Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name AKR7A2P1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr1). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:112923562-112924497  UCSC
Coordinates (T2T) chr1:112936137-112937072  UCSC
Coordinates (hg19) chr1:113466184-113467119  UCSC
Strand +
Parental Sequence NM_012067.3
Parental seq. overlap 875 bp
Parental seq. overlap (%) 72%
Genomic Region Intragenic (SLC16A1)
Retrocopy Summary AKR7A2P1, located on chr1:112923562-112924497, is a retrocopy of the parental gene AKR7A3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name AKR7A3
Full Name aldo-keto reductase family 7 member A3
Also known as AFAR2
Coordinate chr1:19274229-19289362
Strand -
Gene summary Aldo-keto reductases, such as AKR7A3, are involved in the detoxification of aldehydes and ketones.[supplied by OMIM, Apr 2004]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes LOC742959P1
Bonobo Pan paniscus LOC100981286P1
Gorilla Gorilla gorilla LOC101150628P1
Orangutan Pongo abelii LOC100456086P1
Gibbon Nomascus leucogenys LOC105737551P1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>AKR7A2P1
CTGAAAATTGATACCAAGGCCAATCCATTGTTTGGGAACTCCCTGAAACCTGACAGTCTCCGGTTCCAGCTGGAGACGTCACTGAAGTGGCTGCAGTGTCCCCGAGTGGACCTCTTCTACCTGCTCAGGCCAGACCACAGCACCCCGGTGGAAGAGACACTGAGTGCCTGCCACCAGCTGCACCAGGAGGGCAAGTTCCTGGATCTTGGCCTCTCCAACTATGCCACCTGGGAAGTGGCCAAGATCTGTAACCTCTGCAAGAGCAATGGCTGGACCCTGCCCACTGTGTACCAGGGCATGTACAACGCCACCACCCAGCAGGTGAAAACGGAGCTCTTCCCCTGCCTCAGGCACTCTGGACTGAGGTTCTATGCCTTCAACCCTCTGGCTGGGGACCTGCTGACTGGCAAGTACAAGTATAAGGACAAGGACAGGAAACAGCCCATGGGCCGCTTCTTTGGGACTCAATGGGCAGAGATCTACAGGAATCGCTTCTGGAAGAAGCACCACTTCGATGGCATTGCCCTGGTAGAGAAGGCCCTGCAGGCCGCGTATGGCGCCAGCGCCCCCAGCATGACCTCGGCTGCCCTCTGGTGGATGTACCACCACTCACAGCTGCAGGGTGCCCACGGGGACGCAGTCATCCTGGGCATGTCCAGCTTGGAGCAGTTGGAGCAGAACTTGGCAGCGGCAGAGGAAGGGCCCCTGGAGCCAGATGTTGTGGAGGCCTTTAATCAAGCCTGGCAATTGGTTGCTCACGAATGTCCCAACTACTTCCACTAGGCCCATCGTTTCTCAGGTTGCCCAAGGCTCTTCTGTAACCTCTTTTGTTTCTCACACTTTCTTTAATTTAGAAGTGCCTCAGTAAATTCTTAGGGATGGAAGTATTTGGACAAAAACCTAACAGTAAAGTCACCACCAAATGAAGAATGAAAC
>NM_012067.3
CTGGTGCTTCCGACCGCTGCGCGCGGCTCCTGGGCTGTCACAGTCTCCCGTTGCCGCCGTCATGTCCCGGCAGCTGTCGCGGGCCCGGCCAGCCACGGTGCTGGGCGCCATGGAGATGGGGCGCCGCATGGACGCGCCCACCAGCGCCGCAGTCACGCGCGCCTTCCTGGAGCGCGGCCACACCGAGATAGACACGGCCTTCGTGTACAGCGAGGGCCAGTCCGAGACCATCCTTGGCGGCCTGGGGCTCCGGCTGGGCGGCAGCGACTGCAGAGTGAAAATTGATACCAAGGCCATTCCACTGTTTGGGAACTCCCTGAAGCCTGACAGTCTCCGGTTCCAGCTGGAGACGTCACTGAAGCGGCTGCAGTGTCCCCGAGTGGACCTCTTCTACCTGCATATGCCAGACCACAGCACCCCGGTGGAAGAGACACTGCGTGCCTGCCACCAGCTGCACCAGGAGGGCAAGTTCGTGGAGCTTGGCCTCTCCAACTATGCAGCCTGGGAAGTGGCCGAGATCTGTACCCTCTGCAAGAGCAACGGCTGGATCCTGCCCACTGTGTACCAGGGCATGTACAATGCCATCACCCGGCAGGTGGAAACGGAGCTCTTCCCCTGCCTCAGGCACTTTGGACTGAGGTTCTATGCCTTCAACCCTCTGGCTGGGGGCCTGCTGACCGGCAAGTACAAGTATGAGGACAAGAATGGGAAACAGCCCGTGGGCCGCTTCTTTGGGAATACCTGGGCAGAGATGTACAGGAATCGCTACTGGAAGGAGCACCACTTTGAGGGCATTGCCCTGGTGGAGAAGGCCCTGCAGGCCGCGTATGGCGCCAGCGCCCCCAGCATGACCTCGGCCACCCTCCGGTGGATGTACCACCACTCACAGCTGCAGGGTGCCCACGGGGACGCGGTCATCCTGGGCATGTCCAGCCTGGAGCAGCTGGAGCAGAACTTGGCAGCGGCAGAGGAAGGGCCCCTGGAGCCGGCTGTCGTGGACGCCTTTAATCAAGCCTGGCATTTGGTTACTCACGAATGTCCCAACTACTTCCGCTAGGCCCATCGTTTCTCAGGCTGCCCAAGGCTCTTCTGTAACATCTTTTGTTACTCACATTTTCTTTAATTTAGAACTGCCTCAGTAAATTCTTAGGGATGGAAGTATTTGGACAAAAACCTAATAGAAGAGTCACCACCAAATGAAGAATAAAACTCCCA

Publications

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