RCPedia: Rtcs

Summary

Retrocopy Name	TRAF6P1	Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species	Homo sapiens
Coordinates (hg38)	chr10:59136193-59138246 UCSC
Coordinates (T2T)	chr10:59990152-59992205 UCSC
Coordinates (hg19)	chr10:60895953-60898006 UCSC
Strand	-
Parental Sequence	NM_004620.4
Parental seq. overlap	1952 bp
Parental seq. overlap (%)	24.7%
Genomic Region	Intergenic
Retrocopy Summary	TRAF6P1, located on chr10:59136193-59138246, is a retrocopy of the parental gene TRAF6. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	TRAF6
Full Name	TNF receptor associated factor 6
Also known as	MGC:3310\|RNF85
Coordinate	chr11:36483769-36510313
Strand	-
Gene summary	The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from, members of the TNF receptor superfamily. This protein has an amino terminal RING domain which is followed by four zinc-finger motifs, a central coiled-coil region and a highly conserved carboxyl terminal domain, known as the TRAF-C domain and mediates signaling from members of the TNF receptor superfamily as well as the Toll/IL-1 family. Signals from receptors such as CD40, TNFSF11/RANCE and IL-1 have been shown to be mediated by this protein. This protein also interacts with various protein kinases including IRAK1/IRAK, SRC and PKCzeta, which provides a link between distinct signaling pathways. This protein functions as a signal transducer in the NF-kappaB pathway that activates IkappaB kinase (IKK) in response to proinflammatory cytokines. The interaction of this protein with UBE2N/UBC13, and UBE2V1/UEV1A, which are ubiquitin conjugating enzymes catalyzing the formation of polyubiquitin chains, has been found to be required for IKK activation by this protein. This protein also interacts with the transforming growth factor (TGF) beta receptor complex and is required for Smad-independent activation of the JNK and p38 kinases. The protein encoded by this gene is a key molecule in antiviral innate and antigen-specific immune responses. [provided by RefSeq, Nov 2021]

Homology

Species	Scientific Name	Retrocopy
Chimpanzee	Pan troglodytes	TRAF6P1
Bonobo	Pan paniscus	TRAF6P1
Gorilla	Gorilla gorilla	TRAF6P1
Orangutan	Pongo abelii	TRAF6P1
Gibbon	Nomascus leucogenys	TRAF6P1
Green monkey	Chlorocebus sabaeus	TRAF6P1
Crab-eating macaque	Macaca fascicularis	TRAF6P1
Rhesus	Macaca mulatta	TRAF6P1
Golden snub-nosed monkey	Rhinopithecus roxellana	TRAF6P1
Baboon	Papio anubis	Without Homology
Marmoset	Callithrix jacchus	Without Homology
Mouse lemur	Microcebus murinus	Without Homology
Mouse	Mus musculus	Without Homology
Rat	Rattus norvegicus	Without Homology
Chinese hamster	Cricetulus griseus	Without Homology
Rabbit	Oryctolagus cuniculus	Without Homology
Pig	Sus scrofa	Without Homology
Cow	Bos taurus	Without Homology
Sheep	Ovis aries	Without Homology
Dolphin	Tursiops truncatus	Without Homology
Horse	Equus caballus	Without Homology
Dog	Canis familiaris	Without Homology
Panda	Ailuropoda melanoleuca	Without Homology
Cat	Felis catus	Without Homology
Pale spear-nosed bat	Phyllostomus discolor	Without Homology
Velvety free-tailed bat	Molossus molossus	Without Homology
Greater mouse-eared bat	Myotis myotis	Without Homology
Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
Greater horseshoe bat	Rhinolophus ferrumequinum	Without Homology
Egyptian rousette	Rousettus aegyptiacus	Without Homology
Sloth	Choloepus didactylus	Without Homology
Tasmanian Devil	Sarcophilus harrisii	Without Homology
Opossum	Monodelphis domestica	Without Homology
Platypus	Ornithorhynchus anatinus	Without Homology
Chicken	Gallus gallus	Without Homology
Turkey	Meleagris gallopavo	Without Homology
Zebra Finch	Taeniopygia guttata	Without Homology
Budgerigar	Melopsittacus undulatus	Without Homology
Painted Turtle	Chrysemys picta	Without Homology
Lizard	Anolis Carolinensis	Without Homology
Frog	Xenopus tropicalis	Without Homology
Zebrafish	Danio rerio	Without Homology
Drosophila	Drosophila melanogaster	Without Homology

Expression

Related Sequence

>TRAF6P1
CCTGCCCGCCTGGTTCGGCCGCCCGCCCCGTGCACTTGAGCGAGCAAGTGATAATCAAGTTACTATAAGTCTGCTAAACTGTGAAAACAGGTGTGGATCCAGCCAGTCTCAAAGTGACTACTGTGTGGCCATGGCCAGCTCCTGTAGCGCAGCAACAAAAAATGATAGTGTGGGCAGAACTGCCAGCACGGGGAACCTCTTCAGCTCCTTTATGGAGGAGATCCAGGGATATGATGTAGAGTTTGGCCCACCCCTGGAAAGCAAGTATGAATGCCCCATCTGCTTGATGGCATTACGAGAAGCAGTGCAAACGCCATGCAGCCATAGGTTCTGCAAAGCCTGCATCATAAAATCAATAAGGGATGCAGGTCACAAATATCCAGTTGACAATGAAATACTGCTGGAAAATTAACTATTTCCAGACAATTTTGCAAAACGTGAGATTATTTCTCTGATAGTGAAGTGTCCAAATGAAGGTTGTTTGCACAAGATGGAACTGAGACATCTTGAGGATCATCAAACACATTGTGAGTTTGCTCTTATGGATTGTCCCCAATGCCAGCCTCCCTTCCAAAAATTCCATATTAATATTTACATTATGAAGGGTTGTCCAAGGAGGCAGGTATCTTGTGACAACTGTGCTGCATCAATGGCATTTGAAGATAAAAAGATCCATGACCAGAACTGCCCTTTGGCAAATGTCATCTGTGAGTACTGCAATACTATACTCATCAGAGAACAGATGCCTAACTTTATGACCTAGACCGCCCTACAGCCCCAATTCCATGCACATTCCGTACTTTTCGTAGCCATGAAAAGATGCGGAGGAATCACTTGGCACGCCACCTACAAGAGAACACCCAATCAAACATGAGAATGTTGGCCCAGGCTGTTCATAGTTTGAGCCTTATACCCGACTCTGGGTATATCTCAGAGGTCCGGAATTTCCAGGAAAGTATTCACCAGTTAGAGGGTCGCCTTGTAAGACAATGTCATCAAATCCGGGAGCTGACTGATAAAATGGAAACTCAGAGTATGTATGTAAGTGAGCTCAAACGAACCATTCGAACCCTTGAGGACAAAGTTGCTGAAATTGAAGCACAGCAGTGCAATGGAATTTACATTTGGAAGATTGGGAATGAATTTGAAATGTTAAGAAGAGCAGAAACCTGTTGTGATTCATAGCCCTGGATTCTACACGGGTAAACACAGGTACAAACTGTGCATGCGCTTGCACCTTCCGTTACCGACTGCTCAGCGCTGTGCAAACTATATATCCCTTTTTGTCCACACAATGCAAGGAGAGTATGACAGCCACCTCCCTTGGCCCTTCCAGGATACAATATGCCTTACAATTCTTGATCAGTCTCAAGCACCTGTAAGGCAAAAACCACGAAGAGATAATGGATGCCAAACCAGAGCTGCTTGCTTTCCAGCGACCCACAATCCCACGGAACCCAAAAGGTTTTGGCTATGTAACTTTTATGCATCTGGAAGCCCTAAGACAAAGAACTTTCATTAAGGATGACACATTATTAGTGCACTGTGAGGTCTCCACCCGCTTTGACATGGATAGCCTTCAGAGGGAGGGTTTTCAGCCACAAAGTACTGATGCAGGGGTATAGCTTGCCCTCACTTGTTCAAAAACAACTACCTGGAGAAAACAGTGCCTTTCCTTGCCCTGTTCTCAATAACACGCAAACAAACAAAAATGCCACGGGAAAGATGTAGTATCTACTAGCCAGTTTTGGTTAGAGAGGTCACTTACTATTTCTTCCTCTTACAAATGATCTGAGGCAGTTTTTTCCCGGGAATCCACATGTTCCATGCTTTTTCAGAAATGTTAGGCCTGAAGTGCCTGTGGCATGTTGCAGCAGCTATTTTGTCAATTAGTATACCTCTTTGTTGTACTTCCTTGGGCTTTTGCTCTGGTGTATTTTATTGTCAGAAAGCCCAGACTCAGAGTACTAAACTTTTAATAATAATGAACTTTCCTTAAAACTTCAATCTATTTTTATAGCATTATATACAACATATTAAATGTGAAAATCACA

>NM_004620.4
AGCAGAGAAGGCGGAAGCAGTGGCGTCCGCAGCTGGGGCTTGGCCTGCGGGCGGCCAGCGAAGGTGGCGAAGGCTCCCACTGGATCCAGAGTTTGCCGTCCAAGCAGCCTCGTCTCGGCGCGCAGTGTCTGTGTCCGTCCTCTACCAGCGCCTTGGCTGAGCGGAGTCGTGCGGTTGGTGGGGGAGCCCTGCCCTCCTGGTTCGGCCTCCCCGCGCACTAGAACGAGCAAGTGATAATCAAGTTACTATGAGTCTGCTAAACTGTGAAAACAGCTGTGGATCCAGCCAGTCTGAAAGTGACTGCTGTGTGGCCATGGCCAGCTCCTGTAGCGCTGTAACAAAAGATGATAGTGTGGGTGGAACTGCCAGCACGGGGAACCTCTCCAGCTCATTTATGGAGGAGATCCAGGGATATGATGTAGAGTTTGACCCACCCCTGGAAAGCAAGTATGAATGCCCCATCTGCTTGATGGCATTACGAGAAGCAGTGCAAACGCCATGCGGCCATAGGTTCTGCAAAGCCTGCATCATAAAATCAATAAGGGATGCAGGTCACAAATGTCCAGTTGACAATGAAATACTGCTGGAAAATCAACTATTTCCAGACAATTTTGCAAAACGTGAGATTCTTTCTCTGATGGTGAAATGTCCAAATGAAGGTTGTTTGCACAAGATGGAACTGAGACATCTTGAGGATCATCAAGCACATTGTGAGTTTGCTCTTATGGATTGTCCCCAATGCCAGCGTCCCTTCCAAAAATTCCATATTAATATTCACATTCTGAAGGATTGTCCAAGGAGACAGGTTTCTTGTGACAACTGTGCTGCATCAATGGCATTTGAAGATAAAGAGATCCATGACCAGAACTGTCCTTTGGCAAATGTCATCTGTGAATACTGCAATACTATACTCATCAGAGAACAGATGCCTAATCATTATGATCTAGACTGCCCTACAGCCCCAATTCCATGCACATTCAGTACTTTTGGTTGCCATGAAAAGATGCAGAGGAATCACTTGGCACGCCACCTACAAGAGAACACCCAGTCACACATGAGAATGTTGGCCCAGGCTGTTCATAGTTTGAGCGTTATACCCGACTCTGGGTATATCTCAGAGGTCCGGAATTTCCAGGAAACTATTCACCAGTTAGAGGGTCGCCTTGTAAGACAAGACCATCAAATCCGGGAGCTGACTGCTAAAATGGAAACTCAGAGTATGTATGTAAGTGAGCTCAAACGAACCATTCGAACCCTTGAGGACAAAGTTGCTGAAATCGAAGCACAGCAGTGCAATGGAATTTATATTTGGAAGATTGGCAACTTTGGAATGCATTTGAAATGTCAAGAAGAGGAGAAACCTGTTGTGATTCATAGCCCTGGATTCTACACTGGCAAACCCGGGTACAAACTGTGCATGCGCTTGCACCTTCAGTTACCGACTGCTCAGCGCTGTGCAAACTATATATCCCTTTTTGTCCACACAATGCAAGGAGAATATGACAGCCACCTCCCTTGGCCCTTCCAGGGTACAATACGCCTTACAATTCTTGATCAGTCTGAAGCACCTGTAAGGCAAAACCACGAAGAGATAATGGATGCCAAACCAGAGCTGCTTGCTTTCCAGCGACCCACAATCCCACGGAACCCAAAAGGTTTTGGCTATGTAACTTTTATGCATCTGGAAGCCCTAAGACAAAGAACTTTCATTAAGGATGACACATTATTAGTGCGCTGTGAGGTCTCCACCCGCTTTGACATGGGTAGCCTTCGGAGGGAGGGTTTTCAGCCACGAAGTACTGATGCAGGGGTATAGCTTGCCCTCACTTGCTCAAAAACAACTACCTGGAGAAAACAGTGCCTTTCCTTGCCCTGTTCTCAATAACATGCAAACAAACAAGCCACGGGAAATATGTAATATCTACTAGTGAGTGTTGTTAGAGAGGTCACTTACTATTTCTTCCTGTTACAAATGATCTGAGGCAGTTTTTTCCTGGGAATCCACACGTTCCATGCTTTTTCAGAAATGTTAGGCCTGAAGTGCCTGTGGCATGTTGCAGCAGCTATTTTGCCAGTTAGTATACCTCTTTGTTGTACTTTCTTGGGCTTTTGCTCTGGTGTATTTTATTGTCAGAAAGTCCAGACTCAAGAGTACTAAACTTTTAATAATAATGGATTTTCCTTAAAACTTCAGTCTTTTTGTAGTATTATATGTAATATATTAAAAGTGAAAATCACTACCGCCTTGTGCTAGTGCCCTCGAGAAGAGTTATTGCTCTAGAAAGTTGAGTTCTCATTTTTTTAACCTGTTATAGATTTCAGAGGATTTGAACCATAATCCTTGGAAAACTTAAGTTCTCATTCACCCCAGTTTTTCCTCCAGGTTGTTACTAAGGATATTCAGGGATGAGTTTAAACCCTAAATATAACCTTAATTATTTAGTGTAAACATGTCTGTTGAATAATACTTGTTTAAGTGTTCCTTCTGCCTTGCTTACTTATTTCCTTGAGGTTACGAAGTAGCATCTTCCCCAGAGTTTATAATGCTGAGAACCACGTGGATACCAACTGCTCATTGTTATGCTATGTAACCCTTTTTGTCTATTCAGTGCAGAGTGAATTTCACAGCTCTGCATATGTCTTCATTTGTTTAATGCTTACAAGACAGGAGATGCACACATACAATCAGCAACATAAAAATTAAAAGTGACCCAAGTAGTCAGCGCATGTGGCATCTCATTGGTGGTGACAGAAGCTATGTGAGCCAGAAGTTTTCAGCTCTTTTGAATACCCTCTGGTTTATTTCGATTAAAAAGAACAAAATTGATTTCCTAAAATCAGAATTTTTTAAAACTTGGGAGATGATTGGAGATACCTAGGAGGTCACCAAACTAGGATTAGAAGTCACAGTGGTTGTATCACAACTTAGCTTGAGTATGTTGCTGTAGCCTAACAACTGCAGGTTCTGAGAAGGATCCTGTAGAATCCTGGAAGTAACCAGATTTTCCTAATAGGGAGATGATTTTTTTGTGTGCCATCATGTATTTGTTAAAGGCCTATATATAGATATAAAATATCGTGGAATCTAGTTCTCAGGGAGACCCGCAACTAGTATAAGCTTATAAAGGATCTAAAGATCCATCCACCATTTAAAGTTGTCTGGTAATGAGAGATGACATTGTATCCCCCAGAGAGGCCAAATCAGAGTCGCCAGCCAGCGTTCTAGATCAGCCTTAATTTCAAGAGAAAGCCAAGGACCTCATCTGCAGGGGAGTGTGGTTTTCAGCCCCAGCGAGTGTCACTTTGAACTTTCCCTTTGCTTTTTTCTCTCTTCTCCCTCCCCACCCACCCTTAGGCTCCTGATCTGGTGAGTTTGTTATGGAGTGAAAATAAAAGTCAAGCAGAGACCTTGTTTCCCGTGCCACCATTAGTACCACAAGCTCATGGCTAGTTACCACATTACTTCCTGGCAGTTTGTGTCCCTCAGCTGTGCCTTCCAACCAGCGCCTGAGAATCACTGCATACCACCCTCTAGGTAGGGAAACCTACACTGCTGCTGTTCCTGTGATTATTTTACAATGAATAAATAATTGTCAAGTTCCATTTAAAAACTGAACAGTAGTATTTTTGTATTTGCGTAGAAAAAGCCTGAAGGAAATATACTAAACTTTTTGTTGGCTTATTTTCCTTTGCGCTTGCTTATATTTTTTACATTTTCTACAATAAATGTGTACTTTTATCGGAGAAAAAAATTAAATGTTGCCACAAAACATTTAATCTCCACGCCCCCAGCTCAAAAAAGGAAATGATATTTAAAAGCTTCCTGGTCAGATTTCTATTAAAAGCACTGGCTGTGCATTAGATACAAAGAGGAGTCATTTCCTGCCTTGGTGATACTATTTTTTTCTACTAACTCAAGAGTCTTTATTAAAAAAAAAAGTTGTTTTGCCTAATTTCAGCTTTTAGCAagcttcccatctgtaaaatgatttggaccagatatttctagagtcccctccagccataacattctgtCTCAAATTAAGTTCCAACCAGCAGAACAATGACAATACTTAGGAAAGTATTTTGCCAGTATAAAATGTCTTTAACTTACTCTTTGCTGACACTGATACTTTCCTCTAATTTAGTGTCTATCAGCTGGGTCACATCTTAAGTAAAATGAGCAATTTTAACCCCCAACATTTGGCATTTTGTCATAAACCAGCCAGTTATTTTATGCTGGTCATTCATCTTGACTACAAAGTAGAATAGTCAAGCTGTCATTCCAAATAGAAAACTTTTTACTTCAATCAGAATTAAGCCTTAACCTGGAAAGTTGGTTTCTTCCTTACATTTTCCCAATCTCCTACTCTATTCTTAAACATGCTAGTTTCACTCAGTTGGGTATACAAGCCTTTGGGCTTTATGTTGTATGTTACTAACCACCTTTTACCATATTTATCTTTTGGCATCATTCTGGGACATTGCTAAATTAAAAAAGAAATTGTTTCCACTTTTTTCTGGAGATGTTCAACTAAAGGTTGttttgttttgttttttgttttgagacagtctcaccctgacgctcaggctggagtgcagtggtgcaacctcggctcactgcaacctccacctcccgggctcaagccattctcctgcctcagcctcccaagcagctgggattacaggcacccgccaccacgcccagctaatttttttgtattttgagtagagaccgggtttcaccatattggccagtctcgtctggaactcctgacctcagatgatccgcccgcctcagcctcccaaagtgctgggattacaggcatgagccaccacgcccagcGTCCAACCCACTGTTGGATGAAACTTGCTGCACGTCATACATTTTGCTGTTGGCAAACAAGTCTGAATGTTGATTTGAAGTTTGGTAGTTTATTACTATCTATTGGCAGCAAAGACTGTTTATTGGTATACTACAATATGATTTAACTTTTATTTTGGGGATAAATAGTAGAAAAAAGTGAAACAGAATGAAGGCAGGTGTTTTTTATTCTAATGATGGAATAATACAGAGATACTGGACGATCTCTAGCAGTTAATTATTGTGACCCATATAAAATTATACAGGTCACAGTATAATTCTCTATTACCGTTTTTACACCAGTAAGTCTTAGATAAACTAAGCATGCTTATGAATTATGTATACAGTTAGAATGCATTATTTTTACAGAGGAACAATTGCTTGTATGTACTAACACTGTTCTCTTGGCTTGCCTCAAGTTCTACTCATTATTTTATATAAAATACTATTAggctgggcacggtggctcacgcctataatcccagcactttgggaggtggaggctggcggattacttgaagccaggagttcgagaccagcctggccaaaatggtgaaaccccatctctataaaaatacaaaaattagccaggtgtcatgatacatgcctgtaatcccagcttcttgggaggctgaggcacgggaatcgcttgaacccgggaagcacaggttgcagtgagccaagatcatgccactgcacccccagcctgggtgacagagtgcaacactgtctcacaaaacaaaacaaaaaCATCAGATTCTGTTTGTGATGCCTAGTTGCTTACAACCTAAACAGTGCAATGCCTTAAGGAAATGAAAAGGAGCCATAAGTAGTCATTTATATTTTTATTTTGAAGTGTGCTTTTTCTAAACTCCCAGATTGACATGATGGACTGTAAGTTAGTTTCTCTGTTTCTGTCTTTGTGCCTGTAGAGTGTACTTGGCACTTACAAATTCCCAGTATCCAGAAAGATGATCTGATGAAATCAAATTGGATGGATCTTGGCAGACTGTGACACTCAATTACAGCCTTCACTTTCAGTCAAAAACGGACACTTGGCAAGGAGGTGCCTGGTTGTTTCACTAAATGTCACTTGTGTGTGTAATATTTTAAAGCTTTTTCCCCACAGGAAATTCGGGTCATAAAATCCTGAAAAATAATTCTAGGTGGGAAAAGCATTTTAGGAAATGAGAGATGTGGTGCTGCTTTTCTTCTCTCAGAGTGCTTTCTCAGCAGGACACTAGCCCTGCCTTTAAGATGGGGAAGTTGGGGCATGTGCCTCTGCTCTTACTGTCTGCAGCTCTGAAGGTAGGTGCTGTCCCACTCGGACAATCGCCCAAGCAGCAGTGACCATAGTTCTCTTCTATGCAAGTccccaggagaaggtaaactgtgtggaatggggatgtgttctggttgctgctgaatcccctcttcttaccacagtgcctggcacgttgcacacactcaaATACGTAATAATGAACATTTATTGAAAGCAGCAGTTGAAGCTGACCAATTTCTGGTACCTTGTCATGTAAATTTTAGATGGTAAGGCGCAGATGTTACTTTTTTTGCTTTTTTTCTTCAGCACTTGatgaaatttcccaaacatgcagaaatgttgaaagacttgtatagtgaacatctacgacctagaatctgcagtaatattatgttacatttgctttatcacTTGATAGATGTTACTTTTAATGAGACTTCAAGTTTGGTTTCTCTAAACAAAATATTCTAAAATAACTGAACAACTTTAATCAATTTGTCTTAAGTTCTTTGGGGGAACTTGGGACATTTGCTTTGTAACTGGAATTGCAGCCCTCACGTTAAGCTAATTTTAAACTTTGCAAATTTGTTATGCTGAATTTCAGTCTTATTTATTTTGCCTGAAGGGGTATTTTTTGTAATGGATTTATTTGAAGGTCCTTGATAAATTGTGCAGAATATTCTCGTGTTCTTTTTGCACTTGATAAATTATCTAATTTCTGTGGTGAGAATGTAATTTGGGGCCTATTTTGTTTATACAAGCTTCCAGAATTATGTTCTCAGAGGGATGAAAAGGTGTAATTTAGCATATAGGTCACTAAATTAGGAGCTAAGACACATTTTCTCCTGACTGACCATGGGTCAATCAGTTTTGTCTTCGTGTCCTTTTCCTTGTAAAGTAGAAACTAGAATTTGAAATTTAAATATTAAATAATGGGTAACATTCATTAATGTATGACTCTATTAAGAAAGACACTGTGAATCCAGGGAGGATTCTCATAATTCTGTAAACTGTATGACAAGCTGTGGAATGAAATCTGACTTTTGAAAATTGAAAGACATCCAGTGGTCTTATCACAAAGCCTGCTTTTCCTCAGAACTTAACTATTGCCATGGAATTTGTAAGCAGTTATCCTAATCCATCTGGACTCTGAAAATGCATCCTTTATGAGAGGGAGTGAATGCAAAGATAAGGGTGGGGAAACACTAATCATGAAAAGAATGAAAATCAGTGTTCAGTTTTAAGAGCAGGTTGTATTGAAGGAAGGGATTAAAGGAATTATCCAGATTTGAGGTGGCACATCTTCCACCACTCCCTGCACCATCAGCATGCACGGAGCGCATAAAACAAGCCCTGCTCCTAATGGCAGTGAAACCTCGGATGGCCTCCATCAGGTCAATACAACTGAATTGCTGGGCTGACTTAAGATTGAAGGACTCCATTTTAGTAAGTAGAGAAGTGTGACCTTTCTCAACCCAGGTTGTGAATGTGGATTCACACTTATCTCAAAAAGGCACCTGGAGTTTTAACTTTATGTCATGTCTCAGTACTGGTTGCAAGGTATGACCAAAAGTGTTCCTTGAATGGCACCTTTTTGAATATTAATTTAGAAGAAAACATGCCAGACTGACATACTTACCCCCTCCGCACTGTTACTACTTCCTTACCAGCCCTATGTACTGCATCAATGTCTACAAGAAAGCACTCTTCATTAAAATGAAATATATATATTAAAA

>NM_004620.4 

AGCAGAGAAGGCGGAAGCAGTGGCGTCCGCAGCTGGGGCTTGGCCTGCGGGCGGCCAGCGAAGGTGGCGAAGGCTCCCACTGGATCCAGAGTTTGCCGTCCAAGCAGCCTCGTCTCGGCGCGCAGTGTCTGTGTCCGTCCTCTACCAGCGCCTTGGCTGAGCGGAGTCGTGCGGTTGGTGGGGGAGCCCTGCCCTCCTGGTTCGGCCTCCCCGCGCACTAGAACGAGCAAGTGATAATCAAGTTACTATGAGTCTGCTAAACTGTGAAAACAGCTGTGGATCCAGCCAGTCTGAAAGTGACTGCTGTGTGGCCATGGCCAGCTCCTGTAGCGCTGTAACAAAAGATGATAGTGTGGGTGGAACTGCCAGCACGGGGAACCTCTCCAGCTCATTTATGGAGGAGATCCAGGGATATGATGTAGAGTTTGACCCACCCCTGGAAAGCAAGTATGAATGCCCCATCTGCTTGATGGCATTACGAGAAGCAGTGCAAACGCCATGCGGCCATAGGTTCTGCAAAGCCTGCATCATAAAATCAATAAGGGATGCAGGTCACAAATGTCCAGTTGACAATGAAATACTGCTGGAAAATCAACTATTTCCAGACAATTTTGCAAAACGTGAGATTCTTTCTCTGATGGTGAAATGTCCAAATGAAGGTTGTTTGCACAAGATGGAACTGAGACATCTTGAGGATCATCAAGCACATTGTGAGTTTGCTCTTATGGATTGTCCCCAATGCCAGCGTCCCTTCCAAAAATTCCATATTAATATTCACATTCTGAAGGATTGTCCAAGGAGACAGGTTTCTTGTGACAACTGTGCTGCATCAATGGCATTTGAAGATAAAGAGATCCATGACCAGAACTGTCCTTTGGCAAATGTCATCTGTGAATACTGCAATACTATACTCATCAGAGAACAGATGCCTAATCATTATGATCTAGACTGCCCTACAGCCCCAATTCCATGCACATTCAGTACTTTTGGTTGCCATGAAAAGATGCAGAGGAATCACTTGGCACGCCACCTACAAGAGAACACCCAGTCACACATGAGAATGTTGGCCCAGGCTGTTCATAGTTTGAGCGTTATACCCGACTCTGGGTATATCTCAGAGGTCCGGAATTTCCAGGAAACTATTCACCAGTTAGAGGGTCGCCTTGTAAGACAAGACCATCAAATCCGGGAGCTGACTGCTAAAATGGAAACTCAGAGTATGTATGTAAGTGAGCTCAAACGAACCATTCGAACCCTTGAGGACAAAGTTGCTGAAATCGAAGCACAGCAGTGCAATGGAATTTATATTTGGAAGATTGGCAACTTTGGAATGCATTTGAAATGTCAAGAAGAGGAGAAACCTGTTGTGATTCATAGCCCTGGATTCTACACTGGCAAACCCGGGTACAAACTGTGCATGCGCTTGCACCTTCAGTTACCGACTGCTCAGCGCTGTGCAAACTATATATCCCTTTTTGTCCACACAATGCAAGGAGAATATGACAGCCACCTCCCTTGGCCCTTCCAGGGTACAATACGCCTTACAATTCTTGATCAGTCTGAAGCACCTGTAAGGCAAAACCACGAAGAGATAATGGATGCCAAACCAGAGCTGCTTGCTTTCCAGCGACCCACAATCCCACGGAACCCAAAAGGTTTTGGCTATGTAACTTTTATGCATCTGGAAGCCCTAAGACAAAGAACTTTCATTAAGGATGACACATTATTAGTGCGCTGTGAGGTCTCCACCCGCTTTGACATGGGTAGCCTTCGGAGGGAGGGTTTTCAGCCACGAAGTACTGATGCAGGGGTATAGCTTGCCCTCACTTGCTCAAAAACAACTACCTGGAGAAAACAGTGCCTTTCCTTGCCCTGTTCTCAATAACATGCAAACAAACAAGCCACGGGAAATATGTAATATCTACTAGTGAGTGTTGTTAGAGAGGTCACTTACTATTTCTTCCTGTTACAAATGATCTGAGGCAGTTTTTTCCTGGGAATCCACACGTTCCATGCTTTTTCAGAAATGTTAGGCCTGAAGTGCCTGTGGCATGTTGCAGCAGCTATTTTGCCAGTTAGTATACCTCTTTGTTGTACTTTCTTGGGCTTTTGCTCTGGTGTATTTTATTGTCAGAAAGTCCAGACTCAAGAGTACTAAACTTTTAATAATAATGGATTTTCCTTAAAACTTCAGTCTTTTTGTAGTATTATATGTAATATATTAAAAGTGAAAATCACTACCGCCTTGTGCTAGTGCCCTCGAGAAGAGTTATTGCTCTAGAAAGTTGAGTTCTCATTTTTTTAACCTGTTATAGATTTCAGAGGATTTGAACCATAATCCTTGGAAAACTTAAGTTCTCATTCACCCCAGTTTTTCCTCCAGGTTGTTACTAAGGATATTCAGGGATGAGTTTAAACCCTAAATATAACCTTAATTATTTAGTGTAAACATGTCTGTTGAATAATACTTGTTTAAGTGTTCCTTCTGCCTTGCTTACTTATTTCCTTGAGGTTACGAAGTAGCATCTTCCCCAGAGTTTATAATGCTGAGAACCACGTGGATACCAACTGCTCATTGTTATGCTATGTAACCCTTTTTGTCTATTCAGTGCAGAGTGAATTTCACAGCTCTGCATATGTCTTCATTTGTTTAATGCTTACAAGACAGGAGATGCACACATACAATCAGCAACATAAAAATTAAAAGTGACCCAAGTAGTCAGCGCATGTGGCATCTCATTGGTGGTGACAGAAGCTATGTGAGCCAGAAGTTTTCAGCTCTTTTGAATACCCTCTGGTTTATTTCGATTAAAAAGAACAAAATTGATTTCCTAAAATCAGAATTTTTTAAAACTTGGGAGATGATTGGAGATACCTAGGAGGTCACCAAACTAGGATTAGAAGTCACAGTGGTTGTATCACAACTTAGCTTGAGTATGTTGCTGTAGCCTAACAACTGCAGGTTCTGAGAAGGATCCTGTAGAATCCTGGAAGTAACCAGATTTTCCTAATAGGGAGATGATTTTTTTGTGTGCCATCATGTATTTGTTAAAGGCCTATATATAGATATAAAATATCGTGGAATCTAGTTCTCAGGGAGACCCGCAACTAGTATAAGCTTATAAAGGATCTAAAGATCCATCCACCATTTAAAGTTGTCTGGTAATGAGAGATGACATTGTATCCCCCAGAGAGGCCAAATCAGAGTCGCCAGCCAGCGTTCTAGATCAGCCTTAATTTCAAGAGAAAGCCAAGGACCTCATCTGCAGGGGAGTGTGGTTTTCAGCCCCAGCGAGTGTCACTTTGAACTTTCCCTTTGCTTTTTTCTCTCTTCTCCCTCCCCACCCACCCTTAGGCTCCTGATCTGGTGAGTTTGTTATGGAGTGAAAATAAAAGTCAAGCAGAGACCTTGTTTCCCGTGCCACCATTAGTACCACAAGCTCATGGCTAGTTACCACATTACTTCCTGGCAGTTTGTGTCCCTCAGCTGTGCCTTCCAACCAGCGCCTGAGAATCACTGCATACCACCCTCTAGGTAGGGAAACCTACACTGCTGCTGTTCCTGTGATTATTTTACAATGAATAAATAATTGTCAAGTTCCATTTAAAAACTGAACAGTAGTATTTTTGTATTTGCGTAGAAAAAGCCTGAAGGAAATATACTAAACTTTTTGTTGGCTTATTTTCCTTTGCGCTTGCTTATATTTTTTACATTTTCTACAATAAATGTGTACTTTTATCGGAGAAAAAAATTAAATGTTGCCACAAAACATTTAATCTCCACGCCCCCAGCTCAAAAAAGGAAATGATATTTAAAAGCTTCCTGGTCAGATTTCTATTAAAAGCACTGGCTGTGCATTAGATACAAAGAGGAGTCATTTCCTGCCTTGGTGATACTATTTTTTTCTACTAACTCAAGAGTCTTTATTAAAAAAAAAAGTTGTTTTGCCTAATTTCAGCTTTTAGCAagcttcccatctgtaaaatgatttggaccagatatttctagagtcccctccagccataacattctgtCTCAAATTAAGTTCCAACCAGCAGAACAATGACAATACTTAGGAAAGTATTTTGCCAGTATAAAATGTCTTTAACTTACTCTTTGCTGACACTGATACTTTCCTCTAATTTAGTGTCTATCAGCTGGGTCACATCTTAAGTAAAATGAGCAATTTTAACCCCCAACATTTGGCATTTTGTCATAAACCAGCCAGTTATTTTATGCTGGTCATTCATCTTGACTACAAAGTAGAATAGTCAAGCTGTCATTCCAAATAGAAAACTTTTTACTTCAATCAGAATTAAGCCTTAACCTGGAAAGTTGGTTTCTTCCTTACATTTTCCCAATCTCCTACTCTATTCTTAAACATGCTAGTTTCACTCAGTTGGGTATACAAGCCTTTGGGCTTTATGTTGTATGTTACTAACCACCTTTTACCATATTTATCTTTTGGCATCATTCTGGGACATTGCTAAATTAAAAAAGAAATTGTTTCCACTTTTTTCTGGAGATGTTCAACTAAAGGTTGttttgttttgttttttgttttgagacagtctcaccctgacgctcaggctggagtgcagtggtgcaacctcggctcactgcaacctccacctcccgggctcaagccattctcctgcctcagcctcccaagcagctgggattacaggcacccgccaccacgcccagctaatttttttgtattttgagtagagaccgggtttcaccatattggccagtctcgtctggaactcctgacctcagatgatccgcccgcctcagcctcccaaagtgctgggattacaggcatgagccaccacgcccagcGTCCAACCCACTGTTGGATGAAACTTGCTGCACGTCATACATTTTGCTGTTGGCAAACAAGTCTGAATGTTGATTTGAAGTTTGGTAGTTTATTACTATCTATTGGCAGCAAAGACTGTTTATTGGTATACTACAATATGATTTAACTTTTATTTTGGGGATAAATAGTAGAAAAAAGTGAAACAGAATGAAGGCAGGTGTTTTTTATTCTAATGATGGAATAATACAGAGATACTGGACGATCTCTAGCAGTTAATTATTGTGACCCATATAAAATTATACAGGTCACAGTATAATTCTCTATTACCGTTTTTACACCAGTAAGTCTTAGATAAACTAAGCATGCTTATGAATTATGTATACAGTTAGAATGCATTATTTTTACAGAGGAACAATTGCTTGTATGTACTAACACTGTTCTCTTGGCTTGCCTCAAGTTCTACTCATTATTTTATATAAAATACTATTAggctgggcacggtggctcacgcctataatcccagcactttgggaggtggaggctggcggattacttgaagccaggagttcgagaccagcctggccaaaatggtgaaaccccatctctataaaaatacaaaaattagccaggtgtcatgatacatgcctgtaatcccagcttcttgggaggctgaggcacgggaatcgcttgaacccgggaagcacaggttgcagtgagccaagatcatgccactgcacccccagcctgggtgacagagtgcaacactgtctcacaaaacaaaacaaaaaCATCAGATTCTGTTTGTGATGCCTAGTTGCTTACAACCTAAACAGTGCAATGCCTTAAGGAAATGAAAAGGAGCCATAAGTAGTCATTTATATTTTTATTTTGAAGTGTGCTTTTTCTAAACTCCCAGATTGACATGATGGACTGTAAGTTAGTTTCTCTGTTTCTGTCTTTGTGCCTGTAGAGTGTACTTGGCACTTACAAATTCCCAGTATCCAGAAAGATGATCTGATGAAATCAAATTGGATGGATCTTGGCAGACTGTGACACTCAATTACAGCCTTCACTTTCAGTCAAAAACGGACACTTGGCAAGGAGGTGCCTGGTTGTTTCACTAAATGTCACTTGTGTGTGTAATATTTTAAAGCTTTTTCCCCACAGGAAATTCGGGTCATAAAATCCTGAAAAATAATTCTAGGTGGGAAAAGCATTTTAGGAAATGAGAGATGTGGTGCTGCTTTTCTTCTCTCAGAGTGCTTTCTCAGCAGGACACTAGCCCTGCCTTTAAGATGGGGAAGTTGGGGCATGTGCCTCTGCTCTTACTGTCTGCAGCTCTGAAGGTAGGTGCTGTCCCACTCGGACAATCGCCCAAGCAGCAGTGACCATAGTTCTCTTCTATGCAAGTccccaggagaaggtaaactgtgtggaatggggatgtgttctggttgctgctgaatcccctcttcttaccacagtgcctggcacgttgcacacactcaaATACGTAATAATGAACATTTATTGAAAGCAGCAGTTGAAGCTGACCAATTTCTGGTACCTTGTCATGTAAATTTTAGATGGTAAGGCGCAGATGTTACTTTTTTTGCTTTTTTTCTTCAGCACTTGatgaaatttcccaaacatgcagaaatgttgaaagacttgtatagtgaacatctacgacctagaatctgcagtaatattatgttacatttgctttatcacTTGATAGATGTTACTTTTAATGAGACTTCAAGTTTGGTTTCTCTAAACAAAATATTCTAAAATAACTGAACAACTTTAATCAATTTGTCTTAAGTTCTTTGGGGGAACTTGGGACATTTGCTTTGTAACTGGAATTGCAGCCCTCACGTTAAGCTAATTTTAAACTTTGCAAATTTGTTATGCTGAATTTCAGTCTTATTTATTTTGCCTGAAGGGGTATTTTTTGTAATGGATTTATTTGAAGGTCCTTGATAAATTGTGCAGAATATTCTCGTGTTCTTTTTGCACTTGATAAATTATCTAATTTCTGTGGTGAGAATGTAATTTGGGGCCTATTTTGTTTATACAAGCTTCCAGAATTATGTTCTCAGAGGGATGAAAAGGTGTAATTTAGCATATAGGTCACTAAATTAGGAGCTAAGACACATTTTCTCCTGACTGACCATGGGTCAATCAGTTTTGTCTTCGTGTCCTTTTCCTTGTAAAGTAGAAACTAGAATTTGAAATTTAAATATTAAATAATGGGTAACATTCATTAATGTATGACTCTATTAAGAAAGACACTGTGAATCCAGGGAGGATTCTCATAATTCTGTAAACTGTATGACAAGCTGTGGAATGAAATCTGACTTTTGAAAATTGAAAGACATCCAGTGGTCTTATCACAAAGCCTGCTTTTCCTCAGAACTTAACTATTGCCATGGAATTTGTAAGCAGTTATCCTAATCCATCTGGACTCTGAAAATGCATCCTTTATGAGAGGGAGTGAATGCAAAGATAAGGGTGGGGAAACACTAATCATGAAAAGAATGAAAATCAGTGTTCAGTTTTAAGAGCAGGTTGTATTGAAGGAAGGGATTAAAGGAATTATCCAGATTTGAGGTGGCACATCTTCCACCACTCCCTGCACCATCAGCATGCACGGAGCGCATAAAACAAGCCCTGCTCCTAATGGCAGTGAAACCTCGGATGGCCTCCATCAGGTCAATACAACTGAATTGCTGGGCTGACTTAAGATTGAAGGACTCCATTTTAGTAAGTAGAGAAGTGTGACCTTTCTCAACCCAGGTTGTGAATGTGGATTCACACTTATCTCAAAAAGGCACCTGGAGTTTTAACTTTATGTCATGTCTCAGTACTGGTTGCAAGGTATGACCAAAAGTGTTCCTTGAATGGCACCTTTTTGAATATTAATTTAGAAGAAAACATGCCAGACTGACATACTTACCCCCTCCGCACTGTTACTACTTCCTTACCAGCCCTATGTACTGCATCAATGTCTACAAGAAAGCACTCTTCATTAAAATGAAATATATATATTAAAA

Publications

PMID - Link	Title