Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name RDXP1
Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chr11). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr11:4207938-4212298  UCSC
Coordinates (T2T) chr11:4272984-4277346  UCSC
Coordinates (hg19) chr11:4229168-4233528  UCSC
Strand -
Parental Sequence NM_002906.4
Parental seq. overlap 2848 bp
Parental seq. overlap (%) 54.2%
Genomic Region Intergenic
Retrocopy Summary RDXP1, located on chr11:4207938-4212298, is a retrocopy of the parental gene RDX. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name RDX
Full Name radixin
Also known as DFNB24
Coordinate chr11:110174922-110296614
Strand -
Gene summary Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes RDXP1
Bonobo Pan paniscus RDXP1
Gorilla Gorilla gorilla RDXP1
Gibbon Nomascus leucogenys RDXP1
Orangutan Pongo abelii Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>RDXP1
AGAGAGATGCTAACCTTGTAGCATATGAAGAATGTCTGTACTTTGATATGATAGTTACATAATCAGTATATTTGGTTTCTAGATCACTGTGCTTATTTTTTTAATCTCTAACTAAAAATGCTTAAAATTTGGTTTGTTAATTCTATTTTAGAAATTATAATTTTAGTTTATATTAACTTCATTTATATGTTACTGAAGAAATCTTTCCAGTTAGGAGGAGGTTCTAATAGTCACATGTTCTAATACTTTGTTTATTGTAAAACCGCTAAATTTGGAGATATGTAAAGCCTTGTTTTCTCCGTGTGGTTCAGCTACTTTCCATTTGGAATTACTCAAATTTACATTTATCTATTAAAATTGCCTTTTATTAAACATTTTCATGCACAGTAGATTCAAGTTGTGTCTGAAAATATCTCTTTTGCTTTTTTGATTTTGCTGACTTTAAAAGGATTAATCTGGGCAGACATTATGAAAAGGAAAGGTTGTGTTTAATATATTTTTTTAACTTTGTAGGACAAAACATAGCTGGTTAACCTTGAAGTGACTGTTGTACCATGGTTGTGCACATGCTTCAGAATCCTATGGAAGAGAATGTTCCTACTTGCAGTACATCAAAGGAATGGATGGTGGACCCTGCTATTCATGTTTTGAAACATAAATGTTCACTTTAAAGCAATTGCCATAACAGATAAAAACCTGAACTTTCATTGGATTTTTGTTAATTTTCCTCATTTTGAATTATGTGCACTACCATAGCTATATCAGCTTGATACAGTATTGAAAAATTATCAGTTATATTTTGCTGTTTATGATCTATTTGTAGATTAGGATTAAAATGGATTTAATTCATTTTTAAGGCTGTGTGAATTTTTCTAAACAAGAACCATTTAAAATATGGATTTTCATAGAGATTAAACCAATTATAACTCATCATTAGCAGTCACAAGCACATGTTCATATAGTCAATGTAAAAATACACTAATGAGTATTTGGTAAATCCCAGTAGGCTTTTACCATTAGCATAATTTTGTGCTGTACAATTAAGTTACAATTATATCTCTAATTTTGGATAATATTCTAATATTCATTGGTTAACAATAAAGTGACAAAAGCTaGTCATTCCTTCGACAGAAAACGAACATGATGAACATGATGAGATTAATGCTAAGGCTGGTGCTGAATTATCAAATGAAGGGGTAATGAACCATAGAAGCAAAGAAGAACATGTAACAGAAACACAGAAAAATGAGCGTGTTAAGAAGCTACTTCAGGCCTTAAGTTCAGAATTAGCCCAAGCCAGAGATGAAAGCAAGGAAACACAAAAGGATGTTCTTCAGGCTAAGAATGTTAAAACAGGCCATGGTAAGTACAAGACTCTGTGACCGATTCGACAAGGCAACACAAAGCAGCGTATCAATGAGTTTGAAGCAATGTGAGAGCTGTTATTTTGCATATGTATTCTTCATAAGCTGAACTGCCAACAGAGAAAAGCAGGCCTTTGCAGATAGGATGGAATGCATCCCACCTTGCAAAAGCACTTACACCAGTTTGACTGTGCTAGCTAAAAGACATATTTAAGGGGAGCTCTTCAACATTAAGGCAGTCTGATATCATACTTGGTTTTCTTTTTCTTTTGGTCCAGGAATGGAGAATGGTGTTCCATTGCCTTTTTTCACATATTTTTCTTTTTCCTTTTTTTTTCTATTGAAGATTAACACTAATTATCATGTCTGACAAATGTGTATCTGTGGTTTCAGTTTCATGCACATTTTAAAGGATAATGGTGAACATTTTAAAGGGTTTCCCTTGCCCCTTCCATACTTAACCTGTGTATATTTCCACATTCCCTCTCACTCACATTTTCTCAGTGTGCCCTTCTCTTACCTGCCAAGCCCATAGCCATAATTCCACCATCATACAAATCAGGCAGTGTTTAAAATGATAGTAGTAGCACAGTGGACAGTCTTTGATCATTATGTTGAGTATGGCTATGAACCAGGAAAGAGATTAGAACATTTAATAATGTATGTACAGCTGATGGTTAGTTTTTTTAATCCAAATTTAATTACCTTACTGGATATTTGATATTTGATTATTTAATCACAGTCATCTTTAACAGCTACGTTGATTGGTGTTTTATCTCCTGTAATCCTTTGATGGGTTTTTTTTGCCTACCATTTCACAGAGGTTTAGACAGCAGTAGTAGTTCCCTAGGAGAGTTTATTGATGAGACAGCCTCTGCAAGATTTTAAAAGTTTTGTTCTTTTATAGACTGATTTAGAAAAACAGATAATTAATAAAAAGAATATATGCATTTGTTGGTAACTGATTTTTAAACCTGGACCTTTCTGGAAGGGCAGCATATAAAAACATCAGTCCCAAGGAGGGGACGACAATACTACCTCACTACTACACCTGCAATGACTGGTTGTTCAAACACAATGGAGTGTGTAAGCTATATGTTTTATAATTCATAATGATAGCCTCAATCATGAAGAAATACTTTTGAAGTTTTTATTTTCCCTTAGAATATCTAGAGTGCTAAATTTTTAACTGCCTTTTTGTTGAGTCAAACTGTGGGATTCTGATCTGTATTAAACTTGTAAGCTCCTCACTGGTGTACTATCATCCTGGAGGGGTGTTGTATGGCTGAGGACTACTGAGTGGCAACACAAAGCTTTTGCAGCCCAGAAGACTTGGAAAAGACCAAAGAAGAGTTAAAAACTGTGATGTCTGGCGGAGCTGTCTGCGGTGGCGGCGGCGCCTCTGGTCTCCCGCGGCCCGGAGCCCGCAGCACCGCCTCTCCCTCCCTGCCGCAGCCCCGCAGCCCAGCAGCGCCCCAGACACACGCCGTCGGGCAGGAGCCGCTCGCTCTCCGGAAAGTGACAACAGAATTCATCGAAGTGAAGAATTTCTTAAGAAGATAACAAAAAGAGAAAGAAAATGCCGGAACCAATCAACGTAACAGTAACTACAATGGATGCTGAGCTGGAAATTTGCCATTCAGCCCAAAACAACTGGCAAACAACTTTTTGACCATGTGGTGAAAATAGTTGGTTTGCGCGAGGTCTGGTTTTTGGGGCTGCAGTATGTAGACAGCAGAGGTTATTCTACATGGCTTCAACTAAATAAAAAGGTGACGCAGCAAGATGTTAAAAAAGAGAAGGATCCTTTACAGTTCAAGTTTAGAGCTAAATTCTTTCCTGAAGATGTTTCTGAGGAATTAATTCAAGAAATAACCCAGAGACTCTTCTTCTTGCAAGTTAAAGAAGCCATCTTAAAGGATGAGATATATTGTCCGACAGAAACTGCAGTTCTTCTGGCTTCCTATGCTGTTCAAGCCAAGTATGGAGATTATAACAAAGAAATTCATAACCCAGGCTACCTGGCTAATGATAGACTCCTACCCCAACGTATTGGAACAACACAAACTAACAAGAACAGTGGGAAGAAAGAATACAGAACTGGCATGAAAAACATAGAGGAATACAAAGGGAGGGTTCTATGATGGACTACCTGAAGATTGCACAAGATCTAGAAATGTATGGAGTCAAGTATTTTGAAATAAAAAAAAGGAAACTGAATTGTGCCTAGGTGTTGATGCTTTGGGTCTGAATATTTATGAGCATGATGACAAGTTAACACCTAAAACTGGTTTTCCGTGGAGTGAAATCAGAAATGTTTCATTTAATGACAAAAAATTTGTTATAAAGCCAATCAATAAAAAGCCACCTGATTTTGGTTTTTATGCCCCTCACCTGAGAGTCAATAAGCAGATTTTGGCCTTATGTATGGGAAACCACGAACTATACATGCGAAGAAGGAAGCCTGATACTATTGAAGTATGACAGATGAGGGCTCAGGCTAGGGAGGAGAAACATCAGAAGCAGTTGGAGAGGGCACAATTAGAGAATAAAAAGAAGAAAAGAGAAATAGCAGAAAAGGAAAGAATAGAATGTGAAAAGGAAGAGCTAATGGAACGTCTAAAACAAATAGAAGAACAGACGATTAAAGCCCAGAAATAACTAGAAGAACAGACGCAAAAAGCTCTAGAACTGGATCAAGAATGAAAACAAGCAAAAGAAGCAGCAGAGTGGCTTGAAAAGGAGCGTCGAGCTGCTGAAGAGGCGAAGTCTGCCATAGCAAAACAAGCTGCCGACCAGAAGAATCAGGAGCAGCTAGCAGCAAAACTTGCTCAATTCACTGCCAAGATTGTACTTCTa
>NM_002906.4
ATATTGCGGAGCTGTCTGCGGTGGCGGCGGCGCCTCTCGTCTCCCGCGGGCCAGCGCTCGCACCACCGCTTCTCCCTCCCTGTCGCAGCCGCGCCGCCGCGCAGCGCCCCAGCCACACGCCGGCGGGCAGAAGCCGCCCGCTCTCCGGAAAGTGATAACAGAATTCATTGAAGTGGAGAATTTTTAAAGAAGGTAACAAAAAGAGAAAGAAAATGCCGAAACCAATCAACGTAAGAGTAACTACAATGGATGCTGAGCTGGAATTTGCCATTCAGCCCAATACAACTGGCAAACAACTTTTTGACCAGGTGGTGAAAACAGTTGGTTTGCGTGAGGTCTGGTTTTTTGGGCTGCAGTATGTAGACAGCAAAGGTTATTCTACATGGCTTAAACTAAATAAAAAGGTAACACAGCAGGATGTTAAAAAAGAGAATCCTTTACAGTTCAAGTTTAGAGCTAAATTCTTTCCTGAAGATGTTTCTGAGGAATTAATTCAAGAAATAACCCAGAGACTCTTCTTCTTGCAAGTTAAAGAAGCCATCTTAAATGATGAGATATATTGCCCGCCAGAAACTGCAGTTCTTTTGGCTTCCTATGCTGTCCAAGCCAAGTATGGAGATTACAATAAAGAGATTCATAAGCCAGGCTACCTGGCTAATGATAGACTCCTACCCCAGCGTGTATTGGAACAACACAAACTAACAAAAGAACAGTGGGAAGAAAGAATACAGAACTGGCATGAAGAACATAGAGGAATGTTAAGGGAGGATTCTATGATGGAATACCTGAAGATTGCACAAGATCTAGAAATGTATGGAGTCAACTATTTTGAAATAAAAAATAAAAAAGGAACTGAATTGTGGCTAGGTGTTGATGCTTTGGGTCTGAATATTTATGAGCATGACGACAAGTTAACACCTAAAATTGGTTTTCCCTGGAGTGAAATCAGAAATATTTCATTTAATGACAAAAAATTTGTTATAAAGCCAATCGACAAAAAGGCACCTGATTTTGTGTTTTATGCACCTCGTCTGAGAATCAATAAGCGGATTTTGGCCTTATGTATGGGAAACCATGAACTATACATGCGAAGAAGGAAGCCTGATACTATTGAAGTACAACAGATGAAGGCTCAGGCTAGGGAGGAGAAACATCAGAAGCAGTTGGAAAGGGCACAATTAgagaatgaaaagaagaaaagagaaatagcagaaaaggaaaaggaaagaatagaacgtgaaaaggaagagctaatggaaCGTCTAAAACAAATTGAAGAGCAGACAATTAAAGCTCAGAAAGAACTAGAAGAACAGACTCGAAAAGCTCTAGAACTGGATCAAGAACGAAAACGAGCAAAAGAAGAAGCAGAACGACTTGAAAAGGAGCGTCGAGCTGCTGAAGAGGCAAAGTCTGCCATAGCAAAACAAGCTGCCGACCAGATGAAGAATCAGGAGCAGCTAGCAGCAGAACTTGCTGAATTCACTGCCAAGATTGCACTTCTAGAGGAAGCCAAGAAGAAAAAGGAAGAGGAAGCTACTGAGTGGCAACACAAAGCTTTTGCAGCCCAGGAAGACTTGGAAAAGACCAAAGAAGAGTTAAAAACTGTGATGTCTGCCccccctccacctccaccaccaccaGTCATTCCTCCAACAGAAAACGAACATGATGAACACGATGAGAATAATGCTGAAGCTAGTGCTGAATTATCAAATGAAGGGGTAATGAACCATAGAAGCGAGGAAGAACGTGTAACCGAAACACAGAAAAATGAGCGTGTTAAGAAGCAACTTCAGGCATTAAGTTCAGAATTAGCCCAAGCCAGAGATGAAACCAAGAAAACACAAAATGATGTTCTTCATGCTGAGAATGTTAAAGCAGGCCGTGATAAGTACAAGACTCTGCGACAGATTCGACAAGGCAATACAAAGCAGCGTATCGATGAGTTTGAAGCAATGTGAGAGCTGTTATTTTGCATATATGTTCTTCATAAGCTGAACCACCAACAGAGAAAAGCAGGCCTTTGCAGATATGATGGAATGCATCCCACCTTGCCAAAGCACTTACACCAGTTTGACTGTGCTAGCTAAAAGACAAATTTAAGGGGAGCTCTTCAACATTAAGGCAGTATGATATCATGCTTGGTTTTCTTTTTTCTTTTGGTCCAGGGAATGGAGAATGGTGTTCCATTGCCTCTTTTCACAttttttttctttttcttttttttttCTGTTGAAGATTAACACTAATTATCACGTCTGACAAATGTGTATGTGTGGTTTCAGTTCTGTGTACATTTTAAAGGATAATGGTGAACATTTTAATGGGTTTCCCTTGCCCTTTCCATATTTAACCTATTTCCACATTCTCTCTCACTCACATTTTCTCAGTGTGCCCTTCTCTTATCTGCCATGTCCATAGCCATAATTCCACCATCATACAGATCAGGCAGTGTTTAAAATGATGGTAGGTAGCACAGTGGACAGTCTTTGATCATCATGTAGAATATGGCTATGAATCAGGAAAGAGATTAGAACATTTAATAATGTATGTACAGCTGGTGCTTAGTTTTTTTTTAATCTAAATTTAATTACCTTATTGGATATTTGATATTTGGTTATTTAATCACAGTCATCTTTAACAGCTTACACTGATTGGTGTTTTATCTCCTGTGATCCTTTGATGGCTTTTTTTGCCTACCATTTCACAGAGGTTTAGACAGCAGTAGTAGCTCCCTAGGAGAGTTTACTGATGAAACAGCCTCTGCAAGATTTTAAAAGTTTTGTTCTTTTATAGACTGATTTAGAAAAACAAATGATTAGTTAAAAAAAGAAAATATACATTTGTTGGTAACTAATGTTATTTTTTAAAACCTGGACCTTTTCTGGAAGGGCAGCATATAAAAACATCAGTCCCGAGGAGGGGACAACAATACTACCTCACTACTACATCTGTGATGACTGGTTGTTCAAACACAATGGAGTGTGTAAGGTATATGTTTTATAATTCATAACCATAGCCTCGATCATCAAGAAATACTTTCGAAATTTCATTTTCCTTCAGAATATCTTAAGAGTGCTAAATTTTTAACTGCCTTTTTGTCGAGTCAAACTGTGGGATTCTGATTTGTATTAAAATTGTAAGCTCCTCACTGGTATACTATCATCCTGGAGGGGTGTTGTATGGCTGAGCAagagagagagagaatgagagagagaCtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtACTCTGTGTGTGTATGAGAGAGAGAAATGCTAACCTTGTAGCATGTGAAGAATGTCTGTACCTTGATACGATAGTTACATAATCAGTATATTTGGTTTCTAGATCACTGTGCTTATTTTGTTTCAATCTCTGACTAAAAATACTTAAATTTGGTTTGTTAATTCTTATTTTAGAAATTATAATTTTAGTTTATATTAATTTCGGTTATAGCTTACTGAAGAAATCTTTCCAGTTAGAAGGAGGTTCTAATATTCACATGTTCTAATACTTTGTTTATTGTAAAACAGCTAAATTTGGAGATACGTAAAGCCTTGTTTTCTCTGTGTGGTTCAGCTACTTTCCATTTGGTATTACACAGTCAAATTTACATTTATCTATTAAAATTGCCATTTTATTAAACATTTTCATGCACAGTAGATTCAAGTTGTGTCTGAAAATATCTCTTGTGCTTTTTTGATTTTGCTGACTTTAAAAGGATTAATCTGGGCAGACATTATGTAAAAGAAAGGTTGCGTTTAATATATTTTTTGAACTTTGTAGGACAAAACATAGCTGGTTAACCTTGAAGTGACTGTTGTACCATGGTTGTGCACATGCTTCAGAATCCTATGGAAGAGAATATTCCTACTTGCAGTACATCAAAGGAATGGATGGTGGACCCTACTATTCATGTTTTGAGACATAAATGTTCACTTTAAAGCAATTGCATAATAGATAAAAACCTGAACTTTCATTGGATTTTTGTTAATTTTCCTCATTTTGAATTATGTGCACTACCATAGCTACATCAGTTTGATACAGTATTGAAAAATTATCAGTTATATTTTGCTGTTTATGATCTATTTGTAGATTAGGATTAAAATGGATTTAATCCATTTTTAAGGCTGTGTGAATTTTTCTAAACAAGAACCATTTGCAATATGGATTTCTTAGAGATTAAACCAATTATAACTTATTAGCAGTCGCGAGCACATGTTCATATAGTCAATGTAAAAATACACTAATGAGTATTTGGTAAATCCCAGTAGGCTTTTACCATTAGCATAATTTTGTGTTGTACAATTAAGTTACAATTACATCTCTAATTTTGGATAATATTCATTGGTTAACAATAAAGTGACAAAAGCTCATGCCTTCAA

Publications

PMID - Link Title