Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name FIBPP1
Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:95758924-95759085  UCSC
Coordinates (T2T) chr10:96638027-96638188  UCSC
Coordinates (hg19) chr10:97518681-97518842  UCSC
Strand -
Parental Sequence NM_004214.5
Parental seq. overlap 139 bp
Parental seq. overlap (%) 10.2%
Genomic Region Intragenic (ENTPD1)
Retrocopy Summary FIBPP1, located on chr10:95758924-95759085, is a retrocopy of the parental gene FIBP. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name FIBP
Full Name FGF1 intracellular binding protein
Also known as FGFIBP|FIBP-1|TROFAS
Coordinate chr11:65883740-65888471
Strand -
Gene summary Acidic fibroblast growth factor is mitogenic for a variety of different cell types and acts by stimulating mitogenesis or inducing morphological changes and differentiation. The FIBP protein is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF). It is postulated that FIBP may be involved in the mitogenic action of aFGF. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes FIBPP1
Gorilla Gorilla gorilla FIBPP1
Orangutan Pongo abelii FIBPP1
Gibbon Nomascus leucogenys FIBPP1
Green monkey Chlorocebus sabaeus FIBPP1
Crab-eating macaque Macaca fascicularis FIBPP1
Rhesus Macaca mulatta FIBPP1
Baboon Papio anubis FIBPP1
Golden snub-nosed monkey Rhinopithecus roxellana FIBPP1
Marmoset Callithrix jacchus FIBPP1
Mouse lemur Microcebus murinus FIBPP1
Bonobo Pan paniscus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>FIBPP1
CTCAAGGTGCTAATGGCTGACAAGGACCTTTTGGACTTGCACAAGAGCCTGGTGTGTACCACCTTCTAAGGAAAGCTTGGGATGTTCTCTGAGAGGAACACCAAATTCAAGAACCTGTCCCAGGGGCTGATGAATGTGGCTGCCAAGCTGACCCACAATAAG
>NM_004214.5
AGTCCCGAGCAGTGCTCGCTCCTGCTCGGGGCGCTGCGGCCCCGGGCGTCGCCATGACCAGTGAGCTGGACATCTTCGTGGGGAACACGACCCTTATCGACGAGGACGTGTATCGCCTCTGGCTCGATGGTTACTCGGTGACCGACGCGGTGGCCCTGCGGGTGCGCTCGGGAATCCTGGAGCAGACTGGCGCCACGGCAGCGGTGCTGCAGAGCGACACCATGGACCATTACCGCACCTTCCACATGCTCGAGCGGCTGCTGCATGCGCCGCCCAAGCTACTGCACCAGCTCATCTTCCAGATTCCGCCCTCCCGGCAGGCACTACTCATCGAGAGGTACTATGCCTTTGATGAGGCCTTTGTTCGGGAGGTGCTGGGCAAGAAGCTGTCCAAAGGCACCAAGAAAGACCTGGATGACATCAGCACCAAAACAGGCATCACCCTCAAGAGCTGCCGGAGACAGTTTGACAACTTTAAACGGGTCTTCAAGGTGGTAGAGGAAATGCGGGGCTCCCTGGTGGACAATATTCAGCAACACTTCCTCCTCTCTGACCGGTTGGCCAGGGACTATGCAGCCATCGTCTTCTTTGCTAACAACCGCTTTGAGACAGGGAAGAAAAAACTGCAGTATCTGAGCTTCGGTGACTTTGCCTTCTGCGCTGAGCTCATGATCCAAAACTGGACCCTTGGAGCCGTCGACTCACAGATGGATGACATGGACATGGACTTAGACAAGGAATTTCTCCAGGACTTGAAGGAGCTCAAGGTGCTAGTGGCTGACAAGGACCTTCTGGACCTGCACAAGAGCCTGGTGTGCACTGCTCTCCGGGGAAAGCTGGGCGTCTTCTCTGAGATGGAAGCCAACTTCAAGAACCTGTCCCGGGGGCTGGTGAACGTGGCCGCCAAGCTGACCCACAATAAAGATGTCAGAGACCTGTTTGTGGACCTCGTGGAGAAGTTTGTGGAACCCTGCCGCTCCGACCACTGGCCACTCAGCGACGTGCGGTTCTTCCTGAATCAGTATTCAGCGTCTGTCCACTCCCTCGATGGCTTCCGACACCAGGCCCTCTGGGACCGCTACATGGGCACCCTCCGCGGCTGCCTCCTGCGCCTGTATCATGACTGAGGTGCCTCCCAACGCTCCGCCCACGCTGACAATAAAGTTGCTCTGAGTTTGGAGACTGGTCCTCGCTCCGGGGAGCAAGTGGGGGGCGTGCAGATGTGCCTGTGTCTGTCTCTGAGCACCTGGTGTCCGTGTACAAGGATGGATGTGTACAGTGGCTCCTTGGGAACTGAGACATATCTCAGGGAATGGTGTCTGTGCTCAGCCCATCCACCAGAAGAGTCTGCTCACAAGCCA

Publications

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