Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

Advanced Search

Summary

Retrocopy Name HMGN3P1
Plot displaying the genomic locations of a retrocopy (in chr1) and its respective parental gene (in chr6). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr1:152399473-152400193  UCSC
Coordinates (T2T) chr1:151536022-151536742  UCSC
Coordinates (hg19) chr1:152371949-152372669  UCSC
Strand +
Parental Sequence NM_004242.4
Parental seq. overlap 639 bp
Parental seq. overlap (%) 73.9%
Genomic Region Intergenic
Retrocopy Summary HMGN3P1, located on chr1:152399473-152400193, is a retrocopy of the parental gene HMGN3. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name HMGN3
Full Name high mobility group nucleosomal binding domain 3
Also known as PNAS-24|PNAS-25|TRIP7
Coordinate chr6:79201245-79234682
Strand -
Gene summary The protein encoded by this gene binds thyroid hormone receptor beta in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is a related pseudogene on chromosome 1. [provided by RefSeq, Jan 2016]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes HMGN3P1
Bonobo Pan paniscus HMGN3P1
Gorilla Gorilla gorilla HMGN3P1
Orangutan Pongo abelii Without Homology
Gibbon Nomascus leucogenys Without Homology
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>HMGN3P1
ATGCCCTGTGCGTGAcAGTTCCAGCCCGTTGCTTTACTTTTTGCTACACCGACATAGCCACTATGCAGAAGAGAAAGTCTCCAGAGAATACAGAGGGCAAAGATGGCTCCAAAGTAACTAAACAGGAGCCCACAAGATGGTCTCCCAGATTGTCAGCAAAACCTCCTCCACCAAAACCTGGACCCAAACCAAGAAAAACATCTGCTAAGAAAGAACCTGGAGCAAAGGTTAGCAGAGGTGCTAAAGAGAAGAAAGGAAAAGTAGGAAGCTGGAAAGGAAGGTACTGCACCAGCTGAAAATGATGAAACTAAAGCTGAAGAGGCACAGAAAACTGAATCTGGAGATAACCAGGGAGAATAAATTGTCATGAAAAACAGGTTAATTTTATGTATCTCTTAGGTGAACTTTTAAAAGCTGTTTTTACTAAGTATTTTCTAAATGCTAATTTTTTAGGACTCTACTAGTTGGCATACAAAAATATGTAAGGATGGACATTTTACCCTCTCATAATCATGCTTTTTGGACATTTCCATCATCCTCAAGTAAAATAAATATCAGTTTAATATTGGAAACTGTGTGTAAGATTGATTCAGCATTCCATGCACTTGCTTTAAAATTTAGTCCTGTGTATACTGTGGTGTTTTTACTGTGCATATTTGAGTTTTTCATGCAGTTTTTCT
>NM_004242.4
GAAGAGGCCGGGCTACGTCGTGCCCTGCGCGTGAgcagctgcagaggcagaggcagcatccagcggcggcgccagcAGTTCCAGTCCGTTGCTTTACTTTTTGCTTCACCGACATAGTCATTATGCCGAAGAGAAAGTCTCCAGAGAATACAGAGGGCAAAGATGGATCCAAAGTAACTAAACAGGAGCCCACAAGACGGTCTGCCAGATTGTCAGCGAAACCTGCTCCACCAAAACCTGAACCCAAACCAAGAAAAACATCTGCTAAGAAAGAACCTGGAGCAAAGATTAGCAGAGGTGCTAAAGGGAAGAAGGAGGAAAAGCAGGAAGCTGGAAAGGAAGGTACTGCACCATCTGAAAATGGTGAAACTAAAGCTGAAGAGGCACAGAAAACTGAATCTGTAGATAACGAGGGAGAATGAATTGTCATGAAAAATTGGGGTTGATTTTATGTATCTCTTGGGACAACTTTTAAAAGCTATTTTTACCAAGTATTTTGTAAATGCTAATTTTTTAGGACTCTACTAGTTGGCATACGAAAATATATAAGGATGGACATTTTATCGTCTCATAGTCATGCTTTTTGGAAATTTACATCATCCTCAAGTAAAATAAATATCAGTTAAATATTGGAAGCTGTGTGTAAGATTGATTCAGCATTCCATGCACTTGCTTTAAAATTTAGTCCTGTGCATACTGTGGTGTTTTTACTGTGCATATTTGAATTTTTCATGCAGTTTTTCTAGAGCAATAATCAGTGGTGCTTTTGTACCTAGGTTTTATGTGATTTTAATGAAACATGGATAGTTGTGGCCACCTGCTGACTATTTGTGGTTTAAAATAAAAGGTTTACTTGTCTGCAGAA

Publications

PMID - Link Title