Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name WEE2P1
Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chr7). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr11:35965765-35968646  UCSC
Coordinates (T2T) chr11:36104459-36107340  UCSC
Coordinates (hg19) chr11:35987315-35990196  UCSC
Strand -
Parental Sequence NM_001105558.1
Parental seq. overlap 2125 bp
Parental seq. overlap (%) 67.1%
Genomic Region Intragenic (LDLRAD3)
Retrocopy Summary WEE2P1, located on chr11:35965765-35968646, is a retrocopy of the parental gene WEE2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name WEE2
Full Name WEE2 oocyte meiosis inhibiting kinase
Also known as OOMD5|WEE1B
Coordinate chr7:141708353-141731271
Strand +
Gene summary Predicted to enable protein tyrosine kinase activity. Predicted to be involved in several processes, including female pronucleus assembly; negative regulation of oocyte maturation; and regulation of meiosis I. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes WEE2P1
Bonobo Pan paniscus WEE2P1
Gorilla Gorilla gorilla WEE2P1
Orangutan Pongo abelii WEE2P1
Gibbon Nomascus leucogenys WEE2P1
Green monkey Chlorocebus sabaeus WEE2P1
Crab-eating macaque Macaca fascicularis WEE2P1
Rhesus Macaca mulatta WEE2P1
Baboon Papio anubis WEE2P1
Golden snub-nosed monkey Rhinopithecus roxellana WEE2P1
Marmoset Callithrix jacchus WEE2P1
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>WEE2P1
TGCATTTTTAAATAAAGCATTTTATCTTGTCGAAAGACAAATTACAGGTAGAGTACTCTTCTTTGTCATACCGTCACTAACAAAGAATGAAAAATTTACGTTAGAGAACATTTTACGTGATAAAAGGGTAAGAGAATTCAGTAGGTCAGTAGTAACATGCCTTGGCAGTAGGGCCCAGATTCACAGATCCAAAAGTTAATAACAGTCAGGATCTGCTATAAAATAATGTTGGTCATAAAGGTATTTGATAAATTGTTTGTGTCATCTTAATGAATGCAACCTGTTAATGATTAATGGCTTTTTTTACTGTTGGATTTTCTTCTTTTCCTGATTTTAAAAAGCGAATTTTTTAAATTGAATAAACCCTCACACTATTCTTTAGAGACTCAGAATGTAGGGCAAAAGAAAGCACAGGGAAGCAGGGAGGCCCAGAGCCAGATCCCAGAGAAGAGTGAAGTGCAGAATTCAGAGGCAATGCTTACATTGCCCAGGACTCCTCTCAGTAACGTGCATGAACTCAACACACCTCGGGAAAAAGAAAAAGAAGATCCAGATCAGATTTTGAGGACTCCAGTGTCACACCTTCTCAAATATCCTGAGACACCAGGCCAACCAGGCAACAGGAACAAGCAGCCACATGGTGCCAGCCCCTCTACTCCCAAAAGCCCGCTGAGCCAGACGTTATTTCTCCAACAGCAAAGCCTCCTTCCAGAGGCTCTAAGCATTTGATGCTCACATCCACTCCTCCCAAGGATGAGATGACCTCACTGGCTCTGGTCAATACTAATCCCTTCACCCCAAAGTCCTATAGAAAATTATTCCTTCAATCCAGTGTCAAGAGGAAAATTCGAGATGATCTTGAGGAAGCTGGTCCAGAGGAAGGCAAGGAAGAACAAGGGCTGCCTGCTGAGACATGTGTTCTATGAGAAACCAACATGGCTTCCTACTATAAAAAAGAATGCTCGGAGGTAGAAAAAATTGGGGTTGGTGAATTTGGTACAGTCTACAAGTGCATTAAAAGCCTGGATAGAAGTGTTTATGCAATAAAGCACTATATGAAAACTTTTTCAGGATTTCACCTGAGAATTTGGCTTTGCGTGAAGTTTATGCTCATACAGTGTTTGGACATCACCCCACCTGGTACATTACTACCCCTTACAGGCAGAAGATAACCATATGATCATTCAGAATGGATACTGCAATGGCAGGAGCTTGCAGGCTGCTATATCTGAAAACACTAAGTCTACTAATCACTTCCAAGAGCCAAAACTCAAGGACATCCTTCTACAGATTTCCCTTGAACTTAAATACAGCCACAACTCTGGCATGGTGCACCCGGACATGAAACCTTGTAAAACCTTCCTTTGTCACAAGATGCAAAGTGACTCCTCTGGAGTCACAGAAGTTGAAAATGAAGCTGATTAGTTTCTCTCTGCCCATGTGATATATAAAATTGGTGACCTAGGCCATGTGACATCAATAAGCAAACTCAAAGTGGAAAAAGCAGATAGTTGCTGCCTAGCAAATGAGATTTTGCAAGAGGATTATTAGTACCTTCCCAAAGCAGACCTATTTGCCTTGGGATTAATCACTGCAATGGCTGAAGGAGTAAGGACATTACCCATCAACAGTGCTGCAAGGCACCATAACCATGAGAGTAACTTCCCAGACATTCCTCAGGAGCTCTCAGAAGACTTTTACAGTCTGCTCAAGCACATGATCCACCCTGATCCAGGAGAGAGACCTTCTGCAGCAGCTCTGGTCAGAAATTGGCCCTGGCCCTCCCTGGGGAAAGCAGAAGAGCTCTAGCAGCAGCTGAATTTGGAAAAGTCCAAGACAGCTGCACTGGAAAGGGAACTAAGGGAAGCCCAGCAGGCCCAGTCCCTGCAGGGAGACTTCCATCATGGTGACCCTCGGGTCTTTGGGACCACACGGGATCAGAAAACACCAAATGCCTGGTAGGAGGAAAGAGTGCAAGGTCTTCAAGCTTTACCTCAGGACAGCATGAGCCTCTGAACTAAAGGAAGAAAACAGGAAACAGCCCTTGCTTGGCCTTATGGATTAGGAGGTTGCCCTACCAAGGATCCCAGGGATTCGCTGTACATAGAAAGGAATAGAATTTGGTTTTGAATTCAAGTAACAGTTTACAAGAAAATGTGCCTGGATTTCCACAGTACTTCCCAGGTTATATGATGCTATTTCTGAAAAAGAGTTCCCAACCCCTTTGTGGAAGTGGGTCTCCTAATATATATACCCTTTCTGATATTGTATTTACTAAATAAATGGCTTCACCATTACATGAGGTGGGTAAAAGTAAGACTGTATATAACTTGGACATCTCTGAGCTGGTTGTTTAATTGCAGAACAAAAACGCTGGATGGAGAAGGTTCAAGGAAAACTTGACATGGCTGTTCTCCATCTACTTGCCCTGTCCCTCTTGTGGCCACGTTCTGACTGGTTTGATGTTCCAAGCCTCACCAATTTCCCTTTATTTTATCAGAATTTGGCCTTGTTTCCTATTATTTCATCATACTTTATCCAAATCCTTTTTATGTACACATTTTTAAAGGAAAAGAATACTGCAt
>NM_001105558.1
AATTTCTTTTCAATATTAGCTTATTCCCAAATTGGCTAATGGGTATTTTTAAAGCCATGCTAAATTAAAGGAATTCAATTTTCTCACTAGTATTTGGTAACACATGGGAGACTATGTGTCATATCCAGAAGAGTTCTGTACATGAACTGCATTTAATTGCTCCGAGAGTCACTGGAGCTTTCTTTAATCAGAATGGAAATCAGGATAAGCTGAGGTCTTATAGATTGGTGGTACTTAAGGCAGAAAATTAACACCGTGTTTTGTAGCTGTTAGTTGGTAGAGGGAAATTCAGGCTACCGTCGCGAAACCTGCAGGTTAAGTTATTTTCTCCTCCCTGCTTCTGTAGGTTCACAGCGTTCCCTTCTGATAGAGCTTTTTGTCTGTGTTGTAAAGCTCTTTGGCTGAGATGGATGACAAAGATATTGACAAAGAACTAAGGCAGAAATTAAACTTTTCCTATTGTGAGGAGACTGAGATTGAAGGGCAGAAGAAAGTAGAAGAAAGCAGGGAGGCTTCGAGCCAAACCCCAGAGAAGGGTGAAGTGCAGGATTCAGAGGCAAAGGGTACACCACCTTGGACTCCCCTTAGCAACGTGCATGAGCTCGACACATCTTCGGAAAAAGACAAAGAAAGTCCAGATCAGATTTTGAGGACTCCAGTGTCACACCCTCTCAAATGTCCTGAGACACCAGCCCAACCAGACAGCAGGAGCAAGCTGCTGCCCAGTGACAGCCCCTCTACTCCCAAAACCATGCTGAGCCGGTTGGTGATTTCTCCAACAGGGAAGCTTCCTTCCAGAGGCCCTAAGCATTTGAAGCTCACACCTGCTCCCCTCAAGGATGAGATGACCTCATTGGCTCTGGTCAATATTAATCCCTTCACTCCAGAGTCCTATAAAAAATTATTTCTTCAATCTGGTGGCAAGAGGAAAATAAGAGGAGATCTTGAGGAAGCTGGTCCAGAGGAAGGCAAGGGAGGGCTGCCTGCCAAGAGATGTGTTTTACGAGAAACCAACATGGCTTCCCGCTATGAAAAAGAATTCTTGGAGGTTGAAAAAATTGGGGTTGGCGAATTTGGTACAGTCTACAAGTGCATTAAGAGGCTGGATGGATGTGTTTATGCAATAAAGCGCTCTATGAAAACTTTTACAGAATTATCAAATGAGAATTCGGCTTTGCATGAAGTTTATGCTCACGCAGTGCTTGGGCATCACCCCCATGTGGTACGTTACTATTCCTCATGGGCAGAAGATGACCACATGATCATTCAGAATGAATACTGCAATGGTGGGAGTTTGCAAGCTGCTATATCTGAAAACACTAAGTCTGGCAATCATTTTGAAGAGCCAAAACTCAAGGACATCCTTCTACAGATTTCCCTTGGCCTTAATTACATCCACAACTCTAGCATGGTACACCTGGACATCAAACCTAGTAATATATTCATTTGTCACAAGATGCAAAGTGAATCCTCTGGAGTCATAGAAGAAGTTGAAAATGAAGCTGATTGGTTTCTCTCTGCCAATGTGATGTATAAAATTGGTGACCTGGGCCACGCAACATCAATAAACAAACCCAAAGTGGAAGAAGGAGATAGTCGCTTCCTGGCTAATGAGATTTTGCAAGAGGATTACCGGCACCTTCCCAAAGCAGACATATTTGCCTTGGGATTAACAATTGCAGTGGCTGCAGGAGCAGAGTCATTGCCCACCAATGGTGCTGCATGGCACCATATCCGCAAGGGTAACTTTCCGGACGTTCCTCAGGAGCTCTCAGAAAGCTTTTCCAGTCTGCTCAAGAACATGATCCAACCTGATGCCGAACAGAGACCTTCTGCAGCAGCTCTGGCCAGAAATACAGTTCTCCGGCCTTCCCTGGGAAAAACAGAAGAGCTCCAACAGCAGCTGAATTTGGAAAAGTTCAAGACTGCCACACTGGAAAGGGAACTGAGAGAAGCCCAGCAGGCCCAGTCACCCCAGGGATATACCCATCATGGTGACACTGGGGTCTCTGGGACCCACACAGGATCAAGAAGCACAAAACGCCTGGTGGGAGGAAAGAGTGCAAGGTCTTCAAGCTTTACCTCAGGAGAGCGTGAGCCTCTGCATTAAAGGAAGAAAAGGAAAACAGCCCTTGGTTTGGCCTATGGATTACGAGGTTGCTGTTGCTGATTCCCCACCAAAGATCCCAGGGACTCGTTGTACATAGAAAGGAATAGAATTTAGTTTAGAGTTGAAGTCACAGCTTACAGAAAATGTGCCTGGATTTCCACAGCGCTTCCCAGGTTATATGATGCTGTTCCTAAGAGAGAATTCCCAGCTTCTTTGAGGAAGTGGGTCTCCTAATGTATACCCTTTCTGATATTGTATTTATTAAATAAATGGTTTCACCATTATGTGAGGTGGGTAAAAGTTAGACTGCATGCAACTTGGACATCTCTGAGCTGGTTGTTAACTTGCAGAACAAAAATGCTGTGGGGAGAGGCTTCAGGGAAAACTTGATGTGCCTGTGGTTGTTCTCCATCTATTTGCCCTGCCTCTCTTGCTGTTCTGGTTGGTTTGATATTCTGGGTCTCACCAATTTCTCTTGATTTTTGTGAGAATTTGGCTTTGTTTCCTGTTTTTTAAAATCATATTTTATCTAAATCCTTTTTCTGTACACATTTTTAAAGGAAGAGAATACTGTATTTTTAAATAAAGGTTTTTATCTTGTCCAAAGCCTAATTACAGGTAAAATATCCTTTGTAAAATGTAACTAACAAAGAATGAGAAATTTATGTCGGAGAACATTTTATGAATAAAAGGGTAAGAGAATTGAGTGGGTCAGTAGTAACAGGTCTTGGTGGCAAGTCTCAGCTTCACAGTTCCAACAGTTAATGATGGTCAGGATCTGCTAGAAAATTATGTTGGTCATAAAGGTATTTGATAAGCTCTGTTTGTGTCATCTTAGTGAATGCAACCTGTTAATGATAATGGCTTTTTCGCTGCTTGATTTTCTTCTTTTCCTCATTTTTAAAAGCTAATTAAGTTTTTTTAATTGAATAAACCCTAATACTATTCTTT

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