Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name CCNT2P1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:111014663-111015545  UCSC
Coordinates (T2T) chr1:111029485-111030367  UCSC
Coordinates (hg19) chr1:111557285-111558167  UCSC
Strand -
Parental Sequence NM_058241.3
Parental seq. overlap 630 bp
Parental seq. overlap (%) 8.9%
Genomic Region Intergenic
Retrocopy Summary CCNT2P1, located on chr1:111014663-111015545, is a retrocopy of the parental gene CCNT2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CCNT2
Full Name cyclin T2
Also known as CYCT2
Coordinate chr2:134918810-134959342
Strand +
Gene summary The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CCNT2P1
Bonobo Pan paniscus CCNT2P1
Gorilla Gorilla gorilla CCNT2P1
Orangutan Pongo abelii CCNT2P1
Crab-eating macaque Macaca fascicularis CCNT2P1
Rhesus Macaca mulatta CCNT2P1
Baboon Papio anubis CCNT2P1
Golden snub-nosed monkey Rhinopithecus roxellana CCNT2P1
Marmoset Callithrix jacchus CCNT2P1
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>CCNT2P1
GGAGGAAGAAGTGTCATGGTGCCAGGCGTGGAGCTTCTTCTCATTGGCTCTTACTAGGGAACAGCTGGAAAGCAGGCCAAGTAGCCACTGTGAAGTGCAGGTCGATAAAGAGGTCCCATACTGCCAGCAGGTGGCCAACCTCATCCAAGACATTGGATAGCATCTCAATGTCTCTCAGCTTACAGTAAACACTGCAATTGTTTGTATGTACTATTCTTTCACTAAATTCAGTAGGAATCCTTGATGGAGTAAAATGTCTGCAGACTGACTAGGAGGCAATGTGAATGAATTAGTGGATTTCACCAGAAACTTTGGAAGAGTGCTGGGTATCAGTGTTGCACTAAAGGAAGATGAAAATTGAGCTCTCTTTAGAGGAAACAAATACTTCTGTGAGGAGTGTGGGTAATACTGTCAACCATGTAATTCTTTGGCAGTGAAAGGGGAGGAACAGGCTCAGAAACTTGAACATGTTATTAAAGTAGCACATGCTTGTCTTCACTCCCTACAGTGCTGGATACTAAATGTGGTACTTACTTTCAACAGACTCAAGAACTGGTTTTAATTGAAACCATAACCCTACAAACACCAGATTTTGAGATCAGCATTGAACATCCACAATCAGATGTGGTAAAACATACCAAGTTAGTAAGGGCAAGCAAGGATTTGACACAGACATCTTATTTGATGGCTATAAACAGTCTGCATCTCACAACCTTCTCTCTTCAGTACAAACCAACAGTGATAGCATATGTATACATTCATTTGACTTGCAAATGATCCCATTGAGAGATTCCTGCATCAATTGATGGAAAGCCTTGGTGGTAATATGTGGATTCTACAGTTACTCTAGAATTATTAGATGAGCTAAAATATGAGTTTCTAA
>NM_058241.3
GTGAATGAAGGAGCGGGCGGAGGAGGAAGTGTCATGGCGTCGGGCCGTGGAGCTTCTTCTCGCTGGTTCTTTACTCGGGAACAGCTGGAGAACACGCCGAGCCGCCGCTGCGGAGTGGAGGCGGATAAAGAGCTCTCGTGCCGCCAGCAGGCGGCCAACCTCATCCAGGAGATGGGACAGCGTCTCAATGTCTCTCAGCTTACAATAAACACTGCGATTGTTTATATGCACAGGTTTTATATGCACCATTCTTTCACCAAATTCAACAAAAATATAATATCGTCTACTGCATTATTTTTGGCTGCAAAAGTGGAAGAACAGGCTCGAAAACTTGAACATGTTATCAAAGTAGCACATGCTTGTCTTCATCCTCTAGAGCCACTGCTGGATACTAAATGTGATGCTTACCTTCAACAGACTCAAGAACTGGTTATACTTGAAACCATAATGCTACAAACTCTAGGTTTTGAGATCACCATTGAACACCCACACACAGATGTGGTGAAATGTACCCAGTTAGTAAGAGCAAGCAAGGATTTGGCACAGACATCCTATTTCATGGCTACCAACAGTCTGCATCTTACAACCTTCTGTCTTCAGTACAAACCAACAGTGATAGCATGTGTATGCATTCATTTGGCTTGCAAATGGTCCAATTGGGAGATCCCTGTATCAACTGATGGAAAGCATTGGTGGGAATATGTGGATCCTACAGTTACTCTAGAATTATTAGATGAGCTAACACATGAGTTTCTACAAATATTGGAGAAAACGCCTAATAGGTTGAAGAAGATTCGAAACTGGAGGGCTAATCAGGCAGCTAGGAAACCAAAAGTAGATGGACAGGTATCAGAGACACCACTTCTTGGTTCATCTTTGGTCCAGAATTCCATTTTAGTAGATAGTGTCACTGGTGTGCCTACAAACCCAAGTTTTCAGAAACCATCTACATCAGCATTCCCTGCGCCAGTACCTCTAAATTCAGGAAATATTTCTGTTCAAGACAGCCATACATCTGATAATTTGTCAATGCTAGCAACAGGAATGCCAAGTACTTCATACGGTTTATCATCACACCAGGAATGGCCTCAACATCAAGACTCAGCAAGGACAGAACAGCTATATTCACAGAAACAGGAGACATCTTTGTCTGGTAGCCAGTACAACATCAACTTCCAGCAGGGACCTTCTATATCACTGCATTCAGGATTACATCACAGACCTGACAAAATTTCAGATCATTCTTCTGTTAAGCAAGAATATACTCATAAAGCAGGGAGCAGTAAACACCATGGGCCAATTTCCACTACTCCAGGAATAATTCCTCAGAAAATGTCTTTAGATAAATATAGAGAAAAGCGTAAACTAGAAACTCTTGATCTCGATGTAAGGGATCATTATATAGCTGCCCAGGTAGAACAGCAGCACAAACAAGGGCAGTCACAGGCAGCCAGCAGCAGTTCTGTTACTTCTCCCATTAAAATGAAAATACCTATCGCAAATACTGAAAAATACATGGCAGACAAAAAGGAAAAGAGTGGGTCACTGAAATTACGGATTCCAATACCACCCACTGATAAAAGCGCCAGTAAAGAAGAACTGAAAATGAAAATAAAAGTTTCTTCTTCAGAAAGACACAGCTCTTCTGATGAAGGCAGTGGGAAGAGCAAACATTCAAGCCCACATATTAGCAGAGACCATAAGGAGAAGCACAAGGAGCATCCTTCAAGCCGCCACCACACCAGCAGCCACAAGCATTCCCACTCGCATAGTGGCAGCAGCAGCGGTGGCAGTAAACACAGTGCCGACGGAATACCACCCACTGTTCTGAGGAGTCCTGTTGGCCTGAGCAGTGATGGCATTTCCTCTAGCTCCAGCTCTTCAAGGAAGAGGCTGCATGTCAATGATGCATCTCACAACCACCACTCCAAAATGAGCAAAAGTTCCAAAAGTTCAGGTAGTTCATCTAGTTCTTCCTCCTCTGTTAAGCAGTATATATCCTCTCACAACTCTGTTTTTAACCATCCCTTACCCCCTCCTCCCCCTGTCACATACCAGGTGGGCTACGGACATCTCAGCACCCTCGTGAAACTGGACAAGAAGCCAGTGGAGACCAACGGTCCTGATGCCAATCACGAGTACAGTACAAGCAGCCAGCATATGGACTACAAAGACACATTCGACATGCTGGACTCACTGTTAAGTGCCCAAGGAATGAACATGTAATAATTTGTTTAGGTCAATTTTTCCTTTACTTTTTTAATTTAAAAATTGTTAGAATGGAAAAATTCCTTCTGATCTAGCAGTGGTAACCCCTGCTGTTGCTGCCACTGCTTCAATATTTGTAAGTGCTGCTTTATTCTTCATTCTGAAAAGAAGAGATTATAGTAAACAAGTCTTTATCTCCACATATGATAGTGTTATAAATACTGTAAAAGCATGGAAGGTGCAAAACTCAGTATTTCTACAATTGCAGCTAAGAACATTAGGATGAATGGCTGGCTGCTTCTAGGAATATAAGATGCCTCAAGCATTCATTATTTATGATTTGAATACTGTAGCTATTTTTTGTTGCTTGGCTTTTGAATGAGTGTAAATTGTTTTCTTTTGTGTATTTATACTTGTATGTATGATTTGCATGTTTCAATGATAAAGGGATAAAACAGTATACTGACAACTGTTTACAAGAAAGTGGAGAAAAATGTACATACATTTTTGTATGTTTAGATATTACCGTAAATACTCAGGATTGGAGCTGCTTGTAAGTATAACAATATACAGAATAACTTTATTTTATCTTGTCAGAGTCCATCACTAATCTAAAACAAAGGTGGCACTTTTTTATGTTAACCTTAAACTCTAGGCCTTACTGGAAGCCACTGATAGGGGACACTTCACTACCAGATGTGTGCAGTGCAACAGATGGTCATATACACTGTGAGGCACTGAAATTTTGCCTTCAGAGGTTCTGACCAGATTGGCTGCTGAAATAGCCCCTAACTTTCTGAAGGCTTGAAGAGGAAAAAATAAAGTTTACATACTCTTGATGTGAAGTGCATTTAAATGTTTGTTGGCTTGTTGCAGTTCTATGAAACAGAGCTGTTAATAATGGTTATGTGGATTACTGTGATTTGAAAACTAAATTCACAATAACTTACCTAGTAGAGATTTAGTGAGTTGTTTCCTTTAAAGAATTTTACACTACATATTTTAATAGTAAACAGGGATCACTTTTCCTTTAGCATTCAGAATGACACCATATTCTTAAATATACTCCTTCCCTGAAGCGTGTTTGTGTGTGATGCCATATTTCTTTTTCAGGTAAATGTAGTCTTCCTTATAAAAATGAAATTAAACCTATGCTCTCAATTCTTTTATATTCTAACAATAAATAAAAAAGAAAAGATTACTGACTGTGCATTGTACCTGTATTTATAGTTTATGGTTATCAGGAAGCTCTGTAAGAAAGAAAAGGTCAGCCTCCCAGGCAAACCAGTAGTGGAGGTTTTACATTTGTTTGCACATCTCAGTATATTTCTGTTGAGGTAAAGTTTGCACAGTCATCTGACTTCTGATCAAGCATTAGATTTTAACTTGTTTAGATTTTGTCTTAAACACCAGTAATATGGCTCTTGTTTATCAGCTAATCTTGAATTTATTCTGTGGTAAATCTTTTGAGTTGTTGAGTATATTTGAGATTGATTGGATTCGACCTCTTGTTGAACTGAAAACTTAATTTTTTCTCTGTATTTTTGTTACAAAGCCACTGATACGTGCACAATTGTAATTAAGTATGTTGCAGTTGTAAATATTAGAGTTTAATCTCATGCTCTACCTTTATTTAGCAATTACCTAATTTGCCAGTAGCTTTATAATTTTTAAAGATAATTGTTCATTATTTTGTCAATGTTATTTGAACTTGGGGTACTTAGGAGCCTCTTTGTAGGGACTGTGCCTAGGTAGCATGTCCTAACATTTGTTCTGGTCTTGCATAACTTCAGTAATCTTTGTCATTATATGTAACTTTGTTGCTCTGTATGGCATAATATTGTATCCATAAACATGGTAATTTTGATACAGTTATACTTTTACAGTGGTACATAATCCAAGGACTAGTATAGAATTAAGCTGAGTGCAAGATGAGGGAGGGAAGGGCTTTCTTGGTAATTTAGATGTGAAACCTCTACAGAGCTATCATGTAAAAACTACATAAGGTGGTTGTGCTACTGTATAATTGGGGGTGATAATACCAGGAATTTTAATAAGATTTTGTAAAGAATATCCAGAAAAGTAGTGAACTTATTTTCAGTAGACATAGAAAACAATGTGAATATTTAAGGTCTGTGACTATAGTTAAACTTCACTAAGAATTTGCAGAATTGTTTTGAGATGTGTGAATAAAGGTAATTTTATTGAATCTTCATTGGTGCTAATGATGGACAGTTAAAAAGATAGCTAGTGTATATTGTTATGGGTCAGTACTTATTAGTACTTCCAAAATTGAATTTGAAATGCTATGTATTCACTTTTCACTCTGTAAATGTAATTCTTTACAATGACTTTATTTATTAAAGGGCAGCCAGTTGTCATTTTTACAGGATTGTGTGAGCTATTCAAACTCTTCAACCCCTGAACAGGGTATTAAGCTTCCAAAATAATGATGGGGATAAATATGGAAATCCTTTTTAAGTTGTATTTCCATTAAACAAAAACCCTTATAATTCATACTATCATGAATTTGCTTTATCCATCTCATTTGCATAACAGTTCATCTGTCTGGTCCCATTAGGCTCTACCAAAGAAAGACTCTGATGAGTGGACATTATTACTGTGACTCTTGTAAGTAGCCATAAATAAACCAAAATAGTATCAAATTTAGGTATGAAATTCCACATGTGCAAAGTACTGTTAAGGTGATAACATTTTTGATGAGATTTAAAAAAATATTTGAAATATTAAAAAGCATTATCTTTAAACATCCTATAAAAGAGTGAGTCATTTTTAAGTTGTGTTTTCCCTAGATCACTGATTTGTTACCTTTACACAGAAGCACATTGCAAAGAAAGGCTTTATTTCTACCTCTTCCATTCAGTTTTCCAATATTGAGCTGTGTCCCTCTGAATATTTGCCTTAGCTATTTCAAAATAGGTATTTTCAGAACCAAAGCAAAGGGTGGTTTGTTCACTGAAACATTCTTAGAGGCCTACTTAACGGGCGGCAGTATCCGGTAGTGGTAAAACCTCACAGTTTCCTAATTGCAGGTATGTAAATACCAAAAAAGTCCTGTTGTCAGCCCTAGGTTTATCTTTGAAAGCAGTTAAATGTGCACCTTGGTCTTCCTCCGTGTGTTCAGATTCCTTCTGGTTAAAGTTCTTATTCAGAGTCATCTAAAAGAAATTTCTAACATGATGTATGGTTTCTTGAATGTCATGAGTGGCTGCGTATATTGCTTTGTAGCAACAGATTGTATTAATAATTAATAGAATACCTAATTTTTTTGGCCTATCCTCTTTGAACTAGAAATGACTACTTGAGGGCTATTTCAGAGAACCAATATGAAATGTTTTTGTTAGTACAAAATACCATTGCCTTAAAAGGTTTCAAGCACATTTTCTTTTCTATTTGAGAACTTAAATTGCTGACTTGTATTCGTTAAGCAACCTTAGAAATAAACCACTGCTTATATCTGCATGAATATTATGCATTTCATGAGTACAGTTAGTTGATTAGATATTTCAGGGTTTTGCATTTTCTATAGACATGGGGACTTTTTTAACATGGTAACGTCTTAGGAAAACCATTCTCTCAAGGTATTACACCATTTCCAATTTTATCCAAATGAAAAGCATATCTGCTTAAATTTAGGATGTCTTTGCTGAGAATATTTGGAGGCTCTTGTTAGGAAGAATCATGGATTCAGTATTTCTAACCTGATTACTGCCTCAGAGGCTGTCTTGAAGGGAGACAGTAGGATTCACTGACTACCTTTACCCAGATGAGGGATCAACAAATCTCACACTTAAACTAAATGAGTTGACAGGACAATAGGTGCTAATCTCATGTGCCCTAAGATGGACTTATTTAGATAGGGATTTTTGCATTGGAAAAGCAGCACATTCTCTGACCTTGGGTACCAAGCTATGATACTAATTTGAGAATCACATTCTGATACGTTAATATCAGAAATCAGTGAGCAACCTAATTGctgtaagctgacatacatggaagccgaaatcaaaaggttgcttTTGTTAGTTTCCCTGGAGCATCTATTTTTGTAATACATTTTGCCAGTGGGACTGAAAAGCTCAAAATGTTTTAGACCTAATATCATACATTAATTTTCTGCTCTGCAGTGTCAATTTGGGCACAGCCAGTTTTTACCTCTGTGGCACCTTCTTTATAATTTACTGTTACCTATTCTGCCTGACAGATTGATTAAGTAGGTTGATAAGATCCATCGAAGATTGAATGGCTAGGAGTAATTCTGTTCTCGTATAGGCAACTTAACTTCACTGTGGAATCCATTTATCTCAAAGTTTGAGGGCTGTCTACTTTATTTTCAAGTTTGGGGCGGAAACTCAAAATCCCGAGCATTGCCACTTTAGTAGTTTGTTTGATTTGCCTATTGTTTAATAATGAGTACATTCTTATTAAGTGATGAGTACATTCTTAATTTTAAGGTATGTTTTTTTCAAGCAGCTTCATTTTATTAGGAAAAATACATACTCATTTGTTGTAAACAGTGATTGTGGGGTTTCATTTTCTGAATGTACTCAAAACTCCCAACAACAATTGAACAGGATGTTTGCTAATAGAAAATCTAAAACAGGAATATGTGTATATGGCATGAATTAGTCATTGACTTTAAGCTTCTTATCCATACAAGGAACTAATAAAATGTTTATTGACAACATAAA

Publications

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