RCPedia: Rtcs

Summary

Retrocopy Name	CCND2P1	Plot displaying the genomic locations of a retrocopy (in chr11) and its respective parental gene (in chr12). Each line represents a retrocopy.
Species	Homo sapiens
Coordinates (hg38)	chr11:63242878-63247356 UCSC
Coordinates (T2T)	chr11:63232065-63236542 UCSC
Coordinates (hg19)	chr11:63010350-63014828 UCSC
Strand	+
Parental Sequence	NM_001759.4
Parental seq. overlap	3516 bp
Parental seq. overlap (%)	53%
Genomic Region	Intergenic
Retrocopy Summary	CCND2P1, located on chr11:63242878-63247356, is a retrocopy of the parental gene CCND2. Retrocopies of protein-coding genes, also known as processed pseudogenes, are intriguing genomic elements with implications in genome evolution and diseases. While some retrocopies are non-functional, there are examples of retrocopies (retrogenes) acquiring regulatory roles or exhibiting neofunctionalization unrelated to their parental genes.

Parental Gene

Gene Name	CCND2
Full Name	cyclin D2
Also known as	KIAK0002\|MPPH3
Coordinate	chr12:4273762-4305353
Strand	+
Gene summary	The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK4 or CDK6 and functions as a regulatory subunit of the complex, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. Mutations in this gene are associated with megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3 (MPPH3). [provided by RefSeq, Sep 2014]

Homology

Species	Scientific Name	Retrocopy
Chimpanzee	Pan troglodytes	CCND2P1
Bonobo	Pan paniscus	CCND2P1
Gorilla	Gorilla gorilla	CCND2P1
Orangutan	Pongo abelii	CCND2P1
Gibbon	Nomascus leucogenys	CCND2P1
Green monkey	Chlorocebus sabaeus	Without Homology
Crab-eating macaque	Macaca fascicularis	Without Homology
Rhesus	Macaca mulatta	Without Homology
Baboon	Papio anubis	Without Homology
Golden snub-nosed monkey	Rhinopithecus roxellana	Without Homology
Marmoset	Callithrix jacchus	Without Homology
Mouse lemur	Microcebus murinus	Without Homology
Mouse	Mus musculus	Without Homology
Rat	Rattus norvegicus	Without Homology
Chinese hamster	Cricetulus griseus	Without Homology
Rabbit	Oryctolagus cuniculus	Without Homology
Pig	Sus scrofa	Without Homology
Cow	Bos taurus	Without Homology
Sheep	Ovis aries	Without Homology
Dolphin	Tursiops truncatus	Without Homology
Horse	Equus caballus	Without Homology
Dog	Canis familiaris	Without Homology
Panda	Ailuropoda melanoleuca	Without Homology
Cat	Felis catus	Without Homology
Pale spear-nosed bat	Phyllostomus discolor	Without Homology
Velvety free-tailed bat	Molossus molossus	Without Homology
Greater mouse-eared bat	Myotis myotis	Without Homology
Kuhl's pipistrelle	Pipistrellus kuhlii	Without Homology
Greater horseshoe bat	Rhinolophus ferrumequinum	Without Homology
Egyptian rousette	Rousettus aegyptiacus	Without Homology
Sloth	Choloepus didactylus	Without Homology
Tasmanian Devil	Sarcophilus harrisii	Without Homology
Opossum	Monodelphis domestica	Without Homology
Platypus	Ornithorhynchus anatinus	Without Homology
Chicken	Gallus gallus	Without Homology
Turkey	Meleagris gallopavo	Without Homology
Zebra Finch	Taeniopygia guttata	Without Homology
Budgerigar	Melopsittacus undulatus	Without Homology
Painted Turtle	Chrysemys picta	Without Homology
Lizard	Anolis Carolinensis	Without Homology
Frog	Xenopus tropicalis	Without Homology
Zebrafish	Danio rerio	Without Homology
Drosophila	Drosophila melanogaster	Without Homology

Expression

Related Sequence

>CCND2P1
AGCTCTGCTCGCCCACTGCCCAAGAAAACCCCCTATTGAGCCAAAGGAAGGAGATGAGGGGAATGCTTTTGCCTTCCCCCTCCAAAACAAAAACAAAAACAAACACACTTTTCCAGTCCAGAGAAAGCAGGGGAGTGAGGGGTCACAGAGCTGGCCATGCAGCTGCTGGGCTGTGAGGTAGACCCGGTCCTCAGAGCCACGAGGGACTGCAACCTACTCCAAGTTGACCGTGTCCTGAAGAACCTGCTTGCTATCAAGAAGCGCTACCTTCAGTAATGCTCCTACTTCAAGTGTGTGCAGAAGGCCATCCAGCCGTACATGCACAGGATGGTGGCCACTTCTGATGGTGGCCATTTGATTGGTGGCCACTTCTGATGGTGGCCAACATGATTGAACCATTTGGGATGGAAAAGCACCTTTACTCTCAGCCACCTGTTAACTAATGCTGGAGGTCTGTGAGGAACAGAAGTGTGAAGAAAAGGTTTTCCCTCTGGCCACGATTTACCTGGACTGTTTCTTCGCCAGGATCCCAACTTCAAAGTCCCATCTGCAACTCCTGGGTGCTGTCTGCATGTTCCTGGCCTCCAGGCTCAAAGAGTCCAGCCCACTGACTGCCAAAAAGCTGTGCATTTATACCGACAACTCCATCAAGCCTCAGGAGCTGCTGGAGTGGGAACTGGTGGTGTTGGGAAAGTTGAAGTGGAACCTGGCAGCTGTCACGCCTCATGACTTCATTTAGTACATCTTGCACAAGCTGCCCCAGCAGCGGGAGAAGCTGTCTCCAATCTGCAAGCAAGTCCAGAACTTCAATGCTCTGTATGCAATGTACCCGCCATCAATGGTTGCAACTGGAAGTGTAGGAGCAGCTATCTGTGGACTTCAGCAACATGAGGAAGTGAGCTCACTCCCTTGCAATGCCCTGACTGAGCTGCTGGCAAAGATCACCAACACAGATGTGGATTGTCTCAAAAGCCAACCGGGAGCATATTGAGGTGGTCTTCCTCAACAGCCTGCAGCAGTGCCATCAGGACCAGCAGGACAGATCCAAGTCAGAGGATGAACTGGGCCAAGCCAGCACCCCTATAGACCTGTGAGATATCGACCTGTGAGGATGGCAGTCCAGCTGAGAGGCGCATTCATAATCTGCTGTCTCCTTCTTTCTGGTTATGTTTTGTTCTTTGTATCTTAGGGCGAAACTTAAAAAAAAAAACCTCTGCCCCCACATAGTTCGTGTTTAAAGATCTTTTAGAAGTGACAGAAAATAGTCCTATAAAAACAGAATAAGAAAAAGCCTTTGGTGCTTATTTGAAGTACAGCATAAGGGAATCCCTCGTATATTCGAACAGTTATTGTTTGATTATGTAAAAGTAATGGTAAAATGCTTGCAGGAAAACCTGCAGGGTAGTTAGAGAATATGTATGTCTGCAATATGGAAACAAATTAGAGGAGACTTTTTTTTTTCATGTTGTGAGCTAGCACATACACCCCCTTGTAGTATAATTTCAAGGAACTGTGTATGCCATTTATGGCATGATTAGATTATAAAGCAATGAACTCAAGAAGGAATTGGAAATAAGGAAGGACTTGATGGGGAAGGAGTACAAAACAATCTCTCAACATGATTGAACCATTTGGGACGGAGAAGCACCTTTACTCTCAGCCACCTGTTACTAAGTCAGAAGTGTGGTTGGATCTCTATGTTGGGTACTCTTGCTGTCTACATTAGCTGCTACCTAAATAAGATGTTTTATTTTGCCAGTTGGACACAGGTGATTGGCTTCTGGATTTCTTGTCCTGTGACATCTTGCTTCTTCCAAATGCAGTTCATTGCGGACACCACAGTATTGCTATCTAATGGGGGAAATGTAGCTATGGGCTGTAACCAAAACTCACATGAAATGGAGGCAGATGGAGACCTGGGGTGGCATCCAGAATGGAATCTTTTCTCTTATTGTATTAAAAAGGGTAACGTGACCTTGGCATTCCTTCTTAGGAAAAACTAATTTTTGGTGCTGATTGGCATGTCTGCTCCACAGGTTAGCATTGTTCTAAACCATTCCATTCGAAAAGCACTTTGAAAAATTTTTCCCTAGCAATAGATGGCATGGTTTATGCAAGTCATGCTGAATATGGGTTACTCTTCACCTCTGGTATCTGACATTCTTGGGTACACATTTCTGGTGTTCCTACCAGGACACAAGAGACACCTCTTTCTGCTGACATCCCCATCACAACATTCCTCAGAAAAGCCTAAAAACAAAGATCTGTTACCATTCTGATGACACAGAGGATCTTCATTTTATTTCTTTAAATACCTAATTTTACATCTTTATACTTCTTTGGACATGGAAAGTAAAGTTATTGCGGGTGCAAAGACAGATGGCTGAACATCAGGGGGTGGCATTTTGTTTCCTTTTCCTTTTTTGTTTTTGGTAATTTTATTGCAAAGTTGTATTCAGTGTACATGAAgAGGCATTCAGTTAGTAAAGAGGTTGGAGCAACAACTCTTTTTTTTTTTTTTTCACAATTGTAATCGAACAGGTAATGAAGCCATTTGTTAAAATATTTGCCTTTTTAAGTAAAAAAGAAAAATCAGAATGGGGCTACTTTGAAGAATTATTTTATACACAGATTATTTCTTGTTTCAGAGTGCGAAGGTTGAAGATGGAAAAAAATTTAAGAGTCTCTTATTTTTCATTTTGTTTTATTCATGTGTTTCACGGAGTGTACTGCTATTTTGTAAACATTTTTATAGTATATTATTTTATTGCTTAAACTCCAAGTCCTGAAATAGATGGTTGAGATAAGAGTTCTTCATATTGGAAAAACCCTTCTGTAGTTTGTCTTCTTCTGGTTGCATATTCATGGTTGTTGTTTTTTCTTTTCTCTTTTTCCTCTGATCACATTCATCAGAGACAGAGTGTTCTTTACCTCGGGTTTACTGGACAAAATCAACAACTATAAAAGACAATGATTCACACTTTTGTTTTCACAATAACTCACAACCATACAGTTTCTGCTTGGGAGTCTATTAGTGTGAGGAACAGAGAAGCAGGGTGAACAGGGCTAAACTCCTTCTCAGGTGGAAGGCAGGGTGGTCTCAATCCCAGGGACCTTTTTGGTCATGAAGGCCACTGGGCTCCCATTTTGACTCTGGTATGCTCATTATGATGGAAAAAGTACACTGAACCAAGGGATCCTTCCTCCCCTACAAGGAAGATGTTCAGTACAGACATTTATGCAGCAGACTAGGACGTCATAATTTGCACTTGGGTACCAGGTATCAGGAAACAGACTAAAAGGAATTCCAGCAGGCTATATGTGGATCCTCATCTTGTAGCTTTTTCAAAAGCAGGGCATCCTCTGCATTGGGCCCTTTCATCTTGAAACATTTTCCTCCATCTTCCCCCTTCTCTGGAATGGACACTGAGTTGAGGGTCTTCTCTACAGTTTTCCTAGGTCTGAATCTGTGAGTAGATGAATCTGCAGCATGCAGTATTTGCGGTGCTTCCTTCTCCCTCCTCTGTCTCCAACTGCACAGGCAAGCACTATGTAAGCCCAGATTCTCTGCTAAGTGGTTTTCAGGTTTTCAATCACACTGAATTGGCAGGACAAGAAAAATTGTTCAGAGAAGTATGGGAAGATAGTTGAAGGGAGATGAAGAGGCTGCTTCTCTATAGAGATGAGATTCCAGATAAGTCAGTCTCTTGGGAAGTGTGTTTAGAAGGGTTCAAGACTTTGTGAGTAAGCATGACCTTAAAATTCTAGGGGATTTCTGGTAGGACAGTGAGTGGTGAATTCTGAAGTTTTGGAGAGGAAAGTGGAGGAGCCAGCAAGCTAGCTAGCCAGTTTTCTAAAAGCCAACTTTGCACAGCACACTCTTCTGGGCCCTAAGGAGTCCCACAGAATGGGGAAAGTGGGAGCCCTGGAGTTCTTGGGAGTCTTGGAGCCTAAAGAGAAAACGAGGTGCAAATTCATTTCACAGTGACTGACCCTTGAGCTTAAACAGAATCAGCAAATGAAAGAATCTGACAAATAAGGAAAGGCACAAGCCTGCCCGACT

>NM_001759.4
AGAGCGGAGAAGAGCGAGCAGGGGAGAGCGAGACCAGTTTTAAGGGGAGGACCGGTGCGAGTGAGGCAGCCCCGAGGCTCTGCTCGCCCACCACCCAATCCTCGCCTCCCTTCTGCTCCACCTTCTCTCTCTGCCCTCACCTCTCCCCCGAAAACCCCCTATTTAGCCAAAGGAAGGAGGTCAGGGGAACGCTCTCCCCTCCCCTTCCAAAAAACAAAAACAGAAAAACCTTTTTCCAGGCCGGGGAAAGCAGGAGGGAGAGGGGCCGCCGGGCTGGCCATGGAGCTGCTGTGCCACGAGGTGGACCCGGTCCGCAGGGCCGTGCGGGACCGCAACCTGCTCCGAGACGACCGCGTCCTGCAGAACCTGCTCACCATCGAGGAGCGCTACCTTCCGCAGTGCTCCTACTTCAAGTGCGTGCAGAAGGACATCCAACCCTACATGCGCAGAATGGTGGCCACCTGGATGCTGGAGGTCTGTGAGGAACAGAAGTGCGAAGAAGAGGTCTTCCCTCTGGCCATGAATTACCTGGACCGTTTCTTGGCTGGGGTCCCGACTCCGAAGTCCCATCTGCAACTCCTGGGTGCTGTCTGCATGTTCCTGGCCTCCAAACTCAAAGAGACCAGCCCGCTGACCGCGGAGAAGCTGTGCATTTACACCGACAACTCCATCAAGCCTCAGGAGCTGCTGGAGTGGGAACTGGTGGTGCTGGGGAAGTTGAAGTGGAACCTGGCAGCTGTCACTCCTCATGACTTCATTGAGCACATCTTGCGCAAGCTGCCCCAGCAGCGGGAGAAGCTGTCTCTGATCCGCAAGCATGCTCAGACCTTCATTGCTCTGTGTGCCACCGACTTTAAGTTTGCCATGTACCCACCGTCGATGATCGCAACTGGAAGTGTGGGAGCAGCCATCTGTGGGCTCCAGCAGGATGAGGAAGTGAGCTCGCTCACTTGTGATGCCCTGACTGAGCTGCTGGCTAAGATCACCAACACAGACGTGGATTGTCTCAAAGCTTGCCAGGAGCAGATTGAGGCGGTGCTCCTCAATAGCCTGCAGCAGTACCGTCAGGACCAACGTGACGGATCCAAGTCGGAGGATGAACTGGACCAAGCCAGCACCCCTACAGACGTGCGGGATATCGACCTGTGAGGATGCCAGTTGGGCCGAAAGAGAGAGACGCGTCCATAATCTGGTCTCTTCTTCTTTCTGGTTGTTTTTGTTCTTTGTGTTTTAGGGTGAAACTTAAAAAAAAAATTCTGCCCCCACCTAGATCATATTTAAAGATCTTTTAGAAGTGAGAGAAAAAGGTCCTACGAAAACGGAATAATAAAAAGCATTTGGTGCCTATTTGAAGTACAGCATAAGGGAATCCCTTGTATATGCGAACAGTTATTGTTTGATTATGTAAAAGTAATAGTAAAATGCTTACAGGAAAACCTGCAGAGTAGTTAGAGAATATGTATGCCTGCAATATGGGAACAAATTAGAGGAGACTTTTTTTTTTCATGTTATGAGCTAGCACATACACCCCCTTGTAGTATAATTTCAAGGAACTGTGTACGCCATTTATGGCATGATTAGATTGCAAAGCAATGAACTCAAGAAGGAATTGAAATAAGGAGGGACATGATGGGGAAGGAGTACAAAACAATCTCTCAACATGATTGAACCATTTGGGATGGAGAAGCACCTTTGCTCTCAGCCACCTGTTACTAAGTCAGGAGTGTAGTTGGATCTCTACATTAATGTCCTCTTGCTGTCTACAGTAGCTGCTACCTAAAAAAAGATGTTTTATTTTGCCAGTTGGACACAGGTGATTGGCTCCTGGGTTTCATGTTCTGTGACATCCTGCTTCTTCTTCCAAATGCAGTTCATTGCAGACACCACCATATTGCTATCTAATGGGGAAATGTAGCTATGGGCCATAACCAAAACTCACATGAAACGGAGGCAGATGGAGACCAAGGGTGGGATCCAGAATGGAGTCTTTTCTGTTATTGTATTTAAAAGGGTAATGTGGCCTTGGCATTTCTTCTTAGAAAAAAACTAATTTTTGGTGCTGATTGGCATGTCTGGTTCACAGTTTAGCATTGTTATAAACCATTCCATTCGAAAAGCACTTTGAAAAATTGTTCCCGAGCGATAGATGGGATGGTTTATGCAAGTCATGCTGAATACTCCTCCCCTCTTCTCTTTTGCCCCCTCCCTTCCTGCCCCCAGTCTGGGTTACTCTTCGCTTCTGGTATCTGGCGTTCTTTGGTACACAGTTCTGGTGTTCCTACCAGGACTCAAGAGACACCCCTTCCTGCTGACATTCCCATCACAACATTCCTCAGACAAGCCTGTAAACTAAAATCTGTTACCATTCTGATGGCACAGAAGGATCTTAATTCCCATCTCTATACTTCTCCTTTGGACATGGAAAGAAAAGTTATTGCTGGTGCAAAGATAGATGGCTGAACATCAGGGTGTGGCATTTTGTTCCCTTTTCCGtttttttttttttattgttgttgttaattttattGCAAAGTTGTATTCAGCGTACTTGAATTTTTCTTCCTCTCCACTTCTTAGAGGCATTCAGTTAGCAAAGAGGTTGGAGCAACAACTTTTTTTTTTTTTTTTGCACAATTGTAATTGACAGGTAATGAAGCTATTTGTTAAAATATTTGCCTTTTTAAGTAAAAAAGAAAAATCAGAACAGGGCTATTTGAAGAATTATTTTATACACAGATTCTGCCTTGTTTCATAGTATGAGGGTTGAAGACGGAAAACAATCTAAGGGTCTCTCAtttttttaattttgttttgttcagtttggttttttttttttttTGCGCTGCTAAGAAGCTAAAGTCATCCATCCTTATTCACGTTGACAGTACCTAGCTGTAATGTTTCACAGAGTGTGCTGCTATTTTATAAACATTTTTATAATATATTATTTTACTGCTTAAATTCCAAGTCCTGAAGTAGATGGTTGAGATATGAGTTCTTCGTACTGGAAAAGCCCTTCCGTAGTTTGTTTTCTTCTGGTAGCATATTCATGGttgtttttttttttcttttttggttttttggttttttttttttCCTCTGATCACATTCTTCAAAGACGGAGTATTCTTTACCTCAGGTTTACTGGACAAAATCAATAACTACAAAAGGCAATGATTCACGCTTTTGTTTTCATAATACCTCACAACCGTACAGTTTCTGCTTGGGAGCCCATTCGCATGAGGAATACAGAAGCAGTGTGAGCAGGGCTGACTCCCTCTCAGGTGGAAGGCAGGGCGGTCTCACTCCCAGGGACCTTTTTGGTCATGGAGGCCATCGGGCTCCCAGTTAGACCCTGGTATCCTCATCATGATGGAAAAAATACATTGAACCAAGGGATCCTCCCTCCCCTTCAAGGCAGACGTTCAGTACAAACATTTATGCGGTAGGCTCAGATGTCGTAATTTGCACTTAGGTACCAGGTGTCAGGAAACAGACTAAAAAGAATTCCACCAGGCTGTTTGGAGATCCTCATCTTGGAGCTTTTTCAAAAGCGGGGCTTCATCTGCAAAGGGCCCTTTCATCTTGAAGTTTTTCCCCTCCGTCTTTCCCCTCCCCTGGCATGGACACCTTGTGTTTAGGATCATCTCTGCAGGTTTCCTAGGTCTGAATCTGCGAGTAGATGAACCTGCAGCAAGCAGCGTTTATGGTGCTTCCTTCTCCCTCCTCTGTCTCAAACTGCGCAGGCAAGCACTATGCAAGCCCAGGCCCTCTGCTGAGCGGTACTAAACGGTCGGGTTTTCAATCACACTGAATTGGCAGGATAAGAAAAATAGGTCAGATAAGTATGGGATGATAGTTGAAGGGAGGTGAAGAGGCTGCTTCTCTACAGAGGTGAAATTCCAGATGAGTCAGTCTCTTGGGAAGTGTGTTTAGAAGGGTTCAGGACTTTGTGAGTTAGCATGACCCTAAAATTCTAGGGGATTTCTGGTGGGACAATGGGTGGTGAATTCTGAAGTTTTGGAGAGGGAAGTGGAGCAGCCAGCAAGTAAGCTAGCCAGAGTTTTCTCAAGAGCCAGCTTTGCTCAGCACACTCTCCTGGGCCCCAAGGAGTCCCACGGAATGGGGAAAGCGGGAACCCTGGAGTTCTTGGGAATCTTGGAGCCTAAAGAGAAACCGAGGTGCAAATTCATTTCATGGTGACTGACCCTTGAGCTTAAACAGAAGCAGCAAATGAAAGAACCGGACAAATAAGGAAGGGCACAAGCCTACCCGACTCTATTTACAGTCTGTAACTTTCCACTCTTCCTGTAGTCCCGAGGCCCCTGGGTCCTTCTAGCTTTTCTCTTTCCCATCCTTGGGGCCTTGTGTGATGATGGGTGTGGGGCTGCCGATGGGAAAGTCGGGGGTTGTTAGGCTTTTCTGCCTGCTCCTGCTTAAACACAAGAAGGAATCCTGGATTTTGCCCTCTCCTTAGCTCTTAGTCTCTTTGGTAGGAGTTTTGTTCCAGAGGAgctctcccccttggatttgaacttgctctttttgttgttgttgttctttctcttctttttcttACCTCCCACTAAAGGGGTTCCAAATTATCCTGGTCTTTTTCTACCTTGTTGTGTTTCTATCTCGTCTTTACTTCCATCTGTTTGTTTTTTTCTCCATCAGTGGGGGCCGAGTTGTTCCCCCAGCCTGCCAAATTTTGATCCTTCCCCTCTTTTGGCCAAATCCTAGGGGGAAGAAATCCTAGTATGCCAAAAATATATGCTAAGCATAATTAAACTCCATGCGGGTCCATAACAGCCAAGAAGCCTGCAGGAGAAAGCCAAGGGCAGTTCCCTCCGCAGAACACCCCATGCGTGCTGAGAGGCGAGCTCCTTGAAGAAGGGGCTGTTCTTCCAGGAGGCCTTATTTTGAACTGCCTCAGGACCCCACTGGAGAGCACAGCATGCCTTACTACTGGGTCATCCTTGGTCTATGTGCTCTGTACTGGAGGCTCTGTTCTGCCTCTTATCAGCCAGGTCAGGGGCACACATGGCTTAAGTGACAAAGCCAGAGGAGAAgacaaccctgacagcatcacgctgcatcccattgctagcaggattggcAACTCTTCAGACGGAGCTGCGCTTCCCTGCAGTCTAGCACCTCTAGGGCCTCTCCAGACTGTGCCCTGGGAGCTCTGGGACTGAAAGGTTAAGAACATAAGGCAGGATCAGATGACTCTCTCCAAGAGGGCAGGGGAATTTTCTCTCCATGGGCCACAGGGGACAGGGCTGGGAGAAGAAATAGACTTGCACCTTATGTCATGTAAATAATTGATTTTCTAGTTCAAGAAGATAATATTGGTAGTGTGGGAATTGGAGGTAGGAAGGGGAGGAAGTCTGAGTAAGCCAGTTGGCTTCTAAGCCAAAAGGATTCCTCTTTGTTTATCTCTGAGACAGTCCAACCTTGAGAATAGCTTTAAAAGGGAAATTAATGCTGAGATGATAAAGTCCCCTTAAGCCAACAAACCCTCTGTAGCTATAGAATGAGTGCAGGTTTCTATTGGTGTGGACTCAGAGCAATTTACAAGAGCTGTTCATGCAGCCATCCATTTGTGCAAAATAGGGTAAGAAGATTCAAGAGGATATTTATTACTTCCTCATACCACATGGCttttgatgattctggattctaaacaacccagaatggtcatttcaggcacaacgatactacattcgtgtgtgtctgcttttaaacttggctGGGCTATCAGACCCTATTCTCGGCTCAGGTTTTGAGAAGCCATCAGCAAATGTGTACGtgcatgctgtagctgcagcctgcatcccttcgcctgcagcctACTTTGGGGAAATAAAGTGCCTTACTGACTGTAGCCATTACAGTATCCAATGTCTTTTGACAGGTGCCTGTCCTTGAAAAACAAAGTTTCTATTTTTATTTTTAATTGGTTTAGTTCTTAACTGCTGGCCAACTCTTACATCCCCAGCAAATCATCGGGCCATTGGATTTTTTCCATTATGTTCATCACCCTTATATCATGTACCTCAGAtctctctctctctcctctctctcAGTTATGTAGtttcttgtcttggacttttttttttcttttctttttctttttttttttGCTTTAAAACAAGTGTGATGCCATATCAAGTCCATGTTATTCTCTCACAGTGTACTCTATAAGAGGTGTGGGTGTCTGTTTGGTCAGGATGTTAGAAAGTGCTGATAAGTAGCATGATCAGTGTATGCGAAAAGGTTTTTAGGAAGTATGGCAAAAATGTTGTATTGGCTATGATGGTGACATGATATAGTCAGCTGCCTTTTAAGAGGTCTTATCTGTTCAGTGTTAAGTGATTTAAAAAAATAATAACCTGTTTTCTGACTAGTTTAAAGATGGATTTGAAAATGGTTTTGAATGCAATTAGGTTATGCTATTTGGACAATAAACTCACCTTGACCTAAA

>NM_001759.4 

AGAGCGGAGAAGAGCGAGCAGGGGAGAGCGAGACCAGTTTTAAGGGGAGGACCGGTGCGAGTGAGGCAGCCCCGAGGCTCTGCTCGCCCACCACCCAATCCTCGCCTCCCTTCTGCTCCACCTTCTCTCTCTGCCCTCACCTCTCCCCCGAAAACCCCCTATTTAGCCAAAGGAAGGAGGTCAGGGGAACGCTCTCCCCTCCCCTTCCAAAAAACAAAAACAGAAAAACCTTTTTCCAGGCCGGGGAAAGCAGGAGGGAGAGGGGCCGCCGGGCTGGCCATGGAGCTGCTGTGCCACGAGGTGGACCCGGTCCGCAGGGCCGTGCGGGACCGCAACCTGCTCCGAGACGACCGCGTCCTGCAGAACCTGCTCACCATCGAGGAGCGCTACCTTCCGCAGTGCTCCTACTTCAAGTGCGTGCAGAAGGACATCCAACCCTACATGCGCAGAATGGTGGCCACCTGGATGCTGGAGGTCTGTGAGGAACAGAAGTGCGAAGAAGAGGTCTTCCCTCTGGCCATGAATTACCTGGACCGTTTCTTGGCTGGGGTCCCGACTCCGAAGTCCCATCTGCAACTCCTGGGTGCTGTCTGCATGTTCCTGGCCTCCAAACTCAAAGAGACCAGCCCGCTGACCGCGGAGAAGCTGTGCATTTACACCGACAACTCCATCAAGCCTCAGGAGCTGCTGGAGTGGGAACTGGTGGTGCTGGGGAAGTTGAAGTGGAACCTGGCAGCTGTCACTCCTCATGACTTCATTGAGCACATCTTGCGCAAGCTGCCCCAGCAGCGGGAGAAGCTGTCTCTGATCCGCAAGCATGCTCAGACCTTCATTGCTCTGTGTGCCACCGACTTTAAGTTTGCCATGTACCCACCGTCGATGATCGCAACTGGAAGTGTGGGAGCAGCCATCTGTGGGCTCCAGCAGGATGAGGAAGTGAGCTCGCTCACTTGTGATGCCCTGACTGAGCTGCTGGCTAAGATCACCAACACAGACGTGGATTGTCTCAAAGCTTGCCAGGAGCAGATTGAGGCGGTGCTCCTCAATAGCCTGCAGCAGTACCGTCAGGACCAACGTGACGGATCCAAGTCGGAGGATGAACTGGACCAAGCCAGCACCCCTACAGACGTGCGGGATATCGACCTGTGAGGATGCCAGTTGGGCCGAAAGAGAGAGACGCGTCCATAATCTGGTCTCTTCTTCTTTCTGGTTGTTTTTGTTCTTTGTGTTTTAGGGTGAAACTTAAAAAAAAAATTCTGCCCCCACCTAGATCATATTTAAAGATCTTTTAGAAGTGAGAGAAAAAGGTCCTACGAAAACGGAATAATAAAAAGCATTTGGTGCCTATTTGAAGTACAGCATAAGGGAATCCCTTGTATATGCGAACAGTTATTGTTTGATTATGTAAAAGTAATAGTAAAATGCTTACAGGAAAACCTGCAGAGTAGTTAGAGAATATGTATGCCTGCAATATGGGAACAAATTAGAGGAGACTTTTTTTTTTCATGTTATGAGCTAGCACATACACCCCCTTGTAGTATAATTTCAAGGAACTGTGTACGCCATTTATGGCATGATTAGATTGCAAAGCAATGAACTCAAGAAGGAATTGAAATAAGGAGGGACATGATGGGGAAGGAGTACAAAACAATCTCTCAACATGATTGAACCATTTGGGATGGAGAAGCACCTTTGCTCTCAGCCACCTGTTACTAAGTCAGGAGTGTAGTTGGATCTCTACATTAATGTCCTCTTGCTGTCTACAGTAGCTGCTACCTAAAAAAAGATGTTTTATTTTGCCAGTTGGACACAGGTGATTGGCTCCTGGGTTTCATGTTCTGTGACATCCTGCTTCTTCTTCCAAATGCAGTTCATTGCAGACACCACCATATTGCTATCTAATGGGGAAATGTAGCTATGGGCCATAACCAAAACTCACATGAAACGGAGGCAGATGGAGACCAAGGGTGGGATCCAGAATGGAGTCTTTTCTGTTATTGTATTTAAAAGGGTAATGTGGCCTTGGCATTTCTTCTTAGAAAAAAACTAATTTTTGGTGCTGATTGGCATGTCTGGTTCACAGTTTAGCATTGTTATAAACCATTCCATTCGAAAAGCACTTTGAAAAATTGTTCCCGAGCGATAGATGGGATGGTTTATGCAAGTCATGCTGAATACTCCTCCCCTCTTCTCTTTTGCCCCCTCCCTTCCTGCCCCCAGTCTGGGTTACTCTTCGCTTCTGGTATCTGGCGTTCTTTGGTACACAGTTCTGGTGTTCCTACCAGGACTCAAGAGACACCCCTTCCTGCTGACATTCCCATCACAACATTCCTCAGACAAGCCTGTAAACTAAAATCTGTTACCATTCTGATGGCACAGAAGGATCTTAATTCCCATCTCTATACTTCTCCTTTGGACATGGAAAGAAAAGTTATTGCTGGTGCAAAGATAGATGGCTGAACATCAGGGTGTGGCATTTTGTTCCCTTTTCCGtttttttttttttattgttgttgttaattttattGCAAAGTTGTATTCAGCGTACTTGAATTTTTCTTCCTCTCCACTTCTTAGAGGCATTCAGTTAGCAAAGAGGTTGGAGCAACAACTTTTTTTTTTTTTTTTGCACAATTGTAATTGACAGGTAATGAAGCTATTTGTTAAAATATTTGCCTTTTTAAGTAAAAAAGAAAAATCAGAACAGGGCTATTTGAAGAATTATTTTATACACAGATTCTGCCTTGTTTCATAGTATGAGGGTTGAAGACGGAAAACAATCTAAGGGTCTCTCAtttttttaattttgttttgttcagtttggttttttttttttttTGCGCTGCTAAGAAGCTAAAGTCATCCATCCTTATTCACGTTGACAGTACCTAGCTGTAATGTTTCACAGAGTGTGCTGCTATTTTATAAACATTTTTATAATATATTATTTTACTGCTTAAATTCCAAGTCCTGAAGTAGATGGTTGAGATATGAGTTCTTCGTACTGGAAAAGCCCTTCCGTAGTTTGTTTTCTTCTGGTAGCATATTCATGGttgtttttttttttcttttttggttttttggttttttttttttCCTCTGATCACATTCTTCAAAGACGGAGTATTCTTTACCTCAGGTTTACTGGACAAAATCAATAACTACAAAAGGCAATGATTCACGCTTTTGTTTTCATAATACCTCACAACCGTACAGTTTCTGCTTGGGAGCCCATTCGCATGAGGAATACAGAAGCAGTGTGAGCAGGGCTGACTCCCTCTCAGGTGGAAGGCAGGGCGGTCTCACTCCCAGGGACCTTTTTGGTCATGGAGGCCATCGGGCTCCCAGTTAGACCCTGGTATCCTCATCATGATGGAAAAAATACATTGAACCAAGGGATCCTCCCTCCCCTTCAAGGCAGACGTTCAGTACAAACATTTATGCGGTAGGCTCAGATGTCGTAATTTGCACTTAGGTACCAGGTGTCAGGAAACAGACTAAAAAGAATTCCACCAGGCTGTTTGGAGATCCTCATCTTGGAGCTTTTTCAAAAGCGGGGCTTCATCTGCAAAGGGCCCTTTCATCTTGAAGTTTTTCCCCTCCGTCTTTCCCCTCCCCTGGCATGGACACCTTGTGTTTAGGATCATCTCTGCAGGTTTCCTAGGTCTGAATCTGCGAGTAGATGAACCTGCAGCAAGCAGCGTTTATGGTGCTTCCTTCTCCCTCCTCTGTCTCAAACTGCGCAGGCAAGCACTATGCAAGCCCAGGCCCTCTGCTGAGCGGTACTAAACGGTCGGGTTTTCAATCACACTGAATTGGCAGGATAAGAAAAATAGGTCAGATAAGTATGGGATGATAGTTGAAGGGAGGTGAAGAGGCTGCTTCTCTACAGAGGTGAAATTCCAGATGAGTCAGTCTCTTGGGAAGTGTGTTTAGAAGGGTTCAGGACTTTGTGAGTTAGCATGACCCTAAAATTCTAGGGGATTTCTGGTGGGACAATGGGTGGTGAATTCTGAAGTTTTGGAGAGGGAAGTGGAGCAGCCAGCAAGTAAGCTAGCCAGAGTTTTCTCAAGAGCCAGCTTTGCTCAGCACACTCTCCTGGGCCCCAAGGAGTCCCACGGAATGGGGAAAGCGGGAACCCTGGAGTTCTTGGGAATCTTGGAGCCTAAAGAGAAACCGAGGTGCAAATTCATTTCATGGTGACTGACCCTTGAGCTTAAACAGAAGCAGCAAATGAAAGAACCGGACAAATAAGGAAGGGCACAAGCCTACCCGACTCTATTTACAGTCTGTAACTTTCCACTCTTCCTGTAGTCCCGAGGCCCCTGGGTCCTTCTAGCTTTTCTCTTTCCCATCCTTGGGGCCTTGTGTGATGATGGGTGTGGGGCTGCCGATGGGAAAGTCGGGGGTTGTTAGGCTTTTCTGCCTGCTCCTGCTTAAACACAAGAAGGAATCCTGGATTTTGCCCTCTCCTTAGCTCTTAGTCTCTTTGGTAGGAGTTTTGTTCCAGAGGAgctctcccccttggatttgaacttgctctttttgttgttgttgttctttctcttctttttcttACCTCCCACTAAAGGGGTTCCAAATTATCCTGGTCTTTTTCTACCTTGTTGTGTTTCTATCTCGTCTTTACTTCCATCTGTTTGTTTTTTTCTCCATCAGTGGGGGCCGAGTTGTTCCCCCAGCCTGCCAAATTTTGATCCTTCCCCTCTTTTGGCCAAATCCTAGGGGGAAGAAATCCTAGTATGCCAAAAATATATGCTAAGCATAATTAAACTCCATGCGGGTCCATAACAGCCAAGAAGCCTGCAGGAGAAAGCCAAGGGCAGTTCCCTCCGCAGAACACCCCATGCGTGCTGAGAGGCGAGCTCCTTGAAGAAGGGGCTGTTCTTCCAGGAGGCCTTATTTTGAACTGCCTCAGGACCCCACTGGAGAGCACAGCATGCCTTACTACTGGGTCATCCTTGGTCTATGTGCTCTGTACTGGAGGCTCTGTTCTGCCTCTTATCAGCCAGGTCAGGGGCACACATGGCTTAAGTGACAAAGCCAGAGGAGAAgacaaccctgacagcatcacgctgcatcccattgctagcaggattggcAACTCTTCAGACGGAGCTGCGCTTCCCTGCAGTCTAGCACCTCTAGGGCCTCTCCAGACTGTGCCCTGGGAGCTCTGGGACTGAAAGGTTAAGAACATAAGGCAGGATCAGATGACTCTCTCCAAGAGGGCAGGGGAATTTTCTCTCCATGGGCCACAGGGGACAGGGCTGGGAGAAGAAATAGACTTGCACCTTATGTCATGTAAATAATTGATTTTCTAGTTCAAGAAGATAATATTGGTAGTGTGGGAATTGGAGGTAGGAAGGGGAGGAAGTCTGAGTAAGCCAGTTGGCTTCTAAGCCAAAAGGATTCCTCTTTGTTTATCTCTGAGACAGTCCAACCTTGAGAATAGCTTTAAAAGGGAAATTAATGCTGAGATGATAAAGTCCCCTTAAGCCAACAAACCCTCTGTAGCTATAGAATGAGTGCAGGTTTCTATTGGTGTGGACTCAGAGCAATTTACAAGAGCTGTTCATGCAGCCATCCATTTGTGCAAAATAGGGTAAGAAGATTCAAGAGGATATTTATTACTTCCTCATACCACATGGCttttgatgattctggattctaaacaacccagaatggtcatttcaggcacaacgatactacattcgtgtgtgtctgcttttaaacttggctGGGCTATCAGACCCTATTCTCGGCTCAGGTTTTGAGAAGCCATCAGCAAATGTGTACGtgcatgctgtagctgcagcctgcatcccttcgcctgcagcctACTTTGGGGAAATAAAGTGCCTTACTGACTGTAGCCATTACAGTATCCAATGTCTTTTGACAGGTGCCTGTCCTTGAAAAACAAAGTTTCTATTTTTATTTTTAATTGGTTTAGTTCTTAACTGCTGGCCAACTCTTACATCCCCAGCAAATCATCGGGCCATTGGATTTTTTCCATTATGTTCATCACCCTTATATCATGTACCTCAGAtctctctctctctcctctctctcAGTTATGTAGtttcttgtcttggacttttttttttcttttctttttctttttttttttGCTTTAAAACAAGTGTGATGCCATATCAAGTCCATGTTATTCTCTCACAGTGTACTCTATAAGAGGTGTGGGTGTCTGTTTGGTCAGGATGTTAGAAAGTGCTGATAAGTAGCATGATCAGTGTATGCGAAAAGGTTTTTAGGAAGTATGGCAAAAATGTTGTATTGGCTATGATGGTGACATGATATAGTCAGCTGCCTTTTAAGAGGTCTTATCTGTTCAGTGTTAAGTGATTTAAAAAAATAATAACCTGTTTTCTGACTAGTTTAAAGATGGATTTGAAAATGGTTTTGAATGCAATTAGGTTATGCTATTTGGACAATAAACTCACCTTGACCTAAA

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