Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name MTCH1P2
Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr11:18595022-18596286  UCSC
Coordinates (T2T) chr11:18693106-18694370  UCSC
Coordinates (hg19) chr11:18616569-18617833  UCSC
Strand -
Parental Sequence NM_001271641.2
Parental seq. overlap 1089 bp
Parental seq. overlap (%) 55.4%
Genomic Region Intergenic
Retrocopy Summary MTCH1P2, located on chr11:18595022-18596286, is a retrocopy of the parental gene MTCH1. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name MTCH1
Full Name mitochondrial carrier 1
Also known as CGI-64|PIG60|PSAP|SLC25A49
Coordinate chr6:36968135-36987171
Strand -
Gene summary This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Oct 2012]

Homology

Species Scientific Name Retrocopy
Gorilla Gorilla gorilla MTCH1P2
Orangutan Pongo abelii MTCH1P2
Gibbon Nomascus leucogenys MTCH1P3
Green monkey Chlorocebus sabaeus MTCH1P1
Crab-eating macaque Macaca fascicularis MTCH1P2
Rhesus Macaca mulatta MTCH1P2
Baboon Papio anubis MTCH1P2
Golden snub-nosed monkey Rhinopithecus roxellana MTCH1P2
Chimpanzee Pan troglodytes Without Homology
Bonobo Pan paniscus Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>MTCH1P2
GAAGGTTTTCCCTCCAGATGAAATCAAGCAGGTTTCCAATAAGGATGGATATGAAGACTTCTCTGAAGCAAGCAGTGAAGGAGACCTCCTAGGGGATGATGATGCAGTGTGCGTCCTGTATGTTGGCCCACCCCCTGCATGCCATCTTGATGTGCTGCATGGTCTAATTTGTGGGATGGGAGGTTAAGTACAGTGGTGTGCTGAGCTCCACTGGGAAGATTTTCAAAGAGAAAGGGCCACTGGGATTCTTTGTTGGCTTGATCCCTCATGTCCCGGGTGAAGTAGTTTTCTTGTGAGGCTATAACCTGCTGGCCCACTTTATCAATGCCCACCTGGCGGATGACAGAGTGAGTGACACCTAGAGGGGCTGAGAAATGACCAGAATCGGGGTTCCCAGTTAGGCCAGGCCCTGACCATCCAAAGCTACACCAAGTTTGTGATGGAGATCGCAGTGAGCATGCTGACCTACCCTTTCCTGCCAGTTGGCAGCCTCATGGCTGTGAACAACTGCAGGCCGCAGGCTGGGCCCTCTCCTTACTCCCTGGTGTTCAAATCCTGGATTTACTGCTGTAAGTACCTGAGTGTGCAGGGCCAGCTCTTCTGAGGCTCCAGCCTGCTTTTCCCCACGTGTCATCAGGATCATGCTTTCGCCTGGAGCAACGTGAATCATCTTTAAAAAAAAACAACTGCTGTCTCAACATGGCCACTGTGGGTGAGGCCTGATTATCTCAGGATATCTGCAAGATGACTCCAATGCAGCAACAACCAGATGTGCTCCAGCCCAGCTGGGCTTCAGTTTCCATATTTGCCATGTGTTTGTCCAGATGTGGGGTCAGGTGGGGGTGGGGCTGCACCCTGGGGATTAGATCGCCTGCCAAACCTGGGGGAGGTGGGGCTAGGTGGGGAATTGGCAGAATCCCCATACCTCCCAGATTTGCTGAGTCTGCCTTGTCCAGAGGGCCAGAGAACGGCTTTTGGAGGCCCAGATTGGATGGGGAAAGCCTAATCAGGTCAGATCCCACCCCTGTCCAAGCCCCCAGTTGGTCCAGCTCCTATCTTGCAGCTCAGCTGAAAGCATCATTCTTCTGCACAAGGCCACTAGCATGTTTCAGCCTGTGCTAGGAGGCAAATGCTAGGCTCTGCCTTTATTTTTCTCAACACTACTTTTGATACAAGGGCAGTATCTTCCTCTGAATAGCTAATCATGTGATTAGTCAGAATGCATCCCCCTCATCTAATGCTCATGTATTTACTGGTGATGCCTT
>NM_001271641.2
GAGTGACCTCGCCGCCGGGCGCCATGGGAGCTTCGGACCCGGAAGTGGCGCCCTGGGCTCGCGGCGGTGCCGCGGGGATGgcgggagccggagctggagccggagctcgcggcggagcggcggcgggggtcgaggctcgagctCGCGATCCACCGCCCGCGCACCGCGCACATCCTCGCCACCCTCGGCCTGCGGCTCAGCCCTCGGCCCGCAGGATGGATGGCGGGTCAGGGGGCCTGGGGTCTGGGGACAACGCCCCGACCACTGAGGCTCTTTTCGTGGCACTGGGCGCGGGCGTGACGGCGCTCAGCCATCCCCTGCTCTACGTGAAGCTGCTCATCCAGGTGGGTCATGAGCCGATGCCCCCCACCCTTGGGACCAATGTGCTGGGGAGGAAGGTCCTCTATCTGCCGAGCTTCTTCACCTACGCCAAGTACATCGTGCAAGTGGATGGTAAGATAGGGCTGTTCCGAGGCCTGAGTCCCCGGCTGATGTCCAACGCCCTCTCTACTGTGACTCGGGGTAGCATGAAGAAGGTTTTCCCTCCAGATGAGATTGAGCAGGTTTCCAACAAGGATGATATGAAGACTTCCCTGAAGAAAGTTGTGAAGGAGACCTCCTACGAGATGATGATGCAGTGTGTGTCCCGCATGTTGGCCCACCCCCTGCATGTCATCTCAATGCGCTGCATGGTCCAGTTTGTGGGACGGGAGGCCAAGTACAGTGGTGTGCTGAGCTCCATTGGGAAGATTTTCAAAGAGGAAGGGCTGCTGGGATTCTTCGTTGGATTAATCCCTCACCTCCTGGGCGATGTGGTTTTCTTGTGGGGCTGTAACCTGCTGGCCCACTTCATCAATGCCTACCTGGTGGATGACAGCGTGAGTGACACCCCAGGGGGGCTGGGAAACGACCAGAATCCAGGTTCCCAGTTCAGCCAGGCCCTGGCCATCCGGAGCTATACCAAGTTCGTGATGGGGATTGCAGTGAGCATGCTGACCTACCCCTTCCTGCTAGTTGGCGACCTCATGGCTGTGAACAACTGCGGGCTGCAAGCTGGGCTCCCCCCTTACTCCCCAGTGTTCAAATCCTGGATTCACTGCTGGAAGTACCTGAGTGTGCAGGGCCAGCTCTTCCGAGGCTCCAGCCTGCTTTTCCGCCGGGTGTCATCAGGATCATGCTTTGCCCTGGAGTAACCTGAATCATCTAAAAAACACGGTCTCAACCTGGCCACCGTGGGTGAGGCCTGACCACCTTGGGACACCTGCAAGACGACTCCAACCCAACAACAACCAGATGTGCTCCAGCCCAGCCGGGCTTCAGTTCCATATTTGCCATGTGTCTGTCCAGATGTGGGGTTGAGCGGGGGTGGGGCTGCACCCAGTGGATTGGGTCACCCGGCAGACCTAGGGAAGGTGAGGCGAGGTGGGGAGTTGGCAGAATCCCCATACCTCGCAGATTTGCTGAGTCTGTCTTGTGCAGAGGGCCAGAGAATGGCTTATGGGGGCCCAGGTTGGATGGGGAAAGGCTAATGGGGTCAGACCCCACCCCGTCTACCCCTCCAGTCAGCCCAGCGCCCATCCTGCAGCTCAGCTGGGAGCATCATTCTCCTGCTTTGTACATAGGGTGTGGTCCCCTGGCACGTGGCCACCATCATGTCTAGGCCTATGCTAGGAGGCAAATGGCCAGGCTCTGCCTGTGTTTTTCTCAACACTACTTTTCTGATATGAGGGCAGCACCTGCCTCTGAATGGGAAATCATGCAACTACTCAGAATGTGTCCTCCTCATCTAATGCTCATCTGTTTAATGGTGATGCCTCGCGTACAGGATCTGGTTACCTGTGCAGTTGTGAATACCCAGAGGTTGGGCAGATCAGTGTCTCTAGTCCTACCCAGTTTTAAAGTTCATGGTAAGATTTGACCTCATCTCCCGCAAATAAATGTATTGGTGATTTGGA

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