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Summary

Retrocopy Name EBAG9P1
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Plot displaying the genomic locations of a retrocopy (in chr10) and its respective parental gene (in chr8). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr10:99697017-99697962  UCSC
Coordinates (T2T) chr10:100580022-100580967  UCSC
Coordinates (hg19) chr10:101456774-101457719  UCSC
Strand -
Parental Sequence NM_001278938.2
Parental seq. overlap 786 bp
Parental seq. overlap (%) 29.5%
Genomic Region Intragenic (COX15)
Intragenic (ENTPD7)
Retrocopy Summary EBAG9P1, located on chr10:99697017-99697962, is a retrocopy of the parental gene EBAG9. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name EBAG9
Full Name estrogen receptor binding site associated antigen 9
Also known as EB9|PDAF
Coordinate chr8:109539702-109565996
Strand +
Gene summary This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor, which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10. [provided by RefSeq, Jul 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes EBAG9P1
Bonobo Pan paniscus EBAG9P1
Gorilla Gorilla gorilla EBAG9P1
Orangutan Pongo abelii EBAG9P1
Gibbon Nomascus leucogenys EBAG9P1
Green monkey Chlorocebus sabaeus EBAG9P1
Crab-eating macaque Macaca fascicularis EBAG9P1
Rhesus Macaca mulatta EBAG9P1
Baboon Papio anubis EBAG9P1
Golden snub-nosed monkey Rhinopithecus roxellana EBAG9P1
Marmoset Callithrix jacchus HNRNPCP18
Mouse lemur Microcebus murinus EBAG9P1
Horse Equus caballus EBAG9P1
Velvety free-tailed bat Molossus molossus EBAG9P1
Greater horseshoe bat Rhinolophus ferrumequinum EBAG9P1
Egyptian rousette Rousettus aegyptiacus EBAG9P1
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Adipose SubcutaneousMuscle SkeletalArtery TibialArtery CoronaryHeart Atrial AppendageAdipose VisceralUterusVaginaBreast Mammary TissueSkin Not Sun ExposedMinor Salivary GlandBrain CortexAdrenal GlandThyroidLungSpleenPancreasEsophagus MuscularisEsophagus MucosaEsophagus Gastroesophageal JunctionStomachColon SigmoidSmall Intestine Terminal IleumColon TransverseProstateTestisNerve TibialSkin Sun ExposedHeart Left VentricleBrain CerebellumWhole BloodArtery AortaPituitaryBrain Frontal CortexBrain CaudateBrain Nucleus AccumbensBrain PutamenBrain HypothalamusBrain Spinal CordBrain HippocampusBrain Anterior Cingulate CortexOvaryBrain Cerebellar HemisphereLiverBrain Substantia NigraKidney CortexBrain AmygdalaCervix EctocervixFallopian TubeCervix EndocervixBladderKidney Medulla00.51
log10(TPM+1)

Massive Mining of Publicly Available RNA-seq Data from Human and Mouse - (ARCHS4)

Related Sequence

>EBAG9P1
TTTGATTCCCACCATGGCCGTAACACAGGTCCAGTTATTTTGAGTTTATACTTGCCTAGCAACCATATTCTCATTCCTCAAAATGATGAGTATGAAGATCTGTCCAAGGACAGAAATTAAGTTGGGGTCCAAGTAACTTTGCCAATTGCAGTTAATTATTCATCAGTTCCTAAACAGACAGATGTTGAAGAGTGGACTTCTTAGAATGAGGATGCGCCCACAGGTGTAAAGACCGAGGGTGAGAATGGAATGAGGCAGTACAACAGAACACTTTACAACAACTGGAACCGACTATTTTAAGGATGTGACACCAACTGTAAGGAAAACTCAGAAAATTGTTATTGAGAAGAGACAATGATCATTTTGCCATCTCAGGAAATAGGTTAATAGACTGGCAGCTACACAAGATATGCCTTTTACTCATCAGTCACCTGATGTAGGTGACTTAGCTACTTGGCAAGAAAATACCAACGCATGGGAAGAAGATGCAGTCTGGCAAGAAGTAGTTTGGAGGCAGCAGAAAACAGCAGACAGAAAAGAAAGGAGTAGAACAAAAGAAGAAAATGGAAAAGGAAGCACAGCAGCTAATGAAGAAGGAAAACCAAAACTGGTGTGAAACTTTCAAAACAAATGATCTTCAAACATCATGGTGCCTGCAGGAGACATCTGAGCACCTCAACCCAAGCAATGTTTGTATAGATTTAGGAGTACTTTCAGAATACAAACACACCACTTGATTTTAATGCATTAGTCAATCATCCAGGGCACCAGGATTCTCCCAAAGCACCTTGAACTCCTAGAGACTAAGACTTACAAAAACAAAATAGACTTATGGGACAATATTTTCTTCAACATGCCGTAAATATAAGATAATTGATTGCTGTGGATAAATTATTACAAACGGGGTATACCAGTACTTCTTCAAGCTAGTGTTCGTAGCTAAATG
>NM_001278938.2
AGGCGTGCAGCATTCGCCATGCTCCGCTCACGCGTGGGAGACTGGGCTGTGGGGTACCGGCCCGGAAAGCACGCAGCCTCCAAAGCCGCCTTCCTCAGGGAAATTTGCGTGACCTTACTGCCCTCCGTCTACAGGCCTTGTACCTCTCCAGGCCGATTTTTCCACAATTTAAATCTCAGTTCACCTGGTATCCAGCTCCAGCAACTTAGAGCGTTTCACGTCACGCCGGGCGCCAGGCGTCGGCTTGTATAACCTGAAAACGCTCCTGTTTTTCTCATCTGTGCAGTGGGTATGATTTTTTTTTCATCAACAAATTTCACGTGGGTAATCTGAAATGAAACCACTTAAGTTATGAAACTCTTTCCTTTTGAGTTATTCTGGAGACCTTACTCCGCCTTCGGAACCGCCCCAGTGGTGTCACATACTTGAGGGCCTGACTCTCGGTTGCCAGACATGGCACAGAATGTTCGATTTTACTACCAGCTCTCACACTCCGCTTCTGTTTCCCCTTCTCTTACGGGCCGCTGCTCAAACCTTTATTTATCAAATTTAAGTTTTGATTCCCACCATGGCCATCACCCAGTTTCGGTTATTTAAATTTTGTACCTGCCTAGCAACAGTATTCTCATTCCTAAAGAGATTAATATGCAGATCTGGCAGAGGACGGAAATTAAGTGGAGACCAAATAACTTTGCCAACTACAGTTGATTATTCATCAGTTCCTAAGCAGACAGATGTTGAAGAGTGGACTTCCTGGGATGAAGATGCACCCACCAGTGTAAAGATCGAAGGAGGGAATGGGAATGTGGCAACACAACAAAATTCTTTGGAACAACTGGAACCTGACTATTTTAAGGACATGACACCAACTATTAGGAAAACTCAGAAAATTGTTATTAAGAAGAGAGAACCATTGAATTTTGGCATCCCAGATGGGAGCACAGGTTTCTCTAGTAGATTAGCAGCTACACAAGATCTGCCTTTTATTCATCAGTCTTCTGAATTAGGTGACTTAGATACCTGGCAGGAAAATACCAATGCATGGGAAGAAGAAGAAGATGCAGCCTGGCAAGCAGAAGAAGTTCTGAGACAGCAGAAACTAGCAGACAGAGAAAAGAGAGCAGCCGAACAACAAAGGAAGAAAATGGAAAAGGAAGCACAACGGCTAATGAAGAAGGAACAAAACAAAATTGGTGTGAAACTTTCATAACACATGTTCAAATTTTATCATGCCAGTAGGAGAAATCTCAGCTCCACAACCCAAGCAACATTTGTATGGATTTAAGAGTATTTTAAGAAGACATACTGCTTGATTTTAATACATTGATCAGGCCATCCAGGACACCACGATTCTCCCAAAGTACCTTGAACTCTTAGTGATTGAGACTCAAAAAAACAAAAAAGACTTGAGACAATGTTTTCTTCAACATGCTCCAAATATAAGACATTTGTTTGCTGTACAGAAAGTATCACAAATGGAATATATCAGTACCTCTCAAGCTAGTGTTTCTAGCTAAATAAATGGGTGTATATAATTTTATGGTGGAAAAGAACTGTACTGTCTGTTATGATTTCCTTCAATGTGCATAATGATAAAATAAATAATTTTAATATTCTTTTGTTTCCATGGTTACCTGACCTAAATTAGATAAATTGTAGGGCTTTAGCTTTCTTATTTTTGTCAAAAGTTGGTGTTGACATACATTCCCTCTAATTTGAACTGGTATTGTTTACGTTTGATACAACATTAAGGAATTTGATGATTTTCATTTCATGAAAATGACATTAAATGCAATAATTTTACTTATCATAAACATTTTGTACATCATTATTTTCTTTTGGATTAGTGTTGTCATACATGTAATTTATATCACATGTATAAACATTGAAAATCAACTAAAATGACATTTGTTCTACATTATAACTTGTGAGTTTCAAGAACTAGTATTAGTAGTTTTTTCCTTTCATTATAGATTGTAAGATGTTGTGGTATCTTTGAGTGCCTTAGTTCTTCCTTCCTCCCAAAAGCCATTAATTTACAAATGCTTAAAGCCATCAGGTCAAATATTTCAAAGCCTTTAGATGATTTCTGTACTAGCTTTAGATGTCTGACGTTATGTAGGTTACCTGTGTTCTTGGCTAGGAAAACATTATTGATTCATTAAATCATAAAGGTGGGAATAATAATCTTTTATTTATGATGTTGATTGGCTCCAAAATAGTCTTAAGGAAATAAATACTGGGTCTGTAGGGGAAAAGTAGACTTCATAGTTTAAAATCCCATTAACCTTTTCACCGCAGTTGAAATGCATCCAGCCTGATTTTCCTATCATTTTGGAATTTTTAAGGATTTTTACTTTCTTAAGTTACTGCCTAGAATCAACATTCGGTGAGATTTTGAAATGTCATAGATACTGTACAGGCCAAACCTTACTAATTTATTTTACTTAAAGTGATATTTTATAGAAAAATCATAAGTTATACAATGAGAACCCTTTAAGCCCTTAGCCTAAGCTTTCAGACTAAATGTGATTATAGAATAAGATGAAAGTTAACTTTGGTACAGAGCTTTTTATAGCCCCAAATTATATTTCCAGTTATTATATTCATTAGAATTTCTGCTAATAAACTCCCAACTTAAATAGAA

Publications

PMID - Link Title
No publications available for this retrocopy