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Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name HIGD1CP4
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:148510998-148511411  UCSC
Coordinates (T2T) chr1:146295934-146296347  UCSC
Coordinates (hg19) chr1:147983222-147983635  UCSC
Strand -
Parental Sequence NM_001109619.3
Parental seq. overlap 346 bp
Parental seq. overlap (%) 48.1%
Genomic Region Intergenic
Retrocopy Summary HIGD1CP4, located on chr1:148510998-148511411, is a retrocopy of the parental gene HIGD1C. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name HIGD1C
Full Name HIG1 hypoxia inducible domain family member 1C
Also known as GM921
Coordinate chr12:50936111-50972592
Strand +
Gene summary Predicted to be involved in mitochondrial respirasome assembly. Predicted to be integral component of membrane. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes HIGD1CP1
Bonobo Pan paniscus HIGD1CP1
Gorilla Gorilla gorilla HIGD1CP3
Orangutan Pongo abelii HIGD1CP1
Dolphin Tursiops truncatus HIGD1CP1
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>HIGD1CP4
GGAGACAGACAGCAGGTGATGGGGCATGCCAAAGAGATAAAAATGTCTTCTGATAATCAGGGGTCAGCAGATGAGTATGAAAGCTAATTATCCCCACTACTCAGGGAATTTAGAGGCTTCCCCTTTTGTCTTTGTAGGAATAGCAGACTTTCTGACTGTAATGTCCAAAGTTCTTTACAAGTTGAAGTACAGAAGAGATCAGAAAATGTCTTACGCACATGAGAGTTGTTATCCAAAGATTTGTCATAGGAGCAGCGACTCTAGGTGTTCTCTATTCTATTTAGAAGAATTACATTAGATTTTGATTCCTCAATGTGGCCAAGAAATAGAGCTACTTGCTGGGAGCAAGAAAGACAACATGACTTCTGGAAACTATTTATTATGAAAAATGAATTTTCATTATGTAGCAAATTA
>NM_001109619.3
ACCACCGACCCACCTCAAGAGCCACAGCCTCTCGGGTCTCCACAGCCCCACTCAGGTCTCACACACAGGCGCAGGGACTAGCCACAGGTGCAGCAACGTCACGTCTTTCCCCTGGGCGCGTGTGCAGCTCGAGGCTTTGCAGGAGGCGCACCTGCGATGGCCTTACCGCCAGCCTCTTGCTGAAGGAACAACAGGAGACAGACAGCAGGTGGCGGGGTGTGCCACAGAGAAAAAAATGTCTTCAGATAACCAGTGGTCAGCAGATGAGGATGAAGGCCAATTATCCCGACTAATCAGGAAATCTAGAGACTCCCCCTTTGTCCCTATAGGTATAGCAGGCTTTGTGACTGTGGTGTCCTGTGGTCTTTACAAGCTAAAGTACAGAAGAGATCAGAAAATGTCAATTCATCTTATTCACATGAGAGTTGCTGCCCAAGGATTTGTTGTTGGAGCTGTGACTCTAGGTGTTCTCTATTCTATGTATAAGGATTACATTAGACCACGATTCTTCAGTGAGTCCAAAAAATGAAGCTTACATGCTGGAAGCAAGAAAGACAAGAAGCTTCTGAAAACTATTTATTATGAAGAATAAATTTTCAATATGTAGCAAATTTTACTACACAAGTGTCACAGAATGCTCATAGCCTTTGTATTTCAAGTCTCAGTGTTTTAAGAAGTTGATTTCCAGATCAACAATCATAAACAGTCAACTCAGAAA

Publications

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