Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name OOEPP3
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:106544154-106544727  UCSC
Coordinates (T2T) chr1:106581609-106582182  UCSC
Coordinates (hg19) chr1:107086776-107087349  UCSC
Strand -
Parental Sequence NM_001080507.3
Parental seq. overlap 477 bp
Parental seq. overlap (%) 60.3%
Genomic Region Intergenic
Retrocopy Summary OOEPP3, located on chr1:106544154-106544727, is a retrocopy of the parental gene OOEP. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name OOEP
Full Name oocyte expressed protein
Also known as C6orf156|FLOPED|HOEP19|KHDC2
Coordinate chr6:73368555-73369897
Strand -
Gene summary Predicted to enable RNA binding activity. Predicted to be involved in several processes, including cytoskeleton organization; positive regulation of double-strand break repair via homologous recombination; and positive regulation of meiotic nuclear division. Predicted to act upstream of or within several processes, including embryo implantation; in utero embryonic development; and protein phosphorylation. Located in cytoplasm and nucleus. Part of subcortical maternal complex. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes OOEPP1
Bonobo Pan paniscus OOEPP1
Gorilla Gorilla gorilla OOEPP1
Orangutan Pongo abelii OOEPP1
Green monkey Chlorocebus sabaeus OOEPP3
Crab-eating macaque Macaca fascicularis OOEPP1
Rhesus Macaca mulatta OOEPP1
Baboon Papio anubis OOEPP1
Golden snub-nosed monkey Rhinopithecus roxellana OOEPP3
Marmoset Callithrix jacchus OOEPP2
Gibbon Nomascus leucogenys Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>OOEPP3
GACTCCGTCTCACTCCATGGAGAAGCTGCTTAGGTTACCACTTCCCCACCACAGATTCTCATGGGCTCTGGTGGTTTCTGGTGCAGGAACTGAGAGGCCCTTCCGTGTTCTACCTGGAGGTATGGCTGGCAGATGTGACCTTTGAGGCAGACTGAGCCATAATTCCAGGACTGGAGTGGATGAGCCTGTCCCTGTTGATGGTGGACATAGTGGACTCTGGGATCCAAGTCAAAATCACAATTTTTGGACAACTCTGTGTATGGAATCGGGTAAAGTGCATGTTCCTGTGCTTGACATGGCTTCACCAACAATCATGCTTAAGCTGAGAAAATAAAACACATTGAGGAGAATTTGAAGGCCTCTACAGTCCTCAGCATCCTGTTGCTTAAGACAACACAATTATTGTCAGGTGCATTTTGAAAACTGTCCAGCTTTTGCTGCTAAAGTTGAAGAGAAACAAGTACAGCATTCCCAAATCTCTGTATTCGTTTTTCCTGTGACTTGATGAATATGGTTTATTTTGTTGCAAGAGTGAGTTTGAAAAACTATTTTAATAAAGAAATGGCTATTTTGT
>NM_001080507.3
GGAGCGGGTCGAATATGGTAAAAGAGAGCCCGAGCTTCGCGCCTGGGTCTGGAAGAGGTCTTGCGAAAGCCGCCTCGAGCGCGCTCCGCGGCTGCTGGTCCCAGTATGGTCGATGATGCTGGTGCCGCTGAGTCCCAGCGGGGCAAACAGACTCCGGCCCACTCCCTGGAGCAGCTGCGTAGGTTACCACTTCCGCCGCCACAGATTCGCATCCGGCCCTGGTGGTTTCCGGTGCAGGAACTGAGAGACCCTTTGGTGTTCTACCTAGAGGCATGGCTGGCAGACGAGCTCTTTGGCCCAGACCGAGCCATAATTCCAGAAATGGAGTGGACGAGCCAGGCCCTGCTGACAGTGGACATAGTGGACTCAGGGAACCTAGTCGAAATCACCGTTTTCGGGCGGCCCCGTGTACAGAATCGGGTGAAGAGCATGCTCCTGTGCCTGGCATGGTTTCACCGAGAACATCGTGCCCGAGCTGAGAAGATGAAACACCTTGAGAAGAACTTGAAGGCCCATGCATCAGACCCCCACTCTCCCCAGGATCCTGTTGCTTAAGACAACATAGTTACTGTTGGGAACATCTTAACTTTCTAACTTTTGCTGCTAAAGTTGAAGAAAAGCAAGTATAGCATTCTTAAATCCCCGTATTCCTTTTTCCTGTGTCTTGATGGATTGTGGTTTATTTTGTTGCAAGAGTGAGTTTGAACTATTCTAATAAAGAAATGGCTATTTTGCCAAAAGCATTAAGATCTTCACACACTTATAATAAAGCAAATTTATAAAA

Publications

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