Imagem 1

Example: RPL12P6, GAPDH, ENSG00000237984

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Summary

Retrocopy Name DPYSL5P1
Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chr2). Each line represents a retrocopy.
Species Homo sapiens
Coordinates (hg38) chr11:58354257-58354473  UCSC
Coordinates (T2T) chr11:58303663-58303879  UCSC
Coordinates (hg19) chr11:58121730-58121946  UCSC
Strand -
Parental Sequence NM_001253723.2
Parental seq. overlap 178 bp
Parental seq. overlap (%) 3.3%
Genomic Region Intergenic
Retrocopy Summary DPYSL5P1, located on chr11:58354257-58354473, is a retrocopy of the parental gene DPYSL5. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name DPYSL5
Full Name dihydropyrimidinase like 5
Also known as CRAM|CRMP-5|CRMP5|CV2|RTSC4|Ulip6
Coordinate chr2:26847995-26950351
Strand +
Gene summary This gene encodes a member of the CRMP (collapsing response mediator protein) family thought to be involved in neural development. Antibodies to the encoded protein were found in some patients with neurologic symptoms who had paraneoplastic syndrome. A pseudogene of this gene is found on chromosome 11. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Dec 2011]

Homology

Species Scientific Name Retrocopy
Chimpanzee Pan troglodytes DPYSL5P1
Bonobo Pan paniscus DPYSL5P1
Gorilla Gorilla gorilla DPYSL5P1
Orangutan Pongo abelii DPYSL5P1
Gibbon Nomascus leucogenys DPYSL5P1
Green monkey Chlorocebus sabaeus Without Homology
Crab-eating macaque Macaca fascicularis Without Homology
Rhesus Macaca mulatta Without Homology
Baboon Papio anubis Without Homology
Golden snub-nosed monkey Rhinopithecus roxellana Without Homology
Marmoset Callithrix jacchus Without Homology
Mouse lemur Microcebus murinus Without Homology
Mouse Mus musculus Without Homology
Rat Rattus norvegicus Without Homology
Chinese hamster Cricetulus griseus Without Homology
Rabbit Oryctolagus cuniculus Without Homology
Pig Sus scrofa Without Homology
Cow Bos taurus Without Homology
Sheep Ovis aries Without Homology
Dolphin Tursiops truncatus Without Homology
Horse Equus caballus Without Homology
Dog Canis familiaris Without Homology
Panda Ailuropoda melanoleuca Without Homology
Cat Felis catus Without Homology
Pale spear-nosed bat Phyllostomus discolor Without Homology
Velvety free-tailed bat Molossus molossus Without Homology
Greater mouse-eared bat Myotis myotis Without Homology
Kuhl's pipistrelle Pipistrellus kuhlii Without Homology
Greater horseshoe bat Rhinolophus ferrumequinum Without Homology
Egyptian rousette Rousettus aegyptiacus Without Homology
Sloth Choloepus didactylus Without Homology
Tasmanian Devil Sarcophilus harrisii Without Homology
Opossum Monodelphis domestica Without Homology
Platypus Ornithorhynchus anatinus Without Homology
Chicken Gallus gallus Without Homology
Turkey Meleagris gallopavo Without Homology
Zebra Finch Taeniopygia guttata Without Homology
Budgerigar Melopsittacus undulatus Without Homology
Painted Turtle Chrysemys picta Without Homology
Lizard Anolis Carolinensis Without Homology
Frog Xenopus tropicalis Without Homology
Zebrafish Danio rerio Without Homology
Drosophila Drosophila melanogaster Without Homology

Expression

Related Sequence

>DPYSL5P1
CCTGTATTCCCACAAGGGCCTCATCATCTCTGGAGCCAATACTGATGTGGTGGTGTGGGACCCTGAAGGCACAAAGATCATCTCAGCCAGCACCTTGGTGCAGGGAGGAAATTTCAATCTCAATGAGAACATGTGCTACTACCGCATGCCTCTGCTCACCATCGACCCTGGGGGTGCTGTGTATGAGAATGGCATCTTCATGTGCACTGAGGGCACT
>NM_001253723.2
GCCTCCCCTTAACCTGCTAGCTGAGGTGGGGAGCGGCGGGAGGAGCCGGCCGCGCGGTGATTGGCGGAGGCCGCTCCCAGCCCCCGACACGCGCCCCTCCCCCGCTCCCCACTCTGGACTCCCGCGCTGGGCGCGCTGAGGCGGCCCCCGAGCGAGCGCGCGTgcagccgccgccgccccgagcacccgcagctccggcgccgcggcGAGACGGAGACGGACCGAGCCACGGGCCCCCGCGGCCGCAGCATCTCGGAGGAGTGGGTGATGGCAGGGGGGTCGGTGGGCTTACCCCTCCCGGGCTAGGACATCCTCCTCTCCCCCTTCTGTTTCTGCGTGAGGCGCACAAAAGGGCGGGGAGCCGGGAACATGCTTGCCAACTCAGCCAGCGTGAGGATCCTCATCAAGGGAGGCAAGGTGGTGAACGATGACTGCACCCACGAGGCTGACGTCTACATCGAGAATGGCATCATCCAGCAGGTGGGCCGCGAGCTCATGATCCCTGGCGGGGCCAAGGTGATTGATGCCACAGGAAAACTGGTGATCCCTGGTGGCATCGACACCAGCACCCACTTCCACCAGACCTTCATGAATGCCACGTGCGTGGACGACTTCTACCATGGGACCAAGGCAGCACTCGTCGGAGGCACCACCATGATCATCGGCCACGTCCTGCCCGACAAGGAGACCTCCCTTGTGGACGCTTATGAGAAGTGCCGAGGTCTGGCCGACCCCAAGGTCTGCTGTGATTACGCCCTCCACGTGGGGATCACCTGGTGGGCACCCAAGGTGAAAGCAGAAATGGAGACACTGGTGAGGGAGAAGGGTGTCAACTCGTTCCAGATGTTCATGACCTACAAGGACCTGTACATGCTTCGAGACAGTGAGCTGTACCAAGTGTTGCACGCTTGCAAGGACATTGGGGCAATCGCCCGCGTCCATGCTGAAAATGGGGAGCTTGTGGCCGAGGGTGCTAAGGAGGCACTGGATTTGGGGATCACAGGCCCAGAAGGAATCGAGATCAGCCGTCCAGAGGAGCTGGAAGCTGAAGCCACTCATCGTGTTATCACCATTGCAAACAGGACTCACTGTCCAATCTACCTGGTCAACGTGTCCAGTATCTCGGCTGGTGACGTTATCGCAGCTGCTAAGATGCAAGGGAAGGTTGTGCTGGCGGAGACCACCACTGCACATGCCACGCTGACAGGCTTACACTACTACCACCAGGACTGGTCCCACGCGGCTGCCTATGTCACGGTGCCTCCCCTGAGACTGGACACCAACACCTCAACCTACCTCATGAGCCTGCTGGCCAATGACACTCTGAACATCGTGGCATCAGATCACCGGCCTTTCACCACAAAGCAGAAAGCTATGGGCAAGGAAGACTTCACCAAGATCCCACATGGAGTGAGTGGCGTGCAGGACCGCATGAGCGTCATCTGGGAGAGAGGAGTGGTTGGAGGAAAGATGGATGAGAACCGTTTTGTGGCCGTTACCAGTTCCAACGCAGCTAAGCTTCTGAACCTGTATCCCCGCAAGGGCCGCATTATTCCCGGAGCCGATGCTGATGTGGTGGTGTGGGACCCAGAAGCCACAAAGACCATCTCAGCCAGCACGCAGGTCCAGGGAGGAGACTTCAACCTGTATGAGAACATGCGCTGCCACGGCGTGCCACTGGTCACCATCAGCCGGGGGCGCGTCGTGTATGAGAACGGCGTCTTCATGTGCGCCGAGGGCACCGGCAAGTTCTGTCCCCTGAGGTCCTTCCCAGACACTGTCTACAAGAAGCTGGTCCAGAGAGAGAAGACTTTAAAGGTTAGAGGAGTGGACCGCACTCCCTACCTGGGGGATGTCGCTGTTGTCGTGCACCCTGGGAAAAAAGAGATGGGAACCCCACTCGCAGACACTCCTACCCGGCCCGTCACCCGGCATGGGGGCATGAGGGACCTTCACGAATCCAGCTTCAGCCTCTCTGGCTCTCAGATCGATGACCATGTTCCAAAGCGAGCTTCAGCTCGGATCCTCGCTCCTCCCGGAGGCAGGTCGAGTGGCATTTGGTAAAGGCATTGCCAAGCCCCCCGAGTGAGGACGCACCGCCGCCACCAGCCCGCAACTCTCCAGCCGAAGCTGCAGGGGCAGGAGAGGCTGGGCTGGGTGGCACACCACCCGAGGGGGGCCCCGGGACCCACGGAGCCCTCCCTATGTCTGCAAAGTGATTCACTGTGCTTCGAGCCAACTCTAACAGGCACTTTGAGATGTGTTCCTCCTGCTGTAGTCCTTTCTGCCTTGGCCTCGGCGGGCTTTTCTGGGGCCCAGGAAGCCCACACTATGCACAGAGCCCAATGCATAGAGCCCTGGCCAGCCCTTCCTCTCACTCCTGCCTCCGCTGGCTTTGGGAAAGCCCAGACTTTAGTGCCCTGCCCCCTGGCTGACTGGCCAGTTGCCCAGAGCACTTTAGCAGATGTGGTTTCAAAGTAAAGGCCTCCTCCCCCACCCCTTAGGCCCCGTGGTGACATTTCCCAAGTCAGACAGATGTCAGCTTCCCAGCCATGCCCAGGACGTCCTATCTCCCCCAACCCACCTCTGGCCCTGTGTAGGGGCAGGGATGGGGGTGGCTGGGACTCCTGGTGCCCCTCGCCAGCTTCTCCTGCGCCCCGCCCACACCCTCGGGGGGTCACAGGCCCAGAAGGGTAGCTGGGCGGGGCTCGAGGCTGGTGCCAGGCGCGTGTAAATGGTTTTGTTTTGCACGTTTGGTTTGCGCAGTAGTTTGGTTTGACTTGTTTGTGCATCCTGTGAAAAATAACGGTGCTTGTGTCACTAGCATAGAATAGCGACAGGAATAGATGTGGTCCTTAGGAGACGCTGCACTTGACACCAACCAGACAGCACAGGGCAGGGGTGGTGGAGGGGGCTGGGCTCACAGGCCTCTCTTTTCCCCGCCTGCAGTCTTCTGGGCTGCGGGAGGCCCTGGCCCTTTCCCCTTCCCCTCCCCTCCTTGTCTAGTTTCCCACATTCCAAAAGGGGGCCTGGGATGCTAGCCCCAGAGATGCCAGCCCTTCAGGAAGCAGGTGTCCTTTCCCCTCTCTGCCCCTGATCACTCCCAGCACTCCCCTTGCCTTCCCCTGTCTTCACCTGCCACcacacacacacacacacacacacacacacacacacacGCACGGCTTCCTATAACTTCTTCCTGCTGGACAGAGACTCAGCGCTCCTCCTGTGTGACTGGCAAGAGGCCTCATGCCTGCTGAGAGAGGAGGAGTGGGAGAGGGGCTTGCCAGACACCAGAGAGGGAGACCCCAGGCCCACAGGACCTGGCTGTCGAACCCGCATTGCTGCTCAGGTGCCGTGATCTCCCGTGGTCGGCACCAGGCCCTTGCCAGCTCATGGCCTCATCTTCTCCCCTGTCCATCCAGGTGGGCCCTCCCTGCTTCTAAAGCCCCACAGAAGTTCCCATGGAAACACTAGAGGCCGGGTGTCTCCTTCCACCTCCAGTGATCTGGGAAGTGACCCAGCCGCCTGCCCTTGTTAAGCCTGGTCTGCCCCGTGGGAAGTGACTTCATGTTGCACATGTGATTTCAGCCCCCGAGGCTTGCGCGAGGCTTCTGGACCCTCGGTTAAAGGTCAGCCCCTggccgggtgcggtggctcacgcctgtaatcccagcactttgggaggccaaggcgggtggatcatggagtcaggagatcgagaccatcctggctaacacggtgaaaccccgtctctactaaaaatacaaaaattacccaggcgtggtggcgggcgcctgtagtcccagctactgaggaggctgaggcaggagaatagcgtgaacccgggaggcggagcttgcagtgagccaagatcacgccactgcacttcagcctggacgacagagtgagactccatctcaaaaaacagacaaacaaaaaaGTCagcccctgcacatctctgtagtgcttttcatgtattcaaaccacttccgtatatgacctctcacttagtcctcatgacaatggagcacttattattcttcccattttacagatgaggaaactaagacccagaaagttcaggtCCTCTGACCCCAGAAGTGTCTGTGATGACCCTCCCAACCTTGGCTATCTACCCCACCTGTGGAGAGGAGGTCTGGGGTGACATCTATTGTAGATCCCACCTGAGAGTTTAACCAATGAGAAGACTTACTTTCCTGGTAGGCAGCCTGCTTTGTTTTGCACAGGAAGATAGATTTTTTTTCTCATCTTTCTTATAAACAACCTCATGCACATTCTGTGTTTGAGCCAAGACTAGTCACCCATTGGGGGCTAACCGTGCAGTGTGAGCTGCGTCCACACCCTCACTTCTCCCTTCACTCCCCCTTTCCTCACTCAGGGGCTGAGAGGACAGAGGTGGTCAGCCGGGGAGCAGAGGTGGCGAAGGGGCTCATGGCAAGTGGCAGCCATTGGAACAGGGGTGAGGACCCAGGCCTGGGAAAGCCACCAGGGATGGGGGAAACCATGACGCCGCCTCCTGGTGCAGTGCACACCATCTCTATCCCTGTCAGCCCTCACTGGGTCATGGGCCTTGGGCAGATGTCAAAGAGCCCAGCAGCAGCGGTGGTGGCCAGCTGGGCAGAGCATCCTTGCTTGGGCTAGGAAAGCTTTACCTTCTCTGAGTGCCTCCGCCTGAGAGATGTGTGACCCGTGGCACCAGGGAACCACGTCTTGGAGTGGTCCACTGTAGGCCATGCGCTTCATCCACCCCCAGTCCCTACATAGGCCCTACCCTTGCCCGGGAGCTTCTAGATAGAAATCAGAAAGAGATTCAAGGAGCCAAATGAGCGGTCAGCCCCCACCATGCACTCCTTGCCCCGTGCAGAGCTCCAGCCAGCTTCGTCACCAGCCCCACTGGCTCCTGGTTGGAACGAAAGGGTCTCTGGTTGCACTGAATGCAGCTCTCAAACTGGTCTTGTACTTGCTGAATAAATACTGTTGTTCTTGCCTTAGCTGCTCTCTAGGTTTGTGGGGTTAAGTTGCCAGAAAATTGTGCTACtgtgtgtgcgtgtgcgtgcgtgtgtgtagtgCTAGGAGTCCACAGTAGGTCTCTGTCAAGCCGATGTCGTGATGAGGGCTTTTCTGATACTGACCCAGAAGCCACAGAACCACAAGGAAACCCAAACCCCCTCCAGCTGCTGAGGCGCAGGCACAGCCTGGGGTCGGATGGAGCCTCCAGCACCCCAGCACCCAGGTGACTTCCCCACTCCCCTGTAAATGTCATGGTGCTAAGACTGTGTCAACCCCAAGACGACACATGGTCCTGTGCTTTGGCCACCGTTTGAGGCAAAAACTAAACAGCCCGACACGTTGTGTTCTGGTGCAGGTTTGTATTAAACTGTAGCTACTTCTCA

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