGGATTTGGGAAAGGTTCTTAAGTAGATCCTGAGACTATTTGCATGCTTCTGTCTAAATGATAATTAAAAGGAAATTTCATGGATTAAACCATGGGTTTAATGCAGCAAGGAAACTTACAATGTCCCTTTATATATAACATGCATCTTGTTTTGGATTTGTGTCATTTTTTAATATAGCTGATTGACTTCACAGAAAGCAGCTTTTTTGAATTCTAATACATAGGTGTATATTTGGTATTAGTTATTTTGAGTTCTTTTCAACTTATAACACTGTATACAGTTATTTCTAAAGCACAGATGAAATAAGTTCTGCATATTTTTAAATAATCACAGTTCCCTGTTATACAGATAATGTTCTCACTACCCATAATATGTAGGAACATTGTTTCTCCTTAGCCGTAGTATGCATACACCTATCCATGTTCATTCTGACATCCTTTGTTGTCTTTATAATTCATGTGGTAGTTACCTATAAATAAAAACAAATATGCGTTAACTTTTCAAATTTTCATTTTTACTCCTTACAACTTGAATTTTTCCATCTTTTATAAAATATATTTTTTCCATATCTTTCTTTAAGCTCCTGCTGTGAGCAGCCATCTCAAATCCTATAGAGCTGTGTACCCTAAATATACCATGTGGTATATACTATAGATCTCCCAGTGCATTATGAATTGATGTCTAGATAATCTGTTGGTGAAAAAATTTCCCCTAGGTTAACTTTTGCTTTACTACTTTATATTCTTTCCATCTAAGACATATTTCCTTTAAAGGATAAATAGAAAGCTGCCTATAATTTTCACTGATTAAGAACTATGTATGTGACCTCACTGAGAGTAAAATCTTTGAGAGAAATTGATTTCATGATTTCAGTAGCCATAAAGGCAAAGTGCTCAAATGGACCCATACTTTGGCATTAAAATCTACATCTTGAGATCTGTTGCCACAGCATTGTCTACAAGTCCGAAAGGTAGGTGACAAATATCTAAGAATCAGTATTGAAATCAGTGAATTTCAGGAATAGAGGAAAGGACTATGATCAGATCTTGATTTTATCTACTTTAAATTGTCTATTTATTTGATCCCAACCTTTTGTACTTCTGAAGTGTAACTGTCTTTTATTCAACAGAACATGAACTAGGAAGAGAGATTAGAAAACAGAATGTGAACATTTTTCTTTTAATAATTGTAACAAAGATTTGTTGGGAGAGAAATTTCCAAATAATGAGTAGTgtatagtgtaaggaataattgacctggaattattggccccaaactctgattcttgctgaagcatctatgagaagtgtgattttagccaagtctgtgccgcattctttatatgtaggaattaagttttgatttaatgatttctgaattttctttcagctctACTCAATTAAGGGGTATCAGTATGTGAAATGGAATATAGAAAAGTAGGCAATTCTTTACTTTTCTATATTCAGTTTCATAAATTAATACCCCATAATTGCCCATTATATACCAAAGACAATATCTCAAGTTATCTCATTGTAGCAGTGTCTGTGAGTCAAAACTTCAATTTTAGTAGAGTCACACTTTCTTTATATAGAAAAATTCATGTACTCACTACTCATGTAGTTACTGTATCTTTACCTTCAGTTTGTAAAAATGACTAAAAGTAGGGAAAACAAGTGTTAAAACATAATGGATAAGAAAAGGTTGGAAATCATATGGCAAATCACATGTTCCTCAGCCTCAAGGTGTGTTTAGTTGTGAAAGAAAGAATAAAATTGTTTAAATATTTCACTTTTTGGGAATGACTTCTCCCCTACTCCCCCAGAAAATGCGATGTATACCTTTGCCCATTCAACTTTAGTCCATATTTTTAGGAACACACAAATTTACTTTAAGGAATTACCTTTAAAGTTGACTATATAATAGCAAAAGAGAAAGTATTGAGACTGTCAGTGTTGATAAAGCTTCTAGCAAGATTAGGTTGACTAGAAGTGCATCACAGTTCTTTATACTTTTAGAACTAAAAGCCTTATAATTTTGAAAAATATCCAGTTACAGAAATTGTACCTTATCAGTTATACTTTTTTTCTGAGTAAGAAAACAAGCTATAGCTTTCTGGTTAATTTCTTATTTTTCGTTGTTTGGTTTTTGTCTTTTTGAGTGGAACGTTAAAGTTTATTACCTTCATGTTAAGGAATATCCAGCTTCACAGACAATTAACTTGCAATAAATCTCTGAAATAATCA

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