Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name LRRC40P1
Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:63358821-63359092  UCSC
Coordinates (T2T) chr10:64216961-64217232  UCSC
Coordinates (hg19) chr10:65118581-65118852  UCSC
Strand +
Parental Sequence NM_017768.5
Parental seq. overlap 227 bp
Parental seq. overlap (%) 8%
Genomic Region Intragenic (JMJD1C)
Retrocopy Summary LRRC40P1, located on chr10:63358821-63359092, is a retrocopy of the parental gene LRRC40. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name LRRC40
Full Name leucine rich repeat containing 40
Also known as dJ677H15.1
Coordinate chr1:70144805-70205676
Strand -
Gene summary Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in signal transduction. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes LRRC40P1
Bonobo Pan paniscus LRRC40P1
Gorilla Gorilla gorilla LRRC40P1
Orangutan Pongo abelii LRRC40P1
Green monkey Chlorocebus sabaeus LRRC40P1
Crab-eating macaque Macaca fascicularis LRRC40P1
Rhesus Macaca mulatta LRRC40P1
Baboon Papio anubis LOC101021668P1
Golden snub-nosed monkey Rhinopithecus roxellana LRRC40P1
Marmoset Callithrix jacchus LRRC40P1
Gibbon Nomascus leucogenys Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>LRRC40P1
CAAAATACTACCTTAAGTTCTACAACATACATTCACATTTAAAACAGTTTTGATTAGTAACGATCAGATTGTATCTTGTGGACCCTCCGAAAATGAAGATGACAGAAAATCTAACCATGTTGGACCTTCAAAATAATGACCTCCTTCAATTTCCACCGAAGCATGGTAATTGTGTGAATTTAAGAATATTACTACCAGATAGAAATCCATTTCATATTCTTTGAGCAGCCATACTAATGAAAGGAACACCTGTTATACTAGAATATTTGAGA
>NM_017768.5
ACGGGTGGGGCTGCAGCTTCTGGACCTAGGACTTTGAACATGTCGCGCCTGAAGCGGATAGCGGGGCAGGATCTCCGCGCTGGTTTCAAAGCAGGTGGAAGAGACTGCGGTACCTCGGTACCCCAAGGGCTGTTGAAGGCAGCGAGGAAGAGCGGCCAGTTAAACCTGTCGGGTAGAAACCTCAGTGAAGTGCCGCAGTGTGTCTGGAGAATAAATGTGGATATCCCTGAGGAAGCTAATCAGAATCTTTCGTTTGGTGCTACTGAAAGATGGTGGGAGCAGACAGATTTGACCAAACTAATAATATCAAACAATAAACTTCAGTCACTTACAGATGACCTGCGACTCTTGCCTGCACTGACTGTTCTTGATATACATGATAATCAGTTGACATCCCTTCCTTCTGCTATAAGAGAGCTAGAAAATCTTCAGAAACTTAATGTCAGCCATAATAAACTGAAAATACTCCCTGAAGAAATTACAAACCTAAGAAACCTGAAGTGCCTGTATCTCCAGCATAATGAATTAACCTGCATATCAGAGGGATTTGAACAACTTTCCAATTTAGAAGATTTAGATCTTTCAAACAATCATCTTACAACTGTTCCTGCTAGTTTTTCTTCTCTGTCCAGTCTGGTGCGACTCAATCTTTCTAGTAATGAACTGAAGAGTTTGCCAGCAGAAATAAATAGAATGAAAAGGTTGAAGCATTTGGATTGTAATTCAAATCTCTTGGAAACTATACCTCCTGAATTGGCTGGCATGGAATCACTAGAATTGCTTTATTTGCGGAGGAATAAATTACGTTTTCTACCAGAATTTCCTTCTTGTAGTCTATTGAAGGAATTGCACGTAGGTGAAAACCAGATTGAAATGTTAGAGGCAGAACATCTTAAACATCTGAATTCAATTCTTGTGCTAGACCTGAGGGATAACAAGTTAAAATCTGTTCCAGATGAAATTATACTACTACGGTCCTTGGAAAGGCTTGACCTAAGCAACAATGATATTAGTAGTCTTCCCTATTCATTGGGGAACCTTCATTTGAAATTTTTGGCATTAGAAGGAAATCCTTTGAGAACAATTCGAAGAGAAATTATAAGTAAAGGAACACAAGAAGTCCTAAAATATCTACGAAGCAAGATCAAAGATGATGGACCTAGCCAAAGTGAGTCTGCTACTGAGACTGCCATGACACTACCAAGTGAATCCAGAGTCAATATACATGCCATCATTACATTAAAAATATTAGACTATAGTGATAAACAAGCAACTTTGATTCCTGATGAGGTGTTTGATGCAGTAAAAAGCAACATCGTCACTTCTATTAACTTCAGTAAGAATCAACTATGTGAAATTCCAAAAAGGATGGTAGAACTGAAGGAAATGGTTTCTGATGTCGATCTCAGTTTTAATAAACTTTCCTTTATATCCTTGGAGTTATGTGTGCTTCAGAAATTGACTTTTTTAGATCTCAGGAACAATTTTTTAAATTCTTTGCCAGAAGAAATGGAATCACTGGTAAGACTGCAAACGATCAATCTTTCCTTTAATAGGTTTAAAATGCTACCTGAAGTTCTATATCGTATCTTCACACTTGAAACAATTCTGATTAGTAATAATCAGGTTGGATCTGTGGACCCTCAGAAAATGAAGATGATGGAAAATCTGACCACGTTGGACCTTCAAAATAATGACCTCTTACAAATTCCACCAGAGCTCGGTAATTGTGTAAACTTAAGAACATTACTACTGGATGGAAATCCATTCCGAGTTCCTCGAGCAGCCATATTAATGAAAGGAACAGCTGCTATACTTGAATATTTGAGAGACCGAATTCCTACTTAACATGGAGTTGCTTTATAACCCTTGTCATGTATTATTAACCCTGGTTAATTCTAAGGAGGATGTAACATTTGTTTTAGTATCATCTTAAAAGGTGATTATTGTAATTGATCTTGTAGTTTCCCAGTATCACCTACCTGTTGGTATAATTAGCCTGGGCCATATTCACTGCCAGTAAATATTTTTACATTTTTATTTAAGATTTTTGTAAGGTGTTGTATACATTTGTAATGGTGATAACCACAATGTGTTCATACATTTGTTCTAAATGTTTTGCTTATGATTTATCCTGCTAACTTTCATTTTCTTATAGCAAGCAGTTTTTTCAAAAATGAATTTTTATTTAATGTGGTTCAGTATTATAATAACAAAGCATTTTTGTAGAACTGGTTTTTTTTCTCATTTATTTTTGTATTCCATACAATGTGACCAATTGACTTGAATATGACTAGCCAGTTTCTATGTTTTTGTTAGATATAAAATTAAATCGAATTTTGTTGAATACTGTTCTTTGGCATTTAAAAAATAAGACCTTCTTATCTTGGGCCACATGTCAAAAGAAAAAGGAAACAAAAATATATTAAAAATAAGACTTTTCATTACCCATGATAGGACTTTTGTGATATGGCTAATCTCAGTACACATTTCAACTTAAAACCTTTTTATTTACAGCACCATAATTTTAAAATTTACTTGCAATCTTGGTAAGACTAAACTTGCAGTGTTTTTCTAAAAGGGAATTTGATAGGTAAACTTGATTTAATAAAAATTAAATATCATTTTTGTTTACACCAAAATTATCAGAAGTAGGTTGATTAGTCATTATAACACTTACCATATGATTCTATTAAGAAGTCAATTCAGTAGCATGTATATCAATTTATATAGATAGGTAGATAGCTTTTGGATGATTGAGGCATGCTTATATTATGAAAAAAATTGCTAATAAAGATAAATACTACATGTTCAGAATAAAAGTTACATTTTTCAAATATTGA

Publications

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