Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name CENPUP1
Wait
Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chr4). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr11:13756056-13758341  UCSC
Coordinates (T2T) chr11:13848272-13850562  UCSC
Coordinates (hg19) chr11:13777603-13779888  UCSC
Strand +
Parental Sequence NM_024629.4
Parental seq. overlap 1705 bp
Parental seq. overlap (%) 66.5%
Genomic Region Intergenic
Retrocopy Summary CENPUP1, located on chr11:13756056-13758341, is a retrocopy of the parental gene CENPU. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name CENPU
Full Name centromere protein U
Also known as CENP50|CENPU50|KLIP1|MLF1IP|PBIP1
Coordinate chr4:184694085-184734096
Strand -
Gene summary The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes CENPUP1
Bonobo Pan paniscus CENPUP1
Orangutan Pongo abelii CENPUP1
Gorilla Gorilla gorilla Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

The Genotype-Tissue Expression project - (GTEx)

Related Sequence

>CENPUP1
ATTCAAAGAACACTTTAGAAAGAACACATTCCATGAAAAGTAAAGCTGCTCAAAAGTACATGTCTATTGATATGTTCAATTTTCCTGATAATTCTGATATCTCAAGCATTGGCAGTCTAGATGAAAATGAGAAAGATGAAGAACCTTAGGAAGGCTTTCATCCTCCTTTACACAACACAGCTATATATGCTGATGAAGAATTATTCTCCTGACATTGTGGATTATCTATCTCTTCAAATCCCCCAGGAAACAAAGCAAAAAGAAGTTCAGACACTTCTGAAAATAAAGCAAGTGAAAACAAATCTGCAAAAATTAGTGCAAAAaCAACAACAACAAAAAAAAACAGTGCAAAAAAAGCCAGGAAGAAAACACAAGCCCATTCATAATGACTGGGAAAGTACTGAAGAAAGTGATGTAAGAAGAAAAGCTAAATCAGCAGACAAAATGGGTACACAATGACACGAGGCTATTCCTCCAACTACAGCATCTTCAGAACTTTCAGAGAAACCAGCTGAGTTGATCACTTCTAAAAAGATAGGACCTCTTAGTGCCCAGCCCTCTGTTGATAAAGAGATCTTGGCAACAGAAATTTAATTGAAAACTCAGAAAAAAGGAAAGATGTCTTATGACAAAAGGAAGAAATCAAGAAGTAAAGCCATTGACTCAGATACTTCCAACATTGTGCATATTTGGTGTCTATAAGAAAACCAGTAACATCATGGAGTTGAATATTGTTTTGCCCACAGTTGAGAAAATCCTCCTAGAGTATAAACAAAGAATAGAATCTAAAATTTGTAAGAAAGCCATCAACACATTTTATTTTAACATTAAAAAGAACCCATCAAAAAGTTTAAAGAAGTCCAGATGTTGAAAAACTTGAAAAGGAAGAATGCTAAGATGATTTCAGATATTGAAAAGGCAACGTTTGATTGAAGTTTAGGATGAACTGCTTCCATTAGAGCCACAGCTGAAACAACTACAAACAAAATGTGATAAACTTAAGGAGAGAAAGTCTTCCCTTAGGAATGCAGCATATTTCTTATCTAATTTAAAATGGCTTTATCAAGATTATCAGATGTTCAGGAGAAAGAAGCAAACATAAAGGAAACGTATAATTCAACCAGCCTTCCAGCTCTGTTATCTTAACAATTTTGGGAGCTGAAAATCACCTGCAAAATATCAACCATCAATTAGAGAAGCTCCTTGACCAGAAAGAAGAAGCGCAGCCTACTAAAATGTGCCTATAGAAATGTTAGTTTCATGCTACTGTTACCTTCTGAAACTATACTTTTATAAATAATTTTTTTTGCAAAGAAGTATGGCCTAGTTATCAGAACCTAATATTTGTCATTCAAATTAAATGACTGTGAACAATGTTAAATGGCATCCGTTTTTCAAATAGTTTTAAAGGCCATGATCATCTTTTCTGGCTAATATCTTGAGTAATAAATTTTAAACTGTTGACATCATATCTTAATCAGCCCCAGATACAAGAGTTTTAATAAACATAAAATTATCTTGATGTGAACATAAACTAATTTTGATTAAGAAGGAGATTTCTACTGAATTTAAGTACACCAAAGCTAATTTTCGGTAAAACTGGTTTATAGAAGTAAAAAACAAAAATTGGAAAACAAAGTGATAAAACTTAGTTTATGTAAACAGGTTTAATGACAATATATTTGTTATCAAATCTCACAGACATCAGGCAAATTATAGCCTGGTGACATAAGTGTCCATAGTGAATTAGGTACTTGTATAGTACTTCCGTGATTAGTTTATCAGGAATTTCATCCATTTCACTGTTATAACTGAGAAGACTGTTCTCTGCAGCTTCAGCTAATTCGACATCTTCAGTAGCTTCTAAAATATAAGCATCTTCAATGCCATTATCCCAGTCAGTGTCAGCAGAAGCATCTGTTGACACCTTACTAGTTGATGGTTTATGAGGATTCTGGGTTTCATTGCTCTTAATTTCATCTGCTTCA
>NM_024629.4
AGCTTCCAGTCGCTCGAGAGCGGAGAGCGGCACCATGGCCCCgcgggggcggcggcggccgcggcCTCACAGGTCTGAGGGCGCAAGACGTTCAAAGAACACTTTAGAAAGAACACATTCCATGAAAGATAAAGCTGGTCAAAAGTGCAAGCCTATTGACGTGTTCGACTTTCCTGATAATTCTGATGTCTCAAGCATTGGCAGGCTGGGTGAAAATGAGAAAGATGAAGAAACTTATGAGACCTTTGATCCTCCTTTACATAGCACAGCTATATATGCTGATGAAGAAGAATTCTCCAAACATTGTGGACTGTCTCTCTCTTCAACTCCTCCAGGAAAAGAAGCAAAAAGAAGTTCAGACACTTCTGGAAATGAAGCAAGTGAAATCGAATCTGTAAAAATTAGTGCAAAAAAGCCAGGAAGAAAGCTCAGGCCCATTAGTGATGACTCTGAAAGCATTGAAGAAAGTGATACAAGGAGAAAAGTTAAATCAGCAGAGAAAATAAGTACACAACGTCATGAGGTTATTCGAACCACAGCGTCTTCAGAACTTTCAGAGAAACCAGCTGAGTCTGTCACTTCTAAAAAGACAGGACCCCTTAGTGCCCAGCCCTCTGTTGAAAAAGAGAACTTGGCAATAGAAAGTCAATCGAAAACTCAGAAAAAAGGGAAGATATCTCATGACAAAAGGAAGAAATCAAGAAGTAAAGCCATAGGCTCAGATACTTCTGACATTGTGCACATTTGGTGTCCAGAAGGAATGAAAACCAGTGACATCAAGGAGTTGAATATTGTTTTGCCTGAATTTGAGAAAACCCACCTAGAGCATCAACAAAGAATAGAATCTAAAGTTTGTAAGGCAGCCATCGCCACATTTTATGTTAATGTTAAAGAACAATTCATCAAAATGCTTAAAGAAAGCCAGATGTTGACAAATCTGAAAAGGAAGAATGCTAAGATGATTTCAGATATCGAAAAGAAAAGGCAGCGTATGATTGAAGTCCAGGATGAACTGCTTCGGTTAGAGCCACAGCTGAAACAACTACAAACAAAATATGATGAACTTAAAGAGAGAAAGTCTTCCCTTAGGAATGCAGCATATTTCTTATCTAATTTAAAACAGCTTTATCAAGATTATTCAGATGTTCAAGCTCAAGAACCAAACGTAAAGGAAACGTATGATTCATCCAGCCTTCCAGCTCTGTTATTTAAAGCAAGAACACTTCTGGGAGCCGAAAGCCATCTGCGAAATATCAACCATCAGTTAGAGAAGCTCCTTGACCAGGGATGAGAAGAGCAGTCTACTAAAATGTGCCTATAGGAAGACTAGTCTCATGCTGTTACCTTCTGAAACTGTACCTTTATAAATCAATTGTTTTGCAAAGAAGTTATGGCCTACTTAGAATCTAAAATTTGTTATTCAAATTAAATGGCTGTGAACAATGTTAAATAGCATCAGTTTGTCCAATAGTTTTAAAGGCCATAATCATCTTTTCTGGTTAATATCTTGAGTAATTTTAAAATGTTGACACCTTAATCGGTCCCAGGTATGAGCTATAATAAACTTGTAAAATTAAGTTGATGTGAACATAATTTTGATTAATTAATAAGGCGATTTCTCCTGAATTTACACCAAAGCTAATTTTTAATGAAATTGGTTTACAGAAGTAAAAAACAAAAATTGGAAAGCAAAGTAATAAAACTTAGTTTATATAAACAGGTTGAATGATATATTTATCAAATCTCACAGACATCAGGCAAATTATAGCCTGGTGACAAAAGTGTTCATAGTGAATTAGTTACTCTTGTAATACTTCTATAATTAGTTCATCAGGAATTTCATCCACTTCACTGTTATAACTGAGAAGACTGTTCTCTGCAGCTTCAGCTAATTCAGCATCTTCAGTAGCTTCTAAAAAATAAGCATCATCAATGCCATTATCCCAGACAGCATCAGCAGATGCACCTGTTGACAGCCTGCTAGGTGATGGTTTATGAGGATTCTGGGTTTCATTGCTCCTAGTTTCATCTGCTTCATCTGTTGTAAACTCTTCTTCCTTTATTTCAGTGGTGAAGGGATAGAGAGTGGGATAGGAAAATATTTACTCAGGATATGTGATTTAACCTTATACTCTATGTTGAAGTAAGGTATTAAGTGACAGATACTAAAGTGAATATGCAGGAGGAATGCTGTCTCCGATATCtcaccgtgggaatgagtgcactgattcaaacgttgctgcactgaagctcagacacacttgaaactccaaatttgaaattacctacagttctgtgcacatacttttcaatactccccgacggaagagcaagggtggatttaatttttTAACAAGTGGACAGTCCAGCTGAAGACAAATCAGAAGATAAATTTGCTATCTTGACAATGGACTTAGTACCCATGCTTTAAATTTTAAAGTATTTAGCAAATCGTAAACATGGATTGAAAAAAGATTAAAAACAGTTGCCAAAA

Publications

PMID - Link Title
No publications available for this retrocopy