Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name PRR13P3
Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr11:117335659-117336683  UCSC
Coordinates (T2T) chr11:117352313-117353337  UCSC
Coordinates (hg19) chr11:117206375-117207399  UCSC
Strand -
Parental Sequence NM_018457.4
Parental seq. overlap 429 bp
Parental seq. overlap (%) 26.6%
Genomic Region Intergenic
Retrocopy Summary PRR13P3, located on chr11:117335659-117336683, is a retrocopy of the parental gene PRR13. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name PRR13
Full Name proline rich 13
Also known as TXR1
Coordinate chr12:53441734-53446638
Strand +
Gene summary Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes PRR13P4
Bonobo Pan paniscus PRR13P4
Gorilla Gorilla gorilla PRR13P3
Orangutan Pongo abelii PRR13P3
Gibbon Nomascus leucogenys PRR13P3
Green monkey Chlorocebus sabaeus PRR13P1
Crab-eating macaque Macaca fascicularis PRR13P5
Rhesus Macaca mulatta PRR13P5
Baboon Papio anubis PRR13P6
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>PRR13P3
TGCTGTTGAGCCCTGAATGGATAGGGAAAATGGGAAGAGGATTGCCATGGCCTGGCCATCTTCTTGCTGCTTGGATAGATCAGATAGCTAATGAGTTTAGCAGGGGAGCTATTTTTTTGAAGATGATGAACTAAATATTGAAGACAAGTTTGAGATCTGTAAAATGTGATTTTTTTTTACTTCTGCTTATAATACTTGTGATTGGGGAGGTTTGTGGAAATTTAATTATGATTAGAAACCTCTATCTTTTTTGTAATGTTGGCATACTTGGGGAATTTAGTGGCAAATACATTCCCCAGCAGGCCTTTTGTTGGTTGCACTAACTGCAAGTTTGGTGGGAAGTAGAGTCCGTTTAGTCGATGAGCTTTGACCGCCGTTTTGGAACCTTACCTCTCCTCCTTAGCCCAATATAAGCAGCGATTCTGACTGAATACAGGCCCTGGACCCTTCCCTCAAGTCTCACCAGTTCTGCTCTCCCATCAAGCTTCAGAAGCCATGTTGTACTGGGGGAAAGTAGCCCTTGTGCTCAGAACGCATCAAGCCCAGGCAGCCGTGGAAAGGCTGGAGGACACACCTAAACATGTGGAATCCCAATGCCAGACAGCCAGGGCCAAATCCATATCCCCCAACACTGGGTGCCCTGGAGGTTCCAATCCTGCCCACCCACCACCTATCAATCCACCCTTTCCCCCAGGCCCCTGTCCTCCTCCCCTAGGAGTTCCCCAGGGCAATCCAGCTTTCCTCCCAGGTGGGGCCCCTCATCCTGTACCACAGCCAGGGTATCCAGGATGCCAATCCTCGGGTCCCCACCTTCCTCCATACCCACCGCCTGCCCCTGGAATCCCTCCTGTGAATCTCTTGGCTCCTGGCATGGTCAGACCAGCAGTGACAGCGGACAAGAAGATGCAGAATAAAATGAAGAAAGCTCATAAAAAGATGCACAAGCACCAAAAGCATGGCAAGCATt
>NM_018457.4
GACTAGGAAGAGCCGAGACTGCGAAGGAGAACGCAGCAAGCCCAGGCGGCGGTGGAAAGGCTGGAGGACACACCTAAACATGTGGAATCCCAATGCCGGGCAGCCAGGGCCAAATCCATATCCCCCCAATATTGGGTGCCCTGGAGGTTCCAATCCTGCCCACCCACCACCTATTAATCCACCCTTTCCCCCAGGCCCCTGTCCTCCTCCCCCAGGAGCTCCCCATGGCAATCCAGCTTTCCCCCCAGGTGGGCCCCCTCATCCTGTGCCACAGCCAGGGTATCCAGGATGCCAACCGTTGGGTCCCTACCCTCCTCCATACCCACCGCCTGCCCCTGGAATCCCTCCTGTGAATCCCTTGGCTCCTGGCATGGTTGGACCAGCAGTGATAGTAGACAAGAAGATGCAGAAGAAAATGAAGAAAGCTCATAAAAAGATGcacaagcaccaaaagcaccacaagtaccacaagcaTGGCAAGcattcctcctcttcctcctcctcttccagcagtgattctgactgAATACAGGCCCTGGACCCTTCCCTCAAGTCTCACCAGTTCTGCTCTCCCATCAAGCTTCAGATGCCATGTTGTACTGGGGGAATGTAGCCCTTGTGCTCCCCACCCCCTACCTCCACCTGAGCCTCACCCTGCTGTTGAGCCCTGAGTGGCTAGGGGAAATGGGAAGAGGATTGCCATGGCCTGGCCATCTTGTTGCTGCTTGGTTAGATCATATAGCTAATGAATTAGGCAGGGGAGCTATTTTTTGAAGATGATGAACTAAATGTTGAAGACAAGTTTGAGATCTGTAAAATGTGATTTTTTACTTCCACTTATAATACTTGTGATTGGGGAGGTTTGTGGAAATTCAATTATGATGAAAAACCTATCTTTTTTGTAATGTTGGCATACTTGGGGAATTTAGTGGCAAATACATTCCCCAGCAGGCCTTTTGTTGGTTGCACTAACTGCAAGGTTGCTGGGAAGTAGAGTCCATTTGGTTGATGAGCTTTGACTGCGGTTTTGGAACCTTACCTCTCCTCCTTAGCCCAATATGCTGTCTTGGGTCCTATTCAAATAAAGTTATTTCTCCTGGTCTCA

Publications

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