Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DNAJC12P1
Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr10). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:91896702-91896899  UCSC
Coordinates (T2T) chr10:92778785-92778982  UCSC
Coordinates (hg19) chr10:93656459-93656656  UCSC
Strand +
Parental Sequence NM_201262.2
Parental seq. overlap 162 bp
Parental seq. overlap (%) 20.5%
Genomic Region Intergenic
Retrocopy Summary DNAJC12P1, located on chr10:91896702-91896899, is a retrocopy of the parental gene DNAJC12. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DNAJC12
Full Name DnaJ heat shock protein family (Hsp40) member C12
Also known as HPANBH4|JDP1
Coordinate chr10:67796665-67838188
Strand -
Gene summary This gene encodes a member of a subclass of the HSP40/DnaJ protein family. Members of this family of proteins are associated with complex assembly, protein folding, and export. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes DNAJC12P1
Bonobo Pan paniscus DNAJC12P1
Orangutan Pongo abelii DNAJC12P1
Gibbon Nomascus leucogenys DNAJC12P1
Green monkey Chlorocebus sabaeus DNAJC12P1
Crab-eating macaque Macaca fascicularis DNAJC12P1
Rhesus Macaca mulatta DNAJC12P1
Baboon Papio anubis DNAJC12P1
Gorilla Gorilla gorilla Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>DNAJC12P1
CCTGGCAGAATTTAAGTTCAGAGCTGTGGAATGCCACCCCAACAAGCATCTGAAAATTCCAAAGCAATGGAGACTGTTCAGAAACCGCAGAAGGCAAAGGAGATTCTGACCAATGAAGAGAGTTGTGCCCACTATCATCACCGGTGAAGGAGCCAGATATTGATGCCAGTCCTGCAGTGGGAAGC
>NM_201262.2
AGAGTTTACAAAGGTCTAGGATGACATCTGGTGTATTGACTGTGGCCAGTCTTAAAGCTAGTTTTTGCTATGTGGAACATGCTGCTCTAATTCAGATTTAAAGAGTTTCTTCCTGTTAATTCGAAGCTCACTGTGCCTCTTGTTTCCGAGGGAAGAAGGACTGATTAAGTCATCTAAATGGATGCAATACTGAATTACAGGTCAGAAGATACTGAAGATTACTACACATTACTGGGATGTGATGAACTATCTTCGGTTGAACAAATCCTGGCAGAATTTAAAGTCAGAGCTCTGGAATGTCACCCAGACAAGCATCCTGAAAACCCCAAAGCTGTGGAGACTTTTCAGAAACTGCAGAAGGCAAAGGAGATTCTGACCAATGAAGAGAGTCGAGCCCGCTATGACCACTGGCGAAGGAGCCAGATGTCGATGCCATTCCAGCAGTGGGAAGCTTTGAATGACTCAGTGAAGACGGTGGGTTTCTCGCTGGGTGCGACGTGAATTTGTGAAGCTCAGGATGCCCATGGATTAGACTCATGTAGTAGCTTAAAGAGTCATTAGGCGATAGGAGGGAGAAAACCAAGAAGTTAGCAGAGTCTGGATATAATTCAGTGTCCGTAAATCCCATGAAGAGAAGCTCATCAGAATAAAGGCAATGAATTTGTGCCAGAAGAGCCTGTGACTACATTTCTTTCAATCTCTTTGGCTGTTTGTTTCAGTATACACACTCCCTGTTATTGCTTACTATTTTATGAGCTCTAATAAATGTACTTCTCAAGTTGCTCATGAA

Publications

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