Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name AP2B1P2
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr17). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:103926565-103928796  UCSC
Coordinates (T2T) chr1:103963716-103965947  UCSC
Coordinates (hg19) chr1:104469187-104471418  UCSC
Strand +
Parental Sequence NM_001282.3
Parental seq. overlap 1512 bp
Parental seq. overlap (%) 26.4%
Genomic Region Intergenic
Retrocopy Summary AP2B1P2, located on chr1:103926565-103928796, is a retrocopy of the parental gene AP2B1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name AP2B1
Full Name adaptor related protein complex 2 subunit beta 1
Also known as ADTB2|AP105B|AP2-BETA|CLAPB1
Coordinate chr17:35587265-35726413
Strand +
Gene summary The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes AP2B1P1
Bonobo Pan paniscus AP2B1P1
Gorilla Gorilla gorilla AP2B1P1
Orangutan Pongo abelii AP2B1P1
Gibbon Nomascus leucogenys AP2B1P2
Green monkey Chlorocebus sabaeus AP2B1P1
Crab-eating macaque Macaca fascicularis AP2B1P1
Rhesus Macaca mulatta AP2B1P1
Baboon Papio anubis AP2B1P1
Golden snub-nosed monkey Rhinopithecus roxellana AP2B1P2
Marmoset Callithrix jacchus AP2B1P2
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>AP2B1P2
tACAGAATTCTGATAATCCTGGCCTTTGAGACGGGGGCTATATTTATTGGTGTCTTCTCTCAACTGACTCAGTCACAGCTAAACAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACAGATCTTATTGAGCTAACTCTACTGGAGAGCTCATGTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCAAATATTTTTGTGGAAGGAAGTCATGGAATCCATTGTAAATAGTTGCCAATTCATCATGGGAGTACTGATTCAGGTGACAGCCCTGTTGGTACCACTGCAACTAACCTGAAACAGCCTCAGGTTATCCCCTCATAAGGTAATCTTCTCAGGGGTCTTTTAAACCTTGACCTCAGTCAACCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGAGCAGTGGATCTCTTGGGAGGAGGATAAGATAGTCTGGTGGGACAATCCTTCATCCTATGATGGGTGTCTGCAACCTTTGTTTCTTCATCTACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCCACAGGGATAGGCATGGCACCTGGTGGGTATGTGGCTCCTAAGGCTATTTCTGGCTACCTGCATTACAGGATAAAGGCTTAGAGATTTCAGGAACATTGAGTCACCACCAAGGGCACATCTATATGGAAATGAACTTCACCAATACAGCTCTGCAGCATATGACAGATTTTGTAATCTAGTTTAACAAGAATAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAACATTGATGTCTCCCTGCCTCTCAATACTTTGGGCCTAGTCATGAAGATGACTGAATAACCTGCAGGTGGCTGTGAAAAACAATATTGATGTCTTCTACTTCAGTCACCTCACCCCACCTCACCCCAATCAGTGTGCTTTTTAGAAGATGGCAAAATGGAGCACCAGGTCTTTCTTGCAACAGGGAAGGATATTCCCAATGAAATGAACTTCAGTTTTAGATTAACGAATGTCATTTAAATGCTGACATTGTTTCCAGCAAGTTGCAAAACAATAATGTTTATACTATTGCCAAGAGTAATGTGGAAGGGCAGGACATGGTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCTGAGCTATGTATCCACCCAGGAAACCCCCATTATATGCTGTCACTGAAGTGCAGAGCTCCTGAAGTCTCCCAATACATATCAAGTCTAGGACAGCATTTTGAAAAGCTAACAAGACTTGTCCACTACCTTCCAATCACGCTGTGATCGGTGCAAGCCAAGAACTCTTTTTTTTTCTTTTAATGATTTCCAGTAAGAAAATGAATAATGATaCTCTTAACTGGAAGATGTGTTGCTGTGTAGAATCTGAACCCAAACATACTGAGGTAACCCAGCAAGGTAGTAACTAGTCTAACCTGTCTAACCTGTGCTAACATTAGAGTACAACCTGTTGGATACTTTTAGCATCCTGTGAACATTGGTAACCACTGCTTCAGTCACCTCCTAACTCTTGCCACCTGCTGCTCTTGTCTGTGGTTACTTGTGGGCTTCTCCGTGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGGGTAGTTTGGTATTTTGTAATTGAGAGCTCATTCCAAAAGCAGAAAAAGACAACAAATGCTAAAGCAAGAAAGTGTCACTGAAA
>NM_001282.3
AGACCTAGAAAAGAATCGTGACGGGCAGGAAACCATTACACCACCACCTGGGCTGTGCTCTccggctcccgccgccacccccgccctcgccttcgcctccgcctccgGTGCACATTAAAGATCCAAAGTCATGACTGACTCCAAGTATTTCACAACCAATAAAAAAGGAGAAATATTTGAACTAAAAGCTGAACTCAACAATGAAAAGAAAGAAAAGAGAAAGGAGGCTGTGAAGAAAGTGATTGCTGCTATGACCGTGGGGAAGGATGTTAGttctctctttcCAGACGTAGTGAACTGTATGCAGACTGACAATCTGGAACTAAAGAAGCTTGTGTATCTCTACTTGATGAACTACGCCAAGAGTCAGCCAGACATGGCCATCATGGCTGTAAACAGCTTTGTGAAGGACTGTGAAGATCCTAATCCTTTGATTCGAGCCTTGGCAGTCAGAACCATGGGGTGCATCCGGGTAGACAAAATTACAGAATATCTCTGTGAGCCGCTCCGCAAGTGCTTGAAGGATGAGGATCCCTATGTTCGGAAAACAGCAGCAGTCTGCGTGGCAAAACTCCATGATATCAATGCCCAAATGGTGGAAGATCAGGGATTTCTGGATTCTCTACGGGATCTCATAGCAGATTCAAATCCAATGGTGGTGGCTAATGCCGTAGCGGCATTATCTGAAATCAGTGAGTCTCACCCAAACAGCAACTTACTTGATCTGAACCCACAGAACATTAATAAGCTGCTGACAGCCCTGAATGAATGCACTGAATGGGGCCAGATTTTCATCCTGGACTGCCTGTCTAATTACAACCCTAAAGATGATCGGGAGGCTCAGAGCATCTGTGAGCGGGTAACTCCCCGGCTATCCCATGCCAACTCAGCAGTGGTGCTTTCAGCGGTAAAAGTCCTAATGAAGTTTCTAGAATTGTTACCTAAGGATTCTGACTACTACAATATGCTGCTGAAGAAGTTAGCCCCTCCACTTGTCACTTTGCTGTCTGGGGAGCCAGAAGTGCAGTATGTCGCCCTGAGGAACATCAACTTAATTGTCCAGAAAAGGCCTGAAATCTTGAAGCAGGAAATCAAAGTCTTCTTTGTGAAGTACAATGATCCCATCTATGTTAAACTAGAGAAGTTGGACATCATGATTCGTTTGGCATCTCAAGCCAACATTGCTCAGGTTCTGGCAGAACTGAAAGAATATGCTACAGAGGTGGATGTTGACTTTGTTCGAAAAGCTGTGCGGGCCATTGGACGGTGTGCCATCAAGGTGGAGCAATCTGCAGAGCGCTGTGTAAGCACATTGCTTGATCTAATCCAGACCAAAGTGAATTATGTGGTCCAAGAAGCAATTGTTGTCATCAGGGACATCTTCCGCAAATACCCCAACAAGTATGAAAGTATCATCGCCACTCTGTGTGAGAACTTAGACTCGCTGGATGAGCCAGATGCTCGAGCAGCTATGATTTGGATTGTGGGAGAATATGCTGAAAGAATTGACAATGCAGATGAGTTACTAGAAAGCTTCCTGGAGGGTTTTCACGATGAAAGCACCCAGGTGCAGCTCACTCTGCTTACTGCCATAGTGAAGCTGTTTCTCAAGAAACCATCAGAAACACAGGAGCTAGTCCAGCAGGTCTTGAGTTTGGCAACACAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCAACTGACCCTGTTACAGCTAAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGATGAGCTAATCTGCCACATTGGTTCTTTGGCCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAACACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGACAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATCCCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGTCCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGAGCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGGTGGGACAATCCTTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCCACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGAACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTTAACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAACAAATATTAAAGCAAGGAAAAGTGTAACTGAAACACTGCACTTTACTGTTTTATACTTTTGTACATATGAGAAATCAAGGGATTAGTGCAACCAGTAGAAAGCATTGAAATGACTGTCATTAACCACACAGTCCTGGAGGCAGAGATGCAGTTACCTACCCTAGCTTTTGATGGGTTCTCTTACCTGTAGTAGCCTTATCCCTGGTCATTTGGATTTTCAGTTTGCTTTTTTCTTTTTTTCCCCTCCAAACTCCTTTTCCTTGGCCAAGCCTTCATGCTTCCCCCTTTCCATATTATAATCTCATTTGATTGCTCTGCAGTTGGGAACGGTGATCTTCTTGAATGATGTTTCAGTGTGCAAAAACTATAGAGCCTGTCAGCACCAAAGCTGACAGAAGTTATACCTTACTCCTTTCCTTTCCCCTGAACAAACCTGCTAATCCCACTAATTCAGGAATTTGAGTAGAGATGGGGAACAAGAACCCAGATGCTGTCCCCTCACCCCCTCTCCTGTATTTCTCAGGTCCAGTTCAaatctaaaattctacttttagagttgaaacagagtaataacttatctaaccctcttttcctacaaaggagaaagataaaaggcacaaaggttaccgccaaggcccgtcagctgtgtagtggcaaagccgagaccgagtctcctaagtccccgtcagtgtggttttcaccacaggactgtctcTTGTCGTTTTCCCCTAATGCCTTCTCCTGCCTTTTCTGTGCCTAGTTTTTGGCTCTTCACATATTCCATATTGATTTTGACGCTCTGTATATTGGCATCAGGTGGCAGCTGAATATCTTTTGAATTACTCGAAGGTAAAGCCAGATGCCAGAATGAAGGTGTAGCCAGTGTTTCCCATATGCCCCTGGAGCCCCACTTATTGAGGCCAGCAGAATAGGTGCAGAGATGAAGTGAGCTTAGAGATGTTGCAAATGCTCTTTATCCCTTCAGCTCTCTGATCTGCTCTTTCTTCATGATACTTAGTCTGCAGGGCATATTAAGATCATCCCAGAGGTTCAGGCAGTTCCTGTCATCTCTGAAAAGACTGGGGGATATGAAATCTTCCCCCTACCCCACTTAATGCGTTGGATATGATTTTTCAAAGAATGCTTCATGCCCAAAATACCAGCCTGTTTAGCAGTGTTACACTGTTTGATCTGCGGGCACTTGTTGCATTGCCTGGCACCCAATATTCAGGGTCCATGACTAAGACTGGTCTTCTCAGATGCCCTGCTTAAATCAGGGGCACTTCAGGCTCCACAGGCGTCATGTTGGACTGAGACCTAACTCACTGGACTCAGAGGAGGAATCGTGGAAAACAAGAGCAAAACTACCCCACACCCCTATTTCATGTCTGAAATAACCCTGTTTCATACCAGTTGCAAAGCTTGTGGGGAGCGGTCCCACAAAGCACTTTCTTAAACCTTGAGAATCTCCAAGAGAAAAATATTTGGGGAAGGAGGGAGGAAATATGTCCCTTGCACACCACCCCTGAAGCACATGGCAGTAGGAAACAGCATAGGATTGTATGTGGGAGGTGGATAGGTCGGTGATGTGTGGAGCGGAAAAGCAGGTTGGTAAAGTTCCCTTCTTGGGACTTATTCCTGGAGTCAGTGGATACAAGTAGTGCAGAAGGTTCACACTGCAAATAGTGTTCTCATCTCAAAGCAAACTATCATTCCAGAAGGAAAAGTGTGTCAGGGCAAGCAGACAACACAATTTCCTATCAGAATATGTCCCTCAACCCCCGAAACAAGGCTTCTCTCAGCCTCCCCACCAGTGATGGATAACAGCTCCTATTCTCAGCTGACCTGACTGAGCCAACCCATGAACTCTTCACTCCTTGGGGAAGCCACCTCCCATCACACCCCTGAGCAGAGTTAGGGAGGAATTCTACTTCCCATAAAAGGACCTCTCCTGAGAGGCAAAACCTGTTGCCTCCACCACGGCTTCCCTCTTGGCTCATTCCAAGCTTGGCCAAATTGGGGAAGTGGGATGGAGGTTGCCCTGCATCCCCCCTCCTCTGCCTGAGTGTGTCTTTGTAATGTCAGCTGGCATCATACAAAGAGCAGGAGAAGCAAACACCCAGAACTCTTTTGCTGGTCAGAGATTCCCTGAGTGTCTGTCCTCACCCAAGCCTGCTCTGTGTCTGTGTTGTGAAGCTTGAGACTCTGGAAAGAAATGGGGAGGGGGGGCAGGGGAAATGTTGCCCTAAGAATGCTTCTCATTCCTCTGTTCTTATTGGGTCCTGTTTTTCGGGAGGGTGGGGGTTGGGGGAAGCTTGACCTTGTGTCTTCGTCAATAAACTCACATTTACACAAAA

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