Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name ARL4AP3
Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:5207025-5208066  UCSC
Coordinates (T2T) chr10:5208783-5209824  UCSC
Coordinates (hg19) chr10:5248988-5250029  UCSC
Strand +
Parental Sequence NM_001195396.2
Parental seq. overlap 903 bp
Parental seq. overlap (%) 31.2%
Genomic Region Intragenic (AKR1C4)
Retrocopy Summary ARL4AP3, located on chr10:5207025-5208066, is a retrocopy of the parental gene ARL4A. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ARL4A
Full Name ADP ribosylation factor like GTPase 4A
Also known as ARL4
Coordinate chr7:12686903-12690958
Strand +
Gene summary ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ARL4AP3
Orangutan Pongo abelii ARL4AP2
Gibbon Nomascus leucogenys ARL4AP2
Green monkey Chlorocebus sabaeus ARL4AP2
Golden snub-nosed monkey Rhinopithecus roxellana ARL4AP1
Bonobo Pan paniscus Without Homology
Gorilla Gorilla gorilla Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ARL4AP3
TGTAGAAAAGCCTGCCAATGTTGCCTCATTTAGACCCAGACTCCAAAACGGGAGTCTTATAGCTGGGCCACCTAGGAAGAGAGGTTCTAAAGCATAAAAAAGAAAGCATTTCATTTTGGGACATTTATTTGCAGCTGGAAATGGGGGAATGGGCTAACTGGCTAAACTACTATCTTGTCCATCCTGCCTTCACTTCAGTCCTTCCACATTGTTATTTGGTGTTTGAACTGTGCTAGAAGAACTGTTTTATACAGGCTGCTATTCAATAAATTTGTAAATACCATACCCACACCAAAGGATTTAACACTGAAAAGATTAAGGTAATTTTGGAAAATTCTAAAAGTCACTTTTCACTCCTGAGATGTAGGTGGTCAGAAGAAATGAGGAACACTGTAGAAGCCATATGCAAGATGCACAGATGGCATTGTGTTTGTTGTGGACTGTTGATGTTAACAGGATGGAAGAAGTCAAAACTGAACTTTATAAAATAGGGTATAAGAAAATAAAGATGTCCCTGTACTTACAGGTGCTAAGAAACTAGACTTGAAGAACTTGTCTCTCTCAGAAATTGAGAAATTGTTAGCAATGGTTGAACTAAGCTCATCAACTCCTTGGCATTTGCAGCCTACCTGTGCAATCATAGGACATGAAATAAAGGAAGGACTTGAGAAACTCCATGATGTGATAATGAAGAGAAAAATATTGCAGTAATATAAAAAGATGAATATGATACCTTTTCTATATATGTAGAATAGATTTTCTCTGGTCTGATTTTGACAAATGCAAGACTGTCTACAGCCTAGTTTTCCTGTATGCCCTCCTGGGTGCTATCAAAGCTTCATTTCATTGAACAATCAGATGCCCAACTCTGTGGCTTTGTGGAAGATGAGTAAATGCAGTAATGCTTGAAATGGTCTCTTCTCCCTAGCCCACAAATATTTTGGTACTATCATTTTGGGAAGTCAAGCAAGTATAGTAAATTAACCAGAACACAATTGTGGAAATTTGATGCAAAGTTAGTGAAATAAAACTTTAAAGAGTG
>NM_001195396.2
AGAGCTGCTTGGAGAGCTAAGCTGGAAGGGTGCTTATCCCTGCGTAGAAACGCCTGCCAATGCTTTCTCATTTGGACCCAGACTCCAGATCGGGAGTCTTATAGCTGGATCAGCTACCAAGAGAAGTTGTAAACCAAGAAGAGAAAAGCATTTCAATTTGGGACATTTATTTGCACCTGGAAATGGGGAATGGGCTGTCAGACCAGACTTCTATCCTGTCCAACCTGCCTTCATTTCAGTCTTTCCACATTGTTATTCTGGGTTTGGACTGTGCTGGAAAGACAACTGTCTTATACAGGCTGCAGTTCAATGAATTTGTAAATACCGTACCTACCAAAGGATTTAACACTGAGAAAATTAAGGTAACCTTGGGAAATTCTAAAACAGTCACTTTTCACTTCTGGGATGTAGGTGGTCAGGAGAAATTAAGGCCACTGTGGAAGTCATATACCAGATGCACAGATGGCATTGTATTTGTTGTGGACTCTGTTGATGTCGAAAGGATGGAAGAAGCCAAAACTGAACTTCACAAAATAACTAGGATATCAGAAAATCAGGGAGTCCCTGTACTTATAGTTGCTAACAAACAAGATTTGAGGAACTCATTGTCACTTTCAGAAATTGAGAAATTGTTAGCAATGGGTGAACTGAGCTCATCAACTCCTTGGCATTTGCAGCCTACCTGTGCAATCATAGGAGATGGCCTAAAGGAAGGACTTGAGAAACTACATGATATGATCATTAAAAGAAGAAAAATGTTGCGGCAACAGAAAAAGAAAAGATGAATATCAATACCTATTATATCTGTGTGGAGTAGGTTTTCTCTGGTCTGATTTTGACAAATAGAAGAGTGTCTACAGCGTGGTTTGCCTGTCTGCCCTCCTGGATGCTATTAAAGCTTTGTTTTGTTGAACAATCAGATGCCCAACTCTGTTGCCTTGTGGAAGATGAGTAAATGCAGTGCTTCTTAAAGTGGTCTCTTCTCCCTACCCCACAAATCTTTTGGTACTACCATTTGGGGAAGCCAAGCAAGGATAGTAAATTGACCAGAACACAGTTGTGGGAATTTGGTCTGAAGTTAGTGAAATAAAACTTTAAAGAGTGTCTGCCTAGTGTTTTGTGCTTACATCTTTCGGGGGGAAGCCTTTGCAAGAAAATTGCATACAAGGCTTTGTAACGATCAAGTGCTAATCGATGGAAATGTTAAGGTAGATTAACATATATGCAGTTATATTGATCACATTGGTCCAACCAGTCCTTTTTTGAAGTAAGGGACAAGGAGTAAGTATTTTCTTTTTTAAGTTTCTGCCAAATGATTTTTGACGCTTTCTGGAATCAAGTAATTTAATAGTATAGCTTAATTCTAGACAATGTTTAAGTTGGTCTACCTTTATTAAAAATAAGATATTTGGGGTATATTCAAGTGCATGGATTAGTTTTCCTGACAAAGCATGTTTTGGTGTGTAGTCTTACTTTTTAGAAATAGCTATGCATCGTTCTACACAGGTTTAAAACAACTTTTTTGGGGATTTAGGGCTATTATAGGAATAGTTTGTTGTCAGAAGCACTTTCACTTGAAGAACCTAAAATGATTGACTCATTCATAGTAAATATGGGCATGTAAACTAATAAATATGCACTGGATACATATATGGATTTATGAAGAAGGCGATTTAGTCAAGAGGATGTAATTAAAATATGTGGTCTCTAAAATATTCCAGTTACAAGATATTTGTTTTATTAATATTTGCTGGCTAAAAACAAATGTGGTTTTTATATATTTTTGTAGTGTGTTGAGAAGAGCAAAAGCTTTATAAATATACCTGATGCGCTGTAGAATGAAAATGTAAAAGATAACCTGTATGTGTTCCGAGCTTTAATTTTTTGTTTACAAATTGAACAGTGTTACATGGGCTGTCCAGTCCTGATTATAGAGAGGAAGAAATGGTAACAGTATGGCAGATAAGAATTACAATTATAGAAAATGAGGGGAAAATAACAAACCTGTTTTATGAAAATTCACTGGTGCTGTTTACATTGGAATAAAAAGCTCTATAAGGAGGAAAGGCCTTTATCTAATTCTTATCTACAGACACTTACTTCCAGTGACCATATTTTACTAAATCAGCTTATTTTTTATGTCTAAAGCAACAGCTGTTCTGAAAAATCACCAAAAGAAATGCACTTTGCTAGCAGGAtttgttttggctttgggttttgtttttttgttttttttttttttCAGTGGCATAACAGTTTTTGGAACCTTGATTCTTGTGTCACACAAAATGAATGAAGTAGCTTGATGTGGAGCCTTCATATGTTAAATATTCCTGCACTAGTGATGGTCACTTAGAATGTTTATAGAAATGTGGATAATAACTACCAATAAACTACTTGAGGCACTAGGAGAACAGTATTTGACTTTGAATTTTAATGTATTTCCACTTTTGCTGAAGCTTTTAATCAGATGTGTAAAAACAATTGACCAGCTAGGCTATTTAGTCCCATAGTAGTTCAGATCTGCTTAGATGTGACAGGCATTGAAGGCTGTTTTTTTTTTTTTCTCCCTTCACTGATACTGAAATCATGGTATCTGCTGCAAACATGAGTAGATCCATGATGGATTAATAAAGCTTGCTGAAAAAAAAAATCTGTGTATCAATTAGATTTACCAGTTTGCCTGTACTTTCTGTCTACCTACTATGTAAAATAGTGCTGTTTTTAAGTATTTCAAAAGCTTGTGTGTTGACCCTTTGTAGCCTAAGTACGTAAACAAATTAATGTTATCTAAGTTTTTCATATTTCATGGACAACAAAAGAGAAAATGGTATGAACACTGTACAAACTTTGATTTATAAAAGACAATTTCAGCTATAAAACCCA

Publications

PMID - Link Title