Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name FARSBP1
Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:80776051-80778068  UCSC
Coordinates (T2T) chr10:81649800-81651816  UCSC
Coordinates (hg19) chr10:82535807-82537824  UCSC
Strand -
Parental Sequence NM_005687.5
Parental seq. overlap 798 bp
Parental seq. overlap (%) 10.4%
Genomic Region Intergenic
Retrocopy Summary FARSBP1, located on chr10:80776051-80778068, is a retrocopy of the parental gene FARSB. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name FARSB
Full Name phenylalanyl-tRNA synthetase subunit beta
Also known as FARSLB|FRSB|HSPC173|NEDBLLA|PheHB|PheRS|RILDBC|RILDBC1
Coordinate chr2:222566899-222656092
Strand -
Gene summary This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes FARSBP1
Bonobo Pan paniscus FARSBP1
Gorilla Gorilla gorilla FARSBP1
Gibbon Nomascus leucogenys FARSBP1
Green monkey Chlorocebus sabaeus FARSBP1
Crab-eating macaque Macaca fascicularis FARSBP1
Rhesus Macaca mulatta FARSBP1
Baboon Papio anubis FARSBP1
Golden snub-nosed monkey Rhinopithecus roxellana FARSBP1
Marmoset Callithrix jacchus FARSBP1
Orangutan Pongo abelii Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>FARSBP1
GTTTAAGGTCATCCATATGCATCTGGACGGAATTACACAGCTGTGCAATGTACCTCCTGTTGAAAATAAAGGGGGATATGTGATCAAATCATCAAAAGGAACCGCTTTCTTCCCTGGGCAATGCACAGAGATCTTTGCCAGGAGTCAAAATGTCAGGAAGCTTGGAGTCCTTCATCCTGATGTTATCACCAAATTTGAGCTGACCATTCCCTGTTCCTCCCTGGAAATCAATATTGAGCCCTTTTTGTGAAGATAGGTCCTTGTTGTGTGATTCTCTTCCCAAGTATCCCTTTCTCCTCCCCTGATGTCCTTTAGTCCTACTCCACAGAAAACATTCATGTGTGCTTTCATGTTTAGTAAAGTCTCAGAGAAACTCCAGAAAATCTTGCCTAGCTTCTGACCAGGATGTATTTGAAGTCCAAAGTCATCGGCAATGGGAATCACACTGAGAATAAAATCCCTCTGACCACAGCTGACATTATCCATGCATGTGATATTGTAGAAGATGCAGCTATTGCTTATGGATATAACAATATTCAGATGACTCTCCCATAAACACCACAGCTAATCAATTTCCTCTTAATAAGCTCAAAAAATTTATCAGACATGACATGGTAGCTGAATCCATGGTAGACATGGATTCACTGAAGCACTCATCTTTGCTCTCTGCTCCAAGAGGATATTTCTGATAAACTTGTTTTGGATTATCTCTGCAACAAAAGCAGTCCACATAAGTAAAACTAAAACAGCTCAATTACGCGCAGCATTCATTACCCTTCTTGGTGCTCTGAAGACCATAGAAACAAATCAGAAGATGCTCCTTCCTCTAAAACTATTTGAAATCTCTAACATTGTAATAAAAGATTCTAGCAGAGATGTAGGTACAAAATATTTTTAATTAAAAATTGTTCAAAAAGATATAGTGAAAGCTGATTTCGTTTCTGTTCTTCCAAACCCTGGGCCAGGCCTACACTGATGAAGAATTTGATGAACTATGTTTTCAATTTGGTCTGGAAGTTGATGACATTACTTTTGAGAAGGAAATAAGTAATGAACAAGATAATGTAAAGGCAGAAGGGACTTCTAATGTTCTTTGCAAAATTGACATCTCTGTCAATAGATATGACTTCATGTATCTGGAAGGATTGATTTGAGGACTTCAGGTCTTCAAAGAAAGGATAAAGGCTCTGGCATATAAACAGGTAATGCCTAATGGAAAAATCCAGAAATTGATTATCACAGAAAAGATAGTTAAGGTATGCCCTTTACAGTAGCAGCAGTTCTCCAAAATCTAAAGCTTACTAAAGATCAATATGACAGCTTCATTGAACATCAGGAGAAATTGCATCAGGATATTTGCTGGAAAAGAGCATTGGTTGCTACTGGAACCCATTGGACACTTTGTCACCCATTTACTTGTACTGTGCAAAGTGTCCTTTAGATATCAAGTGCAAGCCCTAAATAAGGCCAAGGAGTATACAGTCTGTGAGCCGATGAACATGTACAAGACTGACAACCACCTTAAACACTATTAACATGTCATTGGAAATAAACCCCTGTACCCAGTTATCTATGATAGCAAGGGTGTCGTCCTTTCAATGCCTTCCATCACCAATGAGGATGACTCCAAAATTAAATACTAGAAAGGTATTTATCAAATGCACAGGAAGTGACTTTACTAAGGCAAAAAGAGTTCTTGATATTATCTTGACACCATTTTCAGTGACTATATTGAGAACCAATTTACAATCGAAGCAACTGAGGTAATTTTCCTAATGGAAAAGCATATACTTTTCCAAAACTAGCTTACCAAAAGGAGATAGTGAg
>NM_005687.5
GCAGTGAGTTCGACACACCATGCCGACTGTCAGCGTGAAGCGTGATCTGCTCTTCCAAGCCCTGGGCCGCACCTACACTGACGAAGAATTTGATGAACTATGTTTTGAATTTGGTCTGGAGCTTGATGAAATTACATCTGAGAAGGAAATAATAAGTAAAGAACAAGGTAATGTAAAGGCAGCAGGAGCCTCTGATGTTGTTCTTTACAAAATTGACGTCCCTGCCAATAGATATGATCTCCTGTGTCTGGAAGGATTGGTTCGAGGACTTCAGGTCTTCAAAGAAAGGATAAAGGCTCCAGTGTATAAACGGGTAATGCCTGATGGAAAAATCCAGAAATTGATTATCACAGAAGAGACAGCTAAGATACGTCCTTTTGCGGTAGCAGCAGTTCTCCGTAATATAAAGTTTACTAAAGATCGATATGACAGCTTCATTGAACTTCAGGAGAAATTACATCAGAATATTTGCAGGAAAAGAGCACTGGTTGCCATTGGTACCCATGATTTGGACACTTTGTCGGGCCCATTTACTTATACTGCAAAGCGTCCTTCAGATATCAAATTCAAGCCTCTAAATAAGACCAAGGAGTATACAGCCTGTGAACTGATGAACATATACAAGACTGACAATCACCTGAAACATTATTTACATATCATTGAAAACAAACCCCTGTATCCAGTTATCTATGATAGCAATGGTGTCGTCCTTTCAATGCCTCCCATCATCAATGGGGATCATTCCAGAATAACAGTAAATACTAGAAATATTTTTATTGAATGCACGGGAACTGACTTTACTAAGGCAAAAATAGTTCTTGATATTATTGTCACCATGTTCAGTGAATATTGTGAGAATCAATTTACGGTCGAAGCTGCTGAAGTGGTTTTTCCTAATGGAAAATCACATACCTTTCCAGAATTAGCTTACCGAAAGGAGATGGTGAGAGCTGACCTAATTAACAAAAAAGTTGGAATCAGAGAAACTCCAGAAAATCTTGCCAAACTTCTGACCAGGATGTATTTAAAATCAGAAGTCATAGGTGATGGGAATCAGATTGAGATTGAAATCCCTCCAACCAGAGCTGACATTATCCATGCATGTGATATTGTAGAAGATGCAGCTATTGCTTATGGATATAACAACATTCAGATGACTCTCCCGAAAACTTACACCATAGCTAATCAATTTCCTCTTAATAAGCTCACTGAACTTCTCCGACATGACATGGCAGCCGCTGGCTTCACTGAAGCACTTACCTTTGCCCTGTGCTCCCAAGAAGATATTGCTGATAAACTAGGTGTGGATATCTCTGCAACAAAGGCAGTCCACATAAGTAATCCTAAAACAGCTGAATTTCAGGTGGCACGCACTACCCTTCTTCCTGGCCTCCTGAAGACCATAGCAGCAAATCGTAAGATGCCCCTTCCACTGAAACTGTTTGAAATCTCTGACATTGTAATAAAAGATTCTAATACAGATGTAGGTGCAAAAAACTACAgacatctctgtgctgtttattacaacaagaatcctgggtttgagatcattcatgggctgctggacagaattatGCAGTTGCTCGATGTGCCTCCTGGTGAAGACAAGGGGGGATATGTGATCAAAGCATCAGAAGGGCCTGCTTTCTTCCCCGGGCGATGTGCAGAGATCTTTGCCAGGGGTCAAAGCGTCGGGAAGCTTGGGGTCCTTCATCCTGACGTTATCACCAAATTTGAGCTGACCATGCCCTGCTCCTCCCTAGAAATCAATGTTGGACCCTTTTTGTGAAGATTGGTCTCTGTGGTGTGATTCTCTTCCCAGGTGTCCCTTTCTCCTCCCCTAGTGTCCTTAAGTCCTCCTCCACAGGGAACATCTATTTGGGCTTTGATGTTTAATAAAGTAGAAAGCACTGTCTGGCTGTGTGGGTAGAGACCATCCTTTCCCTGCATATTAGGCCAGCTTGTGCCATATACCAGTGTGGTGTCTGTGTGTGAAGCTGCATTGTTGGGTAAAAGCCCCGTGGAGTGCTGGAGAAATGCACTAGCAGAGTGCAGGATCTGTTCTGAAAGGCAGACGTGCTCCTCAGACATCAGAACATCACATTGGAACGGATTACTCCTGCATAACAAGATCCCATTTCTTTCCTTATTGATAAAACAAGATAATCGATGAGAATTCATGTTGCATGAGTTCGAGATAACTGAGGGGTTTAGCTTTGATTTTCTACATTTGACATGTATTCATCATTGAGAAACACTAAAATAACAATATTTTTAGAAAACGTTTAAGAATCAATTATGGTCCAACAATTATAGCTTCTGAGGTCAGTTTAAAGTGAAAGAAAAATCTGTAATACAAGGATTCAAAATATGTGAGGGTGCATAGGTATTTTTTACTCTATCTGTGATACTCTAAGATAGAGTACATGCAACAAAGATCTGTTCTGCTGTAAGAGTTAAAATGGACAAGTATTGATATCAATGCAGTATGAACATTAGGAAACAATGAGAAGCTTATTTTTGCCATAGGCCATACATGTTACTGTAATCAGTCAGTTATAAAATCATGGTTTTAAATACTTAATTGAGCTACTAGTTTCTCTATTGTCCCAGGGAGATATTAGACCTCTCTTTTTCTGAAGCTAAGCTTCAGCCAATCCTCCTTGTTTTATATCCTAATTTCCTTTCTTACTTCAATCTAGAATTCTCCAGTAGGTACCATCTCTGGAAAAAAGCTGGGTCTCATGTTTGAGACAAGTTCCCAGGTACTATTGAAGTAATAAGAAATATGATAAAATATAATACTTTAAAGTCCCAGTAGAAATAGCTAACAAAggctgggtgcgctgtggctcatgcctgtaatcctagcactttgggaggctgaggtgggcagatcacttgaggccaatagttcgagatcagcctgaccaacatggtgaaatgccatctccactaaaaatataaaaattagccaggcatggtggtgtgggcctgcagtcccagctacctgggaggctgagtcaggaaaatctcttgaaccaggaggtggacgttgcagtgatcccagattgtgccactgccctccagcctgggtgacagagtgagattctgtctacaaaaaaaaaaaagaagaaGTAGCTAACAAAGATAGTGAAATAAGAATTATGTTTATGGATCTTTTGCTGAGTCTACTACTAGGAGAAAACCTGACCATATTACAACCTTGAATTGGGGCAGCAGTGTCTAACTCTGTAAGATTTGTGAACACACACACTTCCAGCTGACCCTTCACAGCTCTGTTATAAGCAGATCCTTACAACATTTTAAAAATGAAATATGCCCTCTAAaaataatgcatgccaaaaggacttgtatccagcatgcataaagatttcttaaaacttaataataaaacttaatagtaaaaataaaacaactgttttttaaaaatgtgcaagagttgagcaaacatttcccaaaagatgacatatgaatgagcacttgaaaagatcctcaacatcgttagtcatcagggaaatgcaactaaaattcacaatgacaaactgcatacccattaaaatggctaaaatttaagattcataaatcaaatactgctgagactggagcaagtggaactttcatgcactgctggtgagtcacaatgtaaaatgttacattgtgactttagaaaacagcttggcagtctcttgaaacatacacctaccatctagccattctattcctaggtttacccatatggccaaagatttttatgcaagtgttcacagtgttacttatagtagttacaaattgcagtatatccatactatgaaatacttctcagcaataagaaggaatgaactactgatcctcaaaacaacatgaatgaatttcaaaacagtatgctaagtgaaagcaagagacacaaaagactctatttaattctatttacctgagagtctaaaaaagtcaaaagcaggtggtcggcaggacctcaggaaagagaactgactgcagtgggttaagagaaaactttttggggtgatggaaattttatcttaattgaggtggtaggtgtacttcaggtgtaggttatacctttgtaaagctGGGAGAAAAAGAATGTAATGTAACATGTAGTATTTTACTGATTTTAACTACATAACACCAGTTGATAAATGCCTAGAGAAATAGCCTGAACTGTAGAATTGGCAGTTGTGCTCAAGGTGGCTCACTGGTCCACAGCTATTAATGATATATTCTCCCTTAGTTTCAGGTTCGCTCTAGTTAAAATCATGGCTTATGGATCATCATATGATAGCCCTTGTTGAAGTAGGTGGAACCATTTGTTCTGTCAGCAGCTACCCACCTGGATATTTTTGGGGGTGGCCAAAATTACTTGTAATGAAAAACCCACTAATGCCTAATTGTATATCCCAGCATGAAAGGGGAAAGATCAACTCCATGCATCATGTAGATGTTTCTGCCCTCGGAAGCAGGAAATGGTAGGCAGAAAAACAGTGTCGGCTGCATTGGAAGAAGCGAATCCAGCTCATGAGTCGAGGCTCTGCAGCCAGATCATCTTACACTTGTCCCTGGTGAAGCATTTGAACTGGAGCCAGGGCAGTCTGTGAGTACTGCCAAAAGCCTTTATTACAGAAGATGCACACCTTCTTAGTAAAAACTGGGAGCTCTAGTATTAAAGTGAAAATTAAATGGAATTGATTTTTGTTCTAGCTTAGAAAAAACTTAAATTCTACCACTACAGCCTCACAGTCCTGCAGTGCTCTTCTAGttttgtttgttttttgtttttttagacggagtctcgctctgtcacccaggctggagtgcaatggcacaatcttggctcactgcaacctccacctcctgggttcaagcaattctcctgcctcagcttcccgagtagctgggactacaggtgtgtgccaccatgcctggataatttttgtatttttagtagagacggggtttcaccacgttagctaggctggtctcgaacttctgacctcaggcgatctgtccacctctgcctcccaaagtgctgggattacaggcgCCCAGCCTGCTCTTCTGTTTTTAAATTATTTTTGAATTGATCTTttttcacattttaatttttttggtttaataacggtatgagagtaggaattctccctgatgtgtagggtgaaaacagttgagtttcagagagatcaataacttactcagaagtcacatagccaataaatgAGTTTGAGACACTATAAAAGAGTGACTTGGAGTCCACAGACCACTCACTGATTTGCATTATTTACTTATTTATGCGAAAGTAAATAATGGGACTTTCTACACTTTTTAAAAATATAAAAATAATGGGAGACAAAAAGTTAAAAATTGTTAAGTCCAATACTTTAAAAAAACTCTGCAAACTGTGGCCTTACTGAGTTAATCTACCTTTCTTCCTCCTGATTCCCTGAAGTAACTAACTGCTGTTAACAATTTAGCCTGTATTGTTCCTTAGTTTGGACATTTTCCTTGATTTGTACAGTCAGCCACACACACCTGCTCACATTTTTGGGGGTCATGCTCTACTTACTGGTTTGCAACAAGTTTTGTTTTTTATTTTACATATATCTCATGACAtttcacttaatatgccccattttttcaggtcagtgcctatagacctatctcattcttttaaatgaggtaatattctattgtacagatgtccgtaattgttcaattattcccttgttggtggacattcagttgtttccaactgtttgcaattataaacactgctccaatgaaccccctATCCTGCTAAATAGCACTGGCTTAGGACCCCAAGGAAAACCAGTCCTAATGGGTGCAAGACTGTATAAATATCCACATTTGACAGACACATTCAGAGATGCATAGAGTTCATTAGATATTTCTTTGATGTGACGTTTGTACTTGAACTATATATTATTCCAGTACCTTACATCTTAGATGTAGAAGTCGCTAGGTCAAAGGATGTGTTTTGAATTTAAAACATGTTGAATGACTGTTCTCACATTTTAAACAGGAGTAATCTACTACAAACCAGCCAGCCTAACCACTGCCCCTGCTCTCAGCAATGATGGGCTCATCAGCTTGGTAAGAGAGAACATTACTCACAATCTTGCTTCTCAATCTTAATCTATTTGTGCTTGGTGTTTTATATAACATCACTAACCCTAATACTTGAGTATTTACTTTGGCCCTTCTGTCCATTTTATCCAAAAGCAAACAGATAGCCTTCAAGGGACACCATTGCCTTAAGCAGAATATGCCTCCTAAGCATTGAAAGCCTTTGACCCATCTGATATCCAAGTTCTGGCTTATTATGTTATTAGGGCCTTGAATAACTTTATGTATATTATtatggactgaatgtatccccacaaattcatgttgaccctctgacctccagtgtgatggtctttggagatgaggcctttggcaggtgattagagctagatgaggtcatgagagggaggccctcatgaaaggctcagtggcctgataagaagaaacaccagagagcttgctctgtttctctgcctacctggcgcacacatacagaagaggtgatatgaccacacagcaacatggtggccaccagcaagctaggagagggatcagaatgaaacctattttgctggcaccttgatcttgaaattctagcctccagaactgtgagaaataaaattcttttattgaagcca

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