Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name ST13P5
Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chr22). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr11:18261887-18263501  UCSC
Coordinates (T2T) chr11:18357414-18359028  UCSC
Coordinates (hg19) chr11:18283434-18285048  UCSC
Strand +
Parental Sequence NM_003932.5
Parental seq. overlap 1572 bp
Parental seq. overlap (%) 48.9%
Genomic Region Intergenic
Retrocopy Summary ST13P5, located on chr11:18261887-18263501, is a retrocopy of the parental gene ST13. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name ST13
Full Name ST13 Hsp70 interacting protein
Also known as AAG2|FAM10A1|FAM10A4|HIP|HOP|HSPABP|HSPABP1|P48|PRO0786|SNC6
Coordinate chr22:40824535-40856639
Strand -
Gene summary The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes ST13P16
Bonobo Pan paniscus ST13P16
Gorilla Gorilla gorilla ST13P14
Orangutan Pongo abelii ST13P16
Gibbon Nomascus leucogenys ST13P15
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>ST13P5
CGCGGCAGCCGCCCCCTTCTGCGCGGTCATGCCGAGCCAGCACCTGGGCCTGGAACTGGGCCGCAGCCCCCAGCTTCACCCACCACCTCCCTACCATGGACCCCTGCAAAGTGAACGAGCTTCGGGCCTTTGTGAAAATGTGTAAGCAGGATCCGAGCGTTCTGCACACCGAGGAAATGCGCTTCCTGAGAGAGTGGGTGGAGAGCATGGGAGGTAAAGTACCACCTGCTACTCAGAAGGCTAAATCAGAAGAAAATACCAAGGAAGAAAAACCTGATAGTAAGAAGGTGGAGGAAGACTTAAAGGCAGACGAACCATCAACTGAGGAAAGTGATCTAGAAATTGATAAAGAAGGTGTGATTGAACCAGACACTGATGCTCCTCAAGAAATGGGAGATGAAAATGTGGAGATAACGGAGGAGATGATGGATCAGGCAAATGATAAAAAAGTGGCTGCTATTGAAGTCCTAAATGATGGTGAACTCCAGAAAGCCATTGACTTATTCACAGATGCCATCAAGCTGAATCCTCGCTTGGCCATTTTGTATGCAAAGAGGGCCAGTGTCTTCGTCAAATTACAGAAGCCAAATGCTGCCATCCAAGACTGTGACAGAGCCATTGAAATAAATCCTGATTCAGCTCAGCCTTACAAGTGGCGGGGGAAAGCACACAGACTTCTAGGCCACTGGGAAGAAGCAGCCCATGATCTTGCCTTTGCCTGTAAATTGGATTATGATGAAGATGCTAGTGCAATGCTGAAAGAAGTTCAACCTAGGGCACAGAAAATTGCAGAACATTGGAGAAAGTATGAGCGAAAACATGAAGAGCGAGAGATCAAAGAAAGAATAGAACGAGTTAAGAAGGCTCAAGAAGAGCAGGAGAGAGCCCAGAGGGAGGAAGAAGCCAGACGACAGTCAGGAGCTCACTATGGCCCTTTTCCAGGTGGCTTTCCTGGTGGAATGCCTGGTAATTTTCCCGGAGGAATGCCTGGAATGGGAGGGGACATGCCTGGAATGGCCGGAATGCCTGGACTCAATGAAATTCTTAGTGATCCAGAGGCTCTTGCAGCCATGCAGGATCCAGAAGTTATGGTGGCCTTCCAGGATGTGGCTCAGAACCCAGCAAATATGTCAAAATACCAGAGCAACCCAAAGGTTATGAATCTCATCAGTAAATTGTCAGCCAAATTTGGAGGTCAAGCATAATGCCCTTCTGATAAATAAAGCCCTGCTGAAGGAAAAGCAACCTAGATCACCTTATGGATGTCGCAATAATACAAACCAACGTACCTCTGACCTTCTCATCAAGAGAGCTGGGGTGCTTTGAAGATAATCCCTACCCCTCTCCCCCAAATGCAGCTGAAGCATTTTACAGTGGTTTGCCATTAGGGTATTCATTCAGATAATGTTTTCCTACTAGGAATTACAAACTTTAAACACTTTTTAAATCTTCAAATATTTAAAACAAATTTAAAGGGTCTGTTAATTCTTATATTTTTCTTTACTAATCATTGTGGATTTTTCCTTAAATTATTGGGCAGGGAATATACTTATTTATGGAAGATTACTGCTCTAATTTGAGTGAAATAAAAGTTATTAGTGCGAGGCAAACATAA
>NM_003932.5
CTTGCGGCAGCCGCCCCCTTCTGCGCGGTCACGCCGAGCCAGCGCCTGGGCCTGGAACCGGGCCGTAGCCCCCCCAGTTTCGCCCACCACCTCCCTACCATGGACCCCCGCAAAGTGAACGAGCTTCGGGCCTTTGTGAAAATGTGTAAGCAGGATCCGAGCGTTCTGCACACCGAGGAAATGCGCTTCCTGAGGGAGTGGGTGGAGAGCATGGGTGGTAAAGTACCACCTGCTACTCAGAAAGCTAAATCAGAAGAAAATACCAAGGAAGAAAAACCTGATAGTAAGAAGGTGGAGGAAGACTTAAAGGCAGACGAACCATCAAGTGAGGAAAGTGATCTAGAAATTGATAAAGAAGGTGTGATTGAACCAGACACTGATGCTCCTCAAGAAATGGGAGATGAAAATGCGGAGATAACGGAGGAGATGATGGATCAGGCAAATGATAAAAAAGTGGCTGCTATTGAAGCCCTAAATGATGGTGAACTCCAGAAAGCCATTGACTTATTCACAGATGCCATCAAGCTGAATCCTCGCTTGGCCATTTTGTATGCCAAGAGGGCCAGTGTCTTCGTCAAATTACAGAAGCCAAATGCTGCCATCCGAGACTGTGACAGAGCCATTGAAATAAATCCTGATTCAGCTCAGCCTTACAAGTGGCGGGGGAAAGCACACAGACTTCTAGGCCACTGGGAAGAAGCAGCCCATGATCTTGCCCTTGCCTGTAAATTGGATTATGATGAAGATGCTAGTGCAATGCTGAAAGAAGTTCAACCTAGGGCACAGAAAATTGCAGAACATCGGAGAAAGTATGAGCGAAAACGTGAAGAGCGAGAGATCAAAGAAAGAATAGAACGAGTTAAGAAGGCTCGAGAAGAGCATGAGAGAGCCCAGAGGGAGGAAGAAGCCAGACGACAGTCAGGAGCTCAGTATGGCTCTTTTCCAGGTGGCTTTCCTGGGGGAATGCCTGGTAATTTTCCCGGAGGAATGCCTGGAATGGGAGGGGGCATGCCTGGAATGGCTGGAATGCCTGGACTCAATGAAATTCTTAGTGATCCAGAGGTTCTTGCAGCCATGCAGGATCCAGAAGTTATGGTGGCTTTCCAGGATGTGGCTCAGAACCCAGCAAATATGTCAAAATACCAGAGCAACCCAAAGGTTATGAATCTCATCAGTAAATTGTCAGCCAAATTTGGAGGTCAAGCGTAATGTCCTTCTGATAAATAAAGCCCTTGCTGAAGGAAAAGCAACCTAGATCACCTTATGGATGTCGCAATAATACAAACCAGTGTACCTCTGACCTTCTCATCAAGAGAGCTGGGGTGCTTTGAAGATAATCCCTACCCCTCTCCCCCAAATGCAGCTGAAGCATTTTACAGTGGTTTGCCATTAGGGTATTCATTCAGATAATGTTTTCCTACTAGGAATTACAAACTTTAAACACTTTTTAAATCTTCAAAATATTTAAAACAAATTTAAAGGGCCTGTTAATTCTTATATTTTTCTTTACTAATCATTTTGGATTTTTTTCTTTGAATTATTGGCAGGGAATATACTTATGTATGGAAGATTACTGCTCTGAGTGAAATAAAAGTTATTAGTGCGAGGCAAACATAACTCATTTGAGGATAAAGTTTGTGTTGGATATGTGGTTCCTGATGCATTTTGACTTGTCTTTTTAAATGCTTTATCTTTTTCTTTAAAGATTTATTTCAATAAAACTAATTGGGACCACCCGTATTTCAGTAGGACCTGGGTAGGGATTGGAAGTACTTGGCAGGGCAGCAGCAATCTTGCTGTGTTTGATATAACATGCATCCTTGGGCAGGTTGCCCTTAAATCTTACACTGTGGTGAAGGGATGTTTTTTTTGTAATGCTGCAGTAGAGTTGGAGTACTTAGTTCTCTTGTTGTCCAGTATATCTAATAAGTGTTTTTCATATTATTTCCACGTAAGGGAAATAAGGTAGTACTTTTCTTTTTATATTTCTATGCTTAAAATTCTCTTTCCTAGTCAAAAATTGCCCAAATCTGTGTTTGCTTTCTGCTTGCTACATTTGTCTCCCTTACTTTTCTTGAGCTAAAGACAGGCTTTTTCCACCGGCATCATCACTGCTATCATCATTAACAGCGTAATTATACAAGCATATTTAATGCTGAGTTTAATTTAATATGTAATACATATGGTAATTGTAGGGTAATACCCACAACAACTGTAGTTTCTTACTTGGCCAAGAGAATGCTTATTTAAGTGTTAGACTTCCATTCTGGCAAAATCTTGCCTTATCAGAAGACATTGGAAAGAGGGATTCCCTTTGGTGTTTGGTCTTCTACTTAGAAAAACCTATTGCAGTTAGTTTATCTTGTAGTATTCATCTTTGTATTCTGAAGATAAGGTTTGAATTAAATTGATACACACAGAGGGGAACCGATTTTTTTTATCCAATGTGAATTATAAATGAGATAATCCACAGTTATTCATTGTGGAGTTGTTGAGACTATGAAAGACTCATTGTCTTTGTATTCAGCTCTTAAATAGTGTAACTATATCCCCACCTCTGCTTGCTTTCTTTCCCTCCCCTCCAATGATAAAGAAAATGATAAATTTTCTGTTGTGCATTCAATTCTTATTTTAAATAAGACTAAGTATAGGCATTGTACCTGACATTGCTACGTTTCTACCAGTGTTTCAATTTAAAGTGCTAGTGTTTAAAAACATTTTCAAGGGATAAGGCCTTCTGTACTTTGCTTATTTGAAGAATCAGTGGTAGGAGCAGTGAAGTAAATTCTATGGAGTACATTTCTAAAATACCACATTTCTGAAATCATAAATAAGTTTATTCAGGTTCTAACCCTTTGCTGTACACAAGCAGACAGAAATGCATCTGTTACATAAATGAGAAAAAGCTATTATGCTGATGGAGCATGCTTTTTAAATCCTTTAAAAACACTCACCATATAAACTTGCATTTGAGCTTGTGTGTTCTTTTGTTAATGTGTAGAGTTCTCCTTTCTCGAAATTGCCAGTGTGTACTTGGCTTAACTCAAGAACAGTTTCTTCTGGATTCCTTATTTGATTTATTTAACCTAATTATATTCTAATATTGCAAATATTACCATAAGTGGGTAAAAGTAAAATTCCTCTTCTGAAAATGTGTCCTGTGCTTTTAGATTTTTAAATTCCATAATATACATTCTTAATTTTCAACTCAA

Publications

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