Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name NAP1L4P1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:116531760-116534389  UCSC
Coordinates (T2T) chr1:116542185-116544814  UCSC
Coordinates (hg19) chr1:117074382-117077011  UCSC
Strand -
Parental Sequence NM_001369385.1
Parental seq. overlap 1473 bp
Parental seq. overlap (%) 38.9%
Genomic Region Intragenic (CD58)
Retrocopy Summary NAP1L4P1, located on chr1:116531760-116534389, is a retrocopy of the parental gene NAP1L4. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name NAP1L4
Full Name nucleosome assembly protein 1 like 4
Also known as NAP1L4b|NAP2|NAP2L|hNAP2
Coordinate chr11:2944437-2992329
Strand -
Gene summary This gene encodes a member of the nucleosome assembly protein (NAP) family which can interact with both core and linker histones. It can shuttle between the cytoplasm and nucleus, suggesting a role as a histone chaperone. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes NAP1L4P1
Bonobo Pan paniscus NAP1L4P1
Gorilla Gorilla gorilla NAP1L4P1
Orangutan Pongo abelii NAP1L4P1
Gibbon Nomascus leucogenys NAP1L4P1
Green monkey Chlorocebus sabaeus NAP1L4P1
Crab-eating macaque Macaca fascicularis NAP1L4P1
Rhesus Macaca mulatta NAP1L4P1
Baboon Papio anubis NAP1L4P1
Golden snub-nosed monkey Rhinopithecus roxellana NAP1L4P1
Marmoset Callithrix jacchus NAP1L4P2
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>NAP1L4P1
GCTTAATGTGTACAGTGGCAACTGAAATGCATTTCAGAAATAGGAGGTTTTGTCCAATACCCTCTGCAGCCTTGGTGCCTGTAGCTCTGGACTTGCCTGGACCCTTCCCTGCGGGAGGGCCCCATAGACCCCATTGGGGTGGGGTGGGATGGGGTGGGGATCACTTGGCTAAAAGGGCCGAGGTCTGGTGATGAGGTTCCAGGGATCTAGAACCTCTCCTACCACTCCTGCAGTTGGACTGAATTCTTTCCTTTCATTTGAAGAAACCCACTCGCTGTTTTCAGCTGCTTAATCTGCTGAGTGTGCAGCCTGCATCACCTGCTGTATGCTAATCATCTCAGAAGGGCCGTGTAGAGTAGGGCCGTATTCTCCTTAGGATGTTGCTTTTTGATCTTCTTTTTTAAGGGTTGGGTCAGGGTTGTGGCACACCAGCTCAGGCGAGAGCTGCCACGGGTCACCTCATATTTATTTATCCCTTCTTGCCTGTGAGGACTGCGGCCTTTTGCTGTCGCTCGTCCTTGCCATTTCTGAACCACCCTGGTGACCTGAGCAGGAAGATGTGCCACTTCCTAGCAGGAGCAAGGGCTGTGCGGAAGAAACACTGCTTCCTGCCACCAGGGCTGAAGACGCGAGCCTGTCCTCGTGACACAGGCACCGCCCTGCTGCCGGAGTTGGGATTCGGCAGTGTTCTCCAGTGAGGGGCTGGGCTGGGAAGTCCTGCGTTTCATTTGAGCATATGAGCGTCAAGTCCTGCTTTCTCAGTAGTCCCATTGCTGGGCCCCACCATTCATCCTGTCTGAAGGTCCTGGTTGGTGTGACCGGTTGGTGGCTGGTGAGTGGGGTTTCCAAGTGGGTGACAGCGCTCTGTGGCAGCCGGGGATGGCCTTGTCCGCGCTGACCAGGCCTGTAGAGAGTGCTCAGCCTAACCTTAGAACACATTTATAACTGAATACAGTGTTTTCAATTTGTACATAATAGTTAGAATATTCTATTAAAGTTATGAAACACGGAGACGTCCAGGACCTCTTTATTAGATGTTTAGGAATTTGAGTTTTTCCGTAGGGCGATGGTCATCGTGAGCATCTGTGGGGTCAGGCTGGGCTAACTGGGGTTTTGATTGTAAGTTTCGTGTGGACGAGGGCATGTCTGATGGGGAAGAAAGTCCTTGGCATTGCATCTCAGCTGTTGGGAGCTGTGCGGTGCGAGCCAGATGGGCGGCGTGTGCTCCCCGAGGACTGGCCTGAGTGCCTTAGCCTAGTTACTCACGGGACTTGGTTTACCAGACAAGGGGATAAAAACATTCAGATGGCAGATAACAGTTTTTCAGATGGGGTTCCTTCAGATTTCGTGGAAGCTGCTAAAAATGCAAGTAAGACGGAAAAGCTCACGGATCAGGTGATGCAGAATCCTGGAGTTTTGGCAGCTTTACAGGAGCGACTTGACAATGCCCCTCACACCCCTTCCAGCTACATCGAAACTTTACCTAAAGCAGTAAAAAGAAGAATTAATGCATTGAAACAAATTCAGGTGAGATGCGCTCATATAGAAGCCAAGTTCTATGAAGAAGTTCATGACTTGGAAAGAAAATATGCAGCATTATACCAGCCTCTCTTTGACGAGAGAAGAGAATTTATCACCGGTGATGTTGAACCAACATCTGATATGGAATCAGAATGGCACCGTGAAAATGAAGAGGAGGAGAAATTGGCTGGAGACAGGAAAAATAAAGTAGTCATAACAGAAAAAGCAGCAGCAACAGCTGAAGAGCCAAATCCCAAAGGAATTCCAGAGTTCTGGTTTACCATCTTTAGAAATGTAGATATGCTAAGTGAATTAGTCCAGGAATATGATGAACCAATCTTGAAATACCTGCAGGATATTAAAGTGAAGTTTTCTGACCCTGGACAGCCTATGTCTTTCATATTAAGAGTTCCACTTTCAACCCAATGACTGCTTTGCCAACTCAGTCCTGACAAAAACCTGCAAGATGAAATCAGAACCAGATAAGGCTGATCCCTTTTCATTTGCAGGTCCTGAGATCATGGACTGCGATGGGTGTACTATTGACTGGAAGAAAGGAAAGAATGTTACTGTCAAAACCATCAAGAAAAAGCAGAAGCGTAAGGGTCCAGGCACTGTTAGAACAATTACCAAACAAGTATCCAATGAGTCATTTTTCAACTTCTTCAATCCACTGAAAGCATCTGGGGACGGAGAATCACTGGATAAAGATTCTGAATTCGTATTAGCCTCTGATTTTGAAATTGGACACTTTTTCCGTGAGCGGACCACAGGCTGTGCTGTACTTCGCTGGGGAGGCCTTAAAGGATGATGACAATTTTGACGAAGGTGAAGAAGAAGAGGACGAATTAGAAGGTGATGAGGAGGGAGAAGATGAGGATGAGGTGGAAATTAATCCCAACAAGGAACCCAGCCAGCCGGCGGAATGCAAGCAGCAGTAGGAAGTGGAGGTGGGCGCCTGGCAGACCGGCTGTCGCGACTCCGGGCCTGTAGCGGGAGGCCTCAGTCTTTGCCGCATGCGGCACAATCCCGTCGACAGCGCTTACTCCATCTAATCGTTTTCAAGTGCATGAt
>NM_001369385.1
GGAGACGTCCAGGACTTCTTTATTAGATGTTTAGGAATTTGAGTTTTTCCGTAGGGCGGTTGTCATCGTGAGCCTCTGTGGGGTCAGGCTGGGCTAACTGGGGTTTTGATGTCAGTTTGGTGTGGCCGAGGGCATGTCTGACGGGGAAGAAAGTCCTTGGCGTTGCTTCTTAGCTGTTGGGAGCTGTGCGGTGGGAGCGAGCTGGGCGGCGTGCGCTCCCCGAGGACTGGCCTGAGTGGCCTTAGACTAGTTACTCACGGGACTTGGTTTCCCAGCCAAGGGAAAAGTGTTTTAGGCTTCCAGAGTAGAAATCTGATATTACTTCGTTTGATTCTTCGACCACTATGGTGATAGGAAGTAGCTGATCTCTGCAGGAAACTGCTGTTACCTGACCTCAGCTGAATTTTTGTGGGACCTCCTGAGGGGATAAAAACATTCAGATGGCAGATCACAGTTTTTCAGATGGGGTTCCTTCAGATTCCGTGGAAGCTGCTAAAAATGCAAGTAACACAGAAAAGCTCACAGATCAGGTGATGCAGAATCCTCGAGTTCTGGCAGCTTTACAGGAGCGACTTGACAATGTCCCTCACACCCCTTCCAGCTACATCGAAACTTTACCTAAAGCAGTAAAAAGAAGAATTAATGCATTGAAACAACTTCAGGTGAGATGTGCTCACATAGAAGCCAAGTTCTATGAAGAGGTACATGACTTGGAAAGAAAGTATGCAGCGCTATACCAGCCTCTCTTTGACAAGAGAAGAGAATTTATCACCGGCGATGTTGAACCAACAGATGCGGAATCGGAATGGCACAGTGAAAATGAAGAGGAAGAGAAATTGGCTGGAGACATGAAAAGTAAAGTAGTCGTCACAGAAAAAGCAGCGGCAACGGCTGAAGAGCCAGATCCCAAAGGAATTCCAGAGTTCTGGTTTACCATCTTCAGAAATGTGGACATGCTGAGTGAATTAGTCCAGGAATATGATGAACCAATCTTGAAACACCTGCAGGATATTAAAGTGAAATTTTCTGACCCTGGACAGCCTATGTCTTTTGTGTTAGAGTTCCACTTTGAACCCAACGACTACTTTACCAACTCAGTCCTGACAAAAACCTACAAGATGAAATCAGAACCAGATAAGGCTGATCCCTTTTCCTTTGAAGGTCCTGAGATTGTGGACTGTGACGGGTGTACTATTGACTGGAAGAAAGGAAAGAATGTTACTGTCAAAACCATCAAGAAAAAGCAGAAGCATAAGGGTCGAGGCACTGTTAGAACAATTACGAAACAAGTACCCAATGAGTCCTTTTTCAACTTCTTCAATCCATTGAAAGCATCCGGGGATGGAGAATCACTGGATGAAGATTCTGAATTCACATTAGCCTCTGATTTTGAAATTGGACACTTTTTCCGTGAGCGGATAGTCCCGCGGGCTGTGCTGTACTTCACTGGGGAGGCCATAGAAGATGATGACAATTTTgaagaaggtgaagaaggagaagaggagGAATTAGAAGGTGACGAGGAGGGAGAAGACGAGGATGATGCGGAAATTAACCCCAAGAAGGAACCCAGCCAGCCGGCGGAATGCAAGCAGCAGTAGGAAGCGGAGGCGGGTGCCTGGCAGACCGGCTGTCGGGACTCCAGGCCTGTGGGCGGGGCCTCGGTCCTTGCCGCAGCACAATCCCGTGGACAGAGCTTACTCCATCTAACTCGTTTTCAAGTGCATGAttttcactttcacttttcctttttccttattattttGCTTAACTTGTACAGTGGCAACTGAAATGCATTTCAGAAATAGGAGGTTTCGTCCAGCACCCTCTGCAGCCTTGGTGCCTGTAGCTCTGGACTTCCCTGGGCCTTTCCCTGTGGGAGGGCCCTGTAGACCACATCAGGGTGGGGTGGGGGTCACTTGGCAAAAAGGGCCGAGGTCTGGTGATGTGGTTCCCAGGATCTGGAACCTCTCCCACCCCTCCTGCAGTTGGACTGAATTCTTCCCTTTCATCCGAAGAAACCCACTTGCTGTTTCCAGCCGCTGAATCTGCTGAGTGTGCAGCCTGCATCACCTGCTGTATGCCGATCATCTCAGAAAGGGCTGTGTAGAGTAGGGCCCTGTTCTCCTTAGGATGTTGCTTCTTCATTTTTTTTTTTTTTTAGGGGTGGGTCAGGGTTGTGACACACCAGCCCAGGTGAGAGCTGCTGCGGGTCACCTCATATTTATTTATCCCTTCTTGCCTGTGAGGACTGCGGCTTTTCGCTGTGGCTCGTCCTTAACGTTTCTGAACCACCTTGGTGCCCTGAGCAGGAAGATGTGCCACTTCCTAGCAGGCGCAAGGCCTGTGCGGAAGAAACGCCGCTCCCTGCCACCAGGGCTGAAGATGCGAGCCCGTCCTCATGACGCAGGCGCCACCCTGCTGCCGGAGCCGGGCTTCGGCAGTCTTCTCCACTGAGGGACTGGGCTGGGAAGTCCTGCGTTTCAGTGGAGCGTATGAGCGTCAAGTCCTGCTTTCTCAGTAGCCCCATTGCGGGGCCCCACCATTCATCCTGTCTGAAGGTCCTGGGTTTGGTGTGACCGCTTGGCGGCTGGTGGGTGGGGTTTTCAAGTGGGTGACGGCGCTCTCCGGCAGCCGGGGATGGCCGTGTCCGCACTGACCAGGCCTGTGGAGAGTGCTCGGCCTAACCTTAGAACACATTTGTAACTGAATACAGTGTTTTCAATTTGTACAGAATAGTTAGAATATTCTATTAAAGTGGTGAAACATTGA

Publications

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