Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DNAJA2P1
Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chr16). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr11:34404108-34404951  UCSC
Coordinates (T2T) chr11:34540822-34541665  UCSC
Coordinates (hg19) chr11:34425655-34426498  UCSC
Strand -
Parental Sequence NM_005880.4
Parental seq. overlap 747 bp
Parental seq. overlap (%) 24.8%
Genomic Region Intergenic
Retrocopy Summary DNAJA2P1, located on chr11:34404108-34404951, is a retrocopy of the parental gene DNAJA2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DNAJA2
Full Name DnaJ heat shock protein family (Hsp40) member A2
Also known as CPR3|DJ3|DJA2|DNAJ|DNJ3|HIRIP4|PRO3015|RDJ2
Coordinate chr16:46955362-46973674
Strand -
Gene summary The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro. [provided by RefSeq, Jul 2008]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes DNAJA2P1
Bonobo Pan paniscus DNAJA2P1
Gorilla Gorilla gorilla DNAJA2P1
Orangutan Pongo abelii DNAJA2P1
Gibbon Nomascus leucogenys DNAJA2P1
Crab-eating macaque Macaca fascicularis DNAJA2P1
Rhesus Macaca mulatta DNAJA2P1
Baboon Papio anubis DNAJA2P1
Golden snub-nosed monkey Rhinopithecus roxellana DNAJA2P1
Green monkey Chlorocebus sabaeus Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>DNAJA2P1
GAGGTGAAGAAATGCCACAATATCCTAATCCCTTTGAACAAGGTGATCTTTACATAAAGTTTGATGTGAAGTGTCCTGAAAACAACTGGAACAACCCAGACAAACGTTCTCAACTAGAAGATCCGCTGCCATCTAGATCAGAAGTTTCAAACACAATTGGAGAAAAAGTGGCGGTAGAGCTTCAGGAATGTGATAACACTTGAGGCTGAGGAGGTGGTCAGAGGCATGAAGCCTAAATCATAGCTCTGATGAAGAAAACAGCAGCCCTCATGTTCCTGGAGGTGTGTGCCTGCCCATCCGCAAACACTGCAAATGAATTGCACAGGAGGACTTTCCTTCCACACTTGCCTGATTTGTTCTCAGCGATCCCACTGGAGTGTCCCATCAATCCAGATGAACTGATGGACATCCATTGGTCTCTGCGTAACTTTTAAAATTGGTATAGTATCTACAGCGTGTATAATTGAAACTAACCACAAAGCTTCACATCTTCGTTTCAACTGTTCCATAGCAGAATAAAGCACTTGAAAGGAAATAAAACTCCCTTTCACATGTAGATTATAAGTTTCGATCCTGATATCTGTGCTTGATTTTTATCAGTTTTGTGCAGACTTTATGTCTCATATTTTAAATTCAAATCCCATATTGTAAAGTTTGTACAATTTATCCTGAAGCTTTGTGTTTGGCTGCACCTGAATAAGCTGCTACAAATAGAAGAAAGAATCTCATAGCCTGTATCTATCATTTAGATGTATGGGAAAAATAGGTCTTGCACACAATGAGTTTGGAGCTGAGTAGGAACAATGGAAAAAAATGACATTAGCTGTGGTTGTAAAg
>NM_005880.4
GCTGTCTCCCTCGGCCTGTGCCGCCGCCGACGCCGCTTGTGGGCCCGACTCCGCTCTGTCTGCTTCGCCACCTTCTCCCCGAGCACTGCCCGGCCGGCCGCCATGGCTAACGTGGCTGACACGAAGCTGTACGACATCCTGGGCGTCCCGCCCGGCGCCAGCGAGAACGAGCTGAAGAAGGCATACAGAAAGTTAGCCAAGGAATATCATCCTGATAAGAATCCAAATGCAGGAGACAAAtttAAAGAAATAAGTTTTGCATATGAAGTACTATCAAATCCTGAGAAGCGTGAGTTATATGACAGATACGGAGAGCAAGGTCTTCGGGAAGGCAGCGGCGGAGGTGGTGGCATGGATGATATTTTCTCTCACATTTTTGGTGGGGGATTGTTCGGCTTCATGGGCAATCAGAGTAGAAGTCGAAATGGCAGAAGAAGAGGAGAGGACATGATGCATCCACTCAAAGTATCTTTAGAAGATCTGTATAATGGCAAGACAACCAAACTACAACTTAGCAAGAATGTGCTCTGTAGTGCATGCAGTGGCCAAGGCGGAAAGTCTGGAGCTGTCCAAAAGTGTAGTGCTTGTCGAGGTCGAGGTGTGCGCATCATGATCAGACAGCTGGCTCCAGGGATGGTACAACAGATGCAGTCTGTGTGCTCTGATTGTAATGGAGAAGGAGAGGTAATTAATGAAAAAGACCGCTGTAAAAAATGTGAAGGGAAGAAGGTGATTAAAGAAGTCAAGATTCTTGAAGTCCACGTAGACAAAGGCATGAAACATGGACAGAGAATTACATTCACTGGGGAAGCAGACCAGGCCCCAGGAGTGGAACCCGGAGACATTGTTCTTTTGCTACAGGAGAAAGAACATGAGGTATTTCAGAGAGATGGGAATGATTTGCACATGACATATAAAATAGGACTTGTTGAAGCTCTATGTGGATTTCAGTTCACATTTAAGCACCTTGATGGACGTCAGATTGTGGTGAAATACCCCCCTGGCAAAGTAATTGAACCAGGGTGTGTTCGTGTAGTTCGAGGTGAAGGGATGCCGCAGTATCGTAATCCCTTTGAAAAAGGTGATCTTTACATAAAGTTTGATGTGCAGTTTCCTGAAAACAACTGGATCAACCCAGACAAGCTTTCTGAACTAGAAGATCTTCTGCCATCTAGACCGGAAGTTCCTAACATAATTGGAGAAACAGAGGAGGTAGAGCTTCAGGAATTTGATAGCACTCGAGGCTCAGGAGGTGGTCAGAGGCGTGAAGCCTATAATGATAGCTCTGATGAAGAAAGCAGCAGCCATCATGGACCTGGAGTGCAGTGTGCCCATCAGTAAACTCTGCAAACAAATTGCACAGGTGGATTTTCTTTCCACATTTGCCTGATTTGTTCTCAGCAATCCAGCTGGAGTGTCTTATCAATCCAGATGAACTGAGGGACATCTGTTGGTCTATGTATAACTTTTAAAATTGGTATAGTATCTACAGAGTGTATAATTTAAACTAACCACAAAGCTTTACATCTTCATTTTGACTGTTCCATAGCAGAATAAAGCACTTGAAAGGAAACAAGACTCCCTTTCACACATGGATTATTATAAGTTTCAATCCTGGTATCTGTGCTTGATTTTTATCAGTTTTGTGTAGATTTTTATGTTTCATATTTTAAATTTAAATCCCACATTGTAAAGTTTGTACAATTTGTCCTGAAGCTTTGTGTTTGGCTGCACCTGCATAAGCTGCTACAAATAGAATAAAGAATTTCATAGCCTGTATCTATCATTTAGATGCATGGAAAAAAATGGGCTTTGCACACAATGGGTTTGGAGCTGACTGGGAACAATGGAAAAAATTACATTAGCTGTGGTTGTAAAGtttttttgtttttggttttgttttttttttcttttttctttttttttttttttACCATCTTGTGAAAGGTTTCTGAAACTCGATAATAAAAAGCGGTTGGTGTAAATTATTCTTTTGTGTCACATTTTTAGAAGGAAAAACATAAAAGAATGTATCCTTAGTACTGGTTCTTAAACAGCCCATAAAAACCCATTGGCCTGAAGCTTATATCTCAGGCCTATGCCCATCTTATAGTCTTGGAAGACAAAAGGCTGGTAGAGACAGTCTTCAGTGGCTTCAGTGATGCTCTGTAGAGGCCAGGGTGTCTTGAGTGCTGTAACTCCCAAGCACTGGGCTAGCCTGACTTCTGTATCTCCCTACCACCACCCCCTTAAAAAAATAAGGTAACAGCAAATCTATAGTAAAACCATGTCTGCATAGAACGTGTTCAAATCCTCTGTTTTCATTAAATGTAAAAGATGCTGTCTCCATTAAGTTGAATATTTGGAATTGGAGAAGCCATTGATTATTATTTTGAGTTTCTGTAATGTTTTATAGAAAAGTAAGATGCTTATTCAGAATTTAAGAATGAAGGCAACTGAAATATGCATTGTTGTAGTTATTTATATTTCAAACTAAAAATAAGCAAAAAAAAAAGGCTGGTTTGAGAAAAATCAGGTAAAATTGATGAAACGGATGTTGTGTTTCTCTTTCCATCATCTGGTTTTTACCATTTCACTCAGTAGGTATTTTTAGAACACACTTATTTGAGGAAAGAGACATCAGATGCACAATTTTACATTTATAAAGGAACAAATGGGGAAAACTGAAAACTAAAAATTTTAAATGTATTAAATGCCATCCCTGAGCCTAAATCTAGTATTTGTAGTTTATTTCTAGGTCTGCTAGAACCTGAAAACCTGAATGAAAAAAGGTGTGCTGACACTAATCAAGTCCTGTGAGGTTTAAATTATTGACCTATCCACTCTACCTCCATTGTACAAAAAATATTTTACAACAAGCCTGGGTAAGATTCAACAGCATAGTAGTTTTGTATCCAAGGTTACTTCCCCACAACCACTTTAAACATAAGAAATGTGGTGGCAATATAAAGTTTGTAGCCTTTCCAATAAAGGTTTATAAAACAGTT

Publications

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